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46 results about "Aloe Polysaccharide" patented technology

Aloe polysaccharides comes from the aloe vera plant and is used for skin-wound healing.. Hydrocortisone is a steroid. It prevents the release of substances in the body that cause inflammation. Iodoquinol is an antibiotic and antifungal medication that fights infection caused by bacteria or fungus.. The combination of aloe polysaccharides, hydrocortisone, and iodoquinol topical (for the skin ...

Application of aloe polysaccharide in regulation and control of energy metabolism of mitochondria

The invention discloses application of aloe polysaccharide in regulation and control of mitochondrial energy metabolism, and belongs to the field of new application of aloe polysaccharide. The aloe polysaccharide can regulate mitochondrial energy metabolism to be converted into anabolism, promote the content of protein and amino acid in cells and promote wound healing. The preparation method of the aloe polysaccharide comprises the following steps: removing two ends of fresh aloe barbadensis leaves, and soaking the fresh aloe barbadensis leaves with pure water for 1-2 days; washing with water and removing skin to obtain aloe gel to be ground; shearing the aloe vera gel to be ground in an automatic gel grinding device to finish gel grinding, so as to obtain aloe polysaccharide feed liquid; and putting the aloe polysaccharide feed liquid into a stirring tank, stirring at 4-15 DEG C, carrying out light treatment for at least 24 hours, and then collecting the aloe polysaccharide pervaporation membrane on the surface of the liquid in a high-temperature membrane forming tank at 75-95 DEG C, thereby obtaining the aloe polysaccharide pervaporation membrane.
Owner:广州市东源药业科技有限公司 +1

High-efficiency mild unhairing cosmetic and preparation method thereof

The invention relates to the technical field of cosmetics, and discloses a high-efficiency mild depilation cosmetic and a preparation method thereof, and the raw materials of the depilation cosmetic comprise, by weight, 8-10% of bromelain; 10%-12% of a turmeric root extract; 9%-11% of a calendula extract; 6%-9% of an aloe extract; 4%-7% of a soybean extract; 7%-10% of calcium thioglycolate; 2%-5% of L-cysteine; 1%-3% of sodium bicarbonate; 3%-6% of green tea polyphenol; 2%-4% of a chamomile extract; 1%-3% of dipotassium glycyrrhizinate; 0.9%-2.3% of a peptide component; 0.5%-1% of rosmarinic acid; 1%-3% of vitamin E; 2%-4% of gluconic acid; 4%-5% of beewax; 5%-10% of an emulsifier; according to the invention, dipotassium glycyrrhizinate and the chamomile extract form a dual anti-allergy barrier, the physical protection effect of aloe polysaccharide is combined to reduce skin irritation, and the turmeric root extract and the peptide component prolong the hair follicle resting period and reduce the hair regeneration rate, so that the safer and more effective hair removal cosmetic is prepared.
Owner:GUANGZHOU YUNMEI COSMETICS CO LTD

Skin-friendly organopolysiloxane elastomer material and preparation method thereof

The invention discloses a skin-friendly organopolysiloxane elastomer material and a preparation method thereof, and relates to the technical field of organosilicon materials. The preparation method of the skin-friendly organopolysiloxane elastomer material at least comprises the following preparation steps: dissolving a hydrophilic modified polysiloxane elastomer in chloroform, pouring into a mold, and drying to obtain a supporting layer; the aloe polysaccharide modified polysiloxane copolymer is dissolved in a tetrahydrofuran / water mixed solvent, the mixture is smeared on the supporting layer, a contact layer is formed after drying, and the skin-friendly organopolysiloxane elastomer material is obtained. The skin-friendly organopolysiloxane elastomer material prepared by the invention has good mechanical properties, air permeability and water absorption, is beneficial to growth and regeneration of wound tissues when being used as a dressing, and accelerates healing of wounds.
Owner:NINGBO ECONOMIC TECH DEV ZONE QINGHUI PLASTIC IND CO LTD

Multi-effect analgesic and anti-inflammatory gel for oral cavity and preparation method thereof

