39 results about "ASCORBYL DIPALMITATE" patented technology

A complex consisting of lipoic acid or a salt thereof, a chelating agent such as a salt of ethylene diamine tetraacetic acid (EDTA) or analogous compounds and an ester of ascorbic acid with long-chain fatty acids, in particular ascorbyl palmitate inhibits the pigmentation of teeth induced by chlorhexidine and salts thereof. In addition to the depigmenting complex, the formulations of the invention, in the form of gels, mouthwashes, toothpastes or periodontal sprays, may contain other ingredients such as hyaluronic acid or hyaluronates, glycerophosphocholine, sweeteners, flavourings, buffering agents, viscosifying agents, mucoadhesive and filming agents, solvents, co-solvents, surfactants.

The invention belongs to the technical field of resveratrol synthesis, and particularly relates to a preparation method of resveratrol and application of resveratrol in meat preservation. The method comprises the following steps: taking 3, 5-dimethoxybenzoic acid as a raw material, and carrying out acylation reaction to obtain 3, 5-dimethoxybenzoyl chloride. Then reacting with p-acetoxystyrene to generate 3, 3 '-dihydroxy-3, 3'-dihydroxy-3 The preparation method comprises the following steps: taking 1, 5-dimethoxy-4 '-acetoxystilbene as a raw material, hydrolyzing and demethylating to obtain resveratrol, and preparing resveratrol lipid nanoparticle suspension by taking resveratrol, a ZIF-8 / chitosan compound, compound lipid, cholesterol, epsilon-polylysine, ascorbyl palmitate and phosphate buffer saline as raw materials. High load and controlled release of resveratrol are achieved, and the problems that resveratrol is poor in water solubility and prone to oxidation are solved.

This rotigotine-containing adhesive patch comprises a support layer and an adhesive layer, wherein the adhesive layer contains: at least one selected from the group consisting of rotigotine and pharmaceutically acceptable salts of rotigotine; a rubber-based adhesive base; and an antioxidant. The antioxidant includes propyl gallate, ascorbyl palmitate, and sodium pyrosulfite.

The application belongs to the technical field of biological medicine and medical cosmetology, and particularly relates to a kind of composition for mitochondrial protection type cosmetology and skin repair based on hydrogel and application thereof, the composition comprises a mitochondrial protection system and a synergistic active ingredient, the mitochondrial protection system comprises a hydrogel and a mitochondrial protection solution, the hydrogel comprises a synthetic polymer, and the mitochondrial protection solution comprises 200-300 mM mannitol, 0.2-5 mM ATP and 0-5% w / v trehalose; the synergistic active ingredient comprises a mixture of one or more of 0.01-0.1% ascorbyl palmitate, 0.1-1 mM glutathione and 0.5-2% nicotinamide. The composition is applied to microneedle repair, ice needle patch preparation and mask preparation and other aspects; through microneedle repair, ice needle patch or mask and other forms, effective delivery of mitochondria is realized, all-round care and repair are provided for the skin, and the delivery capacity is improved.

This invention discloses a soothing and repairing composition and its application, comprising the following raw materials: phytosterols, chamomile extract, hydrolyzed sodium hyaluronate, tocopherol, ceramide NP, triethanolamine, lactobacillus, macadamia seed oil, magnolia alcohol, matricaria flower extract, maltodextrin, lecithin, phosphatidylcholine, ascorbyl palmitate, inulin root juice, arginine / lysine polypeptide, squalane, jojoba seed oil, scutellaria baicalensis root extract, polygonum cuspidatum root extract, fructose, glycerin, p-hydroxyacetophenone, butylene glycol, acrylate / C10-30 alkanol acrylate crosspolymer, α-glucan oligosaccharide, 1,2-hexanediol, and water as the balance. Compared with the prior art, the soothing and repairing composition prepared by this invention has the effects of rapidly rebuilding the skin barrier, regulating skin immune function, improving skin microecology, synergistic effect, and rapid skin repair.

