Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

249 results about "Octanoic Acids" patented technology

Self-repairing high-energy-storage ice-snow-resistant double-layer composite microcapsule suitable for asphalt surface layer and preparation method and application thereof

The invention discloses a self-repairing high-energy-storage ice-snow-resistant double-layer composite microcapsule suitable for an asphalt surface layer and a preparation method and application thereof, and relates to a microcapsule preparation method and application thereof. The invention aims to solve the technical problems of poor core material release and self-healing effects, unstable shell wall material, low heat conductivity, easy leakage and single function of the existing self-repairing microcapsule for the asphalt pavement. The double-layer composite microcapsule is sequentially composed of an inner phase change microcapsule core, an inner phase change microcapsule shell, an outer self-repairing microcapsule core and an outer self-repairing microcapsule shell from inside to outside. Preparing an internal phase change microcapsule core from n-caprylic acid and tetradecane; preparing an internal phase change microcapsule shell by using a carbon nano tube and a double polymer; preparing an external self-repairing microcapsule core from bio-oil and a carbon nanotube; the outer self-repairing microcapsule shell is prepared from the carbon nano tube and the double polymer. Compared with a common asphalt pavement, the healing index of the surface layer of the asphalt pavement prepared from the double-layer composite microcapsule is improved by 8.1%-26.3%. The method can be used in highway fields.
Owner:HARBIN INST OF TECH

Artificial synthesis method for malonyl-coenzyme a (COA) and use thereof

An artificial synthesis method for malonyl-CoA and use thereof are provided. By means of heterologous expression of an aminotransferase and a malonyl-CoA reductase, an artificial synthesis pathway for synthesizing malonyl-CoA by using β-alanine (β-ala) as a precursor is constructed as follows: firstly, under catalysis of a transaminase, β-ala transfers amino groups to α-ketonic acid (such as pyruvic acid, oxaloacetic acid, or α-ketoglutaric acid, etc.), to form an intermediate product 3-oxopropanoate and a corresponding amino acid; the 3-oxopropanoate generates malonyl-CoA under the action of the malonyl-CoA reductase. This pathway addresses the defects of the natural malonyl-CoA synthesis pathway, such as low carbon utilization, consumption of energy substance ATP, release of greenhouse gas CO2, and strict regulation of pathway enzymes, a pyruvate dehydrogenase (PDH) and an acetyl-CoA carboxylase (ACC), thereby achieving high yielding of products using malonyl-CoA as a precursor, including flaviolin, octanoic acid, phloroglucinol, pentadecaheptaene, natamycin, and spinosad.
Owner:SHANGHAI JIAOTONG UNIV

A highly efficient preparation process of octanoylhydroxamic acid

The present application relates to the technical field of fine chemical synthesis, and in particular to an efficient preparation process of octanoyl hydroxamic acid, which comprises the following preparation steps: S1, preparation of ethyl n-octanoate: 90-110 parts by weight of n-octanoic acid and 35-40 parts by weight of ethanol are mixed, and then a solid acid catalyst is added, and the mixture is heated to reflux for reaction for 2.5-3 hours, filtered to obtain a precipitate and a filtrate, and the filtrate is decompressed and distilled to obtain ethyl n-octanoate; S2, preparation of octanoyl hydroxamic acid: 0.4-0.6 parts by weight of sodium acetate and 0.2-0.4 parts by weight of sodium carbonate are added to water, stirred until dissolved, ethanol is added, and after stirring, 24-32 parts by weight of hydroxylamine and ethyl n-octanoate prepared in S1 are added to react to obtain octanoyl hydroxamic acid; the process has the advantage of improving the reusability of the solid acid catalyst.
Owner:YANTAI ORIENTAL CHEM CO LTD +1

Alcohol dehydrogenase and method for preparing (R)-6-hydroxy-8-chloro ethyl caprylate under catalysis of alcohol dehydrogenase

