313 results about "Kojic acid" patented technology

The objetive of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe and stable topical agents for dermatological use. For that purpose 4-Hydroxyphenyl-alpha-D-glucopyranoside was combined with auxiliary agents such as ascorbic acid and its derivatives, crude drugs and its extracts, hydroxycarboxylic acid and its salts, oil soluble glycyrrhiza extract, gentian extract, phenol derivatives and their salts, placenta extract, kojic acid and its derivative, glucosamine and its derivatives, azelaic acid and its derivatives, retinol and its derivatives, pyridoxin and its derivatives, tocopherol and its derivatives, chitosan and its decomposition products, caffeic acid derivatives, hydroxycinnamate and its derivatives, Umbelliferae plant extracts, mycelial cultures and their extracts, plant leaves and their extracts.

A sheet for whitening cosmetics comprises a sheet-like substrate and an adhesive layer which comprises a wet pressure-sensitive adhesive composition formed on the substrate. The whitening component includes vitamin C or its derivatives such as magnesium L-ascorbyl-2-phosphate, vitamin E nicotinate, kojic acid, hydroquinone, ellagic acid, albumin, galenical extracts, and rice bran extracts. Kojic acid and magnesium L-ascorbyl-2-phosphate are preferred. By contacting the adhesive layer with water and/or a hydrophilic medium such as alcohols, e.g., methanol, ethanol, etc., the wet pressure-sensitive adhesive composition exhibits excellent stickiness and excellent applicability to skin as well as excellent whitening effect with alleviating or eliminating stains, freckles, non-transparency, etc. on the skin.

A cosmetic skin-care composition containing as the active principle a depigmentationally active combination of (a) an acidic mixture including (i) at least one alpha-hydroxylated acid or a derivative thereof, with the exception of ascorbic acid, and (ii) at least one compound selected from the group which consists of kojic acid, caffeic acid, azelaic acid, aminobutyric acid, fusaric acid, 5-hydroxy 2-hydroxymethyl-gamma-pyridone, and derivatives thereof, and (b) at least one active component of a plant extract from at least one plant selected from white mulberry, liquorice, skull cap, grapefruit, birch, heather, strawberry tree, bearberry, lemon, lettuce, oarweed, cucumber, ginseng, hop, sweet corn, feverfew, sage, soya, elder, spirulina, lime, ferocious aloe, yukinoshita, bloodwort, hoelen, wood rose, alpha-orizanol, burnet, ginkgo biloba, tanlex VB and Eclipsa alba, with the proviso that when the composition contains kojic acid and a liquorice extract, it contains at least one other plant extract component. The use of said composition for preparing a drug or in a cosmetic method is also disclosed.

The invention discloses boiled lotus root slice processing technology and a product thereof, and belongs to the technical field of food processing. The technology is characterized by comprising the following steps of: soaking a lotus root in solution consisting of citric acid and kojic acid for 0.5 to 2 hours after washing, selecting and peeling; pickling the lotus root in the solution of salt at 18 to 22 degree Be' for 5 to 10 days; cutting and desalting the lotus root after pickling; boiling the cut lotus root in 0.3 to 0.5 mass percent of calcium lactate solution at the temperature of between 80 and 85 DEG C for 12 to 15 minutes; sorting, packaging and adding decoction which is formed by mixing the citric acid, malic acid, lactic acid, and ascorbic acid and contains 0.3 to 0.5 mass percent of the calcium lactate; and obtaining the product by vacuumizing, sealing, sterilizing and cooling. Boiled lotus root slices prepared by the technology have the characteristics of milky color and luster, tender and crisp texture, safety and sanitation, and convenient eating.

The invention provides a facial make-up with excellent effect on moisturizing, whitening and nourishing and small irritation to skin. The facial make-up consists of make-up substrate and make-up active substances, wherein the make-up active substances comprise glycolic acid, kojic acid, arbutin, aloin, baicalin, paeoniflorin, glycyrrhizic acid, squalane, hyaluronic acid and chitin to be prepared into toner, facial cream, facial cleanser, facial mask, gel and external soft capsule preparations.

A composition is described that comprises moringa oils, or its derivatives, produced from the moringa plant in combination with an oxidation stabilizing system comprising at least one tocopherol. The oils derived from the moringa plant should have a percent methylene interrupted unsaturation of less than 1%. The composition may have at least one supplemental additive, such as malic acid, kojic acid, or ascorbic acid, present in an amount of from 0.01 to 2% or more by weight of the composition and the tocopherol is present in an amount of from 0.01 to 5% by weight of the composition.