The invention discloses a method for improving the detection recovery rate of ascorbyl palmitate in a compound product, which comprises the following steps: taking a sample, adding BHT (butylated hydroxytoluene), then adding an isopropanol-n-hexane mixed solution containing 0.8-1.2% by volume of glacial acetic acid as an extraction solvent, then fully mixing, extracting, freezing, centrifuging, taking supernate, and collecting the supernate to obtain the ascorbyl palmitate. The chromatographic conditions are as follows: a C18 reversed-phase chromatographic column is adopted, a mobile phase A and a mobile phase B are used for gradient elution, the flow velocity of the mobile phase is 0.8-1.2 mL / min, the column temperature is 28-32 DEG C, and the maximum absorption wavelength of ascorbyl palmitate is taken as the detection wavelength. According to the method, the extraction efficiency is improved by optimizing a sample pretreatment process, and the problem that the liquid phase detection error of the substance in the compound product is generally higher than 10% is effectively solved in combination with improved high performance liquid chromatography separation conditions.

The invention relates to eye drops containing umbilical cord mesenchymal stem cell exosomes. The eye drops are prepared from the following raw materials: sodium hyaluronate, an L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound, panthenol, a solution containing the umbilical cord mesenchymal stem cell exosomes, water and normal saline, the concentration of the sodium hyaluronate is 0.2 to 0.6 mg / mL; the concentration of the L-ascorbyl palmitate / hydroxypropyl-beta-cyclodextrin inclusion compound ranges from 0.1 mg / mL to 0.4 mg / mL; the concentration of the panthenol is 0.2 to 1.0 mg / mL; the concentration of the umbilical cord mesenchymal stem cell exosome is 0.2 * 10 < 10 >-0.6 * 10 < 10 > parts / mL. The eye drops have good effects on treating xerophthalmia and repairing corneal epithelium injury.

The invention provides a thermo-sensitive hydrogel containing alpha-isoterpinene and a preparation method of the thermo-sensitive hydrogel, and the hydrogel comprises the following components: Te with the content of 0.1-5.0% (w / w); the temperature-sensitive matrix is composed of poloxamer 407 (15-25% w / w) and poloxamer 188 (2-10% w / w), and the mass ratio of the poloxamer 407 to the poloxamer 188 is (2.5-7.5): 1; the antioxidant system comprises ascorbyl palmitate (0.05-0.2% w / w), at least one of tocopherol, rosmarinic acid ester or pharmaceutically acceptable derivatives of the rosmarinic acid ester, and the balance of water. The traditional Chinese medicine composition is used for safely and effectively treating acnes. Belongs to the field of pharmaceutical preparations.

The application relates to the field of biological medicine, and discloses ascorbyl palmitate nanoliposomes capable of inducing tumor cell oncosis, a preparation method and application thereof. The nanoliposomes are constructed by inserting ascorbyl palmitate as a lipid component into a phospholipid bilayer, and are prepared by a film dispersion method from lecithin, cholesterol, pegylated phospholipid and ascorbyl palmitate. The average particle size of the nanoliposomes is 80-150 nm, the encapsulation rate is high, and the stability is good. The nanoliposomes can be administered through a tail vein, utilize the specific hydrolysis of matrix metalloproteinase MMP-2 which is highly expressed by tumor cells to hydrolyze ascorbyl palmitate, release palmitic acid and ascorbic acid, thereby inducing Caspase-independent oncosis of tumor cells, effectively overcoming apoptosis-related drug resistance, and reversing a tumor immunosuppressive microenvironment. The nanoliposomes avoid the cumulative toxicity of metal-type inducers, and provide a new safe and effective option for reversing chemotherapy resistance.

The invention discloses a rhizoma polygonati anti-aging extract and a preparation method thereof. The method comprises the following steps: pre-treating raw materials by adopting a composite cleaning agent containing green tea polyphenol and a ginger extract; soaking with a sugar protecting agent containing fructo-oligosaccharide and L-ascorbyl palmitate; carrying out nine-steaming nine-drying treatment after gradient ultrasonic cleaning, and recovering polysaccharide in condensed water through spiral condensation, centrifugation and ceramic membrane filtration in the steaming process; the preparation method comprises the following steps: extracting with hot water, heating and concentrating, mixing the obtained extract with polysaccharide recovered from condensed water, compounding with a cistanche deserticola extract according to a ratio of 3: 2, mutually dissolving with a composite cosolvent, carrying out gelatin-Arabic gum microencapsulation, and finally granulating with a slow-release matrix. According to the invention, the problems of loss of pretreatment polysaccharide, waste of active ingredients of condensed water, poor stability of terminal products, asynchronous release and the like are solved through a full-chain technology, and the retention rate, the stability and the anti-aging synergistic effect of the active ingredients are remarkably improved.

The invention discloses a method for rapidly detecting dichlorvos on site based on scattering turbidity, and belongs to the technical field of food and agricultural product safety detection. The method comprises the following steps: incubating dichlorvos with different concentrations with candida antarctica lipase, a phosphate buffer solution and L-ascorbyl palmitate, centrifugally incubating to obtain a reaction solution, taking a supernatant to react with a manganese dioxide nanosheet, measuring the turbidity of the reaction solution through a portable turbidimeter, and establishing a linear equation of the concentration and the turbidity of the dichlorvos; by measuring the turbidity of an unknown sample, the concentration of the dichlorvos can be calculated according to a linear equation. According to the method, invisible dichlorvos concentration signals are converted into measurable turbidity signals by utilizing the synergistic effect of enzyme inhibition reaction and turbidity change induction of the nano material, so that rapid and sensitive detection of dichlorvos is realized. The method is easy and convenient to operate, low in cost, high in detection speed, free of large instruments and especially suitable for on-site rapid screening of agricultural products.

Stabilized oils including an edible oil and an antioxidant composition comprising α-lipoic acid and least one of ascorbic acid, ascorbyl palmitate, green tea extract, lecithin, and rosemary extract or at least one of 1,2,4-benzenetriol, carnosic acid, dihydromyricetin, dihydrorobinetin, epigallocatechin, gallic acid, 3-hydroxytyrosol, myricetin, and nepodin, and methods of preparing such stabilized edible oils. The stabilized oils may have an Oxidative Stability Index (“OSI”) at 110° C. of at least 30 hours.

The present invention relates to atopical detergent composition comprising ascorbyl glucoside and ascorbyl palmitate, a washing and transcutaneous absorption-promoting base comprising at least one non-ionic surfactant, at least one anionic surfactant, glycerol, in combination with suitable excipients and / or diluents.

Emulsions for oral and cosmetic formulations free from sorbitan polyoxyethylene ethers esterified with fatty acids, comprising: a) a hydropolyol phase b) an oil phase; c) emulsifying agents; d) at least one water-soluble polysaccharide of plant origin; e) at least one lipophilic or hydrophilic active agent or a plant extract; wherein said hydropolyol phase a) comprises at least water, a polyol and a base the emulsifying agents c) consist of c1) ascorbyl palmitate and c2) at least one sucrose ester of fatty acids These emulsions are characterized by having the dispersed phase consisting of micelles of average size comprised between 90 and 800 nm measured by Dynamic Light Scattering (DLS).

The invention relates to nutritional soft sweets containing lutein ester microcapsule powder and a preparation method of the nutritional soft sweets. The soft sweets comprise the following raw materials in percentage by weight: 15-20% of lutein ester microcapsule powder, 60-70% of soft sweets matrix, 1-3% of auxiliaries and the balance of drinking water, the lutein ester microcapsule powder is prepared from the following raw materials in percentage by weight: 10 to 15 percent of lutein ester crystals, 10 to 12 percent of vegetable oil, 0.5 to 1 percent of ascorbyl palmitate, 8 to 12 percent of starch octenyl succinate, 5 to 8 percent of succinylated black bean protein, 1.5 to 2.5 percent of blueberry polysaccharide and the balance of drinking water. The soft sweets provided by the invention can realize long-acting stability of lutein ester, and finally guarantee persistence of an eye protection effect.

The present application relates to natural product separation and extraction technical field, specifically disclose a kind of method for separating and extracting astaxanthin with haematococcus pluvialis as raw material, comprising the following steps: (1) haematococcus pluvialis pretreatment preparation haematococcus pluvialis dry powder;(2) using ultrasonic-assisted natural deep eutectic solvent separates and extracts astaxanthin from haematococcus pluvialis dry powder and obtains crude extract;(3) using macroporous resin dynamic adsorption crude extract and purifying and collecting astaxanthin eluate;(4) astaxanthin eluate is concentrated by rotary evaporation under reduced pressure, freeze-dried, and astaxanthin crystal powder is obtained.The method provided by the present application effectively improves the extraction rate of astaxanthin by the ternary synergy of natural deep eutectic solvent, the trans-phase antioxidant synergy of tocopherol and ascorbyl palmitate, and the mild process of ultrasonic-assisted extraction and resin gradient elution, maintains the purity of astaxanthin and the proportion of all-trans astaxanthin, and prolongs the antioxidant retention time of astaxanthin.

Disclosed are topical compositions comprising hyaluronic acid or salts thereof and iota-carrageenan, preferably in a mucoadhesive matrix containing ascorbyl palmitate and choline alfoscerate. The compositions according to the invention are useful for topical treatment of Herpesvirus infections.

The invention provides a ceftiofur injection as well as a preparation method and application thereof, and belongs to the technical field of veterinary drug preparations. The ceftiofur injection prepared by the invention takes propylene glycol as a solvent, and every 1000 mL of the ceftiofur injection is prepared from the following components: 80 to 120 g of ceftiofur hydrochloride, 50 to 80 g of hydroxypropyl-beta-cyclodextrin, 180 to 220 mL of polyethylene glycol 400, 40 to 60 mL of medicinal glycerol, 2 to 5 mL of laurocapram and 0.8 to 1.2 g of ascorbyl palmitate. The ceftiofur injection prepared by the invention has the advantages that the plasma concentration peak reaching time is obviously shortened, the drug concentration of an infected part is obviously improved, the drug action time is effectively prolonged, the drug resistance risk of bacteria is reduced, the survival rate of piglets can be obviously improved, and the death risk caused by bacterial infection is effectively reduced; the method is suitable for prevention and control of secondary bacterial infection of the porcine reproductive and respiratory syndrome in large-scale pig

The invention discloses a preparation method and application of high-oxidation-resistance copper paste, and belongs to the technical field of solar cells. In order to solve the problem that the conductivity is reduced due to the fact that copper powder is extremely easy to oxidize in an environmental atmosphere, the invention provides a solution that the conductive paste comprises 73-90% of conductive powder and 10-15% of a dispersion carrier based on 100% of the total mass of the conductive paste; wherein the conductive powder is copper powder modified by antioxidant such as VC, ascorbyl palmitate, ascorbyl glucoside or glucose. Stable sintering in a non-high-purity nitrogen environment (the oxygen content is 2000 ppm) is achieved, and the use efficiency of the copper paste on an HJT battery reaches 24.2% and is equal to that of silver-coated copper; in the application of TOPCON battery overprinting, the efficiency is only less than 0.05% lower than that of pure silver, the efficiency attenuation is less than 0.1% after a bare chip is placed at room temperature for one month, the silver can be saved by 80%, and the cost of the photovoltaic slurry is greatly reduced.

The application discloses a process method for co-production of L-ascorbyl palmitate and biodiesel, which comprises the following steps: performing a first enzyme catalysis reaction on L-ascorbic acid and palm oil to obtain a first enzyme catalysis mixture; performing layer separation and vacuum distillation treatment on the first enzyme catalysis mixture to obtain a first enzyme catalysis product; performing a second enzyme catalysis reaction on the first enzyme catalysis product to obtain a second enzyme catalysis mixture; and performing distillation treatment on the second enzyme catalysis mixture under online dehydration conditions to obtain L-ascorbyl palmitate and biodiesel; the application utilizes the solubility of L-ascorbic acid in short-chain alcohol, promotes mutual solubility of L-ascorbic acid and palm oil, adopts two-step enzyme catalysis reaction under mild conditions, realizes reaction of L-ascorbic acid and palm oil catalyzed by lipase to generate L-ascorbyl palmitate, and realizes reaction of palm oil and short-chain alcohol catalyzed by lipase to generate biodiesel, so that integrated co-production of various high-value-added products is realized.

The application belongs to the field of plant growth regulators, and discloses a low-residue selective fruit tree chemical thinning composition and a preparation method thereof.The composition comprises, in percentage by mass, 6-12% of active ingredients, 3-8% of environmentally-friendly additives, 1-3% of degradation promoters, and 77-89% of solvents.The active ingredients are a compound of 6-benzylaminopurine and ammonium acetate, the environmentally-friendly additives are a mixture of sodium docusate and methyl oleate, the degradation promoters include L-ascorbyl palmitate, a fatty acid ester derivative, polyaspartic acid or nano titanium dioxide, and the solvents are a mixture of deionized water and ethanol.The composition has the characteristics of good thinning effect, strong selectivity, low residue and no drug hazards, and is suitable for various fruit trees.The preparation method has the advantages of simple process, low energy consumption, no harmful by-products, suitability for large-scale production and promotion, and meeting the needs of green agriculture and pollution-free fruit planting.

A rotigotine-containing patch comprising a support layer and an adhesive layer, wherein the adhesive layer contains at least one selected from the group consisting of rotigotine and pharmaceutically acceptable salts of rotigotine, a rubber-based adhesive base, and an antioxidant, wherein the antioxidant comprises propyl gallate, ascorbyl palmitate, and sodium pyrosulfite.

This invention discloses a method for effectively reducing the cooked flavor of aquatic product compound sauces after heat sterilization, belonging to the field of food processing technology. The method includes: heating the formula with vegetable oil to a suitable temperature, adding capsanthin and one or more fat-soluble antioxidants selected from vitamin E, rosemary extract, and ascorbyl palmitate for pretreatment; adding modified porous starch-based composite material and yeast extract to reconstruct the microenvironment when the sauce cools to below a specified temperature; subsequently performing gradient vacuum degassing; and finally employing a mild, segmented heat sterilization process that uses low-temperature maintenance to activate endogenous enzymes to form a structural barrier, high-temperature instantaneous sterilization to achieve commercial sterility, and rapid cooling to terminate the thermal reaction. This invention inhibits the generation of off-flavor substances during heat sterilization at the reaction mechanism level, while promoting the production of pleasant flavors, significantly reducing the cooked flavor of the product, and improving its umami flavor and textural quality. It is applicable to the production of various aquatic product compound sauces.

The invention relates to the technical field of cosmetics, in particular to an anti-wrinkle brightening composition and a preparation method thereof.The anti-wrinkle brightening composition comprises anti-wrinkle components including hydrolyzed collagen, yeast beta-glucan, methylsilanol hydroxyproline ester aspartate and hydrolyzed sponge; brightening components contained in the whitening mask comprise ascorbyl palmitate phosphate trisodium, hydrolyzed conchiolin protein and hexapeptide-2. The raw materials of the anti-wrinkle component can achieve the anti-wrinkle effect of the composition through different-dimension synchronous effects of promoting collagen synthesis, reducing collagen damage, providing collagen synthesis raw materials and promoting absorption and renewal. The raw materials of the brightening component can regulate and control the upstream of melanin generation, antagonize endothelin-1 mediated melanin, resist oxidation and inhibit tyrosinase activity to achieve a synergistic effect, so that the prepared composition has a brightening effect. Therefore, the composition has the anti-wrinkle and brightening effects, and meets the multi-effect requirements of consumers.

The present invention relates to lipid-modified starches. It provides a process for preparing a lipid-modified starch paste, which includes the steps of combining starch with a lipid component, the lipid component being selected from any one of monoglyceride and ascorbyl palmitate, to provide a suspension, and heat processing the suspension to form the lipid-modified starch paste. The invention also provides a lipid-modified starch paste, which includes a plurality of spherical micro-particles, each spherical micro-particle having a starch core with an amylose-lipid complex layer on an outer surface of the starch core, the amylose-lipid complex layer operable to regulate water absorption capability of the starch core. The invention further extends to provide various uses of a lipid-modified starch paste as a partial or total fat and / or oil replacement in a foodstuff, an improved fat- and / or oil-containing foodstuff and in particular, a low-calorie mayonnaise.

The invention particularly relates to a method for detecting trace sulfur dioxide in food. The invention aims to develop a method for enriching distilled sulfur dioxide in food, which can remove interference ground color in a to-be-detected sample, amplify a to-be-detected signal and realize detection of trace sulfur dioxide in the to-be-detected food. According to the main technical scheme, the method comprises the following steps: acidifying food to be detected, distilling through steam, and introducing distillate into enrichment liquid; after the distillation is finished, rapidly heating the enrichment liquid, and intensively absorbing the released sulfur dioxide gas through the receiving liquid; the enrichment liquid is prepared from the following components: 1.0 mol / L to 2.0 mol / L of triethyl phosphate, 0.1 mol / L to 0.5 mol / L of ascorbyl palmitate and 0.1 mol / L to 0.5 mol / L of Na2HPO4. Through verification, the method can realize detection of trace sulfur dioxide, the detection limit reaches ng level, and the method for detecting part of colored food based on spectral characteristics is expanded.

The invention belongs to the technical field of essence, and particularly discloses a microcapsule embedding preparation method of high-temperature-resistant baking milk-flavored essence, which comprises the following steps: firstly, uniformly mixing milk-flavored essence with ascorbyl palmitate, sucrose fatty acid ester and pullulan; wherein sucrose fatty acid ester, pullulan and ascorbyl palmitate prevent the essence from being oxidized and promote the essence to be compatible with a water-phase wall material to form a stable first mixture; dissolving modified chitosan, starch octenyl succinate and sodium caseinate in water, and adding sodium tripolyphosphate to fully combine all wall material components to construct a compact and high-temperature-resistant wall material matrix, so as to obtain a second mixture; and finally, adding the first mixture into the second mixture, uniformly coating the essence liquid drops, further refining particles through homogenization, compacting the wall material, filtering to remove impurities, and then avoiding essence volatilization and wall material damage through vacuum freeze drying, thereby finally forming the stable high-temperature-resistant milk-flavor essence microcapsule.

This invention relates to pharmaceutical preparations, and more particularly to a composition and its application in the prevention of stretch marks. The composition comprises, by weight, the following ingredients: 5-10 parts of Polygonatum sibiricum, 10-20 parts of Centella asiatica, 5-10 parts of Taxillus chinensis, 1-5 parts of Calendula officinalis, 10-15 parts of polyol, 0.5-1.2 parts of p-hydroxyacetophenone, 20-30 parts of vegetable oil, 1-2 parts of water-in-oil emulsifier, 1-3 parts of hydrogenated lecithin, 0.1-1 part of cetearyl alcohol, 1-2 parts of phytosterol, 0.1-0.5 parts of ascorbyl palmitate, 1-2 parts of hydrolyzed collagen, 1-2 parts of complex vitamins, 0.5-2 parts of schistosome extract, 0.1-0.3 parts of allantoin, 0.1-0.5 parts of sodium hyaluronate, 0.5-3 parts of liquid crystal emulsifier, 0.5-1 part of amino-terminated polyamide amine, 1-2 parts of preservative, and 60-80 parts of water. This invention can effectively stimulate fibroblast proliferation and effectively prevent and lighten the formation of stretch marks.

The invention discloses a synthetic method of ascorbyl palmitate, and relates to the technical field of organic synthesis. The ascorbic acid, the palmitic acid, the N, N-dicyclohexylcarbodiimide and the magnetized modified molecular sieve are subjected to a reaction in the organic solvent, the high-purity ascorbyl palmitate is efficiently prepared, and by-products generated in the reaction process of the catalyst can be efficiently removed. The synthesis method of ascorbyl palmitate provided by the invention is simple in overall process and easy to operate, and the cost is greatly reduced; and the ascorbyl palmitate prepared by the method is high in purity, other raw materials can be more conveniently recycled and reused, and the method is suitable for being popularized and used in the field of synthesis of the ascorbyl palmitate.

This invention discloses a compound natural antioxidant for high-temperature frying and baking of whole grains and its application, belonging to the field of food processing technology. This invention uses oxalic acid, curcumin, and ascorbyl palmitate in a specific ratio, utilizing the synergistic effect between the components. This invention can significantly reduce the formation of harmful substances such as 5-hydroxymethylfurfural, acrylamide, and malondialdehyde in products such as whole grain peach crisps and sachima, effectively inhibiting oil oxidative rancidity. No need to deliberately lower the processing temperature, preserving the original taste and flavor of the product; the compound components are natural, safe, and heat-resistant, suitable for baking and frying conditions, require small amounts, have no unpleasant flavor, meet clean label requirements, are applicable to a wide range of products, and have significantly better antioxidant and harmful inhibitory effects than single antioxidants and ordinary compound formulations, making it suitable for the industrial-scale deep processing and application of whole grain foods.