178results about How to "To achieve the purpose of sustained release" patented technology

The present invention discloses a carrier type slowly-released fertilizer and its preparation method. It not only has basic composition of general chemical fertilizer, but also contains carrier material, and its preparation method includes: firstly, dissolving carrier material with a certain quantity in water, then mixing general chemical fertilizer with it according to a certain proportion, uniformly stirring them to make them implement full reaction, adding cross-linking agent, making them implement further full reaction, removing water, finally pulverizing dried material and granulating.

The present invention relates to a chemical fertilizer and a manufacturing method thereof, specifically to a composite biological slow-release fertilizer product and its manufacturing method. Said composite biological slow-release fertilizer product in accordance with the present invention comprises granular fertilizer cores and coatings packing outside of the fertilizer cores, wherein said fertilizer cores are grains formed by a mixture of ternary compound fertilizer and the slow-release components which are mixture of urea and humic acids. Said coatings comprises at least animal oil and fat, bone meal and bacillus components. By replacing steam for heat spraying granulation with urea and humic acids melting complexing liquor, the manufacturing method in accordance with the present invention resolves the problem of moisture exceeding standard in 'three (organics, inorganics and bilogies) in one' fertilizer production and achieves the goal of nitrogen slow-release. At the same time, by adopting animal oil and fat and bone meal which can provide food such as lipids to animalcules and are easy to degrade as bacillus preparation carrier, said method overcomes the problems that the mixing of bacillus preparation and other fertilizer components leads to bacterial agent pollution and bacterium poisoning phenomenna. The present invention provides a 'three (organics, inorganics and bilogies) in one' composite biological slow-release fertilizer product which exhibits quick results, slow results and long results integrally, and a manufacturing method thereof.

The invention discloses high-performance recycled concrete and a preparation process thereof, and relates to the technical field of concrete preparation. The concrete includes the following raw materials in parts by weight: 220-240 parts of cement; 140-160 parts of fly ash; 60-80 parts of mineral powder; 600-800 parts of modified recycled coarse aggregate; 500-700 parts of natural gravel; 600-700parts of machined sand; 20-40 parts of a reinforcing agent; 40-60 parts of silicon powder; 4-8 parts of other additives; and 180-200 parts of water. By adjusting the ratio of the various raw materialsof the concrete, adding the reinforcing agent and modifying the recycled aggregate, the working performance of the concrete can be effectively improved, and the compactness and overall strength of the concrete can be improved.

The invention relates to a production technology for preparing recycled aggregate from waste concrete. The technology comprises the following steps: S1, preprocessing: carrying out jet wetting and epidemic prevention treatment on waste concrete blocks, and then hammering the waste concrete blocks to make the diameter of the hammered concrete blocks less than 50 mm; S2, screening: screening the preprocessed material obtained in step S1; S3, crushing: crushing the screened waste concrete blocks obtained in step S2 to prepare recycled aggregate; S4, reinforcing: reinforcing the recycled aggregateobtained in step S3; and S5, conveying the reinforced recycled aggregate to a storage bin for storage. The recycled aggregate is prepared by preprocessing, screening, crushing, reinforcing, drying and collecting the waste concrete, so that the effective utilization of the waste concrete is realized, the waste of resources is reduced, and the utilization rate of energy is increased.

The invention relates to a tilmicosin micro-capsule preparation, and in particular relates to a tilmicosin micro-capsule preparation and a preparation method of the tilmicosin micro-capsule preparation, belonging to the technical field of veterinary medicine. The tilmicosin micro-capsule preparation comprises an inner core layer and a coating layer, wherein the inner core layer comprises a tilmicosin raw material and macromolecule auxiliary materials, the macromolecule auxiliary materials are selected from one or more than one of 12-carbon fatty acid-18-carbon fatty acid, paraffins and vegetable wax; and the coating layer comprises an inner coating layer and an outer coating layer, wherein the material of the inner coating layer is one or more than one of starch, calcium carbonate and calcium hydrophosphate, and the material of the outer coating layer is acrylic resin. The tilmicosin micro-capsule preparation disclosed by the invention is tasteless, enteric, and good in palatability. According to the invention, the tilmicosin is packed by the macromolecule auxiliary materials, a layer of enteric coating layer is sprayed on the surfaces of the tilmicosin grains in the process of rolling circle when the materials are prepared, and the strong bitter taste and odor of the tilmicosin can be completely covered due to the double-layer package, and the preparation method is simple in technology, and low in cost.

