168 results about "Hydroxypropyl Chitosan" patented technology

The medical chitosan dressing is mixture of chitosan in 1 weight portion, Chinese medicine extract in 0.01-10 weight portions, chitosan derivative in 0.01-10 weight portions, and metal ion in 0.0001-0.05 weight portion. The Chinese medicine extract is bletilla tuber polysaccharide or natural indigo; and the chitosan derivative is one of hydroxypropyl chitin, hydroxypropyl chitosan, succinyl chitin, succinyl chitosan, carboxymethyl chitin and carboxymethyl chitosan. The medical chitosan dressing has the functions of promoting healing of the wound and stopping bleeding, inhibiting bacterial growth, and has excellent wound pasting performance.

The invention relates to a preparation process of a chitosan oligosaccharide modifying cotton fiber, and relates to method and technology for modifying a cotton fiber by using chitosan oligosaccharide. The method comprises the following steps: firstly preparing a pretreated cotton fiber by taking the chitosan oligosaccharide and the cotton fiber as raw materials; then reacting epoxy chloropropane and the chitosan oligosaccharide to prepare hydroxypropyl chitosan oligosaccharide; then respectively carrying out etherifying modification on the pretreated cotton fiber by using the hydroxypropyl chitosan oligosaccharide and bis-glycidyl ether successively to prepare an etherate grafted with a hydroxypropyl chitosan oligosaccharide cotton fiber; and finally preparing a chitosan oligosaccharide modifying cotton fiber product through baking treatment. The preparation process disclosed by the invention has the characteristics of moderation in reaction condition, high specificity, simplicity for operation, low cost, convenience for popularization and application and the like. The product prepared by adopting the method has the advantages of antibacterial property and permanent dyeing property and can be widely applied to the fields of spinning, medicines, foods and the like.

The invention relates to a polysaccharide artificial blood vessel and a preparation method and application thereof. The polysaccharide artificial blood vessel is characterized in that the compact artificial blood vessel is prepared from water-insoluble polysaccharide fibers and colloidal solution which are prepared from polysaccharide; the polysaccharide is one or two of carboxymethylcellulose, hydroxy propyl cellulose, hydroxyethylcellulose, hyaluronic acid, alginate, heparin, chondroitin sulfuric acid, chitin, carboxymethyl chitin, hydroxypropyl chitin, hydroxyethyl chitin, carboxymethyl hydroxypropyl chitin, carboxymethyl hydroxyethyl chitin, hydroxypropyl hydroxyethyl chitin, sulfonated chitin, chitosan, carboxymethyl chitosan, hydroxypropyl chitosan, hydroxyethyl chitosan, carboxymethyl hydroxyethyl chitosan, carboxymethyl hydroxypropyl chitosan, hydroxypropyl hydroxyethyl chitosan, sulfonated chitosan or succinyl chitosan. The polysaccharide artificial blood vessel has the high compactness, stretchability, bendability, mechanical strength and flexibility, can be implanted into bodies during the operation of trauma repair, and is used as artificial blood vessels to replace hurt vessels and improve blood-supply condition.

The invention provides special slow release composite fertilizer for red jujubes. The special slow release composite fertilizer consists of the following raw material components in parts by weight: 40-50 parts of edible mushroom slag, 20-30 parts of saw dust, 20-30 parts of rice husks, 8-10 parts of bone powder, 50-60 parts of pig manure, 20-25 parts of vermiculite powder, 5-10 parts of sodium lignosulphonate, 18-20 parts of monoammonium phosphate, 20-30 parts of superphosphate, 10-15 parts of potassium chloride, 20-25 parts of urea, 1-2 parts of zinc sulfate, 1-2 parts of potassium borate, 2-3 parts of ferric sulfate, 0.2-0.4 part of manganese sulfate, 0.5-1.0 part of trichloroisocyanuric acid, 5-8 parts of PPGGE, 5-8 parts of crylic acid, 10-15 parts of polypropylene glycol, 0.1-0.4 part of ammonium persulphate, 4-6 parts of hydroxypropyl chitosan and 10-15 parts of a fertilizer additive. According to the special slow release composite fertilizer for the red jujubes, by the combination of organic and inorganic matters, the soil fertility is improved; by virtue of the added vermiculite powder, heavy metal ions in soil can be effectively absorbed, the yield is increased, and the red jujube quality is improved.

The invention discloses a hydroxypropyl /carbon nanotube decoration electrochemical sensor which mainly comprises a glassy carbon electrode, and the surface of the glassy carbon electrode is coated with a response film; the preparation method of the response film is as follows: a carbon nanotube and hydroxypropyl are added into acetic acid solution, and then homogeneous and light black hydroxypropyl/ carbon nanotube compound dispersion liquid is prepared through an ultrasonic dispersion method; and the dispersion liquid is coated on the glassy carbon electrode, evaporated at room temperature to prepare the response film. The invention also discloses a preparation method of an electrochemical sensor and application of the electrochemical sensor in detecting zinc ions. The electrochemical sensor of the invention has simple and easy manufacturing method and low cost, and has high sensitivity in determining the zinc ions.

The invention relates to the field of daily use chemicals and in particular relates to a facial cleanser for effectively preventing haze hazards. The facial cleanser comprises the following raw materials in parts by weight: 0.1-10 parts of chitosan and derivatives thereof, 5-25 parts of an amino acid-based surfactant and 0.2-3 parts of a thickening agent, wherein the chitosan and derivatives thereof are selected from one or more in chitosan, water-soluble chitosan, N-trimethyl chitosan, N-malely chitosan, carboxymethyl chitosan, hydroxypropyl chitosan or beta-cyclodextrin grafted chitosan; and the deacetylation degree of the chitosan and derivatives thereof is 60-99 percent. The chitosan and derivatives thereof are added into the amino acid-based facial cleanser, and the slightly acidic facial cleanser disclosed by the invention is rich in foam, high in stability, mild and non-irritating, has the effects of inhibiting bacteria and chelating heavy metals and is applied to skin care in hazy weather.

The invention discloses a medical chitosan dressing, and a preparation method thereof. The medical chitosan dressing is characterized in comprising following raw materials, by weight, 25 to 40 parts of chitosan, 15 to 25 parts of hydroxypropyl chitosan, 5 to 15 parts of sodium hyaluronate, 1 to 5 parts of an antibacterial agent, 2 to 8 parts of a calming anti-inflammatory agent, and 2 to 10 parts of a plasticizer. The medical chitosan dressing is suitable for medical hemostasis, antibiosis and antiphlogosis, and promoting of wound healing.

The invention discloses a plant energy concentration fertilizer, which is characterized in that the fertilizer is formed by the following raw materials in parts by weight: 250-650 parts of compound amino acid concentrated solution, 100-120 parts of trace element, 0-100 parts of magnesium sulfate, 0-30 parts of agricultural rare earth, 0-300 parts of dicyandiamide, 2-10 parts of water-retaining agent, 100-300 parts of oligosaccharins or polysaccharide and 10-20 parts of hydroxypropyl chitosan. The preparation method is that compound amino acid concentrated solution and trace element are added into a reaction kettle according to the weight parts for chelation reaction when heating and agitation are conducted; and after the chelation reaction is over, the reaction solution is cooled to normal temperature, and then magnesium sulfate, agricultural rare earth, dicyandiamide, water-retaining agent, oligosaccharins or polysaccharide and hydroxypropyl chitosan are added into the reaction solution according to the weight parts, are agitated for 20-26 hours and are packaged to obtain the product. The plant energy concentration fertilizer prepared through the method has the advantages that the dosage is less, the utilization ratio is high, the foliage spray adhesive force is strong, the fertilizer contains no hormone, no toxicity, no harmfulness, no pollution and no residue are caused, and the growth of plants is effectively promoted.

The present invention discloses a preparation method and application of a printing electrode electrochemical immunosensor for simultaneous detection of multiple aflatoxins, and belongs to technical fields of biological sensing, nano-functional materials and food safety analysis. The surface of a rectangular substrate coated with a polyester film is printed with seven electrodes, including five carbon working electrodes, a silver reference electrode and a counter electrode, and with seven electrode lead lines and electrode lead line ends. The present invention is characterized in that: a silver nanoparticles-nitrogen-doped graphene-hydroxypropyl chitosan conductive composite nanomaterial is used for fixing aflatoxin B1, aflatoxin B2, aflatoxin G1, aflatoxin G2, and total aflatoxin antibody to the surfaces of each working electrode, a detection liquid is dripped and coated on the working electrodes and the working electrodes are connected with a detection circuit of a multi-channel electrochemical workstation, thus the simultaneous detection of five aflatoxins are achieved. The sensor is simple in preparation, easy for processing, low in cost, and easy to carry. The detection method is simple, rapid, high in sensitivity and good in specificity.

The invention discloses biocompatible polyurethane modified by sulfonated hydroxypropyl chitosan and a method for preparing the biocompatible polyurethane. The method includes synthesizing the sulfonated hydroxypropyl chitosan from chitosan by means of etherification reaction and sulfonation treatment, then adding diphenyl-methane-diisocyanate, polyethylene glycol and catalysts into a reactor and carrying out stirring reaction under the protection of nitrogen at the temperatures of 70-80 DEG C for 2-4 h; adding the sulfonated hydroxypropyl chitosan into reaction products and carrying out cooling reaction for 6-12 h to obtain the biocompatible polyurethane modified by the sulfonated hydroxypropyl chitosan. The biocompatible polyurethane and the method have the outstanding advantages that the sulfonated hydroxypropyl chitosan which is a water-soluble heparinoid substance is covalently grafted on polyurethane long chains, and accordingly the hydrophilicity and the anticoagulation properties of polyurethane can be greatly improved; processes are simple, reaction conditions are mild and are easy to control, and raw materials are easily available and are low in cost.

Provided are O-hydroxypropyl chitosan and a preparation method thereof, wherein the preparation method comprises the steps: adding chitosan to a sodium hydroxide solution, alkalizing, then adding intoisopropanol, stirring evenly, heating up to 40-80 DEG C, then adding a tetramethylammonium hydroxide solution and epoxypropane, continuing to carry out reaction for 3-8 h, allowing to stand, pouringto remove an upper-layer supernatant, adjusting the pH value to 6.5-7.5, then adding a mixed solution of acetone and ethanol, carrying out suction filtration to obtain a filter cake, carrying out Soxhlet extraction, and drying to obtain O-hydroxypropyl chitosan. O-hydroxypropyl chitosan is prepared by a nucleophilic substitution reaction of chitosan and epoxypropane. -OH of a C6 site of chitosan is activated by alkalization of sodium hydroxide, the modification position is clear, the purity is high, the post treatment is simple, and the product has good flocculation performance.

The invention belongs to the technical field of biomedical materials and specifically relates to a method for preparing a hydrogel film for curing chemotherapeutic phlebitis. The method includes introducing an azide group (4-azidobenzoic acid) with optical reaction activity onto an amino group of water-soluble hydroxypropyl chitosan to prepare light cross-linked azide hydroxypropyl chitosan, and subjecting an azide hydroxypropyl chitosan aqueous solution to irradiation and crosslinking by an ultraviolet lamp to obtain the chitosan hydrogel film with bioadhesion. According to the chitosan hydrogel film, general characteristics of blood stopping, pain relieving, bacterium inhibiting, anti-inflammation and antioxidation of chitosan are achieved, advantages of good biocompatibility, good moisture retention, good water vapor permeability and high adhesion strength of hydrogel materials are achieved, and the chitosan hydrogel film is convenient to use, good in comfort degrees and good in effect of preventing and curing the chemotherapeutic phlebitis.

The invention relates to a sensor and an application thereof, and concretely relates to a hydroxypropyl chitosan/carbon nanotube modified electrochemical sensor and an application thereof. The electrochemical sensor which is obtained by treating a glassy carbon electrode as a working electrode and coating the surface of the glassy carbon electrode with a hydroxypropyl chitosan/carbon nanotube response film can be used to detect the content of Pb ions in wastewater. The working electrode of the electrochemical sensor of the present invention has the advantages of simple and easily implemented manufacturing method, low cost, and high sensitivity when the working electrode is used to detect the Pb ions.

The invention relates to a chitosan carbon steel restrainer, which comprises components that are more than one selected from hydroxypropyl chitosan and carboxymethyl chitosan. The use of chitosan carbon steel restrainer is that the restrainer can be added into cleaning solution to clean steel by immersion. The cleaning solution is acid liquor, the addition amount of the restrainer in the acid liquor is 0.001 to 3.0 g/L, and the immersion is performed at room temperature for 0.5 to 4 hours. The product of the invention is used for surface cleaning of carbon steel and carbon steel product and the method can prevent over metal etching and excessive acid liquor consumption during cleaning and has the outstanding advantages of low price, low dosage, high efficiency and high continuous acting force.

The invention belongs to the field of metal corrosion and protection and particularly relates to a chitosan modified derivative corrosion inhibitor and a preparation method thereof. Application of the modified derivative to other fields such as the biological field and the medicine field is not subjected to related verification or illustration. The chitosan modified derivative corrosion inhibitor is carboxymethylation hydroxypropyl chitosan, that is, chitosan is modified through carboxymethylation and hydroxypropylation, a carboxymethyl group and a hydroxypropyl group are introduced, and the chitosan derivative with multiple substituent groups is obtained. The environment-friendly chitosan modified derivative corrosion inhibitor and the preparation method thereof are applicable to a corrosive medium, the production process is simple, the raw material source is wide, and the chitosan modified derivative has good water solubility and biocompatibility.

The invention discloses a polysaccharide hemostatic dressing as well as a preparation method and an application thereof. The polysaccharide hemostatic dressing is membrane or sponge-like product prepared by carrying out a cross-linking reaction on aminopolysaccharides and oxidized polysaccharides, wherein the aminopolysaccharides refer to one or more of hyaluronic acid, chondroitin sulfate, heparin, chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, sulfonated chitosan, hydroxybutyl chitosan, carboxymethyl chitosan, succinyl chitosan or other chitosan derivatives; the oxidized polysaccharides refer to one or more of oxidized polysaccharides containing dialdehyde groups; and saccharide units containing the dialdehyde groups account for 1-70% of total saccharide units of the polysaccharide molecule. The polysaccharide hemostatic dressing disclosed by the invention has an obvious hemostasis effect, is capable of obviously shortening the hemostasis time of the wound surface, is non-toxic, and has excellent biocompatibility. The polysaccharide hemostatic dressing can be used for preparing medical apparatuses and instruments for traumatic hemostasis and surgical hemostasis, servesas hemostatic dressing medical apparatuses and instruments to be developed, and has wide market prospects.

The present invention is directed to a nail lacquer consisting essentially of terbinafine as an antimycotic agent, hydroxypropyl chitosan as film forming agent, water and a lower alkanol as solvents. The invention is also directed to a method for treating onychomycosis by topically administering such a nail lacquer to a patient in need of such a treatment.

The invention discloses dehydroabietyl glycidyl ether grafted water-soluble hydroxypropyl chitosan and a preparation method thereof. The compound is a compound with a structure as shown in general formula (I), the preparation method comprises two main processes, namely preparation of water-soluble hydroxypropyl chitosan and preparation of dehydroabietic glycidyl ether grafted water-soluble hydroxypropyl chitosan; the non-ionic surfactant dehydroabietyl glycidyl ether grafted water-soluble hydroxypropyl chitosanbased on natural renewable rosin and chitosan as raw materials is obtained. The preparation method comprises the following steps: alkalizing chitosan, and reacting the alkalized chitosan with epoxypropane to generate hydroxypropyl chitosan; hydrolyzing the generated hydroxypropyl chitosan under the assistance of ultrasonic waves to obtain the water-soluble hydroxypropyl chitosan of which the water solubility is remarkably improved and the molecular weight is reduced; reacting thewater-soluble hydroxypropyl chitosan with dehydroabietyl glycidyl ether; finally, generating the novel nonionic surfactant dehydroabietic glycidyl ether grafted water-soluble hydroxypropyl chitosan with the average grafting degree of (2-hydroxy-3-dehydroabietic oxy) propyl on a glucosamine unit reaching 5 to 100% and the average grafting degree of hydroxypropyl reaching 50 to 300%.

The invention discloses an acid dye leveling agent. The acid dye leveling agent contains the ingredients in percentage by mass: 5-20% of N-fat acylated-O-hydroxypropyl chitosan, 10-25% of N-fat acylated chitosan oligosaccharide, 5-15% of nonionic surfactant cardanol polyoxyethylene ether and the balance of water. According to the acid dye leveling agent, a compounding technology is adopted, so that the leveling effect of the product is optimized, the application effect reaches the effect of the conventional leveling agents prepared from petroleum-based surfactants, and the acid dye leveling agent can replace petroleum-based products.

The invention relates to a composite adsorption material for treatment of industrial waste water and a preparation method thereof. The composite adsorption material is characterized by comprising 5 to 15 parts of polyaluminum silicate sulfate, 3 to 10 parts of polyaluminum chloride, 4 to 8 parts of macroporous adsorption resin D1300, 4 to 9 parts of macroporous adsorption resin H103, 3 to 8 parts of polyethelene alcohol fiber, 2 to 5 parts of Arabic gum, 4 to 9 parts of hydroxypropyl chitosan, 3 to 7 parts of barium sulfate and 4 to 7 parts of lithium carbonate. The preparation method comprises the following steps: step 1, crushing barium carbonate and lithium carbonate with a crusher until the particle size of both barium carbonate and lithium carbonate is 150 to 300 meshes; and step 2, respectively weighing the above-mentioned components according to weight parts and uniformly mixing the components to prepare the composite adsorption material for treatment of industrial waste water.