8 results about "Pterostilbene" patented technology

This invention relates to the field of agricultural biotechnology, specifically to a rumen methane inhibitory composition for ruminants containing *Asparagus yew* and *Pterostilbene*. The active components of the composition include *Asparagus yew* and its preparations, and *Pterostilbene*, which are used in a predetermined ratio to reduce rumen methane production and alleviate hydrogen accumulation in ruminants.

The application belongs to the technical fields of synthesis of compounds and pharmaceutical applications, and discloses an anti-tumor pterostilbene piperazine conjugate as well as a preparation method and application thereof. The pterostilbene, piperazine and various substituents are spliced in one molecule by using a molecular hybridization method, a novel anti-tumor pterostilbene piperazine conjugate is synthesized, and it is found through anti-tumor activity research that the anti-tumor activity of the conjugate is obviously higher than that of the two pharmacophores alone, and the conjugate has the potential to become a novel anti-tumor drug. The pterostilbene piperazine conjugate is synthesized, and it is found for the first time that the compound has good anti-tumor activity, can significantly inhibit the proliferation of various tumor cells in vitro, including hepatocarcinoma, triple-negative breast cancer, colon cancer and ovarian cancer cells, has little toxicity to normal cells, and can inhibit the migration ability of tumor cells. Therefore, the compound synthesized by the application has good anti-tumor application prospect.

The application discloses a kind of composite microecological preparation and preparation method and application, belong to microbial technical field.The composite microecological preparation is core-shell structure, the core-shell structure is divided into inside and shell layer, inside includes Bifidobacterium adolescentis, shell layer includes metal polyphenol network and ficoll polysaccharide;The metal polyphenol network includes the complex coating formed by pterostilbene and calcium ion.The core is BA, the shell is made of FCPS, PTE, Ca 2+ Network composition, can protect Bifidobacterium adolescentis to reach intestine successfully and colonize, directly inhibit inflammatory response, and relieve CDI-induced mouse colitis and oxidative stress damage by regulating intestinal flora, indole and the generation of indole derivatives, solve the pain point that traditional microecological preparation probiotic survival rate is low, poor targeting, limited effect.

This invention discloses a pigment for scalp micropigmentation and its packaging bottle, relating to the field of cosmetic packaging technology. The pigment comprises a base carrier, a biomimetic coloring system, a stabilizing and bioactive system, additives, and water. It utilizes a compound coloring process of nano-plant carbon black, γ-iron oxide, and anatase titanium dioxide microspheres, combined with components such as pterostilbene, sodium hyaluronate, and ceramide NP, to achieve three-dimensional biomimicry, high stability, low irritation, and minimal smudging. The accompanying packaging bottle features a narrow medical-grade PETG bottle body, a bottom material-gathering cone, a hydrophobic inner wall, a one-way valve, and a controlled-discharge nozzle, with a residual rate ≤2%, aseptic sealing, and precise dispensing. This invention provides natural coloring, good compatibility, and high utilization, making it suitable for clinical and commercial promotion of scalp micropigmentation.

The application belongs to the technical field of medicine, and particularly relates to a blood vessel targeting anti-aging oral composition and application thereof. In view of problems such as endothelial dysfunction, matrix sclerosis and accumulation of senescent cells caused by vascular aging, the composition comprises active ingredients: beetroot extract, fisetin, salvianolic acid B, panax notoginseng total saponins, cocoa flavanol, pterostilbene, procyanidin B2, luteolin, nicotinamide riboside and astaxanthin. The composition is prepared by a process of adsorbing astaxanthin on beetroot extract, mixing other active ingredients, fillers and glidants after fisetin and salvianolic acid B are prepared into a solid dispersion, and sequentially cooperating each module, so that the pulse wave transmission velocity can be significantly reduced and the skeletal muscle capillary density can be increased, and the composition is mainly used for preparing a medicine for improving vascular stiffness, promoting microcirculation and removing vascular senescent cells.

The application provides a preparation point of pterostilbene and a preparation method and application thereof. The preparation point of pterostilbene is prepared from raw and auxiliary materials in a proportion of 1-5 parts by weight of pterostilbene, 1-5 parts by weight of a surfactant, 0.7-10 parts by weight of an organic solvent and 1-10 parts by weight of water. The preparation point of pterostilbene can significantly enhance the light emission intensity of pterostilbene and prolong the light emission time, simultaneously efficiently convert ultraviolet rays into visible light with a wavelength greater than 400 nm, and realize the overall improvement of light emission performance; and also exhibits excellent antioxidant activity. These excellent performances enable the preparation point to improve skin light damage through long-acting stable ultraviolet resistance, and remove free radicals and improve skin fineness through antioxidant efficacy, so as to realize the dual effects of long-acting whitening and skin protection, and have good practical popularization and application value.

The application discloses a kind of pharmaceutical compositions, it includes stilben compound and pharmaceutically acceptable adjuvant;Wherein, the stilben compound is Pterostilbene or its pharmaceutically acceptable salt, the pharmaceutically acceptable adjuvant includes glucosyl tangeritin and / or glycyrrhizic acid salt.The in vitro and / or in vivo test results show that the pharmaceutical composition provided by the application has good curative effect for preventing and / or treating drug-induced liver injury;Meanwhile, it can also significantly reduce serum transaminase level, alleviate the symptoms such as liver and spleen edema, and also has good inhibitory effect on proinflammatory cytokines.The test results further show that stilben compound and pharmaceutically acceptable adjuvant (including glucosyl tangeritin and / or glycyrrhizic acid salt) combination, good safety, and easy to dissolve, release and / or absorption etc., improve the bioavailability of Pterostilbene (PTE), have synergistic effect, and have good application prospect.

The application relates to the technical field of crushing devices, in particular to a raw material crushing device for production of pterostilbene, which comprises a crusher shell and a driving shaft arranged in the crusher shell, a disc is fixed on the driving shaft, pin shafts are uniformly distributed in the circumferential direction of the disc, a hammer head is rotatably arranged on the pin shaft, a deflection shaft is rotatably connected in the pin shaft and extends to the outside of the pin shaft, a linkage assembly is arranged in the pin shaft, the deflection shaft and the linkage assembly are embedded in the pin shaft, the arc-shaped guide rail piece on the inner wall of the crusher shell and the trigger structure are combined, and the dynamic adjustment of the angle of the hammer head is realized. The design makes the hammer head automatically deflect to the optimal impact angle when rotating to the feeding port, significantly improves the crushing efficiency, reduces the energy consumption, prolongs the service life of the equipment through the dispersion of the impact force, and is especially suitable for the fine production scene of pterostilbene and other raw materials with high extraction rate.