The invention discloses health-care bath salt and a preparation method thereof. The health-care bath salt comprises the following components in percentage by weight: 40 to 60 percent of salt, 0.2 to 8 percent of safflower, 0.2 to 8 percent of common bletilla pseudobulb, 0.3 to 8 percent of ginkgo, 5 to 10 percent of surfactant, 0.2 to 8 percent of kojic acid, 0.1 to 8 percent of spice and 0.7 to 10 percent of ethanol. The finished health-care bath salt is prepared by processes such as grinding, mixing, conditioning and the like. The bath salt avoids a defect that bulk salt has high fluidity; meanwhile, salt granules are controlled to avoid scratching the skin during use; in addition, Chinese medicinal materials with health-care functions are added, and through the synergism of the medicinal materials and the salt, the health-care bath salt can achieve the effects of killing bacteria and diminishing inflammation, expelling toxin and removing odor, relaxing muscles and promoting blood circulation, moistening skin, beautifying and whitening, and the like, and is suitable for female.

Cosmetic preparations are disclosed, containing: (a) extracts of Waltheria indica and (b) ascorbic acid, ferulic acid and/or kojic acid.

The invention provides a green vegetable compound antistaling agent and a matched antistaling method thereof. The method is characterized by comprising the following steps of: (1) selecting fresh and complete green vegetables without disease, removing impurities, and washing with running water; (2) immersing the drained vegetables in the green vegetable compound antistaling agent compounded by sodium erythorbate, kojic acid, gibberellin, salicylic acid and magnesium sulfate for 15 minutes, and drying by using cold air; and (3) packaging the vegetables in a freshness protection package specialfor green vegetables with air-regulating and humidity-breathing function, fastening the package mouth, putting into a packing box and storing at proper temperature, wherein the vegetables in each package do not exceed 2kg and the weight is consistent. The green vegetable compound antistaling agent can make the green vegetables stored at low temperature for 10 to 15 days or keep the color, freshness and mouthfeel of the vegetables in normal-temperature shelf life of 3 to 6 days, and is safe and nontoxic; and the method is simple and has promotion and application value.

The invention discloses a novel fresh-keeping composition for fruits and vegetables. The novel fresh-keeping composition comprises the following components in percentage by weight: 1-5 parts of kojic acid and 0.1-0.5 parts of phytic acid. The invention further discloses application of the fresh-keeping composition for the fruits and the vegetables and a novel fresh-keeping agent for the fruits and the vegetables. The fresh-keeping composition for the fruits and the vegetables, which is disclosed by the invention, has the advantages of excellent fresh-keeping effect, safety, low cost and favorable industrial prospect.

The present invention relates to topical skin whitening compositions comprising a whitening effective amount of a black yeast-derived melanin-degrading enzyme extract and a method of preparing the compositions. The compositions provide a whitening effect by degrading melanin on the surface of the skin, the hair and the nails. The enzyme extract can be derived from Exophiala mansonii. The compositions containing the enzyme extract are more effective than are similar compositions containing kojic acid in producing a whitening effect on the skin.

The invention discloses a chitosan oligosaccharide kojic acid derivative and a preparation method thereof. The chloro kojic acid is mainly reacted with C2-amino(-NH2) of chitosan oligosaccharide to generate a chitosan oligosaccharide derivative, the obtained derivative is analyzed and confirmed by using an infrared spectrum and 1H nuclear magnetic resonance, and the chitosan oligosaccharide molecule is effectively combined with inoculated groups to form the chitosan derivative, wherein the reacted amino groups account for 24.15-55.68% of the total amount of amino in chitosan oligosaccharide. The prepared chitosan oligosaccharide kojic acid derivative is good in solubility and strong in bacteriostatic activity and can be used as a preservative to be widely applied to the fields of medicines and foods.

