66 results about "Radiation Dosages" patented technology

Provided are methods and compositions for enhancing radiotherapy in various cancers by administering dopamine receptor (DRD2)‐binding phenylpiperazine derivatives such as brexpiprazole, cariprazine, pipamperone, and perospirone. In vitro studies show that combining these agents with ionizing radiation (e.g., 5 Gy) significantly reduces cancer cell survival, suppresses metastatic and stemness markers (e.g., CD44, MMP‑2, Snail, Nanog), and promotes apoptosis. Fractionated or single‐fraction radiation regimens can be paired with DRD2 antagonists to lower treatment‐resistant phenotypes, decrease the likelihood of recurrence, and potentially reduce necessary radiation dosages. The approach applies to breast, prostate, lung, pancreatic, and brain cancers, among others. Depending on tumor characteristics, additional chemotherapeutic or immunotherapeutic agents may further improve outcomes.

A method, system, and device for ultra-low-dose imaging of oral cone-beam computed tomography (CBCT) are provided. The method encompasses high-dose oral CBCT image data acquisition, data segmentation processing, three-dimensional (3D) reconstruction processing, model training, image data input, image enhancement, and image data output. Specifically, the process involves performing 3D reconstruction on 2D projection data of oral CBCT acquired in ultra-low-dose mode to obtain ultra-low-dose oral CBCT 3D reconstructed image data. This ultra-low-dose oral CBCT 3D reconstructed image data is then input into the oral CBCT ultra-low-dose imaging enhancement network model, from which high-quality oral CBCT image data is output for subsequent clinical diagnosis and treatment processes. This method significantly reduces the radiation dose of imaging while ensuring imaging quality, accelerates imaging speed, and enhances the safety of oral CBCT imaging, holding broad clinical application prospects.

The ability to improve the adjusting of technical parameters in therapy plans found by Pareto navigation constitutes a technical problem, along with facilitating the decision-making of the planner (also called user) and simplifying the mathematical calculation of the solution. Proposed is a way to find and establish a therapy plan among a plurality of plan proposals for cancer therapy, each plan proposal representing as a solution one point in a navigation space (N) containing a plurality of setting parameters and establishing in a machine space (M) a setting for radiation doses to be administered by a radiation therapy machine for cancer therapy. The navigation space (N) contains at least one Pareto front (200) behind or on which available treatment plans are located as possible solutions and among which a user navigates, whereby a first plurality of available solutions calculated in advance as plan proposals is provided in a memory and retrieved or read out from the memory for display. The retrieved or read-out plan proposals are shown on a display and used by the user for navigation, whereby a large number of Pareto-optimal solutions with physical values or evaluations of dose values can be found among the points. Moreover, such solutions are also shown that are almost Pareto-optimal, within a tolerance range of at most ±5% from the Pareto optimum. In this way, a large first set of points with the physical values or evaluations of dose values is created and then stored in the memory. From this, a second set of points is calculated, which defines clinical targets. A decision space (D) is provided and shown in which at least the clinical targets are plotted on target axes (76, 876, 776). This is without the possibility of navigating in the decision space (D) on the target axes of the clinical targets, whereas binary selections in the decision space are made in the manner of restrictors to specify which plan proposals are not used as therapy plans. This enables a desired therapy plan to be found and determined from the large number of plan proposals.

This invention provides a four-dimensional CT reconstruction method based on real-time kV image-driven reconstruction, including data preprocessing and four-dimensional CT reconstruction. Data preprocessing includes respiratory phase synchronization, spatial resampling, and geometric consistency registration and clipping. Four-dimensional CT reconstruction is implemented using a deep learning model based on a three-dimensional U-Net architecture. The model training adopts a supervised learning paradigm, using normalized prior three-dimensional CT volume data and corresponding two-dimensional kV projection images as joint inputs. Through multi-scale feature encoding and decoding structures, the model learns the mapping relationship between the two-dimensional projection images and the three-dimensional volume data, thereby predicting and outputting the three-dimensional CT volume data under the current respiratory phase. This application achieves an end-to-end closed loop from two-dimensional projection to four-dimensional CT to dose assessment, reducing the radiation dose required for image reconstruction, improving reconstruction speed, and ensuring spatial accuracy and temporal continuity, possessing feasibility and practical value for clinical application.

The invention relates to a radiation treatment planning method and apparatus. The control circuit may be configured to generate a virtual target volume from the target volume of the particular patient and then generate a virtual bolus from the virtual target volume. The control circuit may then determine a corresponding radiation dose using the target volume and the virtual bolus, thereby optimizing a radiation treatment plan for a particular patient.

1. The name of the design product: radiation dose monitoring graphical user interface for electronic equipment. 2. The use of the design product: radiation dose monitoring for electronic equipment. 3. The design points of the design product: the content of the displayed graphical interface. 4. The picture or photo that best indicates the design points: interface change state diagram. 5. The use of the graphical user interface: the graphical user interface of the present design is used for radiation dose monitoring of electronic equipment. 6. Other circumstances that need to be explained: the front view is the initial interface, and the front view slides down to enter the interface change state diagram.

The invention provides a sample irradiation damage testing device and system under a hard XFEL condition, and relates to an intense light source experiment technology and radiation dosimetry. The device comprises a vacuum cavity, a posture adjusting mechanism, a dose testing mechanism, a sample table and a sample testing mechanism are arranged in an inner cavity of the vacuum cavity, the posture adjusting mechanism is used for clamping an attenuation slice, and the sample table is used for placing a sample; when an irradiation damage test is carried out, an XFEL light path is formed in the inner cavity of the vacuum cavity; and the attenuation sheet, the dose testing mechanism, the sample and the sample testing mechanism are sequentially located in a light path of the XFEL along the propagation direction of the XFEL. According to the invention, the irradiation dose of XFEL can be continuously, rapidly and accurately adjusted in a vacuum environment, and the tolerance limit of a sample can be given in real time.

The invention discloses a time correction method and device, a computer storage medium and a digital PET system. The time correction method comprises the following steps: step S100, carrying out in-ring time correction on crystal strips of a plurality of detection rings in sequence to obtain in-ring time correction values of all the crystal strips; s200, all coincidence events between every two adjacent detection rings are obtained in sequence, and the event arrival time of each coincidence event on the crystal strip is obtained; and S300, carrying out inter-ring time correction on the plurality of detection rings according to the position of the current to-be-calibrated ring, the in-ring time correction value and the average value or weighted value of the difference value of the arrival time of the two single events of each coincidence event. According to the invention, the overall time correction quality of the digital PET system can be improved, the image quality can be improved, the radiation dose can be reduced, and the inter-ring time correction of the long-axis PET can be realized at the cost as low as possible.

A method for varying the radiation dosage in vivo during brachytherapy treatment is provided. The method includes infinitely varying the volume of radiation exposed to the patient. This volume variation feature is utilized as clinically indicated and can further reduce the risk of slippage of the device in situ.

The invention provides a separable microcatheter and stent conveying system and method, and belongs to the technical field of neural intervention and vascular intervention. The system comprises a separable micro-catheter which is formed by detachably connecting a near-section micro-catheter (1) and a far-section micro-catheter (2) through a physical clamping structure; the stent conveying system comprises a conveying guide wire (3) and an intravascular stent (4), and the conveying guide wire (3) is provided with an anchoring stent (31) matched with the limiting cavity of the far-section micro catheter (2). The guide wire, the catheter and the stent conveying system are integrated, so that the vascular interventional operation process is obviously optimized. The system adopts a separable microcatheter design and a mechanical anchoring structure, so that a guide wire and a catheter do not need to be exchanged for many times in the operation process, and the number of times of instrument operation is fundamentally reduced. According to the invention, the operation time is shortened, the exposure time of an operator and a patient under X-rays is directly reduced, and the radiation dose is effectively controlled.

Methods and systems of radiosurgical treatment include rotating one or both of a first gantry component and a second gantry component while transmitting a therapeutic treatment beam so as to deliver a therapeutic radiation dose to a target tissue of a patient from one or more arcs extending along a treatment sphere. The first gantry component is rotatable about a first axis and a second gantry component is interfaced with the first gantry component such that rotation of the first gantry component rotates both the first and second gantry components about the first axis. The second gantry component is independently rotatable about a second axis. The method includes coordinating movement of the first and second gantry components along the respective first and second axes so as to allow a trajectory of the therapeutic treatment beam to intersect the target tissue from multiple directions along the treatment sphere.

