A
system for the automated detection of
lung anomalies using
deep learning-based
computed tomography image reconstruction, comprising: a
computed tomography unit configured to generate raw projection data corresponding to a
thoracic region of a subject; a preprocessing unit operationally coupled to the
computed tomography acquisition unit and configured to convert the raw projection data into normalized projection representations through logarithmic transformation,
scatter correction, and geometric calibration;a reconstruction processor that is communicatively linked to the preprocessing unit and configured to reconstruct
volumetric image data from the normalized projection representations using a trained deep
neural network architecture consisting of a multitude of convolutional
layers arranged for
feature extraction in
projection space,
domain transformation, and image space refinement; a segmentation processor that is operationally coupled to the reconstruction processor and configured to segment the reconstructed
volumetric image data into
lung regions and subregions based on learned spatial features; a
feature extraction processor configured to derive spatial, morphological, and textual features at various scales from the segmented
lung regions;a classification processor that is operationally coupled to the
feature extraction processor and configured to identify and classify lung anomalies based on the extracted features using a trained neural network; and a
visualization unit configured to display detected anomalies and generate diagnostic outputs, wherein the reconstruction processor and the classification processor are further configured to work together so that the classification results influence the refinement of the reconstruction.