The invention provides a nutritional preparation with selective whitening spot-removing efficacy and application thereof in medicinal cosmetics. The nutritional preparation is prepared by compounding of azelaic acid oligopeptide, ascorbic acid oligopeptide, tranexamic acid oligopeptide, retinoic acid oligopeptide, kojic acid oligopeptide, hydroxy acid oligopeptide, ellagic acid oligopeptide and other raw materials, and the oligopeptide is one or a compound of multiple of dipeptide, tripeptide, tetrapeptide, pentapeptide, hexapeptide, heptapeptide, octapeptides, nanopeptide and decapeptide. The medicinal cosmetics prepared form the nutritional preparation are original liquids, water preparations, masks, cream lotion, liquid foundation cream, gel, essence and other preparation forms. The cosmetics are prepared by compounding of the nutritional preparation, penetrating agents and auxiliary materials. The penetrating agents are plant essential oils, azone, carbitol and other medical penetrating agents. The auxiliary materials are thickeners, emulsifiers, packet agents, wetting agents, emollients, flavoring agents, preservatives and solvents which are used as main medicinal raw materials. A large number of clinical trials prove that the medicinal cosmetics prepared form the nutritional preparation have good selective whitening spot-removing and nutritional efficacy for the skin of human body.

Polyelectrolyte based bioactive super-absorbent material ionotropically crosslinked/neutralized involving polyvalent carboxylic acids, citrate, Kojic Acid, Alpha Arbutin along with fish scale collagen cross linked with other polyelectrolyte biopolymers preferably selected from chitosan, alginate or their combinations is used in this invention. The advancement is also directed to process of extraction of collagen of high purity from fresh water fish scale by salt and alkaline washing, crushing followed by continuous dialysis thereby minimizing the chance of collagen degradation. Also disclosed are different forms of collagen-chitosan composite biomaterial using citrate as the neutralizing buffer in combination with antimicrobial agent, antioxidant, skin plumper and melanin reducer wherein the different forms of collagen chitosan particularly sheet, flakes, powder, gel, particles, fiber, film, spray etc. reveal efficient wound healing properties. The advancement is thus directed to find wide application in various dermal wound healing, tissue engineering, 3D cell culture, cell expansion and cell delivery vehicle, mimicking the in vivo situation in dynamic condition, cosmetics and different other health care applications.

The invention discloses a method for brewing cherry fruit wine. The method is characterized by comprising the following steps of: after selecting, washing and stoning cherries serving as raw materials, obtaining primary pulp by juicing; adding the following substances such as pectinase, calcium citrate, vitamin C, and g/L kojic acid into the primary pulp; standing for 5 to 24 hours; preparing clear juice by performing centrifugal separation; inoculating 0.05 to 2 percent of fruit wine yeast based on the weight of the clear juice; controlling a temperature and fermenting, wherein the primary fermentation temperature is between 16 and 28 DEG C, the fermentation time is 7 to 15 days, the secondary fermentation temperature is between 15 and 20 DEG C, and the fermentation time is 20 to 40 days; aging for 3 to 6 months; clarifying and filtering by adopting an ultra-filtration method; and filling, sterilizing and packaging to obtain finished cherry fruit wine. The method effectively improves a production process of cherry wine, reduces the content of polyphenol fundamentally, inhibits the activity of polyphenol oxidase, reduces harsh taste and improves stability. Compared with the prior art, the cherry fruit wine produced by the method maintains effective nutrient components, reduces the harsh taste and has a pure flavor.

A dermal topical formulation containing p-menthane-3,8-diol and a whitening component such as arbutin, kojic acid, ellagic acid, ascorbic acid or its derivative, lactic acid, glycolic acid, tartaric acid, and an essence or an absolute extracted from a plant such as labdanum, jasmine and mugwort (T.vulgare). The dermal topical formulation is highly safe and capable of promoting the percutaneous absorption of the whitening component.

The invention discloses anti-ultraviolet mask liquid, which is obtained by impregnating mask paper into liquid prepared from the following raw materials in parts by weight: 0.1-3 parts of small molecular hyaluronic acid, 1-5 parts of macromolecular hyaluronic acid, 0.7-30 parts of synthetic egg white powder, 5-10 parts of aloe extract, 0.7-9 parts of propylene glycol, 5-50 parts of 1,2-butanediol, 5-30 parts of glycerin, 20-50 parts of ginseng extract, 40-80 parts of radix scutellariae extract, 10-50 parts of licorice extract, 5-10 parts of kojic acid, 5-30 parts of nano water-soluble titanium dioxide, 1-5 parts of raspberry ketone glucoside, 1-10 parts of vitamin C ethyl ether and the balance of water added till the total volume is 1000 parts. The components of the mask liquid are appropriate in selection and reasonable in coordination, and are synergistic from different mechanisms to achieve the anti-ultraviolet effect, so that the mask liquid can reduce the transmission of ultraviolet and repair skin injury caused by ultraviolet, and has double-protection effect, better effect and very good anti-allergic function.

