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3results about How to "Achieve slow release" patented technology

A drug-loaded porous magnesium alloy bone scaffold and its preparation method

ActiveCN120733114Bachieve slow releasefirmly attachedTissue regenerationCoatingsMg alloysTissue Compatibility
This invention belongs to the field of medical materials technology, specifically referring to a drug-loaded porous magnesium alloy bone scaffold and its preparation method. The drug-loaded porous magnesium alloy bone scaffold is composed of the following raw materials in parts by weight: 55 parts magnesium alloy, 6-10 parts corrosion inhibitor, 1 part drug-loaded gel, 2-4 parts antibacterial bone-promoting agent, and 3 parts gelatin. This invention achieves sustained drug release by fabricating magnesium alloy into microtubes and filling the interior with a drug-loaded hydrogel; gelatin is sprayed onto the surface and adhered through Mg-N coordination bonds, bonded to the corrosion inhibitor, and hot-pressed. The components form an interpenetrating network with the gelatin to enhance bonding and react with the magnesium alloy to form a protective film; simultaneously, Ca... 2+ The process initiates cross-linking of sodium alginate, forming a stable anti-corrosion barrier. Finally, an antibacterial and bone-promoting mixture containing modified chitosan and thermosensitive polymer is sprayed on. Through complexation reaction and temperature control, the bone-promoting components are evenly dispersed around the implant, improving tissue compatibility.
Owner:CHANGDE FIRST PEOPLES HOSPITAL

Sports shoes with wide soles

ActiveCN224386864Uachieve slow releaseAvoid sudden release wasteSolesExercise stressStructural engineering
The utility model relates to a kind of sneakers of wide type shoe sole, including upper and shoe sole, and the palm part and heel of shoe sole are equipped with damping device in, the damping device includes base and shell, the base is equipped with recess, the recess is filled with medicament material, and the top wall of accommodating cavity and recess gap are left gap accommodating cavity is filled with slow-release material, conveying channel is equipped in the shell outer wall and is spirally coiled along its axial direction, shoe sole upper surface is equipped with spiral guide slot, and accommodating cavity is connected guide slot by conveying channel. The recess of the utility model is filled with antibacterial deodorization medicament, medicament is covered with slow-release material, conveying channel is spirally coiled in shell outer wall, and slow-release material and conveying channel are cooperated to form double restraint, realize the slow-release of traditional chinese medicine effective component, avoid component sudden release waste under exercise pressure, significantly prolong antibacterial deodorization effective period.
Owner:QUANZHOU PENGCHENG SHOES CO LTD

A method for preparing a fine coffee extract in a microcapsule structure, the extract and its use

PendingCN122256074Aavoid volatile lossReduce direct violent reactionsEssential-oils/perfumesMicroballoon preparationEmulsionMedicine
This invention discloses a method for preparing a microcapsule-structured specialty coffee extract, the extract itself, and its applications, belonging to the field of fragrance and flavor technology. The method includes: adding an emulsifier to the specialty coffee extract and emulsifying it at 1530°C to obtain an emulsion; preheating a melamine resin prepolymer to 4045°C and adding it to the emulsion; raising the temperature to 4550°C within 15 minutes and adjusting the pH to 4.5-5.5 for the first stage reaction; then raising the temperature to 6080°C for the second stage reaction; and finally cooling and adjusting the pH to 7.5-8.5 to terminate the reaction, thus obtaining the microcapsule-structured specialty coffee extract. This invention, through room-temperature emulsification and a two-stage temperature-controlled process, effectively preserves the complex aroma of the specialty coffee extract. The resulting microcapsule structure is dense and stable, possessing both sustained-release and rapid aroma release via friction, significantly extending the aroma retention time. This invention also provides the application of the microcapsule-structured specialty coffee extract in the preparation of pet products.
Owner:GUANGZHOU BAIHUA FLAVOURS & FRAGRANCES CO LTD