The invention discloses oral multi-effect analgesic and anti-inflammatory gel and a preparation method thereof, and belongs to the technical field of medical gel. The gel is prepared from mussel mucin grafted hydroxypropyl chitosan, a poly (N-isopropylacrylamide)-co-acrylic acid copolymer, quercetin-zinc coordination nanoparticles, a local anesthetic compound wrapped by temperature-sensitive lipidosome, a gamma-polyglutamic acid-catechin gel matrix, aloe polysaccharide, dipotassium glycyrrhizinate, and sodium hyaluronate and potassium sorbate which can be selectively added, wherein the local anesthetic compound is prepared from the mussel mucin grafted hydroxypropyl chitosan, the poly (N-isopropylacrylamide)-co-acrylic acid copolymer, the quercetin-zinc coordination nanoparticles, the temperature-sensitive lipidosome, the gamma-polyglutamic acid-catechin gel matrix, the aloe polysaccharide and the dipotassium glycyrrhizinate. During preparation, part of the components and water are stirred to obtain a mixed solution, and then the other components are added and stirred into gel. According to the gel, the leakage rate of local anesthetics is reduced by stabilizing the liposome through the zinc ions, the quercetin adjusts the phase transition temperature of the liposome to realize preferential drug release at the pain part, the mussel mucin and the copolymer form a reversible hydrogen bond network to enhance the mucous membrane adhesive force, and the inflammatory environment triggers the gel permeation drug release, so that the gel has the advantages of multiple-effect synergy, strong adhesion and the like; the problems that existing oral gel is short in analgesia time and insufficient in anti-inflammation can be effectively solved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

Method for detecting aloe polysaccharide effective component in aloe raw material

This application relates to the field of chemical analysis technology, specifically to a method for detecting the effective components of aloe polysaccharides in aloe vera raw materials. The method includes: obtaining a chromatogram of an aloe vera sample hydrolysate; determining the chromatographic peak corresponding to acetic acid from multiple chromatographic peaks based on the retention time and peak shape characteristics of each chromatographic peak; determining the amount of acetic acid in the aloe vera sample hydrolysate based on the hydrolysis completeness at a current moment and the peak area of ​​the chromatographic peak corresponding to acetic acid at that current moment, wherein the hydrolysis completeness at a given moment is used to characterize the degree of hydrolysis of the aloe vera sample at that moment; and determining the content of the effective polysaccharide components in the aloe vera sample based on the amount of acetic acid. This method can obtain an accurate amount of acetic acid, and based on this accurate amount of acetic acid, the content of the effective polysaccharide components in the aloe vera sample can be accurately detected.
Owner:SHANXI AGRI UNIV

Novel beverage and preparation method thereof

The invention relates to a novel beverage and a preparation method thereof. Comprising the following components in percentage by weight: 0.05%-0.6% of a double-petal red rose distillation extracting solution, 0.05%-0.6% of food-grade hyaluronic acid, 0.05%-0.6% of xylitol or erythritol, 0.1%-0.3% of a butterfly bean flower extracting solution, 0.05%-0.2% of a turmeric root extracting solution, 0.03%-0.1% of mint leaf essence, 0.1%-0.4% of chia seed powder, 0.2%-0.5% of aloe juice, 0.1%-0.3% of a pomegranate extracting solution, 0.05%-0.2% of a green tea extracting solution, 0.02%-0.1% of citric acid and the balance of water. Hyaluronic acid and rose hydrolat are added, so that the oral liquid has the effects of moisturizing, resisting aging, soothing liver-qi stagnation and relieving and reducing pressure after being orally taken, aloe polysaccharide and chia seeds form a stable colloidal network, satiety and skin repair capacity are improved, low sugar and low burden are achieved, pomegranate ellagic acid has the effects of resisting inflammation, natural color matching with butterfly bean flowers is achieved, visual interest is enhanced, green tea catechin and curcumin are compounded to resist oxidation, promote metabolism and strengthen immunity, and the oral liquid has the effects of promoting metabolism and improving immunity. And the defects of irritation, single nutrition and the like of the traditional beverage are overcome.
Owner:HONGHE NATURE WATER IND CO LTD

Application of aloe polysaccharide in improving solubility and storage stability of insoluble substances