A nanometer solid lipid carrier covering kojic acid dipalmitate is disclosed. The nanometer solid lipid carrier comprises 1-25% by weight of the kojic acid dipalmitate, 0.1-5% by weight of phospholipid, 2-15% by weight of solid lipid, 3-20% by weight of liquid lipid, 3-20% by weight of a solid emulsifying agent, 2-20% by weight of a polyalcohol additive and 0.01-0.8% by weight of a preservative, with the balance being deionized water. A preparing method of the nanometer solid lipid carrier is also provided. The preparing method includes: melting an oil phase comprising the kojic acid dipalmitate, the phospholipid, the solid lipid, the liquid lipid and the solid emulsifying agent at 75-95 DEG C and uniformly dispersing to obtain an oil phase; heating a water phase comprising the deionized water and the polyalcohol additive to 75-95 DEG C; stirring the water phase and adding the oil phase; performing high-pressure homogenization after uniform mixing; and stirring and cooling to form the nanometer solid lipid carrier. The nanometer solid lipid carrier and the preparing method promote permeation of the kojic acid dipalmitate on skin, increase the utilization rate, and enhance the whitening effect.

The invention discloses an antioxidant with a function of inhibiting melanin production as well as a preparation method and use of the antioxidant. The antioxidant is a polysaccharide component FMP separated out from morchella esculenta, and has a molecular weight of 4.5kDa; the monosaccharide composition mainly is prepared from mannose, glucose and galactose. The polysaccharide component FMP obtained by the method has good in-vitro free radical scavenging ability; in vitro and in vivo experiments prove that the polysaccharide component FMP can inhibit the melanin production and tyrosinase activity well, and does not have obvious toxic and side effects; the tyrosinase inhibition activity of the polysaccharide component FMP is comparable to that of kojic acid; therefore, the polysaccharidecomponent FMP can be used as a natural high-efficiency antioxidant and a melanin production inhibitor, and has a great application prospect in the fields such as food and cosmetics.

The invention discloses pericarp residue brandy. The pericarp residue brandy is prepared from the following raw materials: fresh grapes, rape pollen, momordica cochinchinensis, haematococcus pluvialis, green tea, Chinese angelica, sucrose, Angel wine yeast, lycopene, carotene, honeysuckle extract, xanthophyll, kojic acid, pectinase, lipase, protease and lysozyme. The pericarp residue brandy provided by the invention has comprehensive nutrients, can be easily prepared, is mellow and aromatic and has a high health function; the pericarp residue brandy is prepared by low-temperature fermentation, so that the growth of infectious microbes is obviously inhibited and poor metabolites are avoided; flavors and nutrients of the raw materials are kept; pericarps are subjected to primary and secondary fermentation, and fruits, vegetables and traditional Chinese medicines which have the health function are added to adjust the ratios of a primary fermentation solution to a secondary fermentation solution, so that the flavor and nutrients of the brandy are increased and the stability of wine is enhanced; an extraction process of the fruits, the vegetables and the traditional Chinese medicines is simplified, the extraction rate is improved and the cost is saved; the health function is enhanced; the pericarp residue brandy has the effects of preventing and resisting cancers, maintaining beauty and protecting skins, delaying ageing, enhancing the immunity and resisting oxidization.

The invention discloses a compound preservative for strawberry. The compound preservative comprises the following components in percentage by weight: 1% of chitosan, 0.81% of kojic acid, 0.36% of calcium chloride, 0.03% of natamycin and 97.8% of water. The invention further discloses a method for processing strawberries by using the compound strawberry preservative; the method comprises the following steps: (1) selecting strawberries and washing with water; (2) immersing the drained strawberries in the compound preservative for 1 minute, taking out the strawberries, and naturally drying; (3) putting the strawberries in a fresh-keeping tray, covering the strawberries with a preservative film, and storing at room temperature. The compound strawberry preservative provided by the invention can be used for effectively reducing the loss of external composite index, respiration intensity, titratable acid, soluble solids and sugar content of strawberry, and preventing rot; the compound preservative which can be used for processing the strawberries is high in safety, pollution-free and easy to clean; and the method is a safe and efficient fresh keeping method.

The present invention relates to a production process of kojic acid and belongs to the preparation of oxygenous organic compound. The production process includes liquefying and saccharifying starch in a fermenting tank; inoculating to sterilized saccharide liquid to culture kojic acid via fermentation; and refining kojic acid through concentration and crystallization of kojic acid liquid, dissolving crystallized product, decoloring, cooling and crystallization to obtain kojic crystal. The product is homogeneous crystal with purity over 98%.