The invention provides a medical intelligent medicine box system which comprises a lithium storage battery, a key power supply switch, a charging socket, a medicine box, medicine bottles, a weight detection circuit, a signal sending control circuit, a signal sending circuit, a timing circuit, a counting reminding circuit, an information receiving unit, an information comparison unit and an information pushing unit, wherein the information receiving unit, the information comparison unit and the information pushing unit are application software installed in mobile phones of doctors, patients andfamily members of the patients; the lithium storage battery, the key power supply switch, the charging socket, the quality detection circuit, the signal sending control circuit, the signal sending circuit, the timing circuit and the counting reminding circuit are arranged in the medicine box; and the medicine bottles are arranged in the medicine box. When the patient does not take medicine, reminding can be given to the patient in time; the treatment effect of the medicine taken by the patient is ensured; the doctor can favorably determine the treatment effect of a recipe; and after the medicine is out of date, the patient is reminded of not taking the medicine, so that the influence caused on body health when the patient innocently takes medicine which is out of date is avoided.