240 results about "Decanoic acid" patented technology

The invention relates to the field of coatings, and discloses a biomass-based oil-resistant coating and a preparation method thereof, the coating comprises an additive solution, a paraffin solution and gallic acid; the paraffin solution is obtained by dissolving paraffin in absolute ethyl alcohol; a preparation method of the additive solution comprises the following steps: mixing chitosan powder and an acetic acid aqueous solution to prepare a chitosan solution, ultrasonically dispersing functionalized montmorillonite in deionized water to prepare a suspension, then uniformly mixing the chitosan solution and the suspension, adding modified phytic acid prepared by grafting phytic acid and ethylene glycol diglycidyl ether, and stirring to react; the functional montmorillonite is prepared by modifying modified montmorillonite with titanium dioxide and zinc oxide, then activating the modified montmorillonite with 3-aminopropyltriethoxysilane and succinic anhydride, and then carrying out a ring-opening reaction with glycidyl neodecanoate. The coating prepared by the invention has high water resistance, the Kit oil-proof grade is kept at grade 12, and the oil-proof performance of the coating is greatly improved. Meanwhile, the antibacterial performance, the tensile index and the ultraviolet aging resistance are relatively high.

An oral suspension pharmaceutical composition is disclosed for water soluble salts of arylalkanoic acid (NSAID) drugs such as ibuprofen and naproxen. When mixed with glyceryl esters such as glyceryl caprate / caprylate and water, the resulting combination forms a “liquid scaffold” structure that reliably enables the suspension of significant quantities of said arylalkanoic acid drugs. For example, suspensions containing 25% w / w arylalkanoic acid may be obtained using the aforementioned combination. Suspensions comprising further pharmaceutically active agents, in addition to said arylalkanoic acids, may also be prepared. Also disclosed is a binary blend of glyceryl caprate / caprylate and the sodium salt of ibuprofen and a ternary blend of glyceryl caprate / caprylate and the potassium salt of ibuprofen.

The invention relates to the technical field of cosmetics, in particular to preparation and application of a cyclodextrin-coated azelaic acid oil-control skin-care product. Comprising the following steps: S1, adding deionized water into a mixer, adding a cyclodextrin-azelaic acid inclusion compound, nicotinamide and allantoin, mixing to obtain a water phase, mixing glycerol, caprylic / capric triglyceride, polydimethylsiloxane, polysorbate-80 and tocopheryl acetate to obtain an oil phase, slowly adding the oil phase into the water phase, and shearing and emulsifying to obtain a nanoemulsion; and S2, cooling the nano-emulsion, adding carbomer while stirring, continuously cooling to room temperature, sequentially adding phenoxyethanol, ferulic acid, menthol and essence, adjusting the pH value of the emulsion with triethanolamine, homogenizing, defoaming, disinfecting and filling. By adjusting the proportion of the components in the formula, the skin feeling of the product can be further optimized, so that the product is more comfortable and not greasy, and a lasting oil control effect is provided.

The invention relates to the technical field of organic synthesis, and particularly discloses a synthesis method of bis-diglycerol polyacyl adipate-2, which comprises the following synthesis steps: S1, stirring and mixing isostearic acid, caprylic capric acid, stearic acid and 12-hydroxystearic acid to obtain total fatty acid; s2, stirring and mixing dipolyglycerol, adipic acid, total fatty acid and an organic tin catalyst, and starting to heat; s3, the initial reaction temperature is controlled to be 140-150 DEG C, the reaction vacuum degree is 0.04 MPa, the heating rate is controlled to be 2-10 DEG C / h in the reaction process, the temperature is increased to 190-210 DEG C, then the reaction vacuum degree is converted into 0.1 MPa, and the heat preservation reaction is conducted for 4-10 h; after the reaction is completed, sampling and measuring an acid value; and S4, after the acid value reaches the standard, carrying out heat preservation reaction for 2-5 hours under a high-vacuum condition, cooling, and filtering to obtain the product. The organic tin catalyst is used, the esterification period is shortened, the conversion rate is increased, and the production cost is reduced.

The invention relates to the field of cosmetics, in particular to skin moistening oil containing a water-soluble active matter and a preparation method of the skin moistening oil. The skin moistening oil of the water-soluble active matter is prepared from the following raw materials in parts by mass: 0.1-1 part of a phase A, 3-15 parts of a phase B and 80-100 parts of a phase C, wherein the phase A is a water-soluble component, and the water-soluble component comprises one or more of deionized water, VC ethyl ether and nicotinamide; the phase B is a solvent, and the solvent comprises one or more of ethyoxyl diethylene glycol, 1, 2-pentanediol, isopentanediol and isostearic acid; the phase C is skin moistening oil, and the skin moistening oil comprises caprylic / capric triglyceride. The skin moistening oil product provided by the invention has the advantages of clear and transparent appearance, good fluidity, excellent stability, no need of adding a surfactant or a solubilizer, mildness, no irritation, simple process, controllable cost, good practical value and good application prospect.

A method for preparing a silver powder, comprising: subjecting a first silver salt, a first dispersing agent and a first reducing agent to a first treatment, so as to obtain silver crystal nucleuses; and subjecting the silver crystal nucleus, a second silver salt, a second dispersing agent, a second reducing agent and a modifying agent to a second treatment, so as to obtain a silver powder, wherein the modifying agent comprises lauric acid, decanoic acid and undecanoic acid. The silver powder prepared by means of the method has good dispersity and wettability, a narrow particle size distribution, a small particle size and high sintering activity, and is not prone to agglomeration in a conductive silver paste, thereby enabling the conductive silver paste to have a high solid content and endowing the conductive silver paste with good conductivity. The present invention further relates to a silver powder, a conductive silver paste, an electronic device and electric equipment.

The invention discloses a composition containing achillea millefolium extract, which is prepared from the following ingredients in percentage by weight: 45 to 55 percent of glycerol, 4 to 6 percent of hydrogenated lecithin, 3 to 5 percent of caprylic / capric triglyceride, 1 to 3 percent of 1, 2-hexanediol, 0.8 to 1.2 percent of achillea millefolium extract, 0.4 to 0.6 percent of ergothioneine and the balance of water. Through precise compounding of the achillea millefolium extract and the ergothioneine, the dual effects of anti-inflammation and skin repair are achieved, flavonoid and organic acid components in the achillea millefolium extract can effectively inhibit release of inflammatory mediators such as IL-6 and TNF-alpha, and sensitive symptoms such as red and swollen and pruritus are relieved.

The invention provides a liquid crystal bionic water-locking and oxygen-permeating nursing composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care product is prepared from components in percentage by weight as follows: 20%-40% of glycerin, 5%-10% of hydrogenated lecithin, 5%-10% of phytosterols, 0.1%-0.5% of sodium stearoyl glutamate, 0.01%-0.05% of sodium methyl stearoyl taurate, 0.1%-1% of ceramide NP, 1%-10% of caprylic / capric triglyceride, 1%-10% of squalane, 0.1%-1% of tocopheryl acetate, 0.01%-0.3% of DNA sodium, 0.001%-0.1% of fibronectin and the balance of water. 0.001-0.1% of soluble collagen and the balance of water. The liquid crystal bionic water-locking and oxygen-permeating nursing composition provided by the invention can better form a breathable protective film on the surface of skin, reduce water loss of the skin and help to repair a damaged skin barrier, so that the water-locking and oxygen-permeating nursing effect is achieved.

The invention discloses an oxidoreductase mutant and application thereof, and belongs to the field of enzyme engineering. The invention provides a recombinant oxidoreductase HbKR mutant which is used for catalytically producing (R)-decalactone. The oxidoreductase HbKR mutant disclosed by the invention realizes soluble expression in Escherichia coli BL21 (DE3), and the oxidation activity of the oxidoreductase HbKR mutant is improved by 4.61 times compared with that of a parent enzyme. An oxidoreductase HbKR mutant and lactone hydrolase Rpa3624 derived from Rhodopseudomonas palustris are combined for use, reaction is performed for 0.5 h under the conditions that the temperature is 35 DEG C and the pH value is 10.5, compared with a wild type, the yield of (R)-delta-decalactone is increased to 48.2% from 42.3%, and the stereoselectivity is increased to 98.7% from 94.2%.

