602results about How to "High embedding rate" patented technology

The invention provides a method for preparing composite microspheres with the particle diameter of 0.01-100Mum and adjustable particle size distribution. The method is characterized in that one or more kinds of superfine particles is added to two or more kinds of polymer (or performed polymer) with fluxible processability to form composite microspheres by reaction mixing and oriented dispersion technique of superfine particles. The composite micropheres have the advantages of even dispersion of superfine particles and large embedding amount. The preparation method has the advantages of continuous preparation and low cost, and has wide application prospect in fields such as biological medical treatment, electronic message, daily life, etc.

The invention relates to the technical field of the food additive and the microcapsule equipment capable of controlling the release of bioactive substances, in particular to a preparation method of menthol microcapsules. The preparation method uses menthol, wall material, emulsifier, crosslinking agent, pH regulator and water as the raw materials, wherein menthol is used as the core material, chitosan is used as the wall material, monoglyceride and Tween-40 are used as the compound emulsifier, 10% acetic acid is used as the pH regulator. The preparation method comprises the following steps: emusifying the solution under high pressure, adding modified starch to crosslink, finally adopting the spray drying technology to prepare the powdery menthol microcapsule product. The invention aims to provide a menthol microcapsule preparation method with safe and easy technology and low cost, increase the stability and heat resistance of menthol, control the release process and expand the application range.

The invention discloses a macromolecular microcarrier and a preparation method thereof, belonging to the technical field of biomedicine. The preparation method comprises the following steps of: splitting a silk solution and a drug solution into micrometer grade liquid drops with core-shell structures under the action of a high-voltage electric field by adopting a coaxial high-voltage electrostatic technology and a freeze drying method; concreting through liquid nitrogen, and then preparing the microcarrier which is difficult to dissolve in water through freeze drying. The microcarrier is in the shape of a microsphere with the core-shell structure, and the diameter of the microsphere is 100-500 micrometers; the shell of the microcarrier comprises the components of silk fibroin; the random-coil conformation of silk fibroin molecules is 80-90 percent; the shell is in a porous structure, and an aperture is 5-20 micrometers; and a core of the microcarrier comprises the components of water-soluble drugs. The silk microcarrier has extensive application prospect in the fields of cell culture, drug release, and the like.

The invention discloses a beta-carotene microcapsule production method. The method comprises the following steps: performing on-line mixing an oil phase containing beta-carotene, an anti-oxidant and plant oil and a water phase containing a capsule material, the anti-oxidant, a dispersant and water, homogenizing, and performing spray drying to obtain the beta-carotene microcapsule powder. Due to on-line mixing in proportion, a lot of production time is saved, production efficiency is increased, large scale industrial production is convenient, and the beta-carotene microcapsule has the advantages of high homogeneity, high encapsulation efficiency and high stability.

The invention belongs to the technical field of oil processing, and particularly relates to a preparation method of saccharose-free functional powdered peony seed oil. The method comprises the following steps: (1) dissolving wall materials with distilled water, and heating and stirring to obtain a solution A; (2) adding food functional factors and an emulsifier into peony seed oil, and mixing and stirring uniformly to obtain an emulsion; (3) shearing and emulsifying the emulsion obtained in the step (2) to obtain an emulsion solution; (4) adding the solution A obtained in the step (3) into the emulsion solution obtained in the step (3), and homogenizing at high pressure to obtain a solution B; and (5) spray-drying the solution B obtained in the step (4), thereby obtaining the powdered peony seed oil. The powdered peony seed oil prepared by the method can be compounded with different nutritive substances according to demands of different groups of special people; as the peony seed oil is high in content of alpha-linolenic acid, the powdered peony seed oil is high in nutritive value; and due to containing no saccharose, the powdered peony seed oil is suitable for patients with hyperglycemia and diabetes to take.

The invention discloses a kernel-shell structural nanofiber membrane, a preparation method thereof and an application; the preparation method includes steps of (1), preparation of spinning; dissolving sodium alginate, polyoxyethylene and poloxamer F127 in distilled water, stirring evenly and acquiring shell layer spinning solution; mixing the chitosan nanoparticle solution loaded with active matters with polyving akohol solution evenly, and acquiring the kernel layer spinning solution; (2), coaxial electrostatic spinning: respectively injecting the shell layer spinning fluid and kernel layer spinning fluid in a static spinning device containing a coaxial needle, performing the coaxial electrostatic spinning under room temperature, performing solvent evaporation in the spinning process, and acquiring the kernel-shell structural nanofiber membrane loaded with the nanoparticle. The preparation method is simple in operation and gentle in reaction condition and can well control the slow release of the active matter; moreover, the prepared colon targeting controlled release system has obvious colon targeting property, thereby improving the utilization degree of the active matter. The colon targeting controlled release system can be applied to functional food domain.

The invention relates to peony seed oil microcapsule powder. The yeast peony seed oil microcapsules are prepared from peony seed oil serving as a raw material and a yeast wall material by using a yeast microcapsule method or are prepared by emulsification, encapsulation, solidifying and drying of a complex coacervation capsule method. The produced peony seed oil microcapsules can be applied to solid beverages such as milky tea and coffee, are capable of improving the instant solubility of products and intensifying nutrition of the products and can also be directly applied to health products, cosmetics and food. Chemical solvents are not added in a peony seed oil microcapsule preparation process, so that the peony seed oil microcapsules are green, environment-friendly and beneficial to the physical health of eaters; the relatively low temperature is always maintained in the whole process, so that the activity of functional components in the peony seed oil can be kept to the maximum degree.

The invention belongs to the technical field of natural product microcapsules and discloses natural carotene microencapsulated powder and a preparation method thereof. The natural carotene microencapsulated powder is prepared from the following components in parts by weight: 5 to 15 parts of a core material, 20 to 80 parts of a wall material, 0.1 to 2 parts of an oil-phase antioxidant, 0.1 to 5 parts of a water-phase antioxidant, 0.1 to 7 parts of an emulsifier, 0.1 to 2 parts of a thickener, 0.1 to 2 parts of an acidity regulator and 30 to 140 parts of a dispersant, wherein the core material is natural carotene oil suspension liquid; the wall material is selected from one or more of starch sodium octenyl succinate, Arabic gum and porous starch; the dispersant is selected from one or more of maltodextrin, sucrose and starch syrup. By regulating a formula and a spraying process, the natural carotene microencapsulated powder which has a high encapsulation rate, can be dissolved in cold water and has good stability is prepared.

The invention relates to a probiotics microcapsule product. The probiotics microcapsule product is a spherical or irregular microcapsule with grain size of 10 to 1,000 microns and has a structure being divided into two parts, namely, a wall layer and an inner core, wherein the wall layer is composed of alginate, chitosan and a methacrylic acid-methacrylate high polymer material; and the inner core is high-density probiotics.

The invention relates to a spray freeze-drying preparation technology for a polyunsaturated fatty acid oil microcapsule, which comprises the following technological steps: mixing oil containing polyunsaturated fatty acid with emulsifier and water to obtain mixture; homogenizing the mixture to obtain emulsion; atomizing the emulsion into liquid drops which are sprayed into a spray drying device with temperature of negative 60 DEG C to negative 10 DEG C, wherein powder embedding materials are contained at the bottom part of the spray drying device, and blasting low-temperature gas to fully mix the materials in the spray drying device and to keep the temperature in the spray drying device to be the set temperature; and further drying and screening to obtain polyunsaturated fatty acid oil microcapsule products. The invention has the advantages that the drying temperature of the preparation technology is low, the speed is fast and the nutritional ingredients are not apt to be damaged; the technology is simple and convenient and the automatic mass production can be realized; and the oil embedding rate of the obtained independent polyunsaturated fatty acid oil microcapsule particles is high, the embedding performance is good, the product shelf life is long and the stability is good.

The invention discloses a method for preparing a melissa officinalis L. essential oil and beta-cyclodextrin molecule microcapsule and aims to improve the physical and chemical properties and the stability of the melissa officinalis L. essential oil and expand the application range of the melissa officinalis L. essential oil. The method comprises the following steps of: adding ethanol solution of the melissa officinalis L. essential oil into saturated aqueous solution of beta-cyclodextrin slowly, wherein the molar ratio of citral in the melissa officinalis L. essential oil to beta-cyclodextrin is 1:2, and the volume ratio of the melissa officinalis L. essential oil to ethanol is 3:100; oscillating the solutions for 3 hours at a rotating speed of 160r/min at the temperature of 30 DEGC for complete reaction, preserving a product of reaction at the temperature of 4 DEG C for 4 hours, standing, and precipitating; and filtering the obtained solution, and drying a precipitate at the temperature of 50-70 DEG C for 4 hours to obtain the melissa officinalis L. essential oil and beta-cyclodextrin molecule microcapsule. By encapsulating beta-cyclodextrin and the melissa officinalis L. essential oil, the powder of the molecule microcapsule has extremely good optical and thermal stability; the range of application of the melissa officinalis L. essential oil is expanded; and the method is simple and highly practical.

The invention relates to an acid-proof type microalgae DHA oil microcapsule powder and a preparation method thereof. The acid-proof type microalgae DHA oil microcapsule powder is prepared from 12.6%-30.3% of core materials and 69.7%-87.4% of wall materials, concretely comprising the following active ingredients in percentage by weight: 12.5%-30.0% of microalgae DHA oil, 0.1%-0.3% of antioxidant, 25.0%-50.0% of whey protein, 3.0%-8.0% of food emulsifier, 20.0%-54.4% of sweetener, 4.40%-8.0% of hydrophilic colloid, and 0.60%-1.20% of acidity regulator. The prepared acid-proof type microalgae DHA oil microcapsule powder has good acid-proof property, and can be applied in a food system of an acid water system with pH of more than or equal to 3.5, the oxidization speed of microalgae DHA can be effectively reduced and delayed, the activity of the microalgae DHA can be maintained, the stability of microalgae DHA in acid water system food can be enhanced, and the shelf life of the acid water system food with microalgae DHA can be prolonged.

The invention relates to a method for preparing a small molecule hydrophilic drug-embedded sustained-release capsule. The method comprises the following steps: filtering a prepared'internal aqueous phase/oil phase/external aqueous phase' pre-multi-emulsion solution through a microporous membrane; and then removing a solvent, washing and drying to obtain the small molecule hydrophilic drug-embedded sustained-release capsule, wherein the internal aqueous phase comprises a small molecule hydrophilic drug and a thickening agent. The small molecule hydrophilic drug-embedded sustained-release capsule provided by the invention has the advantages of uniform grain diameter, high embedding rate, low burst-release rate, stable drug release and long action.

The invention provides a method for acknowledging an IP core copyright by a digital watermarking technology. The method has the advantages of low cost, high universality, high compatibility, high feasibility and fully integrated automation. The technical scheme is that the method is characterized by comprising a watermark embedding step and a watermark extracting step. The watermark embedding steps comprises the following procedures: first, selecting a coordinate of an initial watermark point in a layout, and processing copyright information by a one-way Hash function to obtain an offset of the watermark point coordinate, and obtaining the scattered watermark point coordinate pseudo-randomly distributed in the layout; and then normalizing the attribute of the selected watermark point to embed the special watermark representing the copyright information; and finally, successfully embedding the watermark information for the watermark point which is not normalized by the two methods by repeated diffusion, judgment and additional means, thus obtaining a layout data file with the watermark information. The watermark extracting step comprises the following procedures: obtaining the pseudo-randomly scattered watermark point coordinate by the method similar to the watermark embedding step based on record files of the watermark embedding information, thus recovering the watermark point coordinate successfully embedded finally and then judging whether the watermark point successfully embedded finally coincides with a polysilicon layer in the layout and outputting a watermark extraction report.

The invention discloses a natural volatile solid fresh-keeping agent for fruit and vegetables and a preparation method thereof. The fresh-keeping agent is prepared by mixing main raw material and adjuvants at a certain ratio in parts by weight, and taking rice flour and maltodextrin as a wall materials and essential oil mixed with natural spices as a core material; ingredients of the main raw material are rice flour, maltodextrin and essential oil mixed with natural spices, and the adjuvants comprise an antiseptic, an adhesive, a crisp-keeping agent, an emulsifier and an ethylene receptor inhibitor. The natural volatile solid fresh-keeping agent for fruit and vegetables has the main advantages of realizing freshness keeping of fruit and vegetables by volatilizing the essential oil mixed with natural spices and 1-MCP which respectively contact surfaces of fruit and vegetables; employing microcapsule technology to embed the essential oil mixed with natural spices and the 1-MCP to effectively control volatilization rate of the essential oil mixed with natural spices and the 1-MCP, improve utilization rate of effective ingredients and solve freshness-keeping technical problems of fruit and vegetables in the course of transport; and the product made from natural materials is safe and nontoxic. See the accompanying drawings of the abstract for processing technology of the fresh-keeping agent.

In order to solve the problems that the granules are non-uniform, the surface is provided with cracks and recesses and the compactness of the microcapsule wall is low in the conventional microcapsule product and the product is low in thermal solubility, low in emulsifying property and high in sugar content and has the soybean smell, the invention provides a walnut oil microcapsule and a preparation method thereof belonging to the technical field of oil microencapsulation. The walnut oil microcapsule is prepared by taking 15-25 parts of walnut oil, 0.6-3.4 part of sucrose ester and 1.5-3.2 parts of monoglyceride as the core material and taking 3-10 parts of cane sugar, 18.3-27.6 parts of maltodextrin, 17.6-28.3 parts of peanut protein isolate and 1.3-3.5 parts of dipotassium phosphate as the wall material. Therefore, the prepared walnut oil microcapsule has the advantages of smooth surface, uniform particle size and high compactness of microcapsule wall.

The invention provides a seaweed ferment probiotic microcapsule and a preparation method thereof. The microcapsule comprises a microcapsule wall, a microcapsule core material and a core material carrier, wherein the microcapsule wall is prepared from sodium alginate, chitosan and calcium chloride, the microcapsule core material is prepared from seaweed ferment and probiotic, and the core materialcarrier is corn starch. The seaweed ferment probiotic microcapsule of the invention can effectively block the influence of gastric acid and the like on the viable bacteria number and activity of the probiotic, so that the seaweed ferment and probiotic act on the intestinal micro-ecological environment together, and the unique biological effect is achieved. The preparation method is simple in process, is relatively low in cost, and is easy to store and transport. Compared with other probiotic products, the microcapsule has the advantages of good film-forming property, strong stability, high probiotic survival rate, good slow release efficiency and the like, is suitable for embedding and controllable release of various probiotics, and has good application prospects.