713 results about "Conjugated linoleic acid" patented technology

Methods and compositions for the prevention, therapy and / or treatment of several disease states. The methods comprise the administration of a therapeutically effective amount of a composition including krill extract and conjugated linoleic acid. In addition, the present invention provides new and improved therapeutic compositions including krill extracts and conjugated linoleic acid.

Progesterone-containing compositions and devices that can maintain opening of a body passageway are described. One aspect of the invention provides a therapeutically effective (e.g., relaxative, anti-oxidative, anti-restenotic, anti-angiogenic, anti-neoplastic, anti-cancerous, anti-precancerous and / or anti-thrombotic) composition or formulation containing progesterone and optionally vitamin E and / or conjugated linoleic acid. Another aspect of the invention provides a drug eluting device, such as a drug eluting stent, with at least one coating layer comprising a progesterone composition that can minimize or eliminate inflammation, thrombosis, restenosis, neo-intimal hyperplasia, rupturing of vulnerable plaque, and / or other effects related to device implantation, treatment, or interaction. Other aspects of the invention provide for methods of using such compositions, formulations, and devices.

The present invention is directed to a novel progression of topical and oral administration or use of lactoferrin or lactoferrin and other biological ingredients to prevent and treat dermatological conditions or disorders in humans. More specifically, the present invention is directed to the administration of lactoferrin in a topical material such as an ointment or cream to the skin of humans and also including a oral administration, together the topical and oral administration has a synergetic effect in the treatment of the skin. The progression of medicaments of the present invention are: 1) lactoferrin; 2) lactoferrin and conjugated linoleic acids; 3) lactoferrin, a plant or animal derived lipid and oblepicha; 4) lactoferrin, a plant or animal derived lipid, oblepicha, and an omega fatty acid; and 5) lactoferrin, a plant or animal derived lipid, oblepicha, an omega fatty acid and a whey protein.

The present invention is directed to compositions containing a conjugated linoleic acid derivative, a banaba extract and an extract of Phaseolis vulgaris and methods of treatment for weight loss.

The invention relates to a nutritive defatting food. The nutritive defatting food comprises the following components of whey protein concentrate, hydrolyzed fish collagen protein, soy protein isolate,rice protein, inulin, psyllium husk, resistant dextrin, resistant starch, chenopodium quinoa willd, konjaku flour, chia seeds, fructo-oligosaccharide, xylooligosaccharide, isomaltulose, erythrite, steviosides, linseeds, linseed oil, CMC, medium chain triglyceride, conjugated linoleic acid glycerides, L-carnitine, ferment, complex vitamins, and composite mineral substances. The nutritive defattingfood is good in satiety, balanced in nutrients, and good in defatting effect.

A novel oil composition comprises an interesterified structured lipid component, the component being an interesterifcation reaction product of an amount of a medium chain triglyceride, an amount of a long chain domestic oil, and an amount of a conjugated linoleic acid material. The structured lipid component can be used in edible oil compositions. The oil compositions advantageously can contain an amount of a phytosterol ester component, up to about 12 weight percent of the total composition. The oil compositions disclosed herein have good stability and also have other properties useful for an edible oil composition.

The invention discloses a method for transforming fatty acid ethyl ester into glyceride, which comprises the following steps of: mixing the fatty acid ethyl ester and glycerol in a material tank; making the material pass through a glycerol separator by using a pump to separate free glycerin; then putting the material in a reactor in which immobilized lipase is filled; and making the material passthrough a packed tower to remove ethanol; making the material finally flow back to the material tank for performing 6 to 300h circular reaction; then carrying out molecular distillation on the reaction product to remove the unconverted reactant so as to obtain glyceride products. The method can improve the stability and bioavailability of the products, and has high application value for transforming functional fatty acids such as ethyl ester fish oil, algae oil, conjugated linoleic acid, arachidonic acid and the like into glyceride products.

Conjugate linoleic acid or cnojugate linoleate microcapsule consists of wall material, capsule core, assistant, surfactant and plasticizer. Capsule core is added into wall material water solution and emulsified while adding assistant, surfactant and plasticizer; and the microcapsule product is obtained through spray drying. Great amount of experiment shower that the product has high antioxidant performance and high store stability, can mask bad smell, avoid mutual effect of different incompatible food components and decrease degradation reactions and reach controlled release. The present invention may be used in health food, food additive and feed additive and has health functions of anticancer, resisting arteriosclerosis, regulating metabolism, strengthening body's immunity, regulating blood sugar, etc.

The invention relates to a cereal meal replacement stick for fat loss and a preparing method thereof. The cereal meal replacement stick is prepared from concentrated whey protein, calcium caseinate, soybean isolate protein, hydrolysis fish collagen, konjac flour, psylliumseedhusk powder, a white kidney bean extract, a potato extract, conjugated linoleic acid glyceride powder, DSM fabuless palm oilpowder, freeze-dried fruit powder, beet juice powder, mixed cereal powder, mixed tocopherol concentrate, active probiotic powder, a compound nutrient supplement, freeze-dried fruit particles, nut grains, chia seeds, puffing cereal particles, puffing soybean protein grains, isomalto-oligosaccharide, fructo-oligosaccharide, resistant dextrin, glycerinum and high-oleic-acid sunflower seed oil. The preparing method specifically comprises the following steps of syrup boiling, material mixing, forming, cooling, cutting and coating or non-coating. The meal replacement stick has the advantages of energy negative balance, strong satiation, low sugar increase and full nutrition, and the health and vigor of the body are guaranteed while dieters lose weight and fat.

A cosmetic water-in-oil composition is provided which includes a water-in-oil emulsifying silicone surfactant, an ultrafine titanium dioxide and conjugated linoleic acid. The presence of conjugated linoleic acid stabilizes the composition against color degradation and also maintains an approximately steady viscosity.

A method of stabilizing and potentiating actions and administration of neurotrophins such as brain-derived neurotrophic factor (BDNF), neurotrophin-3, neurotrophin-4, and nerve growth factor and their receptors by using in coupling conjugation with polyunsaturated fatty acids (PUFAs) in the prevention and / or treatment of obesity, type 2 diabetes mellitus, metabolic syndrome X, Alzheimer's disease, depression, Parkinson's disease, and schizophrenia is described. The invention is directed to the efficacious use of various neurotrophins by using them in combination with polyunsaturated fatty acids chosen from linoleic acid, gamma-linolenic acid, dihomo-gamma-linolenic acid, arachidonic acid, alpha-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, cis-parinaric acid, docosapentaenoic acid and conjugated linoleic acid in predetermined quantities. The invention also provides methods of efficiently delivering neurotrophins to the desired areas of the brain by complexing or conjugating with PUFAs, so that they are able to cross blood brain barrier efficiently and reach the desired regions of the brain in adequate amounts.

The present invention discloses a weight losing and slimming nutrition package which is characterized by containing the following components in mass percentages: 4%-6% of isomaltooligosaccharide, 3.4%-5.2% of inulin, 14%-21% of malt dextrin, 2.4%-3.6% of fructo-oligosaccharide and 2.0%-3.0% of conjugated linoleic acid glycerides. The weight losing and slimming nutrition package also includes and is blended from the following raw materials: skim milk powder, soybean milk powder (instant soybean flour), whole milk powder, soybean protein isolate, whey protein powder, soybean peptide powder, purified konjac powder, cassia seed extract, lotus leaf extract, compound vitamins, compound minerals, calcium carbonate, L-carnitine, and ethyl vanillin. By conducting compounding of dietary fibers, and combining the soybean peptide powder, cassia seed extract, lotus leaf extract, conjugated linoleic acid glycerides and L-carnitine substances, the nutrition package plays roles in keeping fit and losing weight and slimming, and is especially suitable for the consumption of people with obesity and females demanding slimming and beautifying skin.