A highly efficient method for extracting tea saponin from camellia oleifera seed meal is characterized by comprising the following steps: (1) mixing fatty acid A, fatty acid B, sodium hydroxide, and water to prepare an extractant, wherein fatty acid A is at least one of hexanoic acid, heptanoic acid, octanoic acid, or nonanoic acid, and fatty acid B is decanoic acid; (2) mixing the camellia oleifera seed meal with the extractant prepared in step (1) to extract tea saponin; and (3) after the extraction is completed, adding hydrochloric acid, centrifuging and separating the layers, and collecting the extract at the lower layer. The technical solution provided by the present invention has the following advantages: a high tea saponin extraction rate; the extractant does not contain volatile organic solvents and is easily recyclable and environmentally friendly; the extractant has good reusability and low extraction cost.

The invention discloses breeding of a pichia kluyverovii strain with high yield of beta-lyase and application of the pichia kluyverovii strain in beer fermentation, and belongs to the technical field of bioengineering. The pichia kluyveri B21 is preserved in the China General Microbiological Culture Collection Center, and the preservation number of the pichia kluyveri B21 is CGMCC (China General Microbiological Culture Collection Center) No.34028. The strain can produce high-yield beta-lyase, and the beta-lyase is catalyzed to produce volatile mercaptan and endows beer with fruity flavor. The contents of ethyl acetate, isoamyl acetate, isobutyl acetate, ethyl nonanoate, ethyl caprate, phenethyl acetate, linalool and nerol generated by the pichia kluyveri B21 in a hops simulated culture medium are relatively high, and the volatile substances can increase the fruit fragrance and flower fragrance of beer and enrich the flavor of the beer. The pichia kluyveri B21 is expected to be added into production of other food and beverages so as to enrich flavor substance components.

Methods improve cognitive functioning, for example, at least one of episodic memory, executive function, or language skills; supporting memory and / or recall; providing energy and / or ketones to the brain; and / or preventing and / or treating mild cognitive impairment (MCI) in an individual. A composition comprising medium chain triglycerides (MCTs) can be administered to the individual in a daily dosage providing from about 15 g to about 45 g MCTs. The MCTs can include from about 51 wt % to about 90 wt % of octanoic acid. The daily dose can be provided in at least two servings, for example, 2 or 3 servings. Each serving can provide about 15 g MCTs and can include octanoic acid and decanoic acid in a weight ratio of, for example, about 60:about 40. The individual can be 65 years or older and / or have mild cognitive impairment (MCI).

The invention discloses supramolecular liquid crystal cream and a preparation method thereof, and relates to the technical field of cosmetic preparation. Comprising 0.3%-2% of supramolecular 10-hydroxydecanoic acid-alpha-bisabolol, 1.5%-5% of an emulsifier, 0.5%-3% of behenyl alcohol, 6.8%-23% of an emollient, 1.5%-6% of an emulsion stabilizer, 0.95%-2.85% of a thickener, 5%-14% of a humectant, 0.6%-1.8% of a preservative and a proper amount of water. Wherein the emulsion stabilizer comprises cetostearyl alcohol, and the mass ratio of the cetostearyl alcohol to the behenyl alcohol is (0.5-2): (0.5-3); the thickening agent comprises at least one of xanthan gum, microcrystalline cellulose / cellulose gum and bentonite. The specific thickening agent and the long-chain fatty alcohol emulsion stabilizer are added into the supramolecular system, so that ordered arrangement of liquid crystals in the supramolecular system is remarkably promoted, the mechanical strength of the lamellar liquid crystals is improved, and the stability of the supramolecular liquid crystal system is further improved.

The invention relates to the technical field of neodecanoic acid preparation, and provides a high-purity neodecanoic acid preparation method which comprises the following steps: S1, adding a catalyst into a high-pressure kettle, introducing CO, injecting nonene, and reacting to obtain a reaction solution; s2, mixing the reaction liquid with an extraction agent, feeding the mixture into an extractive distillation tower, and performing extraction and separation to obtain a first organic phase; s3, adding water into the first organic phase, washing and separating to obtain a second organic phase; s4, adding an alkaline additive into the second organic phase, layering to obtain an upper-layer organic phase, and carrying out reduced pressure distillation on the upper-layer organic phase to obtain neodecanoic acid; in the step S1, the raw materials of the catalyst comprise supported cobalt oxide and concentrated sulfuric acid; the supported cobaltous oxide is prepared from the following raw materials: water-soluble cobalt salt and boron nitride; in the step S2, the extraction agent comprises 1, 2-propylene glycol. According to the technical scheme, the problem of low purity of neodecanoic acid in related technologies is solved.

A lubricating fluid composition comprising i) a diester of polyethlene glycol esterified with a mixture of octanoic and deconoic acid where the polyethylene glycol may have 2-12 ethylene units and ii)

Long term storage stable fulvestrant-containing compositions are disclosed. The compositions can include fulvestrant; a solvent selected from dimethyl sulfoxide (DMSO), glycofurol, N-methyl pyrrolidone, and mixtures thereof; an oil mixture selected from a mixture of caprylic and capric triglycerides, a mixture of caprylic, capric and linoleic triglycerides, a mixture of caprylic, capric and succinic triglycerides, and a mixture of propylene glycol dicaprylate and propylene glycol dicaprate; and a sustained release member selected from benzyl benzoate, dihydrolipoic acid, benzyl alcohol and lipoic acid. The fulvestrant-containing compositions have less than about 5% total impurities, on a normalized peak area response (“PAR”) basis as determined by high performance liquid chromatography (“HPLC”) at a wavelength of 223 nm, after at least about 24 months of storage at a temperature of from about 5° C. to about 25° C.

The application discloses a rust-proof enhancer for PAG quenching liquid, and raw materials of the rust-proof enhancer include the following components in parts by weight: 40-45 parts of organic-inorganic rust-proof additive, 35-40 parts of pH regulator, 5-10 parts of non-ferrous metal rust-proof agent and 5-10 parts of antibacterial agent; the organic-inorganic rust-proof additive is a mixture of dicarboxylic acid, tricarboxylic acid, phytic acid, isomeric decanoic acid, fatty acid amide or fatty acid amine salt and sodium tungstate; the components synergistically generate a stable rust-proof film on the surface of metal, the rust-proof film has strong adhesion and can be firmly attached to the surface of metal, is less affected by the polarity of PAG, can effectively enhance the rust-proof performance of steel workpieces after quenching, and has no adverse effect on the properties such as the cloud point, viscosity, foam and cooling characteristics of the quenching liquid.

The application discloses a polyvinyl alcohol composite silicon oxide microcapsule temperature control material and a preparation method thereof, and relates to the technical field of temperature control materials.The emulsion prepared by Pickering emulsification and covered by nanometer silicon oxide and decanoic acid-stearic acid eutectic crystals is mixed with a polyvinyl alcohol solution, and electrostatic spinning treatment is performed, so that a spinning film is obtained, namely the polyvinyl alcohol composite silicon oxide microcapsule temperature control material.The polyvinyl alcohol composite silicon oxide microcapsule temperature control material prepared by the application can provide all-weather radiation refrigeration and phase change energy storage, has excellent recycling performance, and has the characteristics of simple process, stable performance, safe and efficient, low cost, and can be widely applied to the fields of food, medicine and textiles.

A flavor composition is provided. The flavor composition includes decanoic acid; ethyl palmitate; and 10-undecenoic acid.

To provide alternative methods of administration of IL-22, since currently there are limitations for administration of IL-22 for treatment of inflammatory diseases.SOLUTION: Provided is an oral, intra-rectal, or other gut-related pharmaceutical composition comprising an IL- 22 protein and an absorption enhancer selected from the group consisting of N(8-[2- hydroxybenzoyl]aino)caprylic acid (NAC), N-(10-[2-hydroxybenzoyl]amino)decanoic acid (NAD), a salt of the NAC or the NAD.SELECTED DRAWING: Figure 1

The application provides a method for separating and purifying 3-hydroxydecanoic acid from Pseudomonas bacteria. First, the fermentation product of Pseudomonas bacteria is decomposed by alkali to obtain monomers of 3-hydroxydecanoic acid. Then, activated carbon is used for decolorization, and microfiltration membrane and ultrafiltration membrane are used for treatment to remove macromolecular impurities. Finally, a sodium 3-hydroxydecanoate solution is loaded onto a polystyrene-divinylbenzene macroporous resin column modified by polyethyleneimine, and eluