The invention provides freeze-dried 
powder having whitening activity and a preparation method and application of the freeze-dried 
powder. The freeze-dried 
powder consists of 
tranexamic acid, 
nicotinamide, 
mannan and 
ascorbyl glucoside. The freeze-dried powder can effectively lighten 
melanin; after being used for a long term, the freeze-dried powder can brighten 
skin color and whiten 
skin; the freeze-dried powder is free from 
chemical preservatives, does not stimulate the 
skin, is stable, does not 
change color, and is high in product activity, safe and effective. The invention also provides a preparation method of the freeze-dried powder. The freeze-
drying time can be effectively shortened, the freeze-dried powder is energy-saving and environmentally-friendly, the production cost is reduced, and a freeze-dried powder product which is good in shaping effects, firm in appearance, high in redissolution speed and good in solution 
clarity can be prepared. Besides, the freeze-dried powder canalso be directly added to other 
cosmetics in a liquid preparation formulation, such as essence and 
moisturizer to dissolve for use, and can also mutually dissolve with a 
solvent to be added to 
cosmetics in a 
solid preparation formulation, such as 
moisturizing cream, to be uniformly stirred for use, so as to reinforce effects, and a new development thinking is provided for development of whiteningproducts.