The invention relates to a nuclear accident emergency exercise system based on simulation data transmission and feedback, and the system comprises a general control module which is used for receiving an external accident simulation result, constructing dose data and nuclide concentration distribution data required by simulation exercise according to the accident simulation result, and transmitting the dose data and the nuclide concentration distribution data to the general control module; the accident simulation result at least comprises radiation dose distribution and nuclide concentration; the data transmission module is used for data transmission between the master control module and the handheld monitoring module; the handheld monitoring module is used for handheld operation of exercise personnel, and can receive dose data and nuclide concentration distribution data generated by simulation data, obtain monitoring data of the surrounding environment and transmit the monitoring data back to the master control module; the monitoring data at least comprise nuclide concentration and dose varying data. According to the invention, the simulation data generated by the nuclear accident evaluation system can be transmitted to the handheld monitoring module of an on-site exercise person in real time, and is dynamically displayed on the handheld monitoring module, so that the reality sense and interactivity of the exercise are enhanced.

The invention belongs to the field of CT (Computed Tomography) tomography reconstruction technology and artificial intelligence, and discloses a finite angle CT reconstruction artifact suppression method based on a multi-domain feature fusion network. In order to solve the problem that image quality and defect detection precision are affected due to the fact that a reconstruction result of traditional CT scanning is prone to artifacts and structural distortion under the condition of a limited angle, a multi-domain feature fusion artifact suppression network is constructed, and a limited angle reconstruction result is used as input. Through the synergistic effect of the encoder part, the decoder part, the feature enhancement part and the feature conversion part, artifact suppression and detail recovery are realized. According to the method, high-quality cross-sectional images can be obtained under the limited angle condition, the scanning angle and time of industrial CT detection are effectively reduced, the imaging definition and reliability are improved on the premise that the radiation dosage is not increased, and the method is suitable for industrial detection of workpieces of complex structures and has important industrial application value.

The invention discloses a capturing device of an inferior vena cava filter and a using method, and relates to the technical field of medical instruments. According to the capturing device of the inferior vena cava filter and the using method, the capturing device comprises a leading-in device, a snare catheter is movably installed in the leading-in device, a snare is movably installed in the snare catheter, a traction hook is movably installed in the leading-in device, and torque devices are installed on the surface of one end of the snare catheter and the surface of one end of the traction hook. According to the inferior vena cava filter, the traction hook provided with the inverted-U-shaped hook is additionally arranged, so that the operation space and angle are not limited, the inferior vena cava filter can be taken out only through one puncture point without assistance of other instruments, and the inferior vena cava filter is easy and convenient to operate, minimally invasive and safe; the operation time is obviously shortened, and the radiation dose of doctors and patients is reduced.

The application relates to a medical image acquisition method and device, computer equipment and a readable storage medium. The method comprises the following steps: acquiring a high-energy image of a detection object and low-energy images collected at different angles; based on the low-energy images, a tomographic sequence image is reconstructed; the tomographic sequence image and the low-energy images are subjected to a synthesis process to obtain a synthesis image; the synthesis image and the high-energy image are subjected to a subtraction process to obtain a subtraction image of the detection object. The method uses the synthesis image obtained from the reconstructed tomographic sequence image and the low-energy images to replace the low-energy images in the traditional subtraction, and the high-energy image is subjected to a subtraction process to obtain a subtraction image, so that the medical image required for the diagnosis of the detection object can be obtained on the basis of reducing the radiation dose of the patient.

The utility model relates to the field of waste polyester regeneration equipment, and discloses polyester micro-plastic impurity removal equipment. The equipment is used for realizing the impurity removal method and comprises irradiation treatment equipment, a separation tank, a cleaning tank, a dehydrator and a drying tower. The equipment is simple in structure and convenient to operate, can accurately control the radiation dose and time in the impurity removal process, effectively controls the surface temperature of the polyester micro-plastic, is easy to produce and popularize, and can be expanded and used according to different radiation methods.

The invention relates to the technical field of adjuvant therapy, and provides a radiotherapy tumor motion following system and method, which respectively controls the translational motion of a treatment bed and adjusts the motion parameters of an MLC blade based on a displacement vector from the acquisition of a respiratory motion signal and the inversion of the elastic modulus distribution of a target tissue to accurate displacement analysis. According to the following system, tumor motion compensation is obtained, all links are linked with one another, precise tracking and dynamic compensation of tumor motion are achieved, and compared with a traditional radiotherapy technology, the following system can remarkably improve radiotherapy precision, reduce radiotherapy errors caused by tumor motion and reduce the radiation dosage to surrounding normal tissues, and the radiotherapy precision is improved. And the problem caused by tumor movement in radiotherapy is solved from multiple dimensions.