The present invention relates to the unexpected discovery that a combination of effective amounts of carnitine (in any form, as described in further detail herein) and conjugated linoleic acid (CLA) administered to a patient in need thereof exhibits synergistic activity in treating obesity by reducing fat mass and overall weight as well as one or more of hyperlipidemia, hypercholesterolemia, diabetes (both diabetes mellitus I and II), metabolic syndrome (syndrome X), kidiney failure and high blood pressure, where those conditions exist.

The invention belongs to the fields of animal nutrition and feed science, relates to a diet preparation technique for the production of functional mutton which is rich in lycopene and conjugated linoleic acid (CLA) by mutton sheep, and is applicable to mutton sheep at the fattening period. The diet comprises the following raw materials: corn, tomato pomace, soybean meal, cotton meal, wheat bran, sunflower meal, corn stalk, and the like. Because tomato pomace that is rich in lycopene and linoleic acid is added into the diet, not only the mutton produced by the mutton sheep at the fattening period contains lycopene, but also the content of conjugated linoleic acid (CLA) in the mutton is increased, which can enhance mutton sheep immunity and reduce feed cost.

The invention discloses a feed formula capable of improving carcass quality of ducks. The feed formula comprises adding 0.5-1.0 parts by weight of conjugated linoleic acid in daily rations of the ducks during a whole process; adding 8-15 parts by weight of feed grade jujube date powder in a fattening process of the ducks; and adding 0.05-0.1 parts by weight of Chinese herb extracts in the feed of the ducks during the whole process. The feed formula can meet all the nutrient need for growth of the ducks, increases a muscle rate of the carcasses, reduces percentages of abdominal fat and intermuscular fat, improves antioxidant activity of all parts of the carcasses, facilitates feed intake mass of the ducks, improves the quality of meat, greatly reduces the cost of the feed, improves disease resistance of the ducks, and reduces drug residues in the carcasses of the ducks because antibiotics can not be used in the fattening period.

A method for the treatment of carcinoma in a human is disclosed, including administering to a human a therapeutically effective amount of 9-cis, 11-trans octadecadienoic acid formed by reacting an ester of ricinoleic acid with a tosyl chloride or a mesyl chloride to form a tosylate or mesylate of an ester of ricinoleic acid, and reacting the tosylate or mesylate of an ester of ricinoleic acid with diazabicyclo-undecene. The method includes administering to a human a purified conjugated linoleic acid (CLA) produced by a novel synthesis process for producing 9-cis, 11-trans octadecadienoic acid at room temperature in high yield including providing a tosylate or mesylate of a methyl ester of ricinoleic acid and providing a purified 9-cis, 11-trans octadecadienoic acid formed when the tosylate or mesylate reacts with diazabicyclo-undecene.

The invention relates to a solid beverage and the preparation method thereof. In the invention a plurality of novel nutritive additives which are blended in reasonable proportions are adopted to achieve the needed effect. The detailed ingredients and the weight proportions (percent) thereof are as follows: 30 to 40 percents of concentrated lactalbumin, 28 to 32 percent of whole milk powder, 5 to 10 percent of oligermerized isomaltiooligosaccharide (IMO), 3.5 to 5 percent of water soluble dietary fiber, 12 to 19 percent of natural fruit powder, 0.8 to 1.5 percent of medium chain triglyceride, 0.9 to 1.5 percent of premix of vitamins and minerals, 0.8 to 1.5 percent of glutamine, 0.7 to 1.2 percent of L-carnitine, 0.2 to 0.5 percent of conjugated linoleic acid, 1 to 1.5 percent of shark cartilage, 3.8 to 5.9 percent of dimethyl sulfone, 0.2 to 0.5 percent of hexadecadienoic acid, 1.5 to 2 percent of amino glucose and 0.5 to 1 percento of glycoprotein. Made by adopting quality protein and carbohydrate as major preferred materials, and adding various novel functional nutritive raw materials properly, the solid beverage is suitable for the population involving with sports.

The invention relates to a preparation method of conjugated linoleic acid, comprising the following steps: placing the vegetable oil containing linoleic acid glyceride or mixed fatty acid containing linoleic acid or extracted and separated linoleic acid product as raw material, low boiling point alcohols solvent and base catalyst into a reaction kettle and performing the isomerization reaction at a certain temperature. The reaction product is subjected to evaporating, acidifying, extracting and vacuum drying to obtain the conjugated linoleic acid. The conversion of the linoleic acid is above 97.5% and the total yield of the conjugated linoleic acid is above 85%, the proportions of the cis-9, trans-11 isomer and trans-10, cis-12 isomer in the total conjugated linoleic acid are above 96%. The preparation method has features of less reaction steps, easy recovery and repeated use of solvent, simple follow-up separation, low production cost, and easy industrialization.

The invention relates to a novel microorganism feed additive, in particular to a microorganism feed additive which contains bacterial strain that can produce conjugated linoleic acid and a preparation method thereof, which belongs to the microorganism feed additive technical field. The preparation method of the microorganism feed additive is that plant lactobacillus and enterococcus faecalis are respectively processed by zymotic liquid which is cultured by liquid deep-layer high-density fermenting and are made into powder by a micro-capsule peridum spray drying method and a frozen-dried preparation method. The microorganism feed additive transforms linoleic acid into the conjugated linoleic acid in the intestinal tracts of poultry and livestock, which takes effects of promoting the growth performance of the poultry and the livestock, reducing fat, increasing meat factor and regulating immunity reaction, etc., and the microorganism feed additive also solves the problem of the high expense caused by adding the conjugated linoleic acid into the feed directly. The microorganism feed additive prepared by the method has the advantages of high viable bacteria content, long holding period and little microbial pollution.

The present invention discloses a solid drink having weight losing and body slimming functions. The solid drink is prepared from the following raw materials according to a certain proportion: soybean protein isolate, whey protein, L-carnitine, tartrate, chitin, conjugated linoleic acid glyceride micro-capsule powder, a cassia seed extract, skim milk powder, collagen powder, soybean lecithin, a lotus leaf extract, a white kidney bean extract, polydextrose, isomaltooligosaccharide, enzyme powder, konjac flour, sodium carboxymethyl cellulose and excipients of essence pigments and maltodextrin. The solid drink takes into account the comprehensive needs of people taking the solid drink in nutritional supplement, metabolic regulation, satiated meal, taste in taking, etc., avoids the common problems of the existing weight losing products to the human body, contains the necessary functional components for the weight losing, also considers the accessory functions of regulating gastrointestinal functional regulations, blood lipids and cardiovascular and cerebrovascular health, improving skin, etc., fully blends and supplements the various functional components, plays the weight losing and body slimming effect, and also has a certain health-care role.

The present invention relates to a combination of a hermetically sealed, substantially air-tight container and a nutritional composition. The container of the present invention is adapted for the convenient transport, and storage of a single daily oral dose of a nutritional composition containing a fatty acid, for example, diacyl glycerol, an octadecatrienoic acid, an octadecadienoic acid, linolenic acid, linoleic acid, conjugated linoleic acid (CLA) or a combination thereof. In a preferred embodiment, the present invention relates to the use of the c9, t11 and t10, c12 isomers of CLA in a nutritional composition. The wide range of health benefits associated with consumption of these CLA fatty acids is well known. Furthermore, the invention relates to a container that substantially prevents CLA lipid oxidation caused by exposure to air.

The invention relates to bifidobacterium breve C11 (CCFM683) and application thereof. According to the invention, bifidobacterium breve C11 (CCFM683) can respectively effectively converter free linoleic acid and linolenic acid into conjugated linoleic acid and conjugated linolenic acid with better biological activity, can be directly used for preparing conjugated linoleic acid or conjugated linolenic acid, and can also be used for producing food rich in conjugated linoleic acid or conjugated linolenic acid.

The invention discloses a method for preparing conjugated linoleic acid by using Idesia polycarpa Maxim oil, which belongs to the fields of medicine, food and feedstuff. The technology comprises four aspects of acid-process degumming of crude oil, preparation of mixed fatty acid, extraction of linoleic acid and conjugation. The method is characterized in that degummed oil is obtained through acid degumming process, and phospholipid is thoroughly removed; direct saponification preserves dissociative linoleic acid and avoids the yield loss; the technical processes of carbamide inclusion, alkali isomerization of the linoleic acid and the like are optimized to avoid the application of toxic reagents so as to obtain the conjugated linoleic acid with high quality and high conversion rate; at the same time, the technical processes are simple with low equipment requirement, recover the solvent effectively, reduce the cost significantly, and have wider application prospect in the production of high-quality conjugated linoleic acid.

Cyclodextrin coated microcapsule consists of coated matter, cyclodextrin and antioxidant. The coated matter is added into cyclodextrin or its solution while adding antioxidant and stirring and the microcapsule product is obtained through cooling, vacuum filtering and freeze drying. The product has the same physiological activity as conjugate linoleic acid and its derivative as well as high antioxidant performance and high stability. The present invention may be used in health food, food additive and feed additive and has health functions of anticancer, resisting arteriosclerosis, regulating metabolism, strengthening body's immunity, regulating blood sugar, etc.

A nutrient containing the conjugated linoleic acid for the people who is going to lose weight is prepared from 9 raw materials including protein, edible fibres fatty acid, inorganic salt, vitamine, useful bacteria, soybean isoflavone, etc.

The present invention relates to the use of conjugated linoleic acid (CLA) for the topical treatment of fatty deposits and cellulite and to new topical compositions and to cosmetic and dermatological topical compositions for the treatment of fatty deposits and cellulite comprising CLA as well as kits comprising CLA for said treatment.

The invention discloses a disease-resistant nursery piglet feed without antibiotics. The disease-resistant nursery piglet feed is prepared from the following components in parts by weight: 0.5 to 1.0 part of conjugated linoleic acid, 0.2 to 0.8 part of acidifying agent special for sows, 0.01 to 0.05 part of chitosan oligosaccharide, 0.01 to 0.05 part of cinnamyl aldehyde, 0.01 to 0.05 part of curcumin, 0.02 to 0.08 part of tannic acid, 0.1 to 0.5 part of nucleotide, 0.01 to 0.08 part of microecological preparation, 0.01 to 0.05 part of phytase, 0.01 to 0.05 part of compound enzyme and the like, and is free from antibiotics. The invention further provides a preparation method for the feed. The feed has the effects of improving disease resistance and survival rate of nursery piglets, and avoiding drug resistance risk caused by use of antibiotics.

The production process of selenium-rich low-cholesterol health egg includes the following steps: sorting and adding selenium-rich dry yeast as organic selenium source; sorting and adding conjugate linoleic acid; compounding and adding Chinese herbal medicine preparation; compounding the three kinds of powder of selenium-rich dry yeast, conjugate linoleic acid and Chinese herbal medicine preparation to form the pre-mixed material for producing selenium-rich low-cholesterol health egg; and adding the pre-mixed material to laying fowl feed and feeding with the feed. The present invention has relatively low cost in producing selenium-rich and CLA-rich egg with low cholesterol content, and the added Chinese herbal medicine preparation can promote the absorption and deposition of selenium and CLA and is beneficial to the health of the laying fowl and human body.

The invention relates to weight-losing soft capsules, which comprise soft capsule bodies and a capsule content, and are characterized by being prepared by the following steps: weighing the content including 60 to 80 weight percent of conjugated linoleic acid, 5 to 15 percent of L-carnitine, 5 to 15 percent of green tea extract, 1 to 10 percent of konjaku flour, 1 to 10 percent of blueberry extract, uniformly stirring, grinding, and degassing; weighing gelatin, water and glycerol according to a ratio of 100:100:40, heating to dissolve the material, and degassing to obtain capsule body filtrate; and delivering the capsule body filtrate and the content to a pelleting press to make pellets, sizing, drying, washing pellets, sorting and packaging to obtain the finished product. The konjaku flour, blueberry extract, conjugated linoleic acid, L-carnitine and green tea extract, which are selected in the invention, act together to achieve an optimal weight-losing effect. The dose is scientific, and the weight-losing soft capsules have health-care effects; and the preparation method is reasonable in process and high in operability and makes large-scale production easy.