98 results about "Supramolecular chemistry" patented technology

The design and deposition of a sensing layer for room temperature SAW / BAW chemical sensors utilizing macrocyclic compounds in accordance with supra-molecular chemistry principles. The gas to be sensed is attached to the organic sensing film thus changing its visco-elastic properties and creating a mass increase of the film deposited on the surface of SAW / BAW devices. A direct printing method can be used as an additive, mask-less procedure to deposit metallic interdigital transducers and electrodes required for SAW / BAW devices, along with the deposition of a guiding layer and the organic films only on the location required by the sensing SAW / BAW principle of the sensor. Different thermal treatment solutions can be used for the consolidation of the gelly organic films deposited by the direct printing methods.

A method of preparing low water-soluble medicine into solid nanometer pharmaceutical formulation is disclosed. According to the characters of molecular aggregates such as supramolecular chemical micelles and vesicles, the formulation, which based on the hydroxypropyl-beta-cyclodextrin and phospholipid, is prepared under the condition of hyperthermia sterilization and decompression. Such nanometer formulation is sterile particle or powder with loose porosity. For directly intravenous use, the formulation has targeting activity, sustained release and long circulating characters. While as a solid oral product, it is fast-release, fast-effective, and improved bioavailability characters, and is readily melted in mouth. The formulation utilizes secure accessories, traditional equipments and methods, thus, it is suited to be used and manufactured widely. Also disclosed is intravenous formulation of anticancer paclitaxel, which characterized that there has no polyoxyethylenated castor oil in it. Such intravenous formulation is nonallergic so that it has higher security and efficiency compared to present commercially available paclitaxel formulations.

The invention relates the organagel and liquid crystal-gel and preparing method. The structural formula of liquid crystal-gel is (R-O(CH2)nO-C6H4-NHCONH-)3(-1, 3, 5-C6H3) (R: 4-CN-C6H4N=NC6H4-, n>=4), and the structural formula of gel is (CH3(CH2)n-NHCO-)3(-1, 3, 5-C6H3) (n>=8). The mixture can make dioxide hexacyclic ring form organagel. The method comprises the following steps: heating the mixture, at the course of cooling, forming lyotropic liquid crystal, and then forming ordered arrangement liquid crystal-gel. The organagel and liquid crystal-gel can be used in catalysis, molecule switch, chemical sensing, drug delivery, drug segregation, specific optical device, and display unit and nanometer material mould.

The invention provides a phase-change material liquid and a solid-phase propping agent formed by the phase-change material liquid. The phase change material liquid is prepared from the following components in percentage by mass: 10-60 wt% of a super-molecule construction unit, 20-50 wt% of a super-molecule functional unit, 0.1-2 wt% of a dispersing agent, 0.1-1 wt% of an inorganic construction promoting agent, 0.1-1 wt% of an initiator and the balance of a solvent; the super-molecule construction unit comprises a melamine substance and / or a triazine substance; the super-molecule functional unit comprises dicyclopentadiene resin; and the dispersing agent comprises a hydroxyl-containing polysaccharide substance and a surfactant. After entering a reservoir, the phase-change material liquid can form a solid-phase substance to prop cracks under super-molecule chemical and physical action. Due to the injection of the non-solid phase, the string friction can be effectively reduced, and the requirements on construction equipment, ground surface pipelines, wellheads and operating tool strings are reduced. Therefore, the construction cost is effectively reduced, and the construction risk andthe potential safety hazard are reduced.

The invention relates to a carrier of non-virogene transfection, in particular to a cyclodextrin-polyethyleneimine material-mediated supramolecular delivery system, and aiming to provide a novel supramolecular delivery system for non-virogene treatment and medicine synergistic treatment. The supramolecular delivery system is formed through combining polyethyleneimine-cyclodextrin with adamantane-adriamycin by utilizing a self-assembly principle with the polyethyleneimine-cyclodextrin as a framework and the adamantane-adriamycin as a core. The supramolecular delivery system has the advantages that a self-assembled composite can reduce toxic and side effects of adriamycin, simultaneously improve the bioavailability of adriamycin and can carry out synergistic effect together with a gene carried by the polyethyleneimine-cyclodextrin.

