10 results about "Grafted chitosan" patented technology

A method for preparing silkworm pupa active peptide microcapsules and their applications are disclosed. In a microfluidic focusing droplet generation chip, an aqueous phase is injected into the chip through the main channel, and an oil phase is injected through two side channels. The resulting microdroplets are collected in the collecting phase to form microcapsules. The filter membrane has a pore size of 0.1-1 μm. The aqueous phase consists of sodium alginate and silkworm pupa protein peptides; the oil phase consists of one of mineral oil, soybean oil, silkworm pupa oil, corn oil, peanut oil, rapeseed oil, and lard; the collecting phase consists of caffeic acid-grafted chitosan and calcium chloride dissolved in acetic acid. By optimizing the formulation and process, droplets with good dispersibility in oil, uniform morphology and size, and good stability are prepared.

This invention relates to the field of water pollution control technology and discloses the preparation and application of modified chitosan adsorption balls. The invention involves grafting modified nano-micron high-purity composite active iron onto chitosan, then mixing it with dried and crushed sludge. The modified nano-micron high-purity composite active iron is then reacted with the chitosan to modify it. First, the surface of the nano-micron high-purity composite active iron is made to have active functional groups, and then it reacts with chitosan. At this point, the chitosan also has a dispersing effect, resulting in better performance and achieving a synergistic effect of dual phosphorus removal. This invention has low cost, simple operation, and good economic benefits.

The application discloses a kind of two-component modified binary polymer nanofiber array and its molecular model, preparation method and application, two-component modified binary polymer includes polyvinyl alcohol, chitosan, carbon nanotube, silver particle four components.Polyvinyl alcohol is grafted chitosan with hydrogen bond, polyethylene-chitosan is grafted carbon nanotube with covalent bond, silver particle is dispersed and supported in the gap and surface of polyethylene-chitosan-carbon nanotube nanofiber array.Polyvinyl alcohol and chitosan binary polymer have high interface affinity and stability, carbon nanotube has the function of dispersing binary polymer and electrical conductivity, silver component has electrocatalytic activity and electrical conductivity function, the two-component modified binary polymer nanofiber array obtained by the application has electrocatalytic reduction hydrogen peroxide, is applied to the construction of electrochemical sensor, realizes the high sensitivity and high stability detection hydrogen peroxide performance.

The present application relates to a kind of dolasetron mesylate suppositories, it is characterized in that, component includes: dolasetron mesylate, cyclodextrin or its derivative, shell matrix, hardness regulator, gel matrix, water;The gel matrix includes polyacrylic acid derivative grafted chitosan in it.The present application uses polyacrylic acid derivative grafted chitosan and cyclodextrin to prepare dolasetron mesylate liquid gel, significantly improve the stability and bioavailability of suppository;And can achieve the purpose of quick effect and slow release long-acting simultaneously.The suppository of the present application is very convenient for old people, children or patients who cannot be administered orally, and the treatment population of the product belongs to the patient who is inconvenient to swallow.

This application relates to the field of polymer material preparation technology, specifically to an antibacterial flexible core-sheath composite fiber and its preparation method. An antibacterial flexible core-sheath composite fiber includes a sheath layer and a core layer. The sheath layer raw material comprises the following components in parts by weight: 20-40 parts PE resin, 3-7 parts toughening agent, and 1-3 parts antioxidant. The core layer raw material comprises the following components in parts by weight: 8-12 parts composite antibacterial agent and 25-30 parts PET resin. The composite antibacterial agent includes gallic acid-grafted chitosan, zirconium-based metal-organic framework, and ε-polylysine-grafted sodium alginate. The antibacterial flexible core-sheath composite fiber of this application addresses the problem that existing core-sheath composite fibers cannot simultaneously achieve excellent mechanical properties such as flexibility and antibacterial properties, thus enabling the core-sheath composite fiber to possess both flexibility and long-lasting antibacterial properties.

The present application relates to a kind of compound acidifier for improving the feed intake of lactating sow and its preparation method, belong to the technical field of feed additive.The compound acidifier includes wall material and core material, the wall material includes cystine-gamma-polyglutamic acid and arginine-chitosan;The core material includes organic acid, organic acid salt and fermentation broth.The compound acidifier of the present application uses cystine crosslinked gamma-polyglutamic acid and arginine grafted chitosan as wall material, forms microcapsule with intestinal target release function by wrapping organic acid, can effectively improve the utilization efficiency of acidifier and the feed intake of lactating sow.

This invention belongs to the field of food packaging technology and discloses a hydroxypropyl methylcellulose-coated fruit and vegetable preservation film and its preparation method. The preservation film is composed of hydroxypropyl methylcellulose and phenolic-quaternary ammonium salt grafted chitosan, supplemented with food-grade additives such as glycerol, glyceryl monostearate, sodium citrate, talc, and potassium sorbate, forming a composite coating material with good antibacterial, moisture-barrier, and gas control capabilities. By uniformly spraying this film solution onto the surface of fruits and vegetables and drying it with low-temperature hot air, the shelf life of fruits and vegetables can be significantly extended. Experiments show that the film can effectively inhibit the growth of *Escherichia coli* and *Penicillium*, while exhibiting low water vapor and oxygen permeability, good storage stability of the film solution, and no stratification or flocculation, making it suitable for industrial applications in fruit and vegetable preservation. This invention has the advantages of safe raw materials, simple process, and stable performance, making it suitable for widespread application in the green packaging and transportation of fresh fruits and vegetables.

The application discloses a kind of phenylboronic acid and dopamine grafted chitosan-manganese-based injectable hydrogel immunoadjuvant and its preparation method and application.The hydrogel takes chitosan as base material, constructs modified polymer by chemical grafting dopamine and phenylboronic acid;Manganese ion is loaded to form phenylboronic acid and dopamine grafted chitosan-manganese-based injectable hydrogel immunoadjuvant.The hydrogel is fixed antigen by physical adsorption, has the functions of targeted delivery, immune activation and controllable release, significantly enhances humoral immunity and cellular immunity.The hydrogel has the characteristics of low viscosity, supports simple injection, biodegradable and no local inflammatory reaction.Experiments show that the titer of the adjuvant is equivalent to that of Freund's adjuvant after immunizing mice, successfully used for preparing monoclonal antibody of gladiolus burkholderia, and constructs immune test strip, and the sensitivity reaches 5×10 5 CFU / mL.The application solves the problems of high toxicity, local damage and high cost of traditional adjuvant, and is suitable for vaccine development and immunodiagnosis.

The application provides a kind of nanocomposite, multifunctional antibacterial hydrogel and its preparation method and application, belong to the technical field of biomedical materials.The application mixes carbon nanotube and 1,3,5-tri (4-aminophenyl) benzene, carries out first reaction, then mixes with 2,5-dimethoxy benzene-1,4-dimethyl formaldehyde, acetic acid solution, carries out second reaction, after second reaction is finished, the precipitate is collected, the precipitate is washed, dried to obtain imine COF material;The imine COF material and the ethanol solution containing iron ions are mixed, ultrasonic, stirring, the precipitate is collected, the precipitate is washed, dried to obtain nanocomposite.Oxidized dextran solution is sequentially mixed with the nanocomposite, coffee acid grafted chitosan solution, and the multifunctional antibacterial hydrogel is obtained by gelation.The nanocomposite and the multifunctional antibacterial hydrogel can be used for synergistic killing of bacteria in infected wounds and regulation and repair of wound microenvironment.