The invention discloses application of aloe polysaccharide to improvement of solubility and storage stability of insoluble substances. The aloe polysaccharide can be used as a solubilizer of insoluble substances, and the preparation method of the aloe polysaccharide comprises the following steps: removing two ends of fresh aloe barbadensis leaves, and soaking the fresh aloe barbadensis leaves in pure water for 1-2 days; washing with water and removing skin to obtain aloe gel to be ground; the aloe gel to be ground is ground, and aloe polysaccharide feed liquid is obtained; and putting the aloe polysaccharide feed liquid into a stirring tank, stirring at 4-15 DEG C, carrying out light treatment for at least 24 hours, and then collecting the aloe polysaccharide pervaporation membrane on the surface of the liquid in a high-temperature membrane forming tank at 75-95 DEG C, thereby obtaining the aloe polysaccharide pervaporation membrane. According to the present invention, the aloe polysaccharide pervaporation membrane can be used for improving the solubility and the stability of the insoluble substance (such as fumaric acid) at the normal temperature so as to avoid the storage precipitation;
Owner:广州市东源药业科技有限公司 +1

Medical dressing and preparation method thereof

The invention discloses a medical dressing and a preparation method thereof. The dressing is prepared from the following components in parts by weight: 30 to 100 parts of sodium carboxymethyl cellulose, 30 to 50 parts of polyethylene glycol, 30 to 50 parts of sodium alginate, 20 to 30 parts of sodium hyaluronate, 5 to 15 parts of a humectant, 3 to 8 parts of a plant extract, 2 to 6 parts of compound polysaccharide, 0.01 to 0.5 part of a growth factor, 0.2 to 0.6 part of balanophora balanophora, 0.1 to 0.5 part of ginsenoside Rg1 and 300 to 600 parts of deionized water. The medical dressing disclosed by the invention is good in antibacterial and anti-inflammatory effects and has a certain repairing effect on scars. The termitomyces albuminosus extract and the callicarpa bodinieri extract in the components are combined for use, so that the antibacterial effect is enhanced; the rosa roxburghii tratt polysaccharides and the aloe polysaccharides are combined to resist inflammation and promote wound healing; balanineine and ginsenoside Rg1 are combined for use to inhibit scar generation.
Owner:北京明启生物科技有限公司

Use of aloe pulp powder or active ingredients thereof in the preparation of a drug for treating depression

The application belongs to the field of traditional Chinese medicines, and discloses application of aloe pulp powder in preparation of a medicine for treating depression, wherein the aloe pulp powder is a dehydrated solid powder obtained by peeling off the whole leaves of aloe. The inventors construct a mouse depression model by using CUMS, and show that the aloe pulp powder can significantly improve the moving distance of the model mice in an open field experiment and the immobile time of the model mice in a tail suspension test and a forced swimming test, and exhibits significant antidepressant activity. The application also discloses application of at least one of aloe polysaccharide, aloe flavone or aloe polyphenol in preparation of a medicine for treating depression. The aloe polysaccharide, the aloe flavone and the aloe polyphenol all have the efficacy of treating depression, and the efficacy of polysaccharide > the efficacy of flavone > the efficacy of polyphenol. The application further discloses a composition for treating depression, which is a composition of aloe polysaccharide, aloe flavone and aloe polyphenol in a mass ratio of 6.945-31.432:1.185-32.146:0.251-14.323.
Owner:HAINAN ENNEAS TECHNOLOGY LTD

Low-sensitivity high-taste nicotine buccal preparation and preparation method thereof

The invention provides a low-sensitivity and high-taste nicotine buccal preparation and a preparation method thereof. The nicotine buccal preparation comprises an inner layer, a middle layer and an outer layer, wherein the middle layer and the outer layer sequentially coat the inner layer from inside to outside; the outer layer comprises nicotine salt, a plant source carrier and a film-forming agent; the components of the middle layer comprise nicotine salt and a hydrophilic high polymer material; the inner layer comprises nicotine salt, silicon dioxide nanoparticles, a plant source carrier and a film-forming agent; the plant source carrier comprises any one or a combination of at least two of aloe polysaccharide, inulin or pea protein peptide. Through design and compatibility of a three-layer composite structure, the release rate and the release amount of nicotine are cooperatively controlled and controlled within a reasonable range, and the nicotine sustained release tablet has relatively low oral irritation and relatively high taste characteristics, can meet instant requirements and maintenance requirements of nicotine and ensure fresh breath, and is suitable for people with sensitive oral cavities and social scenes.
Owner:CHINA TOBACCO JIANGSU INDAL

