Product
Eureka
For R&D, Eureka makes reading and utilizing patents & technical documents easy.
Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
46 results about "Yohimbine" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Yohimbe has been used for sexual function problems (decreased sexual ability/desire).
Formulations and use of controlled-release indole alkaloids
InactiveUS6416793B1Efficient and sustained administrationGreat and more sustained gastrointestinal absorptionBiocidePowder deliveryControlled releasePhytochemical
The present invention relates to spray dried hydrophobic phytochemical (i.e., yohimbine and ibogaine) compositions, a process for making such compositions and a method of using such compositions for, e.g., the promotion of weight loss. Typically, the hydrophobic dietary compositions of the present invention exhibit enhanced absorptivity when taken orally.
Owner:BIORESPONSE
Inhibition of RNA function
Inhibition of RNA function, and treatment or control of diseases or conditions, e.g. infectious diseases such as viruses and viral infections (including HIV) and microbial infections, by the contacting of the RNA with a compound having a central or core structure comprising three fused rings containing from 12 to 15 ring atoms, the central ring including at least one heteroatom selected from nitrogen, oxygen and sulfur, the atoms of the three-ring core structure being optionally substituted with substituents such as halogens, cyano, and / or various substituted or unsubstituted aliphatic and / or heteroaliphatic moieties, or contacting the RNA with yohimbine, usnic acid or N-{4-[2,5-Dioxo-1-(4-trifluoromethoxy-phenyl)-pyrrolidin-3-yl]-phenyl}-2,2,2-trifluoro-acetamide. Preferred compounds are various phenothiazines, including both known and novel compounds.
Owner:RGT UNIV OF CALIFORNIA
Weight control compositions and methods
InactiveUS20050025844A1Decreasing body fatIncreasing and maintaining lean body massBiocideUnknown materialsN-MethyltyramineReceptor antagonist
The present invention provides compositions and methods that assist in providing weight control. Compositions comprise Caffeine, an adrenergic amine (e.g. synephrine, hordenine, octopamine, tyramine and N-methyltyramine,) forskolin, Guggulsterones, an alpha-2 receptor antagonist (e.g. Yohimbine) and a vinca alkaloid (e.g. vinpocetine.) Black pepper extract may be added as well in various alternative embodiments. Methods utilizing administration of nutrient compositions are disclosed as well.
Owner:SELLO AZUL
Composition and method for supporting thermogenesis and lipid oxidation
InactiveUS20080138449A1Good for weight lossIncreasing fat oxidationBiocideOrganic active ingredientsLipid oxidationYohimbine
A nutritional composition and method is provided for promoting weight loss or weight maintenance in an individual by supporting and enhancing thermogenesis and lipid oxidation comprising therapeutically effective amounts of yohimbine or derivatives thereof, an effective amount of Evodia rutaecarpia extract and a source of an effective amount of L-carnitine or derivatives thereof.
Owner:H3 FORMULATIONS LTD
Combiner capable of promoting movement function and sexual function
InactiveCN102578588AImprove fatigue resistanceImprove animal performanceFood preparationSexual functionTribulus terrestris
The invention discloses a combiner capable of promoting the movement function and the sexual function. The combiner comprises 4-48 parts by weight of yohimbine hydrochloride, 5-150 parts by weight of icariin, 20-300 parts by weight of tribulus terrestris protodioscin, 10-600 parts by weight of eurycoma longifolia extract, 10-600 parts by weight of maca extract, 10-500 parts by weight of taurine, 10-100 parts by weight of zinc aspartate, 150-1350 parts by weight of magnesium aspartate and 0.1-5 parts by weight of vitamin B6.
Owner:SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI
Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient
ActiveUS20090005430A1Simple structureSimilar effectBiocideAnimal repellantsHalogenVascular dilatation
It is intended to find a compound that is structurally simpler than yohimbine, a pentacyclic condensed heterocyclic compound, and has an effect similar to that of yohimbine.The present invention relates to a pharmaceutical or food composition for α2 receptor blockage comprising a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof:(wherein R1 represents a hydrogen, alkyl group, alkenyl group, alkynyl group, aromatic group, aralkyl group, acyl group, arylsulfonyl group, alkylsulfonyl group, or hydroxyl group; R2 represents a hydrocarbon group; R3, R4, R5, R6, and R7 are the same or different and represent a hydrogen, halogen, alkyl group, or alkoxy group; R8 represents a hydrogen or acyl group; n represents an integer of 1 to 6; and a and b are the same or different and represent 1 or 0).
