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128 results about "Hydroxycinnamic acid" patented technology

Hydroxycinnamic acids (hydroxycinnamates) are a class of aromatic acids or phenylpropanoids having a C₆–C₃ skeleton. These compounds are hydroxy derivatives of cinnamic acid.

Lactobacillus paracasei B20 derived from plateau region and capable of inhibiting melanin and application of lactobacillus paracasei B20

The invention belongs to the technical field of microorganisms, and discloses a Lactobacillus paracasei B20 for inhibiting melanin from a plateau area and application of the Lactobacillus paracasei B20, the Lactobacillus paracasei B20 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.32434, and the preservation date is October 31, 2024. Metabolite of the lactobacillus paracasei B20 comprises phenylalanine, p-hydroxycinnamic acid and the like, has strong tyrosinase inhibition effect and anti-ultraviolet ability, and can significantly reduce generation of melanin in skin. In addition, the lactobacillus paracasei B20 also has relatively strong oxidation resistance, has good tolerance in artificial gastric juice and artificial intestinal juice, and can smoothly reach the intestinal tract of a human body. In addition, the lactobacillus paracasei B20 has a relatively obvious growth inhibition effect on skin conditioned pathogens such as staphylococcus aureus and enterococcus faecalis.
Owner:XIAMEN YUANZHIDAO BIOTECHNOLOGY CO LTD

Anthocyanin-based colorant

ActiveUS12274278B2Organic active ingredientsFrozen sweetsBenzoic acidTints and shades
1. A composition, which is an anthocyanin-based colorant composition comprising 50-90 mol-%, based on the total amount of anthocyanins, of pelargonidin-based anthocyanins, and wherein (i) >70 mol-% of all anthocyanins are acylated with at least one phenolic acid; and (ii) >20 mol-% of all anthocyanins are acylated with at least one hydroxycinnamic acid; and wherein the composition has a red color with a hue value H≥ in the L*C*h* color system in the range of 10-30, measured at an L*-value of (70.0±0.1) in a 0.1 mol / l trisodium citrate dihydrate buffer at pH 3 in a 1 cm-length quartz cell using Spectraflash 650 (Datacolor) in transmission mode under D65 illuminant 10 Deg. Also, the present invention relates to use of the above compositions as a food colorant.
Owner:OTERRA AS

Acid solution thickening agent and preparation method thereof

The invention relates to the technical field of oil fields, and discloses an acid liquor thickening agent and a preparation method thereof.The preparation method comprises the steps that 3, 4-dihydroxycinnamic acid, acrylamide, sodium alkenyl sulfonate modified boric acid and quaternized cardanol are added into water and mixed to be uniform, citric acid continues to be added to adjust the pH, nitrogen continues to be introduced, azodiisobutyronitrile, potassium persulfate and sodium pyrosulfite are added into the mixture, and the mixture is stirred to be uniform; and after the reaction, filtering and washing to obtain the acid liquor thickening agent. The acid liquor thickening agent contains adamantane and benzene ring rigid groups, so that the rigidity of the acid liquor thickening agent is improved, and the anti-shearing capability and the stability of the acid liquor thickening agent are also enhanced; the quaternary ammonium salt group and the sodium sulfonate group improve the temperature resistance and the shear resistance of the acid liquor thickening agent.
Owner:CHIFENG AOLONG CHEM CO LTD

Compositions and methods for inhibiting blood cancer cell growth

Methods, compositions and uses for inhibiting the growth in blood cancer cells with one or more of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE), CAPE analogue MT30, and CAPE analogue GL8. The blood cancer cells can be myeloma, lymphoma and leukemia cells. The methods, compositions and uses can be in conjunction with the use of an IMiD to treat a patient. The compositions can include a pharmaceutically acceptable carrier, adjuvant or vehicle, a pharmaceutically acceptable salt or dietary supplement.
Owner:UNIVERSITY OF NEW BRUNSWICK +1

Preparation method of ethyl 4-chloroacetoacetate

The invention discloses a preparation method of ethyl 4-chloroacetoacetate, and belongs to the technical field of compound synthesis. The method comprises the following steps: by taking diketene as a raw material, adding a polymethylsilsesquioxane polymerization inhibitor into a dichloromethane solvent, introducing chlorine at low temperature, carrying out chlorination reaction to generate 4-chloroacetoacetic acid, then esterifying the 4-chloroacetoacetic acid with absolute ethyl alcohol to obtain a crude product, and finally distilling and purifying to obtain the product. The preparation method is characterized in that a polymethylsilsesquioxane polymerization inhibitor is added before chlorination reaction, the polymerization inhibitor is prepared by grafting a functional monomer containing a 3, 5-di-tert-butyl-4-hydroxycinnamic acid structure onto surface-ethenylated polymethylsilsesquioxane microspheres, and the polymethylsilsesquioxane polymerization inhibitor has both steric hindrance and free radical capture capability. The method can effectively inhibit the self-polymerization and copolymerization tendency of diketene, intermediates and products in a reaction system, obviously reduces the generation of by-products such as dichloro and polychloro, enables the product to be high in yield and good in purity, and meets the quality requirements of high-end medical intermediates.
Owner:INNER MONGOLIA HUAZHOU PHARM CO LTD

Sugar derivative of hydroxycinnamic acid, preparation method of sugar derivative and application of sugar derivative in cosmetics

The invention discloses a sugar derivative of hydroxycinnamic acid as well as a preparation method and application thereof in cosmetics. Specifically, the invention provides a sugar derivative of hydroxycinnamic acid. The compound is shown as a formula I in the specification. Compared with original hydroxycinnamic acid, the sugar derivative of hydroxycinnamic acid has better water solubility and stability, and has one or more effects of oxidation resistance, whitening, soothing, moisturizing, ultraviolet absorption and the like; when the composition is applied to cosmetics, light aging damage of skin can be relieved, and skin color can be brightened; .
Owner:SHANGHAI ZHONGYI DAILY CHEM CO LTD

2-aminoisophthalic acid as a maldi matrix for the detection of oligosaccharide additives in food

The application discloses application of 2-amino isophthalic acid (2-AIA) as a MALDI matrix in characterization of oligosaccharide additives in food. The skeleton structure of 2-AIA has a strong ultraviolet absorption group and a protonation site, which is beneficial to laser energy transmission and desorption ionization process of the measured object. Meanwhile, 2-AIA has multiple polar functional groups, which can effectively enhance the directional combination of the hydroxyl group of 2-AIA and oligosaccharide, and improve the anti-interference ability of impurities in a complex system. In addition, 2-AIA and a traditional organic matrix alpha-cyano-4-hydroxycinnamic acid (CHCA) are combined as a binary matrix (CHCA / 2-AIA), which can play a synergistic role of the double matrix, significantly improve the detection sensitivity of oligosaccharide. On the other hand, the combination of CHCA and 2-AIA with different pH values can significantly improve the uniformity of the co-crystallization, and improve the accuracy and reproducibility of quantitative detection.
Owner:ZHEJIANG UNIV

A barley agmatine coumaroyltransferase gene HvACT2 and its application in improving barley disease resistance

The present invention discloses an agmatine coumaroyl transferase gene HvACT2 and its application in improving the disease resistance of barley. The present invention clones and analyzes the barley agmatine coumaroyl transferase synthesis gene HvACT2 for the first time, confirms the function of the HvACT2 gene in the synthesis of hydroxycinnamic acid amide and malt guanidine by transgenic means for the first time, and finds that overexpression of HvACT2 can significantly improve the disease resistance of barley. The present invention also finds that HvACT2 has the function of catalyzing the synthesis of p-coumaroyl agmatine and feruloyl agmatine. The present invention also finds that the transient expression of HvACT2 synthesizes a variety of agmatine amides in tobacco, and tobacco does not originally have such substances, that is, the expression of exogenous genes causes tobacco to synthesize agmatine amides, and it is also found that the expression of HvACT2 in tobacco also increases the content of caffeoyl putrescine.
Owner:ZHEJIANG UNIV

Corrosion-resistant polypropylene insulated cable and preparation process thereof

The invention discloses a corrosion-resistant polypropylene insulated cable and a preparation process thereof, and belongs to the technical field of cables. The corrosion-resistant polypropylene insulated cable sequentially comprises a cable core, a wrapping layer, an inner sheath layer, an armor layer and an outer sheath layer from inside to outside, the inner sheath layer and the outer sheath layer are both made of a corrosion-resistant polypropylene cable material; the corrosion-resistant polypropylene cable material is prepared from the following raw material components: polypropylene, POE (Polyolefin Elastomer), a plasticizer, a composite flame retardant, a heat-conducting filler, a lubricant, an ultraviolet light absorber and a nucleating agent, the composite flame retardant is prepared from the following raw materials: cyanuric chloride, 4-hydroxymethyl-1-oxo-1-phospha-2, 6, 7-trioxabicyclo [2.2. 2] octane, hydroxyl N-alkoxy hindered amine, ethidene diamine and N-(2-aminoethyl) maleimide; the heat-conducting filler is prepared from the following raw materials: graphene oxide, a silane coupling agent, boron nitride and 3, 5-di-tert-butyl-4-hydroxycinnamic acid; the corrosion-resistant polypropylene insulated cable prepared by the invention is relatively good in corrosion resistance, heat dissipation performance, flame retardance, thermo-oxidative aging resistance and mechanical property.
Owner:CHANGFENG WIRE & CABLE +2

A method for simultaneously determining multiple index components in Wendan Tablets

The present invention provides a method for simultaneously determining multiple index components in Wendan Tablets. In this method, Wendan Tablets are used as test samples for high-performance liquid chromatography detection to simultaneously determine p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid in Wendan Tablets. The method of the present invention can also quantitatively determine the contents of the above four components in Wendan Tablets, and the quantitative determination methods include the external standard method and the multiple components by single marker method. The determination method of the present invention realizes the qualitative and quantitative determination of multiple components (p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid) in Wendan Tablets. Among them, the multiple components by single marker quantitative detection method not only ensures the quality, stability, and controllability of the preparation, but also reduces the detection cost of purchasing reference substances, achieving excellent technical effects and having broad application prospects.
Owner:ZHANGZHOU PIEN TZE HUANG PHARM

Rubber composition and pneumatic tire

PendingJP2026011113ASpecial tyresPolymer scienceMotorsports
To provide a rubber composition to be a raw material of a vulcanized rubber excellent in steering stability and wet grip performance when used as a rubber part of a pneumatic tire, especially a pneumatic tire for motor sports.SOLUTION: A rubber composition comprising 100 parts by mass of a rubber ingredient containing at least a diene rubber, 0.1 to 10 parts by mass of a cinnamic acid compound having a hydroxyl or methoxy group-substituted aromatic ring, and 40 to 140 parts by mass of carbon black having a nitrogen-adsorption specific surface area of 140 to 250m2 / g. The cinnamic acid compound is a naturally occurring compound and is preferably at least one of 3, 4-dihydroxycinnamic acid and 3, 4-dimethoxycinnamic acid.SELECTED DRAWING: None
Owner:TOYO TIRE CORP

Application of esterified derivative of methyl p-hydroxycinnamate in preparation of antitumor drugs

The invention relates to the technical field of biological medicine, in particular to application of esterified derivatives of methyl p-hydroxycinnamate in preparation of antitumor drugs. Experiments show that the derivative has an obvious inhibition effect on the cell viability of tumor cells such as gastric cancer, nasopharynx cancer and breast cancer, particularly has obvious proliferation, migration and invasion inhibition ability on the gastric cancer cells, can induce apoptosis of the gastric cancer cells, has relatively low toxic and side effects, and provides a new medicine for treating the gastric cancer.
Owner:CHONGQING MEDICAL UNIVERSITY

A composition comprising at least 5% by mass of titanium dioxide, an α-cyanodiphenyl acrylate derivative, and 4-hydroxybenzylidenemalonate or a 4-hydroxycinnamate derivative.

The present invention relates to a composition comprising: 1) at least one inorganic UV filter selected from titanium dioxide; 2) at least one α-cyanodiphenylacrylate derivative of the given formula; and 3) at least one 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative of the given formula. The present invention also relates to a cosmetic method for treating skin against UV radiation using said composition.
Owner:LOREAL SA

Superamolecular assembly and composition comprising the same

The invention provides a supramolecular assembly which comprises at least one hydroxycinnamic acid derivative and at least one betaine compound, and the betaine compound and the hydroxycinnamic acid derivative are assembled through non-covalent bond acting force. The invention also provides a cosmetic composition containing the supramolecular assembly and a method for preparing the supramolecular assembly.
Owner:ELC MANAGEMENT LLC

Polyester derived from biomass

The present invention provides a biomass-derived polyester compound useful as a rubber material or an adhesive material, the compound including a multiple bond in the molecule. By synthesizing an ester compound composed of a hydroxycinnamic acid and a fatty acid, and carrying out polycondensation reaction using the ester compound as a monomer, a polyester compound containing cinnamic acid and a ricinoleic acid derivative that are alternately linked to each other can be efficiently obtained. For example, an ester compound of General Formula (1) is produced. (In the formula, the substituents R1 and R2 each represent a hydrogen atom or a methoxy group; the substituent R3 represents an alkyl group or an alkenyl group; and n represents an integer of 10 to 100).
Owner:NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY

Enzymatic extraction method for a wild mountain ginseng-like product

The present invention discloses a method for enzymatic hydrolysis extraction of a wild ginseng-like product, belonging to the technical field of wild ginseng. Some rare saponins in wild ginseng can promote cell growth and division and improve the body. Through specific active enzymes, the prototype saponins can be enzymatically hydrolyzed to generate different rare saponins. In the present invention, through the action of radio frequency plasma, a mixed gas of α-linolenic acid vapor and nitrogen is used to treat the ultrafiltration membrane, thereby introducing double bond groups onto the ultrafiltration membrane; an esterification reaction occurs between p-hydroxycinnamic acid and cellulase to generate a product with reactive activity; these products undergo graft polymerization with the double bonds on the surface of the ultrafiltration membrane to form a more stable and more functional modified ultrafiltration membrane; the present invention can effectively separate and extract the target substances through a combination of enzymatic hydrolysis and ultrafiltration membrane fractionation; the molecular weight distribution of the peptides released during the enzymatic hydrolysis process is within a certain range, which helps to precisely separate these substances through the ultrafiltration membrane, and the extraction rate is high.
Owner:GUANGDONG SANGONG LIFE TECH CO LTD

Application of thymol combined with 4-hydroxycinnamic acid in the prevention and treatment of plant fusarium wilt

PendingCN122623662ASporelingSpore germination
The present application provides a kind of compound composition for preventing and treating plant wilt, the composition composition includes 4-hydroxy cinnamic acid and thymol, mass ratio is 1:1~1:2;The mass ratio of the composition is 1:1, the concentration of the composition is 60~300 μg / mL;The mass ratio of the composition is 1:2, the concentration of the composition is 50~200 μg / mL;The present application can inhibit the growth of pepper fusarium oxysporum f.sp.cubense mycelium, spore germination and sporulation, and can play a synergistic effect.The composition in the present application can significantly reduce the incidence of wilt in pot experiment.Compared with the prior art, the present application aims to reduce the use of chemical pesticides by low-cost, safe and efficient plant-derived antibacterial compounds.
Owner:INST OF PLANT PROTECTION HAINAN ACAD OF AGRI SCI (HAINAN ACAD OF AGRI SCI AGRI PROD QUALITY SAFETY & STANDARDS RES CENT)

Recombinant cells, extracts, consumable products and methods for production of bioactive plant metabolites

Disclosed herein are recombinant host cells and methods capable of producing tyramine-containing hydroxycinnamic amide compounds, derivatives, and extracts.SOLUTION: Some embodiments provided include, for example, consumable products containing tyramine-containing hydroxycinnamic acid amides produced by recombinant host cells. Some embodiments provided herein are methods for producing tyramine-containing hydroxycinnamic amide or hydroxycinnamic amide derivatives.SELECTED DRAWING: None
Owner:BRIGHTSEED INC

Skin care composition comprising peptide derivative and fatty acid, and method of using the same

A cosmetic skin care composition having a peptide derivative, a fatty acid having from about 8 to about 22 carbon atoms, and a dermatologically acceptable carrier. The peptide derivative has a formula: Rc-R1-Gly-Pro-Gln-Gly-R2, where Rc is chosen from hydroxycinnamic acid, its derivative, and mixtures thereof, where R1 and R2 are respectively from about 0 to about 8 amino acids, and wherein a total of R1 and R2 is 8 or less amino acids; The composition provides improved penetration of such peptide derivatives to skin.
Owner:PROCTER & GAMBLE CO

Flame-retardant thermoplastic resin and preparation method thereof

InactiveCN119899442APolymer scienceAntioxidant
The invention discloses flame-retardant thermoplastic resin and a preparation method thereof. The flame-retardant thermoplastic resin is prepared from the following components in parts by weight: 96-116 parts of thermoplastic resin, 19-23 parts of a flame retardant and 0.1-0.5 part of an antioxidant, and the flame retardant is modified magnesium hydroxide. The invention also discloses a preparation method of the flame-retardant thermoplastic resin composite material. The 3, 4-dihydroxycinnamic acid is used for modifying magnesium hydroxide, and the polarity of magnesium hydroxide is weakened, so that the dispersity of magnesium hydroxide in the thermoplastic resin is improved, and the flame retardant effect of magnesium hydroxide is enhanced. The prepared thermoplastic resin composite material has very good flame retardant property, can be used in the field of automobile household appliance materials, and has very good application prospects.
Owner:HEFEI GENIUS NEW MATERIALS CO LTD

Matrix solution, mass spectrometry method, storage medium, and determination method

A matrix solution used to be mixed with a sample in a matrix-assisted laser desorption / ionization mass spectrometry method. The matrix solution is an aqueous solution containing acetonitrile, ethanol, trifluoroacetic acid, and water. A content of the acetonitrile is 30 to 40 vol% based on the matrix solution. A content of the ethanol is 10 to 20 vol% based on the matrix solution. A content of the trifluoroacetic acid is 1 to 3 vol% based on the matrix solution. The matrix solution contains α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, or sinapinic acid in a ratio of 5 to 20 mg / ml.
Owner:SHIMADZU CORP

Acid liquid thickener and preparation method thereof

The present invention relates to the technical field of oilfields, and discloses a kind of acid liquid thickener and preparation method thereof, 3,4-dihydroxycinnamic acid, acrylamide, sodium olefin sulfonate modified boric acid, quaternized cardanol are added to water, mixed evenly, citric acid is continuously added to adjust pH, nitrogen is continuously introduced, and azobisisobutyronitrile, potassium persulfate, sodium pyrosulfite are added thereto, stirred for reaction, filtered after reaction, washed, and acid liquid thickener is obtained. The acid liquid thickener of the present invention contains adamantane and benzene ring rigid groups, improves the rigidity of the acid liquid thickener, thereby also enhancing its shear resistance and stability; wherein the quaternary ammonium salt group and the sodium sulfonate group improve the temperature resistance and shear resistance of the acid liquid thickener.
Owner:CHIFENG AOLONG CHEM CO LTD

Non-therapeutic use of hydroxycinnamic acid and derivatives

This invention generally relates to the use of hydroxycinnamic acid or its derivatives, such as alginate, in cosmetic or therapeutic settings. The invention further relates to compositions comprising hydroxycinnamic acid or its derivatives.
Owner:CYSBIO APS

Non-therapeutic and therapeutic use of hydroxycinnamic acid & derivatives

The present invention generally relates to the use of hydroxycinnamic acid or derivatives thereof, such as zosteric acid in a cosmetic or therapeutic setting. The present invention further relates to compositions comprising hydroxycinnamic acid or derivatives thereof.
Owner:CYSBIO APS

Use of hydroxycinnamic acid salts for stabilizing organic materials, stabilized organic materials, methods for stabilizing organic materials, specific stabilizers and stabilizer compositions

The present invention relates to the use of specific hydroxycinnamic acid salts for stabilizing organic materials. The invention also relates to the corresponding organic materials stabilized by incorporation of specific hydroxycinnamic acid salts and to methods for stabilizing organic materials. Furthermore, aluminum salts of specific hydroxycinnamic acids are described which are suitable as organic stabilizers. The invention also relates to stabilizer compositions comprising the corresponding hydroxycinnamic acid salts.
Owner:FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV

Process for preparing p-hydroxycinnamic acid

The present invention relates to a process for preparing para-hydroxycinnamic acid from para-hydroxybenzaldehydes by reaction with malonic acid in the presence of at least one of an amino acid and acetic acid. The process may include a condensation reaction between a para-hydroxybenzaldehyde compound with malonic acid in the presence of at least one of an amino acid and acetic acid.
Owner:SPECIALTY OPERATIONS FRANCE

Process of obtaining an extract of rosmarinus officinalis, extract of rosmarinus officinalis, use of an extract, dermocosmetic or pharmaceutical composition and method of treatment and / or prevention of alopecia

PCT designated stageWO2026137058A1AndrogenMechanism of action
The present invention relates to a method for obtaining an extract of the leaves of Rosmarinus officinalis (rosemary) involving two stages of maceration, filtration, concentration of the two drained products and drying, guaranteeing an extract comprising mainly hydroxycinnamic derivatives, rosmarinic acid, luteolin, neptin and carnosol, and the use of the extract in cosmetic compositions in the prevention and treatment of androgenetic alopecia, in which the extract of the invention acts through multiple mechanisms of action, and can be used in men and women.
Owner:ACHE LAB FARM

Modified polyester film for automobile window and preparation method of modified polyester film

The invention discloses a modified polyester film for an automobile window and a preparation method of the modified polyester film, and relates to the technical field of polyester films. When the modified polyester film for the automobile window is prepared, firstly, methyl p-hydroxycinnamate reacts with [chlorine (ethyoxyl) phosphonyl] benzene to prepare a modified phosphorus-containing cinnamic acid diester compound; the preparation method comprises the following steps: reacting nano antimony tin oxide with a silane coupling agent to prepare pre-modified nano antimony tin oxide; the pre-modified nano tin antimony oxide is subjected to a reaction with thiazolidine acid, 6-maleimido-1-hexanal and ethyl isocyano acetate, and modified nano tin antimony oxide is prepared; carrying out copolycondensation on terephthalic acid, ethylene glycol, the modified phosphorus-containing cinnamic acid diester compound, 2, 2 '-difuran-5, 5'-dicarboxylic acid dimethyl ester and the modified nano tin antimony oxide to obtain modified polyester; and carrying out hot-pressing film formation on the modified polyester to obtain the modified polyester film for the automobile window. The prepared modified polyester film for the automobile window has the advantages of flame retardance, ultraviolet shielding, heat insulation, self-repairing and aging resistance.
Owner:SHENGLEDI (JIANGXI) THIN FILM TECHNOLOGY CO LTD

Edible treatment composition for prolonging shelf life of mushrooms

An edible treatment composition is disclosed that includes non-toxic and harmless chemicals to extend the shelf life of mushrooms and maintain the freshness of the mushrooms over a long period of time during storage and transportation. The disclosed edible treatment compositions include kojic acid, L-arginine, hydroxycinnamic acid (HCA), and optionally other active or inactive ingredients, such as antibacterial agents, etc. The present invention relates to the treatment of mushrooms with the disclosed edible treatment compositions before or after harvest to extend their shelf life by imparting one or more characteristics over an extended period of time, such as maintaining whiteness, delaying browning, delaying pileus (cap) opening, better robustness, maintaining structural integrity, slowing weight loss, and the like.
Owner:NAVORK INNOVATIONS PTE LTD

Edible treatment composition for shelf-life extension of mushrooms

PendingUS20260083141A1Fruit and vegetables preservationBiotechnologyKojic acid
The present invention discloses an edible treatment composition comprising non-toxic and non-hazardous chemicals to extend the shelf-life and maintain freshness of mushroom for prolonged time during its storage and shipment. The disclosed edible treatment composition includes Kojic Acid, L-arginine, Hydroxycinnamic acid (HCA) and optionally additional active or inactive components like antimicrobial agent, etc. This invention is concerned with the treatment of mushroom with disclosed edible treatment composition, pre- or post-harvest, to extend its shelf-life by imparting one or more properties like, maintained whiteness, delayed browning, delated pileus (cap) opening, better firmness, maintained structural integrity, slower weight-loss, etc. for prolonged time, amongst others.
Owner:NAVORK INNOVATIONS PTE LTD