Calophyllum inophyllum kernel oil included lecithin liposome and application thereof in soothing scar-fading products

A lecithin and liposome technology, which is applied in the field of daily chemicals, can solve the problems of poor slow-release effect and poor effect of daily chemicals on smoothing and scarring.

Active Publication Date: 2016-06-15
上海京樾医疗科技有限公司
View PDF2 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the above-mentioned technical problems in the prior art, the present invention provides a lecithin liposome embedded with crabapple fruit oil and its application in smoothing and scar-reducing products. Phospholipid liposomes

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Calophyllum inophyllum kernel oil included lecithin liposome and application thereof in soothing scar-fading products
  • Calophyllum inophyllum kernel oil included lecithin liposome and application thereof in soothing scar-fading products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0130] A lecithin liposome embedding crabapple fruit oil is prepared by the following method:

[0131] (1), 3.0g glyceryl caprylate, 2.5g blue light nanoemulsifier, 4.0g solubilizer, 1.0g glycerol monostearate, 4.0g glycerin, 0.05g antioxidant 2,6-di-tert-butyl Put hydroxytoluene, 0.3g of preservatives, namely 0.2g of methylparaben and 0.1g of propylparaben into a beaker, heat and stir in a water bath at about 60°C until completely dissolved to obtain a liquid oil phase;

[0132] (2) After cooling down, add 3.5g of crabapple oil and 3.0g of lecithin into the above liquid oil phase, heat and stir at low temperature until completely dissolved to obtain a homogeneous system;

[0133] (3), 78.65g of deionized water is used as the water phase, and the obtained homogeneous system is the same as water, and the water bath is heated to the emulsification temperature;

[0134] (4) Take the homogenizer, add the homogeneous system obtained in step (3) into the water phase obtained in ste...

Embodiment 2

[0136] A lecithin liposome embedding crabapple fruit oil is prepared by the following method:

[0137] (1), 4.0g glyceryl caprylate, 3.0g blue light nanoemulsifier, 5.0g solubilizer, 1.0g glycerol monostearate, 5.0g glycerin, 0.05g antioxidant 2,6-di-tert-butyl Put hydroxytoluene, 0.3g of preservatives, namely 0.2g of methylparaben and 0.1g of propylparaben into a beaker, heat and stir in a water bath at about 60°C until completely dissolved to obtain a liquid oil phase;

[0138] (2) After cooling down, add 5.0g of crabapple fruit oil and 4.0g of lecithin into the above liquid oil phase, heat and stir at low temperature until completely dissolved to obtain a homogeneous system;

[0139] (3), 72.65g of deionized water is used as the water phase, and the obtained homogeneous system is the same as water, and the water bath is heated to the emulsification temperature;

[0140] (4) Take the homogenizer, add the homogeneous system obtained in step (3) into the water phase obtained ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
The average particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention provides calophyllum inophyllum kernel oil included lecithin liposome having a core-shell structure. A core of the liposome is composed of calophyllum inophyllum kernel oil, a shell thereof is composed of lecithin, and the liposome is 19.99-72.70 nm in average particle size and 30-50% in inclusion rate. Further provided is a preparation method of the calophyllum inophyllum kernel oil included lecithin liposome and application of the calophyllum inophyllum kernel oil included lecithin liposome in soothing scar-fading products, the calophyllum inophyllum kernel oil included lecithin liposome has a percent-by-mass concentration of 30-50% in a soothing scar-fading product, and the soothing scar-fading product is scar cream, scar milk or scar gel. The liposome of the invention not only has better stability of the included active ingredient, calophyllum inophyllum kernel oil, but also can release slowly; meanwhile, the calophyllum inophyllum kernel oil included lecithin liposome has good scar-fading effect in the soothing scar-fading product.

Description

technical field [0001] The invention belongs to the field of daily chemicals and relates to a liposome, specifically a lecithin liposome embedded with crabapple fruit oil and its application in products for calming and reducing scars. Background technique [0002] Scar, also known as scar, is a general term for the appearance and histopathological changes of normal skin tissue caused by various traumas. It is an inevitable product in the process of human trauma repair. However, the existence of scars will not only affect people's external image, but also sometimes cause various complications, bringing people great physical pain and mental torture, so it is very important to calm down the scars. [0003] Crabapple fruit oil is extracted from the nuts of the crabapple tree in Indonesia and is certified as an organic vegetable oil by ECOCERT. This native vegetable oil is rich in biological activity, contains a variety of fatty acids and fat accompanying substances (resins and ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/14A61K8/55A61K8/92A61Q19/02
CPCA61K8/14A61K8/553A61K8/922A61Q19/02
Inventor 章苏宁周艳
Owner 上海京樾医疗科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap