560results about How to "Restore activity" patented technology

Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.

The invention provides a catalyst used as a titanium-silicate molecular sieve in the process of preparing epoxide from olefin and hydrogen peroxide. The invention is characterized by comprising the following steps: washing with or without a small amount of methanol solvent; purging the catalyst cake with steam directly after reaction; extracting few organic matters absorbed in the catalyst; then stirring in a regenerating kettle and dropwise adding H2O2 with a certain concentration simultaneously; removing the organic matters and low polymers absorbed on the catalyst and in a pore path through oxidative decomposition; and finally, washing with a small amount of methanol or deionized water to remove the organic acid generated by oxidation on the surface of the catalyst. The regenerated catalyst can be circularly used for the epoxidation reaction of olefin to stably maintain the activity of the epoxidation reaction.

The invention relates to an in-situ regeneration method of a butylene oxy-dehydrogenation catalyst, which mainly solves the problems that the in-situ regeneration effect of the butylene oxy-dehydrogenation catalyst is poor, so that the life of the catalyst is shortened, the conversion rate and yield of reaction are reduced, and the change of the catalyst results in long stopping time of a device and influences the output of the device in the prior art. The method comprises the following steps of: a) stopping feeding of oxygen-containing gas and then a butylene raw material, purging the catalyst with 300-500 DEG C superheated water vapor for 0.2-56h, b) gradually reducing the amount of the water vapor till the airspeed of the water vapor is 500-2000h<-1>, filling in air till the molar ratio of the air to the water vapor is 0.05-0.2, controlling the regeneration temperature at 360-450 DEG C, conducting regeneration of the oxy-dehydrogenation catalyst, and c) reducing the amount of the vapor, allowing the temperature rise of a bed to be reduced gradually till the temperature at an inlet and an outlet of the catalyst bed keeps constant, and accomplishing the technical scheme of catalyst regeneration. The method solves the problems better, and can be used for industrial production of preparing butadiene through butylene oxy-dehydrogenation.

The invention discloses a functional nutritional good composition for improving sub-health and a preparation method thereof. Edible and medicinal raw materials such as aloe, licorice root, chrysanthemum flower, green tea, semen cassiae, lotus leaf, fructus crataegi, radix angelicae, white hyacinth bean, lilium brownii, mint, red bean, clove, sword bean and seville orange flower are combined with the modern nutrients such as L-carnitine, methionine, fructo-oligose, fructose, medium chain triglyceride grease powder, protein, vitamins and mineral substances to prepare four types of products. The four types of products are matched with one another in use and can be used for replenishing various nutritional ingredients required by the human body so as to realize the aims of repairing cells, activating the immunity and improving the sub-health.

The invention provides a solid fuel chemical-looping gasification hydrogen production system and method. The solid fuel chemical-looping gasification hydrogen production system is characterized by comprising an air reactor, wherein the air reactor is connected with a first gas-solid separation device; the first gas-solid separation device is connected with a fuel reactor; the fuel reactor is connected with a second gas-solid separation device; a gas outlet of the second gas-solid separation device is connected with a synthetic gas converter; the synthetic gas converter is connected with a CO2 adsorption unit; a discharge port of the CO2 adsorption unit is connected with an H2 processing unit; an outlet of the CO2 adsorption unit is connected with a third gas-solid separation device; a CaCO3 solid outlet of the third gas-solid separation device is connected with a calcining furnace; the calcining furnace is connected with a fourth gas-solid separation device; a gas outlet of the fourth gas-solid separation device is connected with a CO2 processing unit; a solid outlet of the fourth gas-solid separation device is connected with a CaO storage tank; and the CaO storage tank is connected with the CO2 adsorption unit. The system can implement near zero discharge of CO2 in the hydrogen production process, and thus, reduces the influence of greenhouse gas on the environment.

The invention relates to a hydrogenation catalyst regeneration method for a light hydrocarbon noble metal, which comprises the following steps: the hydrocarbon feeding is firstly stopped by using a reactor, heating or heat-exchange equipment, and hydrogen in the hydrogenation process of the light hydrocarbon noble metal; and then the hydrogen is heated by the heating or heat-exchange equipment, so as to enter the reactor to contact an inactivating noble metal catalyst. The catalyst regeneration method is organically combined with a hydrogenation process for the light hydrocarbon, conducts the catalyst regeneration by fully using the conditions in the hydrogenation technology process, and has the advantages of simple process, low cost, short time and good regeneration effect, and can be applied in the regeneration process of hydrogenation catalyst of various light hydrocarbon noble metals.

The invention discloses a denitration catalyst regeneration solution and a preparation method thereof as well as a catalyst regeneration method. The denitration catalyst regeneration solution comprises the following raw material ingredients in parts by weight: 4-6 parts of vanadyl oxalate, 0.08-0.10 part of cerium nitrate, 0.11-0.13 part of lanthanum nitrate, 0.05-0.07 part of copper nitrate, 0.4-0.6 part of silica sol ST-O and 95 parts of deionized water. The catalyst regeneration method comprises the following steps of firstly, evenly mixing vanadyl oxalate and the deionized water; then, feeding cerium nitrate, lanthanum nitrate and copper nitrate into mixed solution, and fully stirring until the mixture is completely dissolved; finally, feeding silica sol ST-O, and continuing to stir until homogeneous phase is obtained; and sequentially carrying out strong scavenging and ultrasonic cleaning on an inactivated denitration catalyst module, soaking the module in cleaning solution for 18-25 minutes, continuing soaking the module in the regeneration solution for 25-40 minutes, taking out the denitration catalyst module and drying. After the denitration catalyst regeneration solution and the catalyst regeneration method are adopted, the activity of the inactivated denitration catalyst can be efficiently recovered, and the temperature range of the catalyst activity is widened.

Anti-SIRPα antibodies, including multi-specific anti-SIRPα antibodies, are provided, as are related compositions and methods. The antibodies of the disclosure bind to SIRPα and can block the interaction of CD47 on one cell with SIRPα on a phagocytic cell. The subject anti-SIRPα antibodies find use in various therapeutic methods. Embodiments of the disclosure include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the anti-SIRPα antibodies; and cell lines that produce the antibodies. Also provided are amino acid sequences of exemplary anti-SIRPα antibodies.

The invention relates to a solid base catalyst for synthesis of glycerol carbonate. The catalyst is composed of 0.66%-28.77% by mass of a base metal oxide and the balance Mg-Al hydrotalcite, with the base metal oxide loaded on the Mg-Al hydrotalcite. Specifically, in the Mg-Al hydrotalcite, Mg and Al are in a mole ratio of 1-5:1. The solid base catalyst provided in the invention has the advantages of good stability, no pollution, and high activity.

The invention provides clear essence containing fullerene polypeptide and relates to the technical field of cosmetics. Essence composition comprises fullerene, a humectant, a sweetening agent, a defoaming agent, a lubricant, a surfactant, polypeptide, a plant extract, a preservative, a bifida ferment lysate, hydroxyphenyl propamidobenzoic acid and ascorbyl palmitate. The essence is rich in fullerene, plant extract and polypeptide, and can strongly resist oxidation and scavenge free radicals. After fullerene is added to the composition and combined with vitamins and polypeptide, active oxygen generated under various conditions can be eliminated, antioxidant duration is long, strong antioxidant effect can still be ensured under the conditions of light and high temperature, and the essence can resist aging, reduce wrinkles and restore skin vitality after use.

The invention provides an environmentally-friendly biomass compound rubber regenerant. The regenerant is prepared from the following raw materials in mass percentage: 60-85% of bio-oil, 10-20% of natural resin and 5-30% of plant polyphenol. The preparation method of the regenerant comprises the following steps: (1) heating the bio-oil to 60-85 DEG C; (2) respectively adding the natural resins andthe plant polyphenol to the bio-oil and evenly mixing; and (3) naturally cooling the evenly mixed product to room temperature to finally obtain the environmentally-friendly biomass compound rubber regenerant product. In the invention, the bio-oil, the natural resins and the plant polyphenol which are extracted from plants are taken as raw materials, and the raw materials are renewable materials, which realizes maximum resource utilization and reduces dependence on petrochemical resource so as to achieve the purpose of green production of reclaimed rubber. The regenerant has the advantages of good rubber regeneration effect, high product quality, low production cost and no pollution and nuisance during the production process. The environmentally-friendly reclaimed rubber produced by the regenerant can be widely applied to various rubber products and can replace rubber materials, thus saving rubber resources.

The invention discloses a processing method and system for inferior crude oil. The method comprises the steps as follows: a, feeding hydrogen-containing gas and the inferior crude oil into a fluidized bed hydrogen absorption zone (I) of a fluidized bed riser reactor for contact with a first catalytic cracking catalyst and a hydrogen adsorption reaction to obtain a hydrogen absorption product; b, feeding the hydrogen absorption product obtained in the step a into a riser cracking zone (II) of the fluidized bed riser reactor for contact with a second catalytic cracking catalyst and a catalytic cracking reaction to obtain catalytic cracked oil-gas. The inferior crude oil processed by the system with the method has the advantages that the conversion rate of the inferior crude oil can be increased substantially, the yield of dry gas and coke is reduced, and accordingly, clean and efficient use of the inferior crude oil is realized.

The invention proposes an up-flow solid carbon source biofilm carrier denitrification bioreactor, comprising a partition plate, a fixed frame, a biofilm carrier, a mechanical stirrer, a heating constant temperature device and the like, wherein the biofilm carrier is a biodegradable polyester sheet modified by thermoplastic starch; and the material is high in mechanical strength and good in biodegradability, benefits for adsorption and biofilm formation of microorganisms, and can be used for providing a carbon source for microbial denitrification. The reactor has the advantages of being concise in structure, simple and convenient to operate, easy for biofilm formation, high in treatment efficiency, strong in DO resistance and pH impact load, low in operation cost, and the like; and the carrier is environment-friendly and free of pollution, and has a high project application value.

The invention discloses a catalyst and a method preparing dimethyl carbonate by using the catalyst. The method comprises two steps: step 1, with urea and aliphatic dihydric alcohol as raw materials, reacting urea with aliphatic dihydric alcohol under the action of the catalyst to synthesize ethylene carbonate or propylene carbonate, wherein reaction conditions are that reaction temperature is 100 to 200 DEG C and 0.5 to 5 mL of nitrogen is introduced into a reaction system per minute; and step 2, subjecting ethylene carbonate or propylene carbonate and methanol to ester interchange so as to synthesize dimethyl carbonate, wherein a reaction condition is that reaction temperature is 60 to 170 DEG C, and the catalyst is a supported catalyst prepared by preparing a solution with a certain concentration from a metal salt or metal oxide and then impregnating a same-volume carrier with the solution. The technical characteristics of the invention are that reaction conditions are mild; reaction is carried out at normal pressure; and the catalyst is easy to separate and recycle, can be repeatedly used and poses no corrosion to equipment and no environmental pollution.

The present invention relates to double-component carried catalyst PdCl2-Cu(OAc)2/zeolite for synthesizing diphenyl carbonate and its preparation. The catalyst consists of zeolite in 50-100 weight portions, PdCl2 in 0.1-10 weight portions and Cu(OAc)2 in 0.1-30 weight protions. It is prepared through equi-volume soaking and roasting at 250-750 deg.c. The catalyst system has also metal acetate as inorganic oxidation-reduction assistant, hydroquinone as organic oxidation-reduction assistant, and tetrabutyl ammonium bride as surfactant. The catalyst has very high catalytic activity and excellent selectivity to liquid phenol in synthesizing diphenyl carbonate. The catalyst is easy to separate from product, easy to recover and regenerate and has simple preparation process.

The invention discloses a regeneration method of an SCR denitration catalyst. The regeneration method includes: (1), performing ash blowing, cleaning and drying on the SCR denitration catalyst which is waste and deactivated; (2), smashing the waste SCR denitration catalyst which is dried well, adding a strong base solution of 10 wt%-40 wt% in mass concentration, and reacting for 3-8 h at temperature of 150-200 DEG C; (3), adjusting pH value of reaction liquid in the step (2) to 9-10, filtering and separating to obtain recovery liquid containing sodium tungstate and sodium vanadate, and adjusting concentration of vanadium in regeneration liquid to 2-10 g/L; (4), soaking the deactivated SCR denitration catalyst dried well in the step (1) in the regeneration liquid with concentration fixed well in the step (3) at room temperature for regeneration, and taking out before placing for 60 min at room temperature; (5), drying, roasting and cooling a catalyst in the step (4) to obtain a regenerated SCR denitration catalyst. The regeneration method has the advantages of good regeneration effect, low SO2/SO3 conversion rate and low regeneration cost.

A multifunctional molecular complex for the transfer of a nucleic acid composition to a target cell is provided. The complex is comprised of A) said nucleic acid composition and B) a transfer moiety comprising 1) one or more cationic polyamines bound to said nucleic acid compositions, 2) one or more endosome membrane disrupting components attached to at least one nitrogen of the polyamine and 3) one or more receptor specific binding components.

The non-hydrocatalyzing adsorption process for desulfurizing hydrocarbon oil in a moving bed reactor includes feeding sulfur containing hydrocarbon oil material and fluidizing medium into the moving bed reactor, contacting alternately with filled sulfur converting agent and sulfur adsorbent, separating the reacted matter flow to obtain product, steam stripping the deactivated sulfur converting agent and sulfur adsorbent and burning to regenerate, and returning the regenerated sulfur converting agent and sulfur adsorbent to the moving bed reactor for circular use. The process completes the catalytic conversion of organic sulfide into inorganic sulfide and the timely adsorption of inorganic sulfide cooperatively inside one reactor, and can realize deep desulfurization of gasoline in non-hydrogenation condition in the desulfurizing rate up to 96 wt%.

The invention discloses belongs to pollution-free laying hen breeding feed, belongs to the field of laying hen feed, and aims to provide the non-harmful, non-residual, and nutrient balanced laying hen breeding feed. The technical scheme adopted is that the pollution-free laying hen breeding feed is matched by the following raw materials in part by weight: 300-350 parts of maize, 80-90 parts of soybean meal, 60-70 parts of bran, 4-6 parts of rock flour, 3-4 parts of hydrogen and calcium, 2-5 parts of methionine, 0.1-1 parts of lysine, 0.1-1 parts of phytase, 5-15 parts of salt, and 1-10 parts of premix. A laying hen fed by adopting the feed has higher qualified rate in tibia length and weight, good chicken uniformity, and high later period egg laying rate.

The invention provides an automatic configuration-updating system of electrogalvanizing solution, comprising a dissolving/configuration system of the electrogalvanizing solution, a filtering system, a vacuum concentration separation system, a circulating system and an electroplating solution collecting tank. Impurities of a filter are taken out regularly by the reasonable and optimized configuration of all the systems; and the diluted electroplating solution is separated into water and the concentrated electroplating solution by the vacuum concentration separation system so as to realize clean production and recover the activity of the electroplating solution, therefore, the electroplating solution can be used circularly without regular updating and waste water discharging, and the environment is effectively protected. The system supplies the electrogalvanizing solution to an electroplating bath and a rinse-system, the electrogalvanizing solution works stably and continuously in the processes of electroplating, filtering, concentration, dissolving and the like, simultaneously, SO4<2-> is relatively stable, and the activity of the solution is easy to be recovered, thus being favorable to the repeated use of the solution and ensuring the stable quality of the electroplating solution.

The invention provides a Co-based catalyst for production of sulfur through reduction of SO2 in flue gas as well as a preparation method and an application of the Co-based catalyst. The catalyst comprises a supporter as well as an active component and an aid which are applied to the supporter, wherein the active component is oxide of Co, and the aid is one or at least two of oxides of Cu, Ni, La, Mg, Ca or Ba. The preparation method comprises the steps as follows: the active component and the aid are supported on the supporter with an equivalent-volume impregnation method, drying, roasting and vulcanization are performed, and the Co-based catalyst is prepared. The Co-based catalyst contains uniformly dispersed component, stable performance and uniform particle size and is applicable to catalysis of SO2 in the flue gas to produce sulfur in a fixed bed reactor.