Owner:KANAZAWA UNIV +1
Pharmaceutical composition for improving male animal sexual dysfunction
InactiveCN103948742AImprove sexual dysfunctionImprove fertilityOrganic chemistrySexual disorderSexual dysfunctionMedicine
The invention provides a pharmaceutical composition for improving male animal sexual dysfunction. The pharmaceutical composition comprises the following material medicines in parts by weight: 4-6 parts of fruits of Chinese wolfberry, 2-4 parts of seeds of Chinese dodder, 1.5-3.5 parts of raspberries, 1-2 parts of schisandra chinensis, 1-2 parts of semen plantaginis and 1.5-2.5 parts of yohimbine. According to the invention, the five traditional Chinese medicines such as fruits of Chinese wolfberry, seeds of Chinese dodder, and the like are matched with the yohimbine extract to use, so that the improvement effect on male animal sexual dysfunction is obviously superior to that of the classical prescription wuzi yanzong pill; and meanwhile, after being matched for use, the medicines effectively avoid adverse reaction of the yohimbine, so that a safer and more effective novel choice is provided for clinical medication.
Owner:SICHUAN SAINTHOOD BIOTECH
Maintaining gel capable of strengthening yang and nourishing kidney, for male sexual dysfunction, and production method of maintaining gel
InactiveCN110585328ADilated blood vesselsIncrease blood flowAerosol deliveryOintment deliverySide effectOfficinalis
Owner:孙廷柱
Method for predicting and modeling Anti-psychotic activity using virtual screening model
InactiveUS20130184462A1Effective controlChemical property predictionOrganic chemistryStrong bindingDrug discovery
The present invention relates to the development of a virtual screening model for predicting antipsychotic activity using quantitative structure activity relationship (QSAR), molecular docking, oral bioavailability, ADME and Toxicity studies. The present invention also relates to the development of QSAR model using forward stepwise method of multiple linear regression with leave-one-out validation approach. QSAR model showed activity-descriptors relationship correlating measure (r2) 0.87 (87%) and predictive accuracy of 81% (rCV2=0.81). The present invention specifically showed strong binding affinity of the untested (unknown) novel compounds against anti-psychotic targets viz., Dopamine D2 and Serotonin (5HT2A) receptors through molecular docking approach. Theoretical results were in accord with the in vitro and in vivo experimental data. The present invention further showed compliance of Lipinski's rule of five for oral bioavailability and toxicity risk assessment for all the active Yohimbine derivatives. Therefore, use of developed virtual screening model will definitely facilitate the screening of more effective antipsychotic leads / drugs with improved antipsychotic activity and also reduced the drug discovery cost and duration.
Owner:COUNCIL OF SCI & IND RES
Composition capable of promoting movement function and sexual function
InactiveCN102578588BImprove fatigue resistanceImprove animal performanceFood preparationSexual functionMedicine
Owner:SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI
Compound antagonist of animal anesthetic and application of compound antagonist
InactiveCN102389432AGood wake up effectSignificant experimental wake-up effectOrganic active ingredientsAntinoxious agentsFlumazenilYohimbine
The invention discloses a compound antagonist of an animal anesthetic and an application of the compound antagonist, belonging to a medicine composition in the field of veterinarian. Each ml of compound antagonist comprises active ingredients of 0.5-2.0mg of Yohimbine hydrochloride and 0.1-0.4mg of flumazenil hydrochloride. The compound antagonist of the animal anesthetic has a remarkable awakening effect to an anesthetized animal, better effect compared with the single use of the Yohimbine hydrochloride or the flumazenil hydrochloride, is rapid in awakening, has no any adverse effect, is stable in recovery of circulating and breathing mechanisms, and has large safety factor and clinical application safety.
Owner:NANJING AGRICULTURAL UNIVERSITY
Functional food capable of increasing male sexual function
ActiveCN101422570AStart fastSignificant effectOrganic active ingredientsMammal material medical ingredientsDiseaseEpimedium
The invention discloses a functional food helping improve male sexual function and the effective components thereof are prepared with materials with the following weight proportion: 10 to 60g of aweto, 10 to 60g of yohimbine extracts, 200 to 400g of prepared rhizome of rehmannia , 300 to 900g of epimedium, 100 to 400g of raspberry, 100 to 400g of sealwort and100 to 400g of endothelium corneumgigeriae galli. Hence, the functional food can rapidly show effect, is effective in treatment, can completely cure male erectile dysfunction and effectively improve male sexual function.
Owner:中欣营养健康产业技术研究院(山东)有限公司
Method for extracting multiple alkaloids from rauvolfia vomitoria
InactiveCN102627641AHigh purityOrganic chemistryPlant ingredientsAjmalineReversed-Phase Liquid Chromatography
The invention discloses a method for extracting multiple alkaloids from rauvolfia vomitoria. The method comprises the following steps of: adding acid-containing ethanol aqueous solution into root powder of the rauvolfia vomitoria, stirring and filtering to obtain leach liquor; concentrating the leach liquor, adsorbing with non-polar macroporous adsorption resin, washing and eluting with 40 percent ethanol and 80 percent ethanol; collecting eluate respectively, concentrating and then adsorbing with weakly acidic cation exchange resin, washing and eluting with 50 percent ethanol; collecting eluate respectively, adjusting pH to be 3 by using concentrated acid, concentrating and then adsorbing with a C18 reversed phase chromatography medium and eluting with the ethanol aqueous solution with gradually increasing concentration; and collecting the eluate in stages respectively, combining the parts with higher single alkaloid purity in the eluate respectively, concentrating to obtain solid, adding an organic solvent to crystallize to obtain crystals of yohimbine, ajmaline, reserpoid, reserpine and rescinnamine. According to the method, five alkaloids can be extracted from a plant at most at one time; and the method has the advantages of few steps, less dosage of the used organic solvent, low pollution and simple required equipment.
Owner:SHANGHAI JIAO TONG UNIV
External preparation for preventing and treating male sexual dysfunction and application thereof
InactiveCN111840508APromote sinusoid fillingQuick effectHydrolysed protein ingredientsAerosol deliverySexual functionMedication injection
The invention discloses an external preparation for preventing and treating male sexual dysfunction. The external preparation comprises mesenchymal stem cell supernatant, water-soluble laurocapram, arginine, taurine, peppermint oil, small molecular oyster peptide, ginsenoside extract, yohimbine extract, lubrajel and double distilled water. Every 200ml of finished product comprises the following components in percentage by volume / volume: 15% of mesenchymal stem cell supernatant, 2% of water-soluble laurocapram, 2% of peppermint oil and 6% of lubrajel. The external preparation further comprisesthe following components in percentage by mass / volume: 5% of arginine, 5% of taurine, 2.5% of small molecular oyster peptide, 2% of a ginsenoside extract and 2% of a yohimbine extract, and the balanceof double distilled water which is quantified to 200ml. The external preparation can promote the blood sinus filling of the cavernous body of the penis, has a direct effect on the aspects of erectionassistance, time delay, thickening and the like, and has the advantages of quick response, good curative effect and high safety. The externally-applied smearing formula reduces the risk caused by oral administration and penis local drug injection.
Owner:北京清大赛尔生物科技有限公司
Composition containing tenuifoliside and ginsenoside
InactiveCN104840527AIncreased toxicityReduced forced swim immobility timeNervous disorderPlant ingredientsCurative effectPharmaceutical drug
The invention provides a composition containing tenuifoliside and ginsenoside. The composition is formed by tenuifoliside and ginsenoside in a weight ratio in a range of 0.5:0.5 to 0.11:0.89. Single effective tenuifoliside and ginsenoside are extracted from tenuifoliside and ginsenoside medicine materials, and both reach more than 50%. The composition can be applied to preparation of medicine for treating and improving depression. Two effective parts are combined, and accordingly, the mouse yohimbine toxicity is enhanced apparently, and the mouse forced swimming unmovable time is shortened apparently. By combining the two effective parts, the effect is enhanced compared with the effect of single use of any one part. By means of the composition, medicine definitive in curative effect and slight in adverse reaction is provided for treating and improving depression.
Owner:ZHEJIANG UNIV
Yohimbine derivatives and use thereof
Yohimbine derivatives are disclosed having modification of the C-16 carboxyl group to include a sidechain and where the resulting derivative does not possess a second yohimbine pharmacophore (i.e., the compound is not a yohimbine dimer). The yohimbine derivatives of the present invention are preferably characterized by selective activity as α2c-AR antagonists. Use of the compounds, or pharmaceutical composition containing them, for treating or preventing an α2c adrenergic receptor mediated condition or disorder, and for antagonizing activity of an α2c adrenergic receptor are also disclosed.
Owner:TENNESSEE RES FOUND THE UNIV OF +1
Method for creating animal model of rat's minimal brain dysfunction (MBD)
A method for creating the animal model of rat, which is used for screening the related medicine and evaluating the related therapy for restless syndrome, features that the specific antagonist "Yohimbine" for alpha-2 receptor is injected into the local region of the prefrontal lobe of rat with a micro-quantity to block the function of apha-2 receptor and directly induce the restless syndrome of the rat.
Owner:FUDAN UNIV
Antipsychotic agents and standardized antipsychotic fractions from Rauwolfia tetraphylla and process of their isolation
Owner:COUNCIL OF SCI & IND RES
Capsule for treating male sexual dysfunction and preparation method thereof
InactiveCN103877160ARepair Erectile DysfunctionPromote growth and developmentOrganic active ingredientsCapsule deliveryDamiana extractPenile Tumescence
The invention provides a capsule for treating male sexual dysfunction and a preparation method thereof. In the capsule, intermediates and monomers of natural plant extracts are taken as raw materials. The capsule comprises the following components in parts by weight: 100-200 parts of damiana extract, 50-120 parts of L-arginine, 50-100 parts of ginseng root saponin, 5-10 parts of yohimbine and 50-100 parts of gorgon euryale seed extract. By taking the capsule, erectile dysfunction can be repaired, the growth and development as well as erection hardness of penis are promoted, the effects of nourishing essence and reinforcing kidney to secure essence are achieved, and the length of encounter is prolonged.
Owner:杜志政 +1
A pharmaceutical composition for improving male animal sexual dysfunction
InactiveCN103948742BImprove sexual dysfunctionImprove fertilityOrganic chemistrySexual disorderSexual dysfunctionMale reproductive system
Owner:SICHUAN SAINTHOOD BIOTECH
Receptor blocker and vasodilator comprising indole derivative as active ingredient
Owner:KANAZAWA UNIV +1
Constitution method of monkey hyperkinesia animal model
The invention belongs to the areas of the medical evaluation and detecting technique, particular relates to the modeling method for fitlering the medication to treat the disease of motion too much and for evaluating the method of monkey animal model for treating the said diseases. Idiosyncratic antagon (yohimbine) in minute quantities of a2 acceptor are injected to the local area of the monkey prefrontal lobe, in order to block out the function of the a2 acceptor. Inducing the disease by experimental media directly builds the animal model of the said disease. The model can be used to filter the medication and evaluate the method for treating the disease.
Owner:FUDAN UNIV
Yohimbine hapten YHA, artificial antigen and antibody thereof, and preparation and application thereof
The invention discloses a yohimbine hapten YHA, an artificial antigen and an antibody thereof as well as preparation and application thereof. The preparation method comprises preparing a yohimbine hapten YHA, wherein the structural formula of the yohimbine hapten YHA is shown as a formula (I); preparing a yohimbine artificial antigen and a yohimbine antibody YHA-IgG by using the hapten. The antibody YHA-IgG has high detection sensitivity and strong specificity for yohimbine, the half inhibition concentration is 0.50 mu g / kg, the detection range for yohimbine is 0.12-2.18 mu g / kg, the lowest detection limit is 1.13 mu g / kg, and the detection requirements are met; besides, the preparation methods of the yohimbine hapten YHA, the yohimbine artificial antigen and the yohimbine antibody YHA-IgGare simple and low in cost, and a core raw material is provided for establishing an immunological detection method of specific yohimbine; therefore, the yohimbine antibody YHA-IgG has a wide application prospect in detection of yohimbine.