A method of preparing low water-soluble medicine into solid nanometer pharmaceutical formulation is disclosed. According to the characters of molecular aggregates such as supramolecular chemical micelles and vesicles, the formulation, which based on the hydroxypropyl-beta-cyclodextrin and phospholipid, is prepared under the condition of hyperthermia sterilization and decompression. Such nanometer formulation is sterile particle or powder with loose porosity. For directly intravenous use, the formulation has targeting activity, sustained release and long circulating characters. While as a solid oral product, it is fast-release, fast-effective, and improved bioavailability characters, and is readily melted in mouth. The formulation utilizes secure accessories, traditional equipments and methods, thus, it is suited to be used and manufactured widely. Also disclosed is intravenous formulation of anticancer paclitaxel, which characterized that there has no polyoxyethylenated castor oil in it. Such intravenous formulation is nonallergic so that it has higher security and efficiency compared to present commercially available paclitaxel formulations.

The present invention discloses a method for including andrographolide by using cyclodextrin and its medicinal preparation. The andrographolide is an importent active extract of medicinal plant andrographis. Its inclusion method includes: adding 10-60g of cyclodextrin or its derivative into distilled water and dissolving it; adding 6g of andrographolide extract into 5-10 ml of medicinal methyl alcohol, heating and dissolving it; pouring the cyclodextrin aqueous solution into andrographolide ethyl alcohol solution; ultrasonic vibrating mixed solution in ultrasonic generator for 20-30 min., adopting thin-layer chromatography to identify the cyclodextrin-andrographolide inclusion quality. It does not change chemical property and effective activity of the andrographolide, can be prepared intovarious dosage forms.

The invention discloses a preparation method of peanut-oil-based plastic fat, which belongs to the field of combination of supramolecular chemistry and preparation technology of plastic fat for food. The method takes peanut oil, molecular distilled monoglyceride as raw materials. The method comprises the steps of mixing the raw materials according to a certain ratio, performing the procedures of heating, stirring, standing and cooling on the liquid-state peanut oil to obtain solid-state fat with certain plasticity, and respectively preparing the non-emulsified and emulsified peanut oil-based plastic fat. The preparation method is simple, mild in condition and low in cost, and the obtained plastic fat has the excellent properties of low trans acid and low saturated acid and has good application prospect.

The invention belongs to the field of supramolecular chemistry, and relates to dual-component micromolecular organic gels and a preparation method of the gels. The dual-component micromolecular organic gels comprise a first component which is a compound with one or a plurality of tetrazole groups, and a second component which can be various alkali compounds with amino, pyridine or imidazole groups; the first and second components are mainly subjected to intermolecular hydrogen bonding to form the gels; and the method for forming gel includes a heating method and an ultrasonic method. The gel factors can be used for immobilizing one or a plurality of common organic solvents to form stable gel, and also can form the gel under the commodity fuel solvent.

The invention discloses a preparation method of beewax-based plastic fat, belongs to the field of combination of a supramolecular chemistry technology and a plastic fat preparation technology for food, and in particular relates to a preparation method of low-saturation / low trans-fatty acid plastic fat. The method comprises the steps of: adding 3-16 percent of food-grade beewax which is benefit for human body into pure-liquid state low erucic acid colza oil ( or a oil-water mixture in a certain proportion); uniformly dissolving gel into grease under the conditions of heating at 80-100 DEG C, stirring at a rotation speed of 100-1,000rpm and homogenizing at 10-50MP; and cooling to a room temperature or a lower temperature at a cooling rate of 1-20 DEG C / min to obtain required plastic fat. The preparation method is simple, mild in conditions and low in cost; the content of the obtained grease saturated fatty acid is lower than 8 percent; the content of the trans-fatty acid is lower than 0.4 percent; and the physico-chemical property of the plastic fat is superior to vegetable shortening on the market, so that the plastic fat for food with high quality can be prepared individually or in a mode of compounding with other stearins.