The invention discloses alcohol dehydrogenase and a method for preparing (R)-6-hydroxy-8-chloro ethyl caprylate through catalysis of the alcohol dehydrogenase, and the alcohol dehydrogenase is selected from one or more of mutants of ADH1, ADH2, ADH3, ADH4, ADH5, ADH6, ADH7, ADH8, ADH9, ADH10 and ADH10; the amino acid sequences of the ADH1-ADH10 are as shown in SEQ ID NO. 1 to SEQ ID NO. 10. According to the invention, ethyl 6-carbonyl-8-chloro caprylate can be catalyzed to generate ethyl (R)-6-hydroxy-8-chloro caprylate or ethyl (S)-6-hydroxy-8-chloro caprylate, the reaction conversion rate of the mutant ADH10-A184L / N87F / A61L of ADH10 reaches 99%, and the e.e. Value of the R type is 99.2%.
Owner:杭州微远生物科技有限公司

Soothing smoothie cream containing Centella asiatica extract and preparation method thereof

The present invention relates to the technical field of skin care products, and specifically discloses a soothing smoothie cream containing Centella asiatica extract and a preparation method thereof. The soothing smoothie cream containing Centella asiatica extract includes phase A, phase B, phase C, and phase D, wherein phase A is a compound of solvent, glycerol, butylene glycol, erythritol, allantoin, sodium carbomer, p-hydroxyacetophenone, polypropylene (ester) class / C10-20 alkyl acrylate cross-linked polymer; phase B is a compound of hydrogenated polyisobutene, caprylic / capric triglyceride, and polyglycerol-3 methyl glucose distearate; phase C is arginine; phase D is a compound of 1,2 hexanediol, dipotassium glycyrrhizate, saccharide isomers, Centella asiatica extract, white iris root extract, centella roxburghii extract, and white oak bark extract. The present invention has the advantage of further improving the soothing effect of skin care products.
Owner:广州芭妍化妆品有限公司

Synthesis method of bis-diglycerol polyacyl adipate-2

The invention relates to the technical field of organic synthesis, and particularly discloses a synthesis method of bis-diglycerol polyacyl adipate-2, which comprises the following synthesis steps: S1, stirring and mixing isostearic acid, caprylic capric acid, stearic acid and 12-hydroxystearic acid to obtain total fatty acid; s2, stirring and mixing dipolyglycerol, adipic acid, total fatty acid and an organic tin catalyst, and starting to heat; s3, the initial reaction temperature is controlled to be 140-150 DEG C, the reaction vacuum degree is 0.04 MPa, the heating rate is controlled to be 2-10 DEG C / h in the reaction process, the temperature is increased to 190-210 DEG C, then the reaction vacuum degree is converted into 0.1 MPa, and the heat preservation reaction is conducted for 4-10 h; after the reaction is completed, sampling and measuring an acid value; and S4, after the acid value reaches the standard, carrying out heat preservation reaction for 2-5 hours under a high-vacuum condition, cooling, and filtering to obtain the product. The organic tin catalyst is used, the esterification period is shortened, the conversion rate is increased, and the production cost is reduced.
Owner:SHANGHAI SANKE PAINT & CHEM CO LTD

Synthesis method of absorption enhancer N-(8-[2-hydroxybenzoyl]-amino) sodium caprylate

The invention provides a synthesis method of an absorption enhancer N-(8-[2-hydroxybenzoyl]-amino) sodium caprylate. The method comprises the following steps: dehydrating azelaic acid serving as a raw material to obtain anhydride; the preparation method comprises the following steps: taking 2-aminooctanoic acid as a raw material, reacting with ammonia water to obtain monoamide, concentrating, carrying out Hofmann degradation reaction to obtain an important intermediate 8-aminooctanoic acid, reacting with methyl salicylate in a solvent-free state, and purifying to obtain sodium N-(8-[2-hydroxybenzoyl]-amino) octanoate after the reaction is completed. According to the method, raw materials are easy to obtain, conditions are mild, purification is simple, a high-purity finished product can be obtained, and industrial production is facilitated.
Owner:GUANGDONG YOUYIBO BIOLOGICAL CO LTD

Special low-conductivity cooling liquid for electric vehicle and preparation method of special low-conductivity cooling liquid

The invention discloses a special low-conductivity cooling liquid for an electric vehicle and a preparation method thereof, and the special low-conductivity cooling liquid comprises ethylene glycol, sodium nitrate, octanoic acid, butyl phosphate, benzotriazole, a polyether modified organic silicon defoamer, triethanolamine, imidazole, pigment blue and limonin. The high-temperature-resistant and corrosion-resistant coating is prepared from the following components in percentage by mass: 95 to 100 percent of ethylene glycol, 0 to 0.05 percent of sodium nitrate, 0.2 to 0.4 percent of octanoic acid, 0 to 0.01 percent of butyl phosphate, 0.1 to 0.4 percent of benzotriazole, 0.05 to 0.1 percent of polyether modified organic silicon defoaming agent, 0.5 to 2 percent of triethanolamine, 0 to 0.3 percent of imidazole, 0.02 to 0.06 percent of pigment blue and 0.05 to 0.1 percent of limonin. On the basis of meeting the new national standard of the electric vehicle cooling liquid, the electric vehicle cooling liquid has low conductivity, fire caused by leakage of the cooling liquid can be effectively prevented, and the cooling liquid can effectively provide protection for a new energy electric vehicle system.
Owner:SHANGHAI INST OF TECH +1

Water-based coating agent for candies and preparation method of water-based coating agent

The invention relates to the technical field of food candy coating agents, and particularly discloses a candy water-based coating agent and a preparation method thereof. The invention relates to a water-based coating agent for candies, which comprises the following components in percentage by mass: 15-20% of caprylic capric triglyceride, 10-15% of beeswax, 5-10% of sea buckthron oil, 5-8% of clove oil, 4-7% of mustard seed oil, 3-6% of mono / diglycerol fatty acid ester, 3-6% of stearic acid and the balance of water. The water-based coating agent for the candies not only has a stable emulsification system, but also can be uniformly coated on the surfaces of the candies and quickly dried, so that the production efficiency of the candies is improved, and the production cost is saved.
Owner:GUANGZHOU TIANZIYOU BIOTECHNOLOGY CO LTD

Low-toxicity high-stability cyclic lipid antibacterial peptide and application thereof

The invention discloses a low-toxicity high-stability cyclic lipid antibacterial peptide and application thereof. The antibacterial peptide is prepared by the following steps: firstly, designing an antibacterial peptide template Cn-D '-(M)-DY-cyclo [KXXWZZE], then replacing Cn in the antibacterial peptide template with octanoic acid, decanoic acid and dodecanoic acid, adding Dab or W between Dab and DY, replacing 2 and 3 positive charge amino acids in a ring with arginine or lysine analogues, and replacing 5 and 6 hydrophobic amino acids with DF or DL. Wherein X is equal to R, K, Dab and Orn; z = DW, DF and DL; n is equal to 8, 10 and 12; an in-vitro antibacterial experiment, a hemolysis experiment, a salt ion stability experiment and an enzymolysis stability experiment show that the antibacterial peptide has the advantages of broad-spectrum antibacterial activity, low toxicity and high stability. Induced drug resistance experiments show that the antibacterial peptide has the characteristic that drug resistance is not easy to generate. In-vivo acute toxicity experiments show that the antibacterial peptide has high in-vivo safety and has a good application prospect in preparation of clinical antibacterial drugs.
Owner:LANZHOU UNIV

A method for detecting the content of sodium octanoate in albumin-bound paclitaxel injection

The present invention relates to a method for detecting the content of sodium octanoate in albumin-bound paclitaxel injection, and belongs to the technical field of quality control of albumin-bound paclitaxel injection. The present invention provides a method for detecting the content of sodium octanoate in albumin-bound paclitaxel injection, using high performance liquid chromatography, a chromatographic column with octadecylsilane bonded silica gel as a filler, and a mobile phase consisting of phase A and phase B, wherein mobile phase A is a mixed solution of phosphate buffer solution and acetonitrile, mobile phase B is acetonitrile, and mobile phases A and B are mixed in a certain proportion for gradient elution. The detection method provided by the present invention can quickly and accurately detect the content of sodium octanoate in albumin-bound paclitaxel injection, so as to determine whether the content of sodium octanoate in the imitation preparation is consistent with that of the reference preparation, and whether it meets the requirements of bioequivalence, and has practical promotion and application value.
Owner:SICHUAN HUIYU PHARMA