PH self-adaptive private care lotion based on composite biological bacteriostatic system and preparation method

The invention discloses a pH self-adaptive private care lotion based on a composite biological antibacterial system. The pH self-adaptive private care lotion is prepared from 8 to 12 parts of cocamidopropyl betaine, 0.5 to 1.5 parts of polylysine hydrochloride, 0.3 to 0.8 part of tea tree essential oil, 1.2 to 2.0 parts of lactic acid-sodium lactate buffer agent, 0.1 to 0.3 part of dipotassium glycyrrhizinate, 0.5 to 1.2 parts of chamomile extract, 0.3 to 0.7 part of lactobionic acid, 1.0 to 2.0 parts of aloe polysaccharide and the balance of deionized water. During preparation, the tea tree essential oil and beta-cyclodextrin are subjected to clathration for 30 minutes at 35 DEG C to form a clathrate compound, so that the volatile loss is reduced by 80%; dissolving polylysine hydrochloride in deionized water at 4 DEG C, and adding a lactic acid-sodium lactate buffer solution; lactobionic acid and a chamomile extract are added; homogenizing for 3 minutes by using a homogenizer at the speed of 2000rpm; and carrying out vacuum defoaming under 0.08 MPa. Dynamic pH buffering is achieved, and a lactic acid-lactobionic acid double-buffering layer resists secreta impact; a preservative-free process is adopted, and vacuum defoaming and PES membrane filtration are used for replacing chemical preservatives; and gender differentiation adaptation: cranberry polyphenol, female adhesion prevention and succinic acid buffer male pH adaptation.
Owner:MIAOWANG PHARMACEUTICAL (GUANGZHOU) CO LTD

Method for determining free mannose and total mannose in biological sample based on LC-MS / MS (Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) method

The invention belongs to the technical field of analytical chemistry, and particularly relates to a method for determining free mannose and total mannose in a biological sample based on an LC-MS / MS (Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) method. According to the method provided by the invention, endogenous mannose and exogenous mannose of a biological sample can be distinguished, and the existence form (monosaccharide or polysaccharide) of mannose introduced into aloe polysaccharide is further identified. The method has the advantages of simplicity and convenience in operation, high specificity, high sensitivity, good precision and accuracy and the like, not only overcomes the limitation of insufficient sensitivity of HPLC and spectrophotometry, but also meets the requirements of respective detection of monosaccharide and polysaccharide in a biological sample.
Owner:GUANGDONG LEWWIN PHARM RES INST CO LTD

Medical silicone gel for scar repair and preparation method and application thereof

The invention discloses medical silicone gel for scar repair and a preparation method and application thereof, and relates to the technical field of medical gel. The aloe polysaccharide silicone gel mask comprises the following raw materials in percentage by mass: 25-45% of aloe polysaccharide silicone gel, 1-2% of sodium hyaluronate, 0.2-0.8% of poly-L-lactic acid, 2-4% of vitamin E, 5-8% of asiaticoside, 1-3% of resveratrol, 1-2% of curcumin, 1-2% of hydroquinone, 2-4% of arbutin, 2-4% of a vitamin C derivative, 3-5% of a traditional Chinese medicine composition, 0.5-1.5% of an odor regulator, 0.1-0.3% of a preservative and the balance of water. And the balance of purified water. The smell regulator is a pH response release type adsorbent. The medical silicone gel not only can effectively repair scars, but also is good in skin feeling and not prone to sensitivity.
Owner:HUBEI DICHEN BIOTECHNOLOGY CO LTD

Extraction method of aloe polysaccharide

PendingCN121319240AFiberCrude fibre
The invention provides an extraction method of aloe polysaccharide, and belongs to the technical field of extraction of chemical components of aloe. The preparation method comprises the following steps: peeling aloe vera, dicing, soaking in cold water, stirring and crushing to form aloe juice; further heating the aloe juice to homogenize the aloe juice; filtering to remove crude fibers after homogenization, adding granular active carbon into the filtrate for decoloration, filtering to obtain a clear solution, adding ammonia water into the solution, and adjusting the pH value to be alkaline; continuously heating and concentrating the obtained clear solution; adding ethanol into the concentrated solution, adding an ammonium chloride coagulant, standing and precipitating; and centrifugally separating the obtained mixture with the precipitate, and washing and drying the obtained precipitate to obtain the aloe polysaccharide. Compared with a traditional extraction process, the aloe polysaccharide extraction method has the advantages that the process flow is simple, the process condition control operability is high, and the extraction rate of the aloe polysaccharide in the separation process is high. An experiment result shows that the extraction rate of the aloe polysaccharide is up to 11.23% and is obviously higher than that of the traditional extraction process.
Owner:EAST CHINA UNIV OF TECH

A kind of dynamic covalent hydrogel dressing of aconite leaf nanoparticles and its preparation and application

This invention relates to the field of pharmaceutical technology, specifically to a dynamic covalent hydrogel dressing loaded with moxa nanoparticles, its preparation method, and its application. The dynamic covalent hydrogel dressing loaded with moxa nanoparticles is composed of a dispersion of moxa nanoparticles made from moxa, aloe polysaccharides, and tea saponins, and a hydrogel matrix made from chitosan, polyvinyl alcohol, ε-polylysine, and 4-formylphenylboronic acid. This invention provides a multifunctional traditional Chinese medicine nanocomposite hydrogel dressing integrating intelligent response, antibacterial membrane-breaking, antioxidant, cell repair promotion, and wound healing promotion. It can provide a safe, efficient, and targeted novel solution for the clinical treatment of deep burns complicated with drug-resistant bacterial infections, and provides an experimental basis and technical reference for the formulation development and application of active ingredients of traditional Chinese medicine in wound repair.
Owner:GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE

Multifunctional cotton fabric finishing process based on plant extract microcapsules

PendingCN120537134AVegetal fibresGreen Tea PolyphenolsPhenolic content in tea
The invention provides a multifunctional cotton fabric finishing process based on plant extract microcapsules, and belongs to the technical field of textile processing.The multifunctional cotton fabric finishing process comprises the steps that microcapsule powder and a cross-linking agent are added into water, the pH is adjusted to be acidic, and steeping liquor is obtained; the cotton fabric is subjected to two-time dipping and two-time rolling in the dipping liquid; taking out the cotton fabric, pre-baking, baking, washing with water, soaping, and drying at 80 DEG C for 10 minutes to obtain the multifunctional cotton fabric based on the plant extract microcapsules. Core material components of the microcapsule powder are wormwood extract, green tea polyphenol, aloe polysaccharide and citric acid modified soybean protein, wall material components of the microcapsule powder are chitosan and sodium alginate, the mass ratio of the chitosan to the sodium alginate is 3: 1, and the finished cotton fabric is suitable for medical textiles, household fabrics (such as outdoor clothes) and infant textiles and is wide in application range.
Owner:GUANGDONG VOCATIONAL & TECHNICAL COLLEGE +1

Chloroplast storage liquid and application thereof

PendingCN121942677AEffectively maintain activityDead plant preservationFermentationBiotechnologyGlycan
The invention provides chloroplast storage liquid and application thereof. The chloroplast storage solution disclosed by the invention is prepared from the following components in parts by mass: 5 to 30 parts of aloe polysaccharide ABPA1, 5 to 30 parts of aloe acetylmannan ABPA2, 2 to 15 parts of red algae colloid extract and 25 to 88 parts of water. The invention also provides an application method of the chloroplast storage liquid. According to the chloroplast storage solution, the plant polysaccharide and the red algae colloid extract are applied to an in-vitro chloroplast storage system, so that the activity of chloroplast can be effectively maintained for a long time, and a stable and reliable in-vitro research window is provided for deeply analyzing a fine mechanism of photosynthesis; moreover, it is possible to serve as a high-efficiency biological light energy converter.
Owner:东源药业科技(昆明)有限公司 +1

Low-irritation double-layer gel anesthetic for urethra and preparation method of low-irritation double-layer gel anesthetic

The invention provides a urethra low-irritation double-layer gel anesthetic and a preparation method thereof.The anesthetic comprises a first gel layer, a second gel layer and a third gel layer, the first gel layer comprises a local anesthetic and a temperature-sensitive reversible gel matrix, and the temperature-sensitive reversible gel matrix is subjected to sol-gel transition at 25-40 DEG C; the second gel layer comprises aloe polysaccharide and an irreversible gel skeleton, and the irreversible gel skeleton is formed by a polysaccharide gel agent; wherein the first gel layer and the second gel layer are physically compounded at an interface to form a double-layer whole. According to the double-layer gel anesthetic, the local anesthetic and the temperature-sensitive reversible gel matrix are compounded, gel can be rapidly formed under the body temperature condition, it is guaranteed that the drug fully stays and slowly releases in the local part of the urethra, and the anesthetic effect is remarkably improved.
Owner:CHINA PHARM UNIV PHARM CO LTD

