The invention discloses a traditional Chinese medicine preparation for treating breast cancer and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following main crude drugs in parts by mass: 13-20 parts of radix paeoniae alba, 2-4 parts of Indian iphigenia bulbs, 10-16 parts of ligotidis herba, 12-18 parts of raphani leaves, 8-13 parts of drymoglossum piloselloides, 7-12 parts of tangerine leaves, 15-20 parts of peperomia blanda, 16-25 parts of trichosanthes kirilowii, 11-19 parts of scabrousstem greenbrier rhizome, 14-20 parts of cottonrose hibiscus, 11-16 parts of four-leaf clovers, 6-14 parts of snake slough, 9-14 parts of adiantum capillus veneris and 10-17 parts of bittersweet herbs. The traditional Chinese medicine preparation is remarkable in curative effect, free of side effects, free of damage to an organism, capable of relieving the pain of a patient, prolonging the lifetime of the patient and improving the life quality of the patient, low in treatment cost, available in drug resource and low in price, and is easily accepted by the patient.