Owner:SOUTH CHINA AGRI UNIV
Diet supplement for causing weight loss
InactiveUS20100136147A1Reducing waist circumferenceBiocideOrganic active ingredientsDietary supplementCissus quadrangularis
A dietary supplement and method for supporting weight loss and reducing the waist circumference of an individual, the dietary supplement comprising an extract of Cissus Quadrangularis stem and leaf, an extract of Green Tea leaf and an effective amount of Caffeine Anhydrous. The dietary supplement may further comprise at least one of Chromium Polynicotinate, an extract of Soy Bean Albumin, Pyridoxine Hydrochloride, L-selenomethionine, Cyanocobalmin, Yohimbine Hydrochloride and Folic Acid.
Owner:NORTHERN INNOVATIONS HLDG
Nutritional compositions to increase and sustain blood ketone levels
This invention discloses a nutritional composition of matter that effectively reduces and stabilize glucose levels in the blood of mammals by deliberately inducing ketosis. The compositions comprise, Sodium Beta-Hydroxybutyrate, Potassium Beta-Hydroxybutyrate, Magnesium Beta-Hydroxybutyrate, Calcium Beta-Hydroxybutyrate, Ketone Esters, Medium Chain Triglycerides (MCT) with at least one or more from L-Leucine, L-Lysine, L-isoleucine, Caffeine, Yohimbine, Yohimbe, Berberine and Creatine or its derivatives (such as creatine salt, and Creatyl-L-leucine).
Owner:JHO INTPROP HLDG
Nutritional supplements affecting mood state
Nutritional supplement compositions for mood enhancement are disclosed. A nutritional supplement composition can include one or more of plant material from pine bark, plant material from a species of the genus Ephedra, caffeine, green tea, octopamine, quercetin, trimethylglycine, yohimbine, and niacin. Some nutritional supplement compositions may affect heart rate, blood pressure, and / or resting metabolic rate when ingested. Related processes are also disclosed.
Owner:TALBOTT SHAWN M +1
Application of yohimbine and berberine mixture in medicament preparation
InactiveCN100431542CImprove survival rateAntibacterial agentsOrganic active ingredientsBerberineMulti organ
Owner:JINAN UNIVERSITY
Method for extracting multiple alkaloids from rauvolfia vomitoria
InactiveCN102627641BHigh purityOrganic chemistryPlant ingredientsAjmalineReversed-Phase Liquid Chromatography
Owner:SHANGHAI JIAO TONG UNIV
Capsule for treating male sexual dysfunction and preparation method of capsule
InactiveCN106727977ARepair Erectile DysfunctionPromote growth and developmentOrganic active ingredientsCapsule deliveryPenisArginine
The invention provides a capsule for treating male sexual dysfunction and a preparation method of the capsule. The capsule comprises the following raw materials of intermediates and monomers of natural plant extracts in parts by weight: 90-200 parts of a maca extract, 50-120 parts of L-arginine, 50-100 parts of ginseng root saponin, 5-10 parts of yohimbine and 50-100 parts of a gorgon fruit extract. The capsule for treating male sexual dysfunction is capable of remedying penis erectile dysfunction, promoting growth and development and erectile stiffness of penises, nourishing vital essence and tonifying kidney and securing essence.
Owner:FOSHAN RUIJIAN SPORTS EQUIP CO LTD
A composition for improving athletic performance and relieving fatigue
ActiveCN105055932BImprove athletic abilityTroubleshoot faster restoresOrganic active ingredientsAntinoxious agentsMuscle tissueAntioxidative stress
The invention discloses a strong aphrodisiac maca agent. The strong aphrodisiac maca agent comprises, by weight, 13.3-36.4 parts of maca, 13.3-36.4 parts of oat, 6.7-27.3 parts of yohimbine and 26.7-54.5 parts of L-arginine-alpha-ketoglutarate. The strong aphrodisiac maca agent has the advantages that cell autophagy signal pathways in muscle tissues can be activated, the serum urea nitrogen contents can be reduced, the activity of superoxide dismutase of bodies can be improved, the antioxidant stress reaction of the bodies can be enhanced, accordingly, the sports ability can be obviously improved, and obvious fatigue relieving and fatigue elimination accelerating effects can be realized.
Owner:陈宁
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com