Antiskid resin type artificial stone material and preparation method thereof

PendingCN120483585AOctanoic AcidsPtru catalyst
The invention discloses an anti-skid resin type artificial stone material which comprises the following raw materials in parts by weight: 10 parts of composite resin, 55-70 parts of modified stone aggregate, 10-25 parts of needle-like wollastonite, 0.4-0.8 part of a curing agent, 0.05-0.2 part of a catalyst and 0.05-0.2 part of a light stabilizer, the composite resin comprises unsaturated polyester resin and an anti-skid filler in a mass ratio of 9: 1-7: 3, and the anti-skid resin type artificial stone material is prepared from the following raw materials in parts by weight: 10 parts of modified stone aggregate, 10-25 parts of needle-like wollastonite, 0.4-0.8 part of a curing agent, 0.05-0.2 part of a catalyst and 0.05-0.2 part of a light stabilizer. The anti-skid filler is one of ethylene glycol acrylate, glyceryl acrylate and acrylic acid modified sorbitol, the modified stone aggregate is formed by modifying stone aggregate through a stone aggregate modifier, and the catalyst is one of cobalt naphthenate, cobalt iso-octoate and manganese iso-octoate. The invention further discloses a preparation method of the anti-skid resin type artificial stone material, optimization balance of the anti-skid performance and other key performance of the artificial stone material is achieved, the application value of the artificial stone material in building decoration can be improved, and the safety and attractiveness of building space can be remarkably improved.
Owner:LIMING VOCATIONAL UNIV

Silicone-oil-free liquid foundation and preparation method thereof

The invention discloses a silicone oil-free liquid foundation and a preparation method thereof, and relates to the technical field of cosmetics, the silicone oil-free liquid foundation comprises the following raw materials by weight: 2-6 parts of an emulsifier, 17-21 parts of grease, 10-14 parts of powder, 3-7 parts of a thickening suspending agent, 44-50 parts of water, 2-6 parts of polyol, 0.8-1.2 parts of an electrolyte, 1-3 parts of a film-forming agent, 0.8-1.2 parts of a preservative, and 2-4 parts of an active component, according to the scheme, a natural grease compounding system such as coconut oil alcohol-octoate / caprate, squalane and simmondsia chinensis seed oil is adopted, through molecular structure bionic design, a breathable moisturizing barrier is constructed while velvet-like smooth touch is provided, the problem that a traditional silicone oil product is sticky, greasy and stuffy is solved, and the requirements of consumers for silicone-oil-free and high-skin-friendliness base makeup are met.
Owner:SUZHOU ANTE COSMETICS CO LTD

Inorganic silicon hybrid polyurethane primer as well as preparation method and application thereof

The invention provides an inorganic silicon hybrid polyurethane primer as well as a preparation method and application thereof, and belongs to the technical field of primer. The primer provided by the invention is prepared from the following raw materials: polyester polyol, polyether polyol, trimethylolpropane, hexamethylene diisocyanate, 3-(phenylamino) propyltrimethoxysilane, ethyl acetate, xylene, an antioxidant, a light stabilizer, stannous octoate and a catalyst. An isocyanate-terminated polyurethane prepolymer is selected as a base material, a silane hybrid structure is introduced, a Si-O-Si network is formed after silane is hydrolyzed, the Si-O-Si network and Ca < 2 + > in concrete form a coordinate bond, and meanwhile, an isocyanate group reacts with water to generate a urea bond to reinforce anchoring. According to the primer disclosed by the invention, through a chemical-physical synergistic effect, the technical problem of bonding failure of a floating dust hardened layer is systematically solved, and an innovative solution is provided for long-acting sealing of a concrete joint.
Owner:XINJIANG AGRI UNIV +1

A process for the hydrogenation reduction of 6-carbonyl-8-chloro octanoic acid ethyl ester to 6-hydroxy-8-chloro octanoic acid ethyl ester