The invention provides a carbazole-based high-condensed ring dinitrogen-aza[7]helicene compound (I) and a synthetic method thereof, belonging to the technical field of chemical industry. A high-condensed ring dinitrogen-aza[7]helicene compound with high solubility is prepared successfully by taking a cheap carbazole derivative with a plurality of active spots as a raw material by a photocatalysis loop closing method. The method has the advantages of high yield, short time, easiness for operating and the like; and moreover, the use of an expensive reagent is avoided, so that the preparation cost is reduced, and popularization and application are easy. The carbazole-based high-condensed ring dinitrogen-aza[7]helicene compound (I) is recrystallized in different solvents, so that an inclusion compound crystal comprising different solvents is obtained. The high-condensed ring dinitrogen-aza[7]helicene compound can be widely applied in the fields of super molecular chemistry, asymmetric catalysis, chiral liquid crystals, organic two-order nonlinearity, organic electroluminescence, biological medicine and the like.

The invention discloses a water-soluble poly gamma cyclodextrin-C60 supermolecule clathrate compound as well as a preparation method thereof, and relates to the technical field of supramolecular chemistry. The preparation method comprises the following steps of: placing the poly gamma cyclodextrin and fullerene C60 in ultrasonic treatment after mixing and stirring by using water as a solvent, and carrying out rotary evaporation until the mixture is thick; and then, obtaining the water-soluble poly gamma cyclodextrin-C60 supermolecule clathrate compound through vacuum-drying. The prepared clathrate compound contains a complex of 1wt%-50wt% of the poly gamma cyclodextrin, and concentration of the lathrate compound for dispersing the fullerene C60 in water is 10g / L. According to the invention, non-covalent bonds interact, water is used as the solvent, and the poly gamma cyclodextrin is used as a solubilizer, so that negative ion liquor pretreatment does not needed to be carried out onto C60, and the structure of the C60 is not damaged. The method disclosed by the invention is simple and convenient to operate, easily controllable in condition and capable of realizing industrialization.

The invention discloses a method for preparing an AA / AM / MAH-beta-CD ternary oil-displacing agent. Although a method for synthesizing a polymer through the cyclodextrin is utilized, but the method for synthesizing a copolymer through the maleic anhydride is not reported; because the cyclodextrin has special characteristics of external hydrophilic and internal lyophobic, the cyclodextrin is grafted to a polymer chain so that the viscosity of the polymer water solution is increased and the supramolecular chemistry is introduced into the petroleum industry. The method has the advantages that the method for synthesizing the unsaturated cyclodextrin monomer is simple, the temperature-resistant and the salt-resistant effect are obvious, the yield is high and the cost is low. The unsaturated cyclodextrin monomer is grafted to the copolymer chain through a simple method, the temperature-resistant and the salt-resistant research (the salt used in the experiment includes sodium chloride and calcium chloride) are processed, and the experiment result shows that the temperature-resistant and the salt-resistant property of the ternary copolymer are increased due to the introduction of the cyclodextrin.

The invention discloses a fluorenyl triangular-prism-shaped organic cage compound, and a preparation method and an application of the compound. The fluorenyl triangular-prism-shaped organic cage compound has a structure represented as a formula I shown in the description. The preparation method comprises performing cyclization on fluorenyl dimeric tertiary alcohol under a Friedel-Crafts reaction which is catalyzed by an acid to obtain the fluorenyl triangular-prism-shaped organic cage compound. The fluorenyl triangular-prism-shape organic molecular cage has a large cavity and specific surface area, has good solubility, good heat, electrochemistry and optics stability, and thus has wide application prospects in the fields of organic light emitting devices, molecular recognition, porous materials, supramolecular chemistry and the like.

The invention discloses a 6-site monosubstituted-beta-cyclodextrin functional monomer and a preparation method thereof, and belongs to the supramolecular chemistry and functional high-molecular polymer intermediate synthesis technical fields. The preparation method comprises the steps: with beta-cyclodextrin as raw material, firstly, deriving p-toluenesulfonyl chloride, synthesizing mono-(6-p-toluenesulfonyl-6-deoxy)-beta-cyclodextrin, then adopting ethylenediamine as a reaction reagent, synthesizing mono-(6-ethylenediamine-6-deoxy)-beta-cyclodextrin, finally adopting allyl glycidyl ether as a derivatization reagent, and synthesizing mono-(6-ethylenediamine-N-(2-(bis(3-allyloxy-2-hydroxy-propyl)))-(N-(3-allyloxy-2-hydroxy-propyl))-6-deoxy)-beta-cyclodextrin. The structure of mono-(6-ethylenediamine-N-(2-(bis(3-allyloxy-2-hydroxy-propyl)))-(N-(3-allyloxy-2-hydroxy-propyl))-6-deoxy)-beta-cyclodextrin synthesized by the method contains terminal vinyl, can be used as an extremely valuable functional monomer in high-molecular polymer preparation, and is used for selective molecular recognition of guest molecules.

The invention discloses a preparation method for a supramolecular graphene load ferroferric oxide self-assembly body, and belongs to the technical field of supramolecular chemistry. The method enables Fe3O4 to be disposed on the surface of graphene through the combination with the redox reaction of Fe3O4, thereby further improving the capacitive property. According to the invention, polyethylene glycol 2-adamantane is taken as a bridge agent, and then a supramolecular action force between cyclodextrin and adamantine molecules is employed. A prepared graphene @ ferroferric oxide three-dimensional assembly body not only solves a problem that the convergence of a graphene body causes the reduction of capacitance, but also greatly increases the specific capacitance which can reach 392.9 F / g, thereby indicating that the prepared graphene @ ferroferric oxide three-dimensional assembly body is good in application prospect for super-capacitors.

The invention discloses a method for reducing the viscosity of aqueous solution of hydrophobically associating polymer by using cyclodextrin. The cyclodextrin can be alpa-cyclodextrin, beta-cyclodextrin or gamma-cyclodextrin. The supramolecular chemical method for reducing the viscosity of the aqueous solution of hydrophobically associating polymer is simple, convenient and quick, has high pertinence, is slightly influenced by environment, ensures that a byproduct is not generated, and is an effective method for reducing the viscosity of polymer solution.

The invention belongs to the technical field of super-molecular chemistry and particularly relates to small molecule peptide-based cholesteric organic gel molecules and a preparation method thereof. The cholesteric organic gel molecules can form gel in an organic solvent and the formed gel has thermal stability and water stability and can respond to ultrasound for realizing transformation of ultrasonically-induced gel into gel. The organic gel molecule comprises 1) an anhydride naphthalene part serving as a luminophor, 2) a middle small peptide serving as a functional group for forming intermolecular hydrogen bonds and 3) a sterides part which has biocompatibility and serves as a gelation factor and a hydrophobic group. The molecule can form high-quality gel which has rich micro-nanoscale macro morphologies, such as nuclear shells, solid balls, defect balls, nanofiber, micro-fiber and the like, and has regular shape and high repeatability in nearly ten organic solvents including acetonitrile, ethanol, benzene, toluene, acetone and the like through a sol-gel process. The organic fluorescent gel has a certain application value in the aspects of nano material preparation, medicinal carrier transportation, biological marking and the like.

The present invention discloses a supramolecular microfiltration agent and a preparation method thereof. The chemical name of the supramolecular microfiltration agent is 1, 3, 5-hexahydrogen triazine sodium dithiocarbamate. The compound can react with complex heavy metal ions in waste water to generate supramolecular particles that can be easily eliminated through microfiltration. The chemical principles of supramolecular coordination are first applied to strengthen the microfiltration technology. And the present invention with low cost, high efficiency and little pollution can be used for treating the waste water with low-concentration heavy metal, in particular for deep treating the waste water with low-concentration complex heavy metal.

The invention belongs to the technical field of super molecular chemistry, and particularly relates to L-glutamine organogel containing 1-cyanotoluylene and a preparation method thereof. The organogel is a mixed system consisting of an organogel agent and a solvent. In the system, the organogel agent is L-glutamine organogel containing 1-cyanotoluylene, and the concentration of gel is 1-5 milligrams / milliliter. The organogel is obtained by dissolving a small molecular organogel agent in an organic solvent or a mixture of an organic solvent and water under a heating condition and cooling to room temperature. The organogel can be used for gelating 12 types of solvents such as toluene, chlorobenzol, dichlorobenzene, methylene dichloride, methanol, a mixture of DMSO (Dimethylsulfoxide) or DMF (Dimethyl Formamide) and water, and the like, and the system represents an aggregation induction fluorescence enhancement phenomenon in the gelating process. Due to the aggregation induction fluorescence enhancement property, the application of the L-glutamine organogel to a temperature-sensitive fluorescent switch becomes possible.

The invention belongs to the super-molecule chemistry field and specifically relates to a novel carbazole-based cyclophane. The structure formula of the novel carbazole-based cyclophane is shown in the specification, wherein n is greater than 0. The novel carbazole-based cyclophane is good in fluorescence and wide in application range, and can be used for constructing super-molecule sensors in the molecule identification field; and meanwhile, the cyclophane containing long-chain alkyl in the novel carbazole-based cyclophane can be taken as quaternary ammonium salt type surfactants and has potential application prospect in the field of surfactants.

The invention belongs to the technical field of supramolecular chemistry, and specifically relates to a preparation method and an application for an amphiphilic naphthoyl diimide gelator. The amphiphilic naphthoyl diimide gelator provided by the invention has a molecular formula of C89H138N4O21, and can enable benzene, toluene, xylene, dimethyl sulfoxide (DMSO) or a tetrahydrofuran solution with awater content of 30% (H2O-THF with a concentration of 30%) to generate gelation at a low concentration (3.3 mg.mL<-1> to 9.5 mg.mL<-1> through a heating-cooling method. Meanwhile, the molecular gel formed by gelation can realize reversible conversion between a solution state and a gel state through the external action of heating-cooling. The gelator provided by the invention has the advantages ofsimple synthesis, easily modified structure, thermal reversibility, large polarity range of a gelated solvent, etc., and has potential application values in fields like catalysis, sensor technologies, drug delivery and chiral separation.

A method for preparing a supra-molecular graphene load manganese dioxide self-assembly relates to the technical field of supra-molecular chemistry. According to the invention, the electrochemical performance of a graphene-based super capacitor is improved by combining the properties of a manganese dioxide Faraday capacitor and high specific surface area and high conductivity of graphene. Graphene-manganese dioxide compound is simply and rapidly prepared through supra-molecular interaction; then, graphene is assembled through supra-molecular interaction; and finally, a three-dimensional self-assembly of graphene sandwich manganese dioxide nanoparticles is obtained. Experiments show that the self-assembly of graphene load manganese dioxide has higher specific capacitance than that of pure manganese dioxide, and the specific capacitance can be up to 867.8 Fg<-1>.

The invention relates to a preparation method for a graphene self-assembly body for a super-capacitor based on supramolecular interaction, and relates to the technical field of supramolecular chemistry. The method comprises the steps: enabling cyclodextrin to be absorbed on the surface of graphene; adding polyethylene glycol 2-adamantane serving as bridge chain molecules, thereby achieving the self-assembly of graphene. The prepared graphene three-dimensional self-assembly body not only solves a problem that the graphene convergence causes small specific capacitance, and greatly increases the specific capacitance, thereby indicating that the graphene self-assembly body is good in application prospect for super-capacitors.

The invention discloses a high saline alkali reactive brilliant blue KN-RSR dye composition and a preparation method thereof, which belong to the technical field of reactive dyes, and solve the problem that reactive brilliant blue molecules are easily associated and hydrolyzed to separate out in the prior art. The high saline alkali reactive brilliant blue KN-RSR dye composition is a homogeneous mixture based on a complex synergism principle, and utilizes a supramolecular chemistry theory, so that the defect that the saline-alkaline resistance of reactive brilliant blue KN-RSR is poor under the condition of conventional dyeing is improved, meanwhile, the enhancement performance of dye is increased, and the dye composition has excellent leveling property and pile-onproperties; the high saline alkali reactive brilliant blue KN-RSR dye composition not only can be used for dyeing cheese and finished garment which have higher requirements on leveling property, but also can be applied in currently favored energy-saving and environment-protecting dyeing: cold padder dyeing.

The invention belongs to the field of supramolecular chemistry, and in particular relates to a coordination polymer gel (metal organic gel) formed based on tetrazole compounds and palladium acetate, and a preparation method of the metal organic gel. The framework of the tetrazole compounds comprise the structures of aryl, alkyl, porphyrin ring and the like; the tetrazole groups contain single tetrazole to four tetrazole; the tetrazole compounds and palladium acetate form irreversible metal organic gel in a solvent N,N-dimethylformamide or N,N-dimethylacetamide; and the tetrazole compounds do not have the characteristic of forming gel in the used solvent system. The used methyl tetrazole compound is the compound with minimal molecular weight, and the gel formed by the tetrazole compound and the palladium acetate is the simplest known coordination polymer gel at present.

The invention relates to the technical field of monatomic catalysis, in particular to a carbon-supported metal monatomic catalyst prepared based on cyclodextrin supramolecular chemistry in a controllable mode and a preparation method and application thereof.The carbon-supported metal monatomic catalyst comprises heteroatom-doped carbon serving as a carrier and metal monatomic anchored by the heteroatom-doped carbon, and the metal monatomic comprises Mo, Co, Ni, Fe, Pt, Ir, Au, Cu, Ru, Rh and Pd. According to the preparation method, cyclodextrin supermolecules are taken as a carbon source, a metal precursor is included in cavities of the cyclodextrin supermolecules by utilizing confinement and self-assembly effects of the cyclodextrin supermolecules, meanwhile, the cyclodextrin supermolecules and guest molecules containing heteroatoms are subjected to self-assembly, and the carbon-supported metal monatomic catalyst is prepared through high-temperature pyrolysis. The supramolecular self-assembly confinement pyrolysis method adopted by the invention is simple in preparation method, free of metal loss, free of pollution emission, green in synthesis and high in metal monatomic loading capacity.

The invention belongs to the supermolecule chemical technology field, more particular, relates to a low molecular weight organogel and a preparing method of the low molecular weight organogel. The low molecular weight organogel of the invention is prepared by dissolving a low molecular weight organogel agent in an organic solvent under heating, and then cooling to the ambient temperature or a low temperature (wherein the heating temperature is lower than the boiling point of the organic solvent; the cooling temperature is higher than the freezing point of the organic solvent); wherein, the concentration of the low molecular weight organogel agent in the organic solvent is 0.1wt%-10wt%.

A tetra(4-triazolephenyl) pentaerythritol ether single crystal and a preparing method thereof are disclosed. The tetra(4-triazolephenyl) pentaerythritol ether single crystal is prepared by adopting a "one-pot" method, namely by heating p-bromophenyl pentaerythritol ether, triazole, potassium carbonate and copper oxide to obtain the organic compound. The preparing method has characteristics of simple process operation, low production cost and low environment pollution, and is suitable for large-scale industrial production. The prepared single crystal can be applied in the field of research on supramolecular chemistry and fire retardants.