100 results about "Hydroxycinnamic acid" patented technology

The invention belongs to the technical field of microorganisms, and discloses a Lactobacillus paracasei B20 for inhibiting melanin from a plateau area and application of the Lactobacillus paracasei B20, the Lactobacillus paracasei B20 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.32434, and the preservation date is October 31, 2024. Metabolite of the lactobacillus paracasei B20 comprises phenylalanine, p-hydroxycinnamic acid and the like, has strong tyrosinase inhibition effect and anti-ultraviolet ability, and can significantly reduce generation of melanin in skin. In addition, the lactobacillus paracasei B20 also has relatively strong oxidation resistance, has good tolerance in artificial gastric juice and artificial intestinal juice, and can smoothly reach the intestinal tract of a human body. In addition, the lactobacillus paracasei B20 has a relatively obvious growth inhibition effect on skin conditioned pathogens such as staphylococcus aureus and enterococcus faecalis.

The invention discloses a preparation method of ethyl 4-chloroacetoacetate, and belongs to the technical field of compound synthesis. The method comprises the following steps: by taking diketene as a raw material, adding a polymethylsilsesquioxane polymerization inhibitor into a dichloromethane solvent, introducing chlorine at low temperature, carrying out chlorination reaction to generate 4-chloroacetoacetic acid, then esterifying the 4-chloroacetoacetic acid with absolute ethyl alcohol to obtain a crude product, and finally distilling and purifying to obtain the product. The preparation method is characterized in that a polymethylsilsesquioxane polymerization inhibitor is added before chlorination reaction, the polymerization inhibitor is prepared by grafting a functional monomer containing a 3, 5-di-tert-butyl-4-hydroxycinnamic acid structure onto surface-ethenylated polymethylsilsesquioxane microspheres, and the polymethylsilsesquioxane polymerization inhibitor has both steric hindrance and free radical capture capability. The method can effectively inhibit the self-polymerization and copolymerization tendency of diketene, intermediates and products in a reaction system, obviously reduces the generation of by-products such as dichloro and polychloro, enables the product to be high in yield and good in purity, and meets the quality requirements of high-end medical intermediates.

The invention discloses a sugar derivative of hydroxycinnamic acid as well as a preparation method and application thereof in cosmetics. Specifically, the invention provides a sugar derivative of hydroxycinnamic acid. The compound is shown as a formula I in the specification. Compared with original hydroxycinnamic acid, the sugar derivative of hydroxycinnamic acid has better water solubility and stability, and has one or more effects of oxidation resistance, whitening, soothing, moisturizing, ultraviolet absorption and the like; when the composition is applied to cosmetics, light aging damage of skin can be relieved, and skin color can be brightened; .

The application discloses application of 2-amino isophthalic acid (2-AIA) as a MALDI matrix in characterization of oligosaccharide additives in food. The skeleton structure of 2-AIA has a strong ultraviolet absorption group and a protonation site, which is beneficial to laser energy transmission and desorption ionization process of the measured object. Meanwhile, 2-AIA has multiple polar functional groups, which can effectively enhance the directional combination of the hydroxyl group of 2-AIA and oligosaccharide, and improve the anti-interference ability of impurities in a complex system. In addition, 2-AIA and a traditional organic matrix alpha-cyano-4-hydroxycinnamic acid (CHCA) are combined as a binary matrix (CHCA / 2-AIA), which can play a synergistic role of the double matrix, significantly improve the detection sensitivity of oligosaccharide. On the other hand, the combination of CHCA and 2-AIA with different pH values can significantly improve the uniformity of the co-crystallization, and improve the accuracy and reproducibility of quantitative detection.

The invention discloses a corrosion-resistant polypropylene insulated cable and a preparation process thereof, and belongs to the technical field of cables. The corrosion-resistant polypropylene insulated cable sequentially comprises a cable core, a wrapping layer, an inner sheath layer, an armor layer and an outer sheath layer from inside to outside, the inner sheath layer and the outer sheath layer are both made of a corrosion-resistant polypropylene cable material; the corrosion-resistant polypropylene cable material is prepared from the following raw material components: polypropylene, POE (Polyolefin Elastomer), a plasticizer, a composite flame retardant, a heat-conducting filler, a lubricant, an ultraviolet light absorber and a nucleating agent, the composite flame retardant is prepared from the following raw materials: cyanuric chloride, 4-hydroxymethyl-1-oxo-1-phospha-2, 6, 7-trioxabicyclo [2.2. 2] octane, hydroxyl N-alkoxy hindered amine, ethidene diamine and N-(2-aminoethyl) maleimide; the heat-conducting filler is prepared from the following raw materials: graphene oxide, a silane coupling agent, boron nitride and 3, 5-di-tert-butyl-4-hydroxycinnamic acid; the corrosion-resistant polypropylene insulated cable prepared by the invention is relatively good in corrosion resistance, heat dissipation performance, flame retardance, thermo-oxidative aging resistance and mechanical property.

