The invention discloses a
leucaena leucocephala-sourced
dihydrochalcone compound, a preparation method thereof and application of the
dihydrochalcone compound as a
tyrosinase inhibitor. According to the invention, the
tyrosinase inhibitor
dihydrochalcone compound (+ / -)-4, 4 '-Methoxy-3, 3', beta-trihydroxydihydroxychalcone is extracted and separated from the
leucaena leucocephala plant, the
structural formula of the compound is as shown in the formula (I), the
plant material is rich in source and is a renewable
tissue part, and not only is the economic benefit good, but also the environment-friendly effect is achieved. Pharmacological experiments show that the
tyrosinase inhibitory activity of the compound (+ / -)-4, 4 '-Methoxy-3, 3', beta-trihydroxydihydroxycholone is stronger than that of
kojic acid, and the compound (+ / -)-4, 4 '-Methoxy-3, 3', beta-trihydroxydihydroxycholone) is expected to be further developed into a new whitening cosmetic synergist, a
drug for treating pigmentation dermatosis, an
insect control agent or a food
preservative and the like, and has a good prospect.