This invention discloses a method and
system for personalized radiotherapy planning of subtarget areas in gliomas. The method includes: inputting the target T1C image and its corresponding AAL image into a segmentation model to obtain a
brain region segmentation
mask file; inputting the target T1C image into a mapping model to obtain a pseudo-MRS image; inputting the target T1C image and the registered
glioma annotation file into a
habitat model to obtain a
habitat atlas; based on the
brain region segmentation
mask file, identifying whether the
habitat subregion is located in a functionally critical
brain region to determine whether its safe
dose threshold is set to the specific tolerable
dose corresponding to the functionally critical brain region; and determining the
radiation dose of the
glioma subregion based on the target T1C image, ASL, pseudo-MRS image, and safe dose threshold. This effectively improves the stability,
repeatability, and efficiency of target delineation and achieves biological conformity of
radiotherapy dose, thus providing an objective and accurate quantitative reference for developing radiotherapy plans.