The invention relates to a fertilizer-mix pesticide with functions of disease controlling, pest controlling, weed controlling, and fertilizer efficiency enhancing. The fertilizer-mix pesticide comprises pesticidal, bactericidal, and herbicidal active components, and a fertilizer efficiency enhancer. With added necessary auxiliary components, a required dosage form is formed. The fertilizer-mix pesticide can be applied on wheat, rice, corn, sugarcane, eucalyptus, tobacco, potato, sweet potato, and vegetables. With the pesticide, underground pests can be dispelled and killed, soil-borne diseases can be controlled, the occurrence of seedling-stage pests and diseases can be controlled, weeds can be effectively prevented and removed, nitrogen fertilizer utilization rate can be improved, nitrogen effective period is prolonged, and phosphate fertilizer and potash fertilizer are activated. With the pesticide, multiple functions such as disease controlling, pest controlling, weed controlling, fertilizer effect enhancing, and the like are provided.