The present invention provides a thickener for solving a problem of difficulty in swallowing and a preparation method of the thickener. The thickener is prepared from xanthan gum, maltodextrin, aloe vera extract freeze-dried powder, agar, edible gelatin, a pH value regulator, chitosan oligosaccharide, guar gum and potassium chloride as raw materials. All the raw materials are natural thickeners. Besides, the components completely cover animal thickeners, plant thickeners, microbial thickeners and enzyme treatment thickeners. The thickener for solving a problem of difficulty in swallowing is prepared by mixing, homogenizing and spray-drying, dissolvability is improved, and mouthfeel and a taking effect are improved. The thickener is added into liquid food, full stirring is conducted to enable food to be thicker and smoother, and water is prevented from choking the lungs. The thickener for solving problem of difficulty in swallowing has great help for people with dysphagia, such as infants, old people, patients and the like, and can eliminate esophageal edema, reduce inflammatory risks and repair esophageal cells.