The invention provides a PCLm-PEG6000-PCLm thermo-sensitive self-assembled tri-block copolymer, wherein the copolymer presents two-phase transition characteristics, and can be applied to a controlled release drug delivery system as a drug carrier or can be applied to tissue engineering as a biodegradable material. The invention further provides a pharmaceutical composition containing the tri-block copolymer, and a preparation method and an application of the pharmaceutical composition. A system consisting of PCLm-PEG6000-PCLm tri-block copolymer and water can both load water-soluble drugs, and can efficiently load water-insoluble drugs, and has an excellent controlled-release effect.

The invention discloses sodium iron chlorophyllin-chitosan/sodium alginate microcapsules and a preparation method thereof. In the method, chitosan/sodium alginate is used as a capsule material, sodium iron chlorophyllin is used as capsule content, and the sodium iron (II) chlorophyllin is microencapsulated by an emulsification-gel method. The preparation method comprises: dissolving sodium iron chlorophyllin in sodium alginate solution at a certain concentration, adding the prepared solution in vegetable oil containing Span-60, and stirring at high steep and emulsifying for 20 minutes; dripping acetic acid aqueous solution containing 2.0-percent chitosan and calcium chloride, continuously stirring for 30 minutes, standing for 2 hours and removing an oil phase; and washing the microcapsules with petroleum ether and isopropanol for three times respectively, performing suction-filtration, and drying at room temperature to obtain the sodium iron chlorophyllin-chitosan/sodium alginate microcapsules. The chitosan which is a natural polysaccharide with high biocompatibility and biodegradability and the sodium alginate serve as sustained and controlled release agent and targeting preparation, the sodium iron chlorophyllin is encapsulated in the center of the microcapsules to be protected from instability caused by change in a light or placing condition, a new formulation is provided in pharmacy, and the microcapsules are suitable to be further developed and used as iron-supplying health-care food and new medicinal preparation for treating iron-deficiency anemia, and have a bright application prospect.

The invention discloses Litsea cubeba essence oil clathrate and a preparation method of the Litsea cubeba essence oil clathrate. The method comprises the following steps: (1) preparing beta-cyclodextrin (beta-CD) saturated aqueous solution at a controlled temperature of 40-80 DEG C, stirring until smooth, and adding Tween 20 until the volume fraction of Tween 20 in beta-CD aqueous solution is 0.1%-0.5% to obtain Tween 20-containing beta-CD saturated aqueous solution; (2) adding Litsea cubeba essence oil into a solvent at volume ratio of 1:(1-4) to obtain Litsea cubeba essence oil solution; and (3) dropping Litsea cubeba essence oil solution into Tween 20-containing beta-CD saturated aqueous solution according to a ratio of 1:(8-12) mL/g of Litsea cubeba essence oil to beta-CD, stirring for 3-5 h at 40-80 DEG C, standing for 12-48 h at 0-4 DEG C for precipitation, filtering, collecting precipitate, washing, and freeze-drying to obtain Litsea cubeba essence oil clathrate. The clathrate can slowly release active ingredients of Litsea cubeba essence oil, has lasting effects in resisting mildew/bacteria and refreshing air, and is convenient to carry and use.

The invention discloses an antifouling polyurethane coating. The antifouling polyurethane coating comprises the raw materials of perfluoroalkyl ethyl alcohol, polytetrahydrofuran ether glycol, polycarbonate diol, diphenylmethane diisocyanate, isophorone diisocyanate, 1,4-butanediol, stannous octoate, stannous oleate, amino silane, nano titanium dioxide, nano zinc oxide, nano calcium carbonate, nano ferric oxide, talc powder, a modified antifouling agent, a dispersant, ethyl cellulose, a leveling agent, propylene glycol, a film forming assistant, and deionized water. The antifouling polyurethane coating disclosed by the invention, is strong in adhesive force with a substrate, excellent in antifouling performance, and good in heat resistance, weather resistance and water resistance.

The invention belongs to the technical field of environmental protection, and particularly relates to a preparation method of a slow-release potassium ferrate water treatment agent. The invention aims to provide a potassium ferrate water treatment agent with slow-release effect. The preparation method provided by the technical scheme comprises the following steps: dissolving calcium hypochlorite in a saturated potassium hydroxide solution, adding iron nitrate nonahydrate, stirring, adding kieselguhr, carrying out ice segregation, standing, and carrying out vacuum filtration, wherein the filter cake is the slow-release potassium ferrate water treatment agent. The slow-release potassium ferrate water treatment agent provided by the invention can implement slow release of potassium ferrate in a water treatment process, lower the noneffective decomposition of the potassium ferrate, and enhance the utilization effectiveness of the potassium ferrate, thereby achieving the goals of lowering the reagent consumption and enhancing the water treatment effect.