The present invention provides a method for simultaneously determining multiple index components in Wendan Tablets. In this method, Wendan Tablets are used as test samples for high-performance liquid chromatography detection to simultaneously determine p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid in Wendan Tablets. The method of the present invention can also quantitatively determine the contents of the above four components in Wendan Tablets, and the quantitative determination methods include the external standard method and the multiple components by single marker method. The determination method of the present invention realizes the qualitative and quantitative determination of multiple components (p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid) in Wendan Tablets. Among them, the multiple components by single marker quantitative detection method not only ensures the quality, stability, and controllability of the preparation, but also reduces the detection cost of purchasing reference substances, achieving excellent technical effects and having broad application prospects.

To provide a rubber composition to be a raw material of a vulcanized rubber excellent in steering stability and wet grip performance when used as a rubber part of a pneumatic tire, especially a pneumatic tire for motor sports.SOLUTION: A rubber composition comprising 100 parts by mass of a rubber ingredient containing at least a diene rubber, 0.1 to 10 parts by mass of a cinnamic acid compound having a hydroxyl or methoxy group-substituted aromatic ring, and 40 to 140 parts by mass of carbon black having a nitrogen-adsorption specific surface area of 140 to 250m2 / g. The cinnamic acid compound is a naturally occurring compound and is preferably at least one of 3, 4-dihydroxycinnamic acid and 3, 4-dimethoxycinnamic acid.SELECTED DRAWING: None

The invention relates to the technical field of biological medicine, in particular to application of esterified derivatives of methyl p-hydroxycinnamate in preparation of antitumor drugs. Experiments show that the derivative has an obvious inhibition effect on the cell viability of tumor cells such as gastric cancer, nasopharynx cancer and breast cancer, particularly has obvious proliferation, migration and invasion inhibition ability on the gastric cancer cells, can induce apoptosis of the gastric cancer cells, has relatively low toxic and side effects, and provides a new medicine for treating the gastric cancer.

The present invention relates to a composition comprising: 1) at least one inorganic UV filter selected from titanium dioxide; 2) at least one α-cyanodiphenylacrylate derivative of the given formula; and 3) at least one 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative of the given formula. The present invention also relates to a cosmetic method for treating skin against UV radiation using said composition.

The invention provides a supramolecular assembly which comprises at least one hydroxycinnamic acid derivative and at least one betaine compound, and the betaine compound and the hydroxycinnamic acid derivative are assembled through non-covalent bond acting force. The invention also provides a cosmetic composition containing the supramolecular assembly and a method for preparing the supramolecular assembly.

The present invention provides a biomass-derived polyester compound useful as a rubber material or an adhesive material, the compound including a multiple bond in the molecule. By synthesizing an ester compound composed of a hydroxycinnamic acid and a fatty acid, and carrying out polycondensation reaction using the ester compound as a monomer, a polyester compound containing cinnamic acid and a ricinoleic acid derivative that are alternately linked to each other can be efficiently obtained. For example, an ester compound of General Formula (1) is produced. (In the formula, the substituents R1 and R2 each represent a hydrogen atom or a methoxy group; the substituent R3 represents an alkyl group or an alkenyl group; and n represents an integer of 10 to 100).

The present invention discloses a method for enzymatic hydrolysis extraction of a wild ginseng-like product, belonging to the technical field of wild ginseng. Some rare saponins in wild ginseng can promote cell growth and division and improve the body. Through specific active enzymes, the prototype saponins can be enzymatically hydrolyzed to generate different rare saponins. In the present invention, through the action of radio frequency plasma, a mixed gas of α-linolenic acid vapor and nitrogen is used to treat the ultrafiltration membrane, thereby introducing double bond groups onto the ultrafiltration membrane; an esterification reaction occurs between p-hydroxycinnamic acid and cellulase to generate a product with reactive activity; these products undergo graft polymerization with the double bonds on the surface of the ultrafiltration membrane to form a more stable and more functional modified ultrafiltration membrane; the present invention can effectively separate and extract the target substances through a combination of enzymatic hydrolysis and ultrafiltration membrane fractionation; the molecular weight distribution of the peptides released during the enzymatic hydrolysis process is within a certain range, which helps to precisely separate these substances through the ultrafiltration membrane, and the extraction rate is high.

The present application provides a kind of compound composition for preventing and treating plant wilt, the composition composition includes 4-hydroxy cinnamic acid and thymol, mass ratio is 1:1~1:2;The mass ratio of the composition is 1:1, the concentration of the composition is 60~300 μg / mL;The mass ratio of the composition is 1:2, the concentration of the composition is 50~200 μg / mL;The present application can inhibit the growth of pepper fusarium oxysporum f.sp.cubense mycelium, spore germination and sporulation, and can play a synergistic effect.The composition in the present application can significantly reduce the incidence of wilt in pot experiment.Compared with the prior art, the present application aims to reduce the use of chemical pesticides by low-cost, safe and efficient plant-derived antibacterial compounds.

Disclosed herein are recombinant host cells and methods capable of producing tyramine-containing hydroxycinnamic amide compounds, derivatives, and extracts.SOLUTION: Some embodiments provided include, for example, consumable products containing tyramine-containing hydroxycinnamic acid amides produced by recombinant host cells. Some embodiments provided herein are methods for producing tyramine-containing hydroxycinnamic amide or hydroxycinnamic amide derivatives.SELECTED DRAWING: None

A cosmetic skin care composition having a peptide derivative, a fatty acid having from about 8 to about 22 carbon atoms, and a dermatologically acceptable carrier. The peptide derivative has a formula: Rc-R1-Gly-Pro-Gln-Gly-R2, where Rc is chosen from hydroxycinnamic acid, its derivative, and mixtures thereof, where R1 and R2 are respectively from about 0 to about 8 amino acids, and wherein a total of R1 and R2 is 8 or less amino acids; The composition provides improved penetration of such peptide derivatives to skin.

A matrix solution used to be mixed with a sample in a matrix-assisted laser desorption / ionization mass spectrometry method. The matrix solution is an aqueous solution containing acetonitrile, ethanol, trifluoroacetic acid, and water. A content of the acetonitrile is 30 to 40 vol% based on the matrix solution. A content of the ethanol is 10 to 20 vol% based on the matrix solution. A content of the trifluoroacetic acid is 1 to 3 vol% based on the matrix solution. The matrix solution contains α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, or sinapinic acid in a ratio of 5 to 20 mg / ml.

This invention generally relates to the use of hydroxycinnamic acid or its derivatives, such as alginate, in cosmetic or therapeutic settings. The invention further relates to compositions comprising hydroxycinnamic acid or its derivatives.

The present invention relates to the use of specific hydroxycinnamic acid salts for stabilizing organic materials. The invention also relates to the corresponding organic materials stabilized by incorporation of specific hydroxycinnamic acid salts and to methods for stabilizing organic materials. Furthermore, aluminum salts of specific hydroxycinnamic acids are described which are suitable as organic stabilizers. The invention also relates to stabilizer compositions comprising the corresponding hydroxycinnamic acid salts.

The present invention relates to a method for obtaining an extract of the leaves of Rosmarinus officinalis (rosemary) involving two stages of maceration, filtration, concentration of the two drained products and drying, guaranteeing an extract comprising mainly hydroxycinnamic derivatives, rosmarinic acid, luteolin, neptin and carnosol, and the use of the extract in cosmetic compositions in the prevention and treatment of androgenetic alopecia, in which the extract of the invention acts through multiple mechanisms of action, and can be used in men and women.

The invention discloses a modified polyester film for an automobile window and a preparation method of the modified polyester film, and relates to the technical field of polyester films. When the modified polyester film for the automobile window is prepared, firstly, methyl p-hydroxycinnamate reacts with [chlorine (ethyoxyl) phosphonyl] benzene to prepare a modified phosphorus-containing cinnamic acid diester compound; the preparation method comprises the following steps: reacting nano antimony tin oxide with a silane coupling agent to prepare pre-modified nano antimony tin oxide; the pre-modified nano tin antimony oxide is subjected to a reaction with thiazolidine acid, 6-maleimido-1-hexanal and ethyl isocyano acetate, and modified nano tin antimony oxide is prepared; carrying out copolycondensation on terephthalic acid, ethylene glycol, the modified phosphorus-containing cinnamic acid diester compound, 2, 2 '-difuran-5, 5'-dicarboxylic acid dimethyl ester and the modified nano tin antimony oxide to obtain modified polyester; and carrying out hot-pressing film formation on the modified polyester to obtain the modified polyester film for the automobile window. The prepared modified polyester film for the automobile window has the advantages of flame retardance, ultraviolet shielding, heat insulation, self-repairing and aging resistance.

The present invention discloses an edible treatment composition comprising non-toxic and non-hazardous chemicals to extend the shelf-life and maintain freshness of mushroom for prolonged time during its storage and shipment. The disclosed edible treatment composition includes Kojic Acid, L-arginine, Hydroxycinnamic acid (HCA) and optionally additional active or inactive components like antimicrobial agent, etc. This invention is concerned with the treatment of mushroom with disclosed edible treatment composition, pre- or post-harvest, to extend its shelf-life by imparting one or more properties like, maintained whiteness, delayed browning, delated pileus (cap) opening, better firmness, maintained structural integrity, slower weight-loss, etc. for prolonged time, amongst others.

A low-pH, aqueous skin care composition, comprising: a) 0.1 to 10% of a hydroxycinnamic acid (HCA); and b) 0.1% to 5% of a hydrotrope selected from the group consisting of: phenolic acid, derivatives of phenolic acid, phenolic alcohol, derivatives of phenolic alcohol, and mixtures thereof; wherein the hydrotrope has a pKA less than the formula pH; and wherein the hydrotrope has the partition coefficient (log P) of less than 3.0; c) water, and wherein the pH of the composition is less than 5.0.

The invention provides application of dragon's blood and active ingredients thereof in preparation of a medicine for treating heart failure, and belongs to the technical field of biological medicine. It is found for the first time that the dragon's blood can significantly improve the heart function of a heart failure model animal, reduce the level of a heart failure marker and relieve cardiac hypertrophy, cardiac pulmonary edema, myocarditis infiltration and fibrosis; core active components such as genistein and 3-hydroxycinnamic acid are screened and verified, wherein the genistein can reproduce the overall treatment effect of the dragon's blood. The invention also discloses that the core action mechanism of the composition is to promote macrophage VEGFC secretion, increase heart lymphatic vessel density and promote lymphatic vessel neogenesis, and a brand new natural drug candidate scheme and an intervention strategy are provided for heart failure treatment.

This invention discloses a modified polyester film for automotive windows and its preparation method, relating to the field of polyester film technology. In preparing the modified polyester film for automotive windows, the invention first reacts methyl p-hydroxycinnamate with [chloro(ethoxy)phosphono]benzene to obtain a modified phosphorus-containing cinnamate diester compound; then reacts nano-antimony tin oxide with a silane coupling agent to obtain pre-modified nano-antimony tin oxide; the pre-modified nano-antimony tin oxide is then reacted with thiazopyridine acid, 6-maleimide-1-hexanal, and ethyl isocyanate to obtain modified nano-antimony tin oxide; terephthalic acid, ethylene glycol, the modified phosphorus-containing cinnamate diester compound, dimethyl 2,2'-difuran-5,5'-dicarboxylic acid, and the modified nano-antimony tin oxide are co-condensed to obtain a modified polyester; the modified polyester is then hot-pressed into a film to obtain the modified polyester film for automotive windows. The modified polyester film for automotive windows prepared by this invention has the advantages of flame retardancy, UV shielding, heat insulation, self-healing, and anti-aging properties.

The invention discloses a sunscreen synergistic supramolecule as well as a preparation method and application thereof, and belongs to the technical field of supramolecules. The sunscreen synergistic supramolecule comprises a sunscreen synergistic substance and a ligand, and the sunscreen synergistic substance is connected with the ligand through an intermolecular acting force; the sunscreen synergistic substance is a ferulic acid substance, a 4-hydroxycinnamic acid substance, a baicalin substance, a chlorogenic acid substance or a rutin substance; the ligand is tranexamic acid, nicotinamide, arbutin, tartaric acid or ascorbic acid. The sunscreen synergistic supramolecule provided by the invention has relatively good biocompatibility and mildness, after the sunscreen synergistic supramolecule is added, the stability and the sunscreen effect of the sunscreen agent are remarkably improved, and the biological activity and the effect of the sunscreen agent are improved.

The invention discloses application of 2-hydroxycinnamic acid in treatment of gastric cancer, according to the application, the influence of supernate of lactobacillus salivarius or lactobacillus crispatus on gastric cancer cell apoptosis is detected through a flow technology, and the 2-hydroxycinnamic acid is found to be capable of promoting the gastric cancer cell apoptosis and inhibiting the activity of gastric cancer organs. A metabolite in a supernatant of lactobacillus salivarius CICC23175 or lactobacillus crispatus CGMCC1.2743 screened by non-target metabolite omics contains 2-hydroxycinnamic acid, and the gastric cancer cytotoxic resistance of 2-hydroxycinnamic acid is deeply studied to find that the 2-hydroxycinnamic acid not only has the effects of inhibiting gastric cancer cell proliferation, colony formation and cell migration, but also has the effects of inhibiting gastric cancer cell proliferation, colony formation and cell migration. In addition, the 2-hydroxycinnamic acid can also increase the proportion of cells in a G1 / G0 period of a cell cycle, promote apoptosis of gastric cancer cells, and find that the inhibition effect of the 2-hydroxycinnamic acid on proliferation of gastric cancer organs is integrally higher than that of normal gastric epithelium organs.

The invention relates to an establishment method of a high performance liquid characteristic chromatogram of a phlegm reducing preparation and a component content determination method, and belongs to the field of medicine analys.The establishment method of the high performance liquid characteristic chromatogram of the phlegm reducing preparation comprises the following steps that S1, a reference substance solution is prepared; s2, preparing a test solution; s3, determining chromatographic conditions; s4, collecting chromatograms of the reference substance solution and multiple batches of test substance solutions, analyzing the chromatograms of the test substance solutions, calibrating 13 common peaks, and identifying characteristic peaks of 6 components; s5, p-hydroxycinnamic acid and praeruptorin A are taken as double-standard reference substances, other 11 characteristic peaks are effectively predicted and positioned through two reference substances by adopting a double-standard linear correction method, the method is good in scientific accuracy and durability and economical, and the method is beneficial to comprehensively and effectively controlling the quality of the phlegm reducing preparation.

The present invention provides a recombinant bacterium and a method for producing p-hydroxycinnamic acid using the recombinant bacterium. Heterologous aldolase and fumarase genes are integrated into the genome of the recombinant bacterium.

The present invention belongs to the technical field of binders, and particularly relates to a high-iron and low-silicon composite binder for iron ore pellets and a preparation method thereof. On the basis of the existing technology, the present invention uses citric acid-crosslinked starch and cyclodextrin to obtain modified starch. After preparing magnesium iron hydrotalcite, it is calcined and oxidized and then intercalated with p-hydroxycinnamic acid to obtain modified magnesium iron hydrotalcite. The cavity structure of cyclodextrin and the carboxyl functional group of citric acid in the modified starch can undergo a complexation reaction with metal ions on the surface of iron ore powder, enhancing the bonding strength of the pellets; the intercalation of p-hydroxycinnamic acid into magnesium iron hydrotalcite improves the thermal stability and dispersion performance of magnesium iron hydrotalcite. The high-iron and low-silicon composite binder for iron ore pellets obtained by compounding modified starch, modified magnesium iron hydrotalcite, bentonite, sodium carboxymethylcellulose and a dispersant has excellent bonding performance, reduces the addition amount of bentonite and increases the iron content of iron ore pellets, and improves the green pellet strength and thermal stability of iron ore pellets.

The invention provides an application of an HXT4 gene or an HXT4 protein in improving the tolerance of saccharomyces cerevisiae to a hydroxycinnamic acid compound. The recombinant plasmid containing the HXT4 gene is transferred into the saccharomyces cerevisiae, so that the tolerance concentration of the saccharomyces cerevisiae to hydroxycinnamic acid compounds such as coumaric acid and ferulic acid can be increased from 1 mg / mL to 10 mg / mL, that is, overexpression of the HXT4 gene in the saccharomyces cerevisiae can significantly improve the tolerance of the saccharomyces cerevisiae to the hydroxycinnamic acid compounds; the purpose of adding more hydroxyl cinnamic acid compounds into products (such as medicines, health-care products, cosmetics or foods) containing the saccharomyces cerevisiae is achieved, and the quality of the products is further remarkably improved.