High-moisture-retention cosmetic contact lens material based on natural raw materials and low-irritation preparation method of high-moisture-retention cosmetic contact lens material

The invention relates to the technical field of contact lens materials, in particular to a high-moisturizing cosmetic contact lens material based on natural raw materials and a low-irritation preparation method thereof.The high-moisturizing cosmetic contact lens material is prepared from, by mass, 25%-38% of hyaluronic acid-chitosan compound, 12%-22% of plant extract and 6%-12% of natural moisturizing factors; 0.3%-1.5% of a natural cross-linking agent, and the balance deionized water with the conductivity less than or equal to 1 [mu] S / cm; the mass ratio of hyaluronic acid to chitosan in the hyaluronic acid-chitosan compound is (3: 1)-(5: 1); the plant extract comprises a mixture of aloe polysaccharide and seaweed gel, and the mass ratio of the aloe polysaccharide to the seaweed gel is (2: 1)-(4: 1); the natural moisturizing factor comprises a mixture of glyceryl laurate and betaine in a mass ratio of (1: 1)-(2: 1). Natural synergistic moisturizing is realized through electrostatic net formation of the hyaluronic acid-chitosan compound and combination of aloe polysaccharide and mucoprotein, glutaraldehyde is replaced by genipin, a low-irritation process is realized through dialysis and impurity removal, and the effects of high moisturizing, low irritation, good oxygen permeability and good biocompatibility are realized by combining a double-layer structure and natural moisturizing factors.
Owner:HANGZHOU MEILI TONGXIN E-COMMERCE CO LTD

Active delivery microcapsules, methods of making and using the same

The application provides an active substance delivery microcapsule, a preparation method and application thereof, a wall material of the active substance delivery microcapsule comprises polylysine, plant polysaccharide and polyethylene glycol; the plant polysaccharide comprises any one or a combination of at least two of bletilla striata polysaccharide, aloe polysaccharide, dendrobium polysaccharide, tremella polysaccharide, seaweed polysaccharide, medlar polysaccharide, tricholoma matsutake polysaccharide and ganoderma polysaccharide or beta-glucan; and a core material of the active substance delivery microcapsule comprises an active substance. Wall material components form a dense and stable high-molecular crosslinked network through electrostatic interaction and hydrogen bond interaction, significantly improve the efficacy stability of the active substance of the core material, and play excellent skin care efficacy.
Owner:GUANGZHOU RIDGEPOLE BIOLOGICAL TECH CO LTD

A method for improving the content of aloe polysaccharide in aloe products by using an electric field

The application provides a method for improving the content of aloe polysaccharide in aloe products by using an electric field, and relates to the technical field of biological pharmacy. The method for improving the content of aloe polysaccharide in aloe products can control the content of biological macromolecular polysaccharide generated by polymerization reaction by adjusting appropriate current and electric field treatment time, thereby successfully improving the content of aloe polysaccharide in aloe vera gel by using an external electric field. Since aloe polysaccharide is the main active ingredient in aloe, its content is very important, therefore, the method for improving the content of aloe polysaccharide in aloe products has important significance for the development of the medicinal value of aloe polysaccharide products, and has important value for improving the polysaccharide yield and reducing the unit cost of polysaccharide.
Owner:东源药业科技(昆明)有限公司

Active substance for repairing intestinal mucosal barrier of dog as well as preparation method and application of active substance

