The invention discloses a dry-and-wet neutral detergent fiber (NDF) macromolecular self-adhesive waterproof coiled material, as well as a production process and production equipment of the NDF macromolecular self-adhesive waterproof coiled material. The dry-and-wet NDF macromolecular self-adhesive waterproof coiled material is prepared from 20 parts of No.10 asphalt, 50 parts of No.100 asphalt, 6 parts of thermoplastic styrene butadiene rubber, 6 parts of styrene butadiene rubber, 5 parts of a softener, 3 parts of a curing agent, 4 parts of a reactant, 3.5 parts of a thickener and 2.5 parts of C9 resin. The production process comprises the steps of material blending, base stablizing, oil dipping and coating, film laminating, traction, compaction and the like. The production equipment sequentially comprises a raw material tank, an oxidation tank, a colloid mill, an oil dipping groove, an oil coating groove, a base drying machine, a base stopping machine, a base lap joint machine, a base unfolding device and the like. The dry-and-wet NDF macromolecular self-adhesive waterproof coiled material has the advantages of high creep property and adaptability of a product, high tensile performance, high elongation percentage and high performance; when being punctured by a sharp object, the product can be automatically repaired, so that water seepage is avoided, and the waterproof performance is improved; the process is simple and easy to operate, and easy to control.