This invention discloses an automatic bone densitometer localization method based on multimodal sensing and AI contour matching. The method uses a multimodal sensing module to collect data on the patient's three-dimensional contour, body thickness distribution, respiratory micro-movements, and dynamic displacement. After preprocessing and fusion to generate a feature map, an improved U-Net++ model and ICP registration algorithm are used to achieve precise segmentation and registration of the bone contour. Hardware-based collaborative calibration, dynamic tracking compensation, and error correction are then employed to achieve automated, high-precision localization of the target bone. This method reduces reliance on patient cooperation, achieves a localization accuracy of ≤0.3mm, a process time of ≤10 seconds, and low radiation dose. It is suitable for special populations such as the elderly, children, and those with scoliosis, as well as complex clinical scenarios, significantly improving the efficiency, accuracy, and safety of bone density testing.

The application provides an X-ray high-resolution image denoising method, an electronic device and a storage medium, comprising the following steps: obtaining a local diffusion model by retaining the first several steps of a diffusion model; constructing an iterative local diffusion framework based on the local diffusion model; loading a high-resolution to-be-processed degraded image dataset and a pre-trained local diffusion model; iteratively performing forward noise addition and reverse processes, and outputting a final denoising result. The application can meet the denoising needs of large-size and high-resolution detector data, thereby improving the quality of X-ray imaging; the application theoretically deduces an iterative local diffusion framework, uses a small amount of model resources to realize the representation of complex data, thereby developing an unsupervised denoising method which does not depend on labeled training data; and the iterative local diffusion denoising framework can reconstruct the details of lesions and tissues while reducing the radiation dose damage to patients by more than 75%.

The invention discloses a front movement collimation linkage control CT system and a control method.The CT system comprises an X-ray source, a front collimation assembly, a detector assembly, a patient support and a control unit, and the detector assembly is provided with a non-rectangular effective sensitive area and a non-sensitive area surrounding the effective sensitive area; the front collimation assembly comprises a Z-direction main blade and an X-direction auxiliary blade, the main blade is used for setting the isocenter coverage width, and the auxiliary blade is used for conducting fine cutting in an opening of the main blade; the patient support has X-direction preset positioning and mechanical locking functions; the control unit is configured to control the auxiliary blade in the scanning process, so that the projection boundary of the auxiliary blade on the detector is always located on the inner side of the non-sensitive area, and a preset safety belt is kept in the effective sensitive area. Through linkage control of conformal shielding of the non-rectangular detector, the X-direction auxiliary blade and X-direction preset positioning of the patient support, the imaging quality is guaranteed, and meanwhile the radiation dosage of the patient and invalid irradiation of the detector are remarkably reduced.

The application discloses a dual-resolution X-ray detector, the structure of the detector comprises from top to bottom in sequence: a packaging material, a fluorescent layer material, a first imaging surface, a second imaging surface and a control module; the pixel size of the first imaging surface is larger than the pixel size of the second imaging surface; the first imaging surface and the second imaging surface are tightly spliced to form a flat plate located at the same horizontal plane; further comprising an image processing module, the image processing module is electrically connected with the control module. The application can obtain two kinds of resolution images through one shooting by splicing two kinds of sensors with different resolutions, effectively reduces the shooting time, improves the diagnosis efficiency, reduces the radiation dose received by the patient, and protects the health of the patient.

The application discloses a stretchable organic X-ray photodetector based on a polymer semiconductor thin film, and particularly relates to a method for regulating and controlling self-assembly of a polymer blend thin film, and a high-sensitivity direct stretchable X-ray photodetector based on a polymer. The application proposes a strategy of eccentric spin coating for inducing self-assembly of a blend film, and a stretchable polymer thin film with nano confinement is prepared, and effective control of a nano morphology of a photoelectric material is realized. Based on the nano confinement thin film, the prepared stretchable X-ray photodetector not only has the X-ray detection capability of high sensitivity, fast response and low dose, but also has high light transmittance, high stretchability and fatigue resistance. Meanwhile, the application has unique advantages of low cost, large area and high flexibility, can be directly attached to a complex surface or structure of a living body, and thus high-definition detection results can be obtained in a lower radiation dose and a very short time, which has important significance in the fields of safety inspection and precision medical treatment.

A phantom system is disclosed that includes a phantom and at least one removable phantom attachment configured to be attached to the phantom so that the phantom system may have an orientation, location and / or anthropomorphic feature identifiable to an imaging device.