The invention discloses an active substance for repairing canine intestinal mucosal barrier and a preparation method and application thereof, and relates to the technical field of animal health care products. The composition comprises one or more of centella asiatica extract, aloe polysaccharide, ginkgo biloba extract, glutamine, beta-glucan, vitamin B6, vitamin B2 and the like, and the components jointly act on oxidative stress, inflammatory response and metabolic process of canine intestinal tracts. By measuring indexes such as inflammatory factors, oxidative stress and tight junction protein and combining in-vitro metabonomics and transcriptomics analysis, the pharmaceutical composition has remarkable effects in the aspects of oxidation resistance, inflammation resistance, mucosal barrier repair and the like. In addition, the invention also provides application of the active substance in preparation of food for repairing dog intestinal mucosa. Compared with the prior art, an effective health-care strategy can be provided, and the intestinal mucosal barrier of the dog can be remarkably repaired.
Owner:WUHU WEISHI BIOTECHNOLOGY CO LTD +3

Method for detecting effective components of aloe polysaccharide in aloe raw material

The invention relates to the technical field of chemical analysis, in particular to a method for detecting effective components of aloe polysaccharide in an aloe raw material, and the method comprises the following steps: acquiring a chromatogram of aloe sample hydrolysate; based on the peak retention time and the peak shape characteristic of each chromatographic peak, determining a chromatographic peak corresponding to acetic acid from the plurality of chromatographic peaks; based on the hydrolysis completeness at the current moment and the peak area of the chromatographic peak corresponding to the acetic acid at the current moment, the amount of the acetic acid in the aloe sample hydrolysate is determined, and the hydrolysis completeness at one moment is used for representing the hydrolysis degree of the aloe sample at the moment; and determining the content of polysaccharide active ingredients in the aloe sample based on the acetic acid amount. According to the method, the accurate acetic acid amount can be obtained, and based on the accurate acetic acid amount, the content of polysaccharide active ingredients in the aloe sample can be accurately detected.
Owner:SHANXI AGRI UNIV

Application of phagocytic macrophages for in-vitro regulation and control of aloe polysaccharide in promotion of wound healing

The invention discloses an application of phagocytic macrophages regulated and controlled in vitro by aloe polysaccharide in promoting wound healing. According to the present invention, the aloe polysaccharide pervaporation membrane can be used for preparing phagocytic macrophages, the aloe polysaccharide pervaporation membrane is added into the macrophage culture medium, the result shows that the phagocytic ability of the macrophages is significantly improved, and the further experiment shows that the phagocytic macrophages are used for wound treatment, the inflammation level of the wound is obviously inhibited, and the healing speed of the wound is increased.
Owner:广州市东源药业科技有限公司 +2

Natural plant polyphenol alcohol-free washing-free gel and preparation method thereof

The invention provides a natural plant polyphenol alcohol-free wash-free gel and a preparation method thereof, and the natural plant polyphenol alcohol-free wash-free gel is prepared by mainly using natural plant polyphenol extracted from red raspberry leaves, dandelion flowers and pomegranate rind as a bacteriostatic agent and embedding the extracted natural plant polyphenol by using a polylactic acid-polyethylene glycol copolymer. The preparation method comprises the following steps: (1) raw material pretreatment, (2) polyphenol extraction, (3) polyphenol microsphere suspension preparation, (4) polyphenol microsphere collection, (5) aloe polysaccharide extract preparation, and (6) no-wash gel preparation. The invention provides a new path for high-valued utilization of agricultural and sideline products and upgrading of natural polyphenol industry, endows the gel with high efficiency and broad-spectrum antibacterial performance, avoids irritation of alcohols to skin, eliminates flammable hidden danger of alcohols, and can be used in places such as airports and stations. The stability of the polyphenol is remarkably improved and the shelf life is prolonged through copolymer embedding, long-acting bacteriostasis is achieved, and the hydrogel has good biocompatibility and wide market prospects.
Owner:NORTHEAST FORESTRY UNIV

Method for improving stability of aloe polysaccharide microsphere emulsion

PendingCN122356520ARos scavengingEmulsion
The application discloses a method for improving the stability of aloe polysaccharide microsphere emulsion. The method adds a specific parameter water bath ultrasonic treatment step on the basis of the existing aloe polysaccharide microsphere emulsion preparation process. The aloe polysaccharide microsphere emulsion is placed in an ultrasonic generator, purified water is added as a conducting medium, ultrasonic waves with a frequency of 35-45 kHz and a power of 200-300 W are used for water bath ultrasonic treatment, the treatment time is 0.5-3 hours, and the ultrasonic water temperature is controlled to be 45-55 DEG C. The method can significantly reduce the microsphere particle size, increase the microsphere quantity, and improve the absolute value of the surface potential, thereby improving the long-term storage stability of the emulsion. Meanwhile, the emulsion after treatment shows stronger ATP synthesis recovery, mitochondrial membrane potential stability and ROS scavenging capacity at the cell level, and has enhanced cell protection efficacy.
Owner:广州市东源药业科技有限公司 +1

Lung anti-inflammatory spray based on aloe polysaccharide and preparation method thereof

The invention relates to the technical field of medicines, and discloses a lung anti-inflammatory spray based on aloe polysaccharide, which realizes efficient anti-inflammatory (IL-6) and targeted delivery (deposition rate of 85%) by optimizing the proportion of natural components (8% of aloe polysaccharide, 1.5% of dipotassium glycyrrhizinate and 2% of andrographolide) and an atomization process (particle size of 2 mu m). According to the lung anti-inflammatory spray based on the aloe polysaccharide and the preparation method of the lung anti-inflammatory spray, through the synergistic effect of the aloe polysaccharide (8%) and natural anti-inflammatory components (1.5% of dipotassium glycyrrhizinate and 2% of andrographolide), the proinflammatory factor level (IL-6 is reduced by 60%, and TNF-alpha is reduced by 62%) is remarkably reduced, the inhibition rate on an LPS-induced mouse pneumonia model reaches 88% or above, and the lung anti-inflammatory spray has the advantages that the lung anti-inflammatory spray has a good application prospect. The effect of the dexamethasone spray is better than that of a single-component or chemically synthesized drug (such as dexamethasone), drug particles are efficiently deposited in an alveolar area through an optimized atomization process (the spraying particle size is 2 microns), the lung deposition rate is larger than or equal to 85% and far exceeds that of a conventional spray (generally smaller than or equal to 70%), and the bioavailability is remarkably improved.
Owner:SHANGHAI PULMONARY HOSPITAL (SHANGHAI OCCUPATIONAL DISEASE PREVENTION & CONTROL INSTITUTE) +1

High-moisture-retention antibacterial silicone hydrogel contact lens material and preparation method thereof

The invention relates to the technical field of preparation of contact lens materials, and particularly discloses a high-moisture-retention and antibacterial silicone hydrogel contact lens material and a preparation method thereof.The high-moisture-retention and antibacterial silicone hydrogel contact lens material is prepared through the following steps that S1, a silicon-containing component is prepared; s2, preparing a hydrogel contact lens material; the antibacterial dispersion liquid is added, the antibacterial dispersion liquid contains a sodium alginate structure, a chlorogenic acid structure, zinc glycinate and an aloe extract, on one hand, active hydroxyl contained in the molecular structure of the sodium alginate can be combined with water molecules through hydrogen bonds, and on the other hand, the active hydroxyl serves as an anchoring point to be subjected to esterification reaction with carboxyl of chlorogenic acid, so that the antibacterial effect is achieved. The zinc glycinate is used as a source of organic zinc, and the aloe extract is rich in aloe polysaccharide and anthraquinone compounds, so that the moisture retention, oxygen permeability and antibacterial property of the hydrogel contact lens material can be improved by introducing the aloe extract into the hydrogel contact lens material.
Owner:IRIS (XIAMEN) TECH CO LTD

Extraction method of aloe polysaccharide and application of aloe polysaccharide in cigarettes

PendingCN121800961ATobacco treatmentPhysical chemistryTetramethylammonium chloride
The invention relates to the technical field of aloe polysaccharides, and provides an extraction method of aloe polysaccharides and application of the aloe polysaccharides in cigarettes, the extraction method of the aloe polysaccharides comprises the following steps: S1, peeling, crushing and filtering aloe to obtain aloe juice and filter residues; s2, adding the aloe juice into a deep-eutectic solvent, performing ultrasonic extraction, and filtering to obtain an extracting solution; s3, concentrating the extracting solution, adding absolute ethyl alcohol, uniformly mixing, standing, filtering and drying to obtain aloe polysaccharide; the eutectic solvent comprises a substance A and a substance B; the substance B comprises tetramethylammonium chloride; the substance A comprises resorcinol. According to the technical scheme, the problems of insufficient extraction rate and purity of the aloe polysaccharide in the prior art are solved.
Owner:CHINA TOBACCO HEBEI INDUSTRIAL CO LTD