The invention relates to a chlorine dioxide slow-release device and its replenishment liquid, in particular to a chlorine dioxide slow-release device and its replenishment liquid for epidemic prevention and disinfection, food antisepsis and air purification. The device includes three parts: a container, a container cover, and a strip-shaped volatile matter. The supplement liquid includes the following parts by weight: 1-15 parts of sodium chlorite, 1-15 parts of activator, 1-10 parts of thickener, 1-5 parts of stabilizer, 0.5-2 parts of air barrier agent, 53-5 parts of purified water 95.5 servings. The beneficial effect of the device is to stably preserve the activated chlorine dioxide liquid, and to control the amount of moisture and air in contact with the strip-shaped volatiles by increasing and/or reducing the total area exposed to the strip-shaped volatiles in the air. Control the amount of chlorine dioxide released. According to the scale prompt on the container, when the chlorine dioxide liquid drops to a certain level, open the container cover, add replenishing liquid, and it can be recycled. It has the advantages of simple preparation process, low cost, convenient use and environmental protection.

The invention discloses a preparation method for carbon-coated ferroferric oxide nano-shell-loaded nano gold particles. The method is capable of, according to an Ostwald ripening theory, and through aferroferric oxide nano-shell prepared by using a soft template method in advance, using glucose as a carbon source and performing hydrothermal coating, finally loading nanogold by using a chemical reduction method. The obtained ferroferric oxide nano-shell is a carbon-coated ferroferric oxide hollow-core nano-shell. Compared with a solid nano-shell, the carbon-coated ferroferric oxide hollow-corenano-shell is large in specific surface area, and high in drug loading ratio. On the other hand, a shell structure is capable of controlling burst release of a drug so as to achieve a purpose of slowrelease.

The invention discloses a preparation method of peppermint oil microcapsules. The preparation method comprises steps as follows: ethanol and tween-80 are mixed, and a carrier solution is obtained; peppermint oil is added to the carrier solvent and dissolved, and a core material I is obtained after uniform stirring and mixing; the core material I is added to a hydroxypropyl beta cyclodextrin solution and uniformly stirred, and a core material II is obtained; the core material II is added to a gelatin solution and has a sufficient reaction, and an Arabic gum solution is added; the systematic solution is adjusted to be acidic, formaldehyde is added for cross-linking and curing after rapid cooling, and the pH (potential of hydrogen) value is adjusted until the mixture is alkaline; the mixture is left to stand until complete precipitation and washed to be neutral with water after filtering, and a product is obtained after vacuum drying. The preparation method has the advantages that the embedding rate of the prepared microcapsule can be up to 90% or higher, the method is simple, effective ingredients of a cooling agent don't easily volatilize and the like.

The invention provides calophyllum inophyllum kernel oil included lecithin liposome having a core-shell structure. A core of the liposome is composed of calophyllum inophyllum kernel oil, a shell thereof is composed of lecithin, and the liposome is 19.99-72.70 nm in average particle size and 30-50% in inclusion rate. Further provided is a preparation method of the calophyllum inophyllum kernel oil included lecithin liposome and application of the calophyllum inophyllum kernel oil included lecithin liposome in soothing scar-fading products, the calophyllum inophyllum kernel oil included lecithin liposome has a percent-by-mass concentration of 30-50% in a soothing scar-fading product, and the soothing scar-fading product is scar cream, scar milk or scar gel. The liposome of the invention not only has better stability of the included active ingredient, calophyllum inophyllum kernel oil, but also can release slowly; meanwhile, the calophyllum inophyllum kernel oil included lecithin liposome has good scar-fading effect in the soothing scar-fading product.

The invention discloses an oral slow release preparation, an entrapment material and a preparation method. A sodium alginate-sodium hyaluronate mixture is taken as an entrapment material; and a prepared protein polypeptide medicament oral slow release preparation consists of the following components in percentage by mass: 0.5-10 percent of medicament and 90-99.5 percent of sodium alginate-sodium hyaluronate mixture. According to the oral slow release preparation, the conventional administration way of a protein polypeptide medicament is changed, the acting time of the protein polypeptide medicament is prolonged, the normal blood sugar level is maintained successfully for 12 hours when exenatide oral microspheres are taken as an example, the administration compliance of a diabetes patient is improved remarkably, and the treatment effect is enhanced.