The invention discloses a time correction method and device, a computer storage medium and a digital PET system. The time correction method comprises the following steps: step S100, carrying out in-ring time correction on crystal strips of a plurality of detection rings in sequence to obtain in-ring time correction values of all the crystal strips; s200, all coincidence events between every two adjacent detection rings are obtained in sequence, and the single event arrival time of each coincidence event on the crystal strip is obtained; and S300, carrying out inter-ring time correction on the plurality of detection rings according to the position of the current to-be-calibrated ring, the in-ring time correction value and the peak value of the difference value of the arrival time of the two single events of each coincidence event. According to the invention, the overall time correction quality of the digital PET system can be improved, the image quality can be improved, the radiation dose can be reduced, and the inter-ring time correction of the long-axis PET can be realized at the cost as low as possible.

The utility model relates to the technical field of medical treatment, in particular to a breast cancer proton treatment body position fixing device which is detachably installed on a treatment bed and comprises a body bracket used for supporting the body of a patient and arranged on the treatment bed, and a headrest is installed on the body bracket; the angle adjusting mechanism is mounted on the treatment bed, connected with the body bracket and used for adjusting the placement angle of the body bracket relative to the treatment bed; the two arm brackets are symmetrically arranged on the two sides of the body bracket, the arm brackets are connected with multi-direction adjusting mechanisms installed at the side ends of the body bracket, and the multi-direction adjusting mechanisms are used for adjusting the vertical position and the horizontal position of the arm brackets. The arranged multi-direction adjusting mechanism can adjust the position of the arm bracket in the vertical direction and the horizontal direction, the distance between the arm of a patient and a mammary gland treatment area is adaptively increased, the path of a proton beam penetrating through the arm is remarkably reduced, and therefore the radiation dose received by the arm is reduced to the maximum extent.

The utility model discloses a radiotherapy equipment and radiation dose dynamic monitoring and alarm device, which is used for dynamically monitoring radiotherapy equipment and radiation dose in a radiotherapy process, and is characterized by comprising a sensor module, a main control module, a display module, an alarm module and a power supply module, the main control module comprises a control chip and a comparison circuit; the control chip is used for sending a control instruction to the sensor module, the main control module, the display module and the alarm module; the sensor module is electrically connected with the comparison circuit in a wireless or wired connection mode; the alarm module is electrically connected with the comparison circuit through the relay control circuit; the display module is electrically connected with the comparison circuit; and the power output end of the power module is electrically connected with each module. The radiotherapy equipment and the radiation dose dynamic monitoring and alarming device of the scheme integrate multi-parameter dynamic monitoring and dynamic alarming functions, and the whole process is realized through hardware, so that the response time is short, the system is reliable, and the failure rate is low.

Embodiments of the present disclosure provide a medical imaging device control method, device, equipment and medium. The medical imaging device includes a C-arm, and the method includes: acquiring a medical image of a human body part in real time through the C-arm; acquiring an initial three-dimensional model of the human body part from a preset model library; performing fusion processing on the initial three-dimensional model to obtain a target three-dimensional model, so that a projection image of the target three-dimensional model coincides with the medical image; updating a target position of the displayed target three-dimensional model based on a user operation instruction on the target three-dimensional model; and moving the C-arm to a target pose based on a conversion relationship between a coordinate system of the target three-dimensional model and a coordinate system of the medical imaging device, so that a medical image of the human body part acquired by the C-arm in the target pose coincides with a projection image of the target three-dimensional model in the target position. The present embodiment reduces the radiation dose received by the patient, reduces the degree of dependence on user experience, and improves operation efficiency.

In a method to determine a patient (radiation) dose distribution (13), it is provided to calculate, from a measured signal (7) of a detector (6) placed behind a region of interest, a dose distribution (11) for a patient-shaped water equivalent phantom (12) and to compute from this a patient dose distribution (13) that takes into account inhomogeneities of a matter distribution of the patient (4).

A method includes obtaining a base structure including a stack of dielectric layers disposed on a substrate. The stack of dielectric layers includes a first photosensitive dielectric layer including a first photosensitive dielectric material sensitive to a first radiation dose, a second photosensitive dielectric layer including a second photosensitive dielectric material sensitive to a second radiation dose different from the first radiation dose, and a barrier layer disposed between the first photosensitive dielectric layer and the second photosensitive dielectric layer. The method further includes forming a dual damascene structure from the base structure using a dual damascene process.