The application discloses a method for preparing 6-hydroxy-8-chlorooctanoic acid ethyl ester by hydrogenation reduction of 6-carbonyl-8-chlorooctanoic acid ethyl ester. The carbonyl group of 6-carbonyl-8-chlorooctanoic acid ethyl ester is reduced to a hydroxyl group through a catalytic hydrogenation reduction reaction under high pressure, so that 6-hydroxy-8-chlorooctanoic acid ethyl ester is obtained. In the reaction process, strong acid, strong base and toxic substances are not involved, the catalyst used can be repeatedly used, the required equipment is not high, the process is simple, the obtained product has high purity and yield, and the method is favorable for large-scale production of enterprises, and provides a new preparation method which is simple and easy to realize, safe and stable, green and environmental protection, low in production cost and high in efficiency, and is suitable for the prior art and actual production.
Owner:TECHNO (FUJIAN) FOOD INGREDIENTS CO LTD

Fructus amomi quality analysis method based on switchable deep eutectic solvent

The invention discloses a fructus amomi quality analysis method based on a switchable deep eutectic solvent. The method specifically comprises the following steps: (1) collecting and crushing fructus amomi samples from different sources; (2) preparing SDES from caprylic acid and tetrabutylammonium bromide, and extracting phenolic compounds in fructus amomi; (3) determining the content of phenolic compounds; (4) digesting the fructus amomi by using SDES, and then determining the content of mineral elements in the fructus amomi; and (5) in combination with a content determination result, performing quality evaluation on the fructus amomi in different areas of Yunnan by adopting multivariate statistical analysis (correlation analysis, clustering analysis and principal component analysis). The method established in the invention has the advantages of rapidness, simplicity, convenience, high extraction efficiency, environmental protection and the like, and a comprehensive fructus amomi quality evaluation system based on SDES can provide certain reference for quality evaluation, quality control and safety analysis of fructus amomi.
Owner:DALI UNIV

Weather-resistant and medium-resistant alkyd resin varnish and preparation method thereof

The invention discloses weather-resistant and medium-resistant alkyd resin varnish and a preparation method thereof. The varnish is prepared from the following raw materials: modified alkyd resin, a composite drier, zirconium iso-octoate with the purity of 12%, an anti-skinning agent, 200 # solvent oil and xylene. The modified alkyd resin is prepared from the following raw materials: soya oil acid, pentaerythritol, benzoic acid, pyrrolidine-2-one-1-acetic acid, dimethylbenzene and a 200 # solvent. According to the invention, pyrrolidine-2-ketone-1-acetic acid is used as a binary acid component to partially or completely replace traditional phthalic anhydride, so that the reaction efficiency of alkyd resin synthesis can be improved, and the problems of yellowing, pulverization and poor water resistance of traditional alkyd resin can be solved; according to the varnish prepared by the invention, on the basis of maintaining the inherent gloss, flexibility and constructability of alkyd resin, the key properties such as weather resistance, water resistance and acid resistance are improved; the whole preparation process of the varnish continues to use mature alkyd resin production equipment and flow, and has good economical efficiency and industrial popularization prospects.
Owner:NORTHWEST YONGXIN PAINT COATINGS CO LTD

MCT formulations for improving cognitive functions

Methods improve cognitive functioning, for example, at least one of episodic memory, executive function, or language skills; supporting memory and / or recall; providing energy and / or ketones to the brain; and / or preventing and / or treating mild cognitive impairment (MCI) in an individual. A composition comprising medium chain triglycerides (MCTs) can be administered to the individual in a daily dosage providing from about 15 g to about 45 g MCTs. The MCTs can include from about 51 wt % to about 90 wt % of octanoic acid. The daily dose can be provided in at least two servings, for example, 2 or 3 servings. Each serving can provide about 15 g MCTs and can include octanoic acid and decanoic acid in a weight ratio of, for example, about 60:about 40. The individual can be 65 years or older and / or have mild cognitive impairment (MCI).
Owner:SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA ET HUMAINES S E C +1

Process to produce low shear strength base oils

A lubricating fluid composition comprising i) a diester of polyethlene glycol esterified with a mixture of octanoic and deconoic acid where the polyethylene glycol may have 2-12 ethylene units and ii)
Owner:VANTAGE SANTOLUBES RES LLC

Oral polypeptide composition

ActiveCN120189496ANervous disorderPeptide/protein ingredientsOctanoic AcidsGastrointestinal absorption
The invention belongs to the field of biological medicine, and particularly relates to an oral polypeptide composition for improving gastrointestinal tract absorption of polypeptide medicine. Specifically disclosed is an oral polypeptide composition comprising polypeptide molecules, medium-chain fatty acids and salts thereof, amino acids, and N-(8-(2-hydroxybenzoyl) amino) caprylic acid (NAC) and salts thereof. The oral polypeptide preparation disclosed by the invention can effectively improve the blood concentration of the polypeptide and improve the bioavailability of the oral polypeptide.
Owner:SHENZHEN AOLI BIOTECHNOLOGY CO LTD

Sodium caprylate as well as preparation method and application thereof

The invention discloses sodium caprylate and a preparation method and application thereof, the sodium caprylate is 8-(2-(2-hydroxyethoxy) benzamido) sodium caprylate, the 8-(2-hydroxybenzamido) sodium caprylate and 2-iodoethanol are subjected to a reaction in an organic solvent containing inorganic base to prepare the sodium caprylate, and the sodium caprylate can be used as a penetration enhancer in an oral administration system. And when the semeglutide oral soluble film is used for preparing the semeglutide oral soluble film, the semeglutide oral soluble film shows a very good in-vitro disintegration effect and a very good permeation promoting effect in animal experiments. The preparation method of the 8-(2-(2-hydroxyethoxy) benzamido) sodium caprylate is simple, does not involve expensive reactants, is convenient for post-treatment, and is beneficial to large-scale production.
Owner:SUZHOU WAYNES BIOTECHNOLOGY CO LTD

Double-layer composite microcapsules suitable for asphalt surface layers with self-repairing, high energy storage and ice and snow resistance, as well as preparation method and application thereof

Double-layer composite microcapsules suitable for asphalt surface layers that are both self-repairing, have high energy storage, and are resistant to ice and snow, as well as their preparation method and application, relate to a microcapsule preparation method and its application. The invention aims to address the technical problems of existing self-repairing microcapsules for asphalt pavements, such as poor core material release and self-healing effects, unstable shell wall materials, low thermal conductivity, easy leakage, and single functionality. The double-layer composite microcapsules of the present invention are composed, from the inside to the outside, of an inner phase-change microcapsule core, an inner phase-change microcapsule shell, an outer self-repairing microcapsule core, and an outer self-repairing microcapsule shell; the inner phase-change microcapsule core is prepared using n-octanoic acid and tetradecane; the inner phase-change microcapsule shell is prepared using carbon nanotubes and a double polymer; the outer self-repairing microcapsule core is prepared using bio-oil and carbon nanotubes; and the outer self-repairing microcapsule shell is prepared using carbon nanotubes and a double polymer. Compared to ordinary asphalt pavement, the healing index of the asphalt pavement surface layer prepared using the double-layer composite microcapsules is increased by 8.1% to 26.3%. It can be used in the highway field.
Owner:HARBIN INST OF TECH

A flavoring of octanoic acid 4-methyl-5-thiazolyl ethyl mercaptan.

PendingCN122355971AOctanoic AcidsThiazole
This invention discloses a compound, octanoic acid 4-methyl-5-thiazole ethyl mercaptan ester, with the specific chemical structure shown below: The aromatic compound is mainly used in food flavorings.
Owner:BEIJING TECH & BUSINESS UNIV

PCI postoperative MACE risk prediction marker for acute ST segment elevation type myocardial infarction patient

The invention discloses a PCI postoperative MACE risk prediction marker for an acute ST segment elevation type myocardial infarction patient, and belongs to the field of biological medicine. The application comprises application of a reagent for detecting the lipid metabolism marker in preparation of a kit for predicting the risk of main adverse cardiovascular events after the PCI operation of a patient suffering from the acute ST segment elevation type myocardial infarction, and the reagent for detecting the lipid metabolism marker comprises glycodeoxycholic acid, [(2R)-3-[(6Z, 9Z, 12Z)-octadeca-6, 9, 10-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, the detection reagent is selected from one or more of a detection reagent for N-((2S, 3R)-1, 3-dihydroxy octadecane-4-alkene-2-yl) acetamide, a detection reagent for 2-(2, 6, 7, 12-trienoyl) oxy-2-[(Z)-octadecane-9-enoyl] oxypropyl] 2-(trimethyl ammonium) ethyl phosphate, 8-hydroxy-8-(3-octyl oxirane-2-yl) octanoic acid and N-((2S, 3R)-1, 3-dihydroxy octadecane-4-alkene-2-yl) acetamide. The four lipid metabolism markers (C44H80NO8P, C18H34O4, C20H39NO3 and C26H43NO5) screened by the invention are used for the prediction efficiency of MACE prediction, the sensitivity of the four lipid metabolism markers reaches 0.889, the specificity of the four lipid metabolism markers is 0.894, the AUC of the four lipid metabolism markers is 0.921, and the four lipid metabolism markers have high sensitivity and high specificity.
Owner:NORTH CHINA PETROLEUM BUREAU GENERAL HOSPITAL

8-tert-butyldiphenylsilyloxy-7-methyl octyl p-toluenesulfonate as well as synthesis method and application thereof

The invention discloses p-toluenesulfonic acid 8-tert-butyl diphenyl silyloxy-7-methyl octyl ester as well as a synthesis method and application thereof, and relates to the technical field of biopesticides. The preparation method comprises the following steps: taking 8-bromocaprylic acid as an initial raw material, and firstly reacting with t-BuOK and 18-crown ether-6; then reacting with pivaloyl chloride to generate acid anhydride, and then carrying out acylation reaction with 4-benzyl oxazolidine-2-ketone; then carrying out diastereoselective methylation; then, NaBH4 reduction is carried out; carrying out hydroxyl protection; then carrying out hydroboration oxidation reaction; and then carrying out TsCl sulfonylation, so as to synthesize the p-toluenesulfonic acid-8-tert-butyl diphenyl silyloxy 7-methyl octyl ester. The optical purity of the (S)-p-toluenesulfonic acid 8-tert-butyl diphenyl silyloxy-7-methyl octyl ester synthesized in the invention reaches 98%, and the optical purity of the (R)-p-toluenesulfonic acid 8-tert-butyl diphenyl silyloxy-7-methyl octyl ester synthesized in the invention also reaches 98%.
Owner:SHANDONG ACADEMY OF AGRICULTURAL SCIENCES

Preparation method of selenium-containing polymer material capable of fixing metal ions

The invention belongs to the field of novel functional polymer materials, and discloses a preparation method of a selenium-containing polymer material capable of fixing metal ions, and the preparation method comprises the following steps: S1, adding PTMEG into a round-bottom reaction flask filled with inert gas, and placing the round-bottom reaction flask in an oil bath pan for melting; s2, MDI, dimethylglyoxime, DSe and anhydrous N, N-dimethylacetamide are sequentially added and fully mixed; s3, stannous octoate and CuCl2 are added at the same time; s4, keeping the temperature of the oil bath pan and continuously reacting; s5, after the reaction is finished, a polymer is precipitated out, and secondary cleaning is conducted through methyl alcohol. The preparation method has the advantages that oximido is introduced into a polyurethane molecular structure to fix metal ions, meanwhile, selenium is introduced in a covalent fixation mode, and through double-site introduction of the metal ions and the selenium, the molecular structure of the polyurethane is greatly improved; the NO catalytic release rate of the material can be regulated and controlled, so that the biocompatibility and applicability of the polymer material in a blood environment are improved, and the application scene is further widened.
Owner:HEZE MEDICAL COLLEGE

Carbon dioxide trapping agent based on organic amine as well as preparation method and application of carbon dioxide trapping agent

The invention discloses a carbon dioxide capturing agent based on organic amine as well as a preparation method and application thereof. The carbon dioxide capturing agent is prepared from the following raw materials in parts by weight: 60 to 80 parts of organic amine, 10 to 20 parts of octanoic acid, 3 to 7 parts of carbon powder, 5 to 10 parts of urea, 10 to 20 parts of polyethylene glycol 400, 1.8 to 4 parts of polyethylene glycol monooleate, 2 to 4.05 parts of choline chloride and 40 to 60 parts of solvent. The absorption performance and regeneration effect of the capture agent on carbon dioxide can be improved.
Owner:XIAMEN ADIT ENVIRONMENTAL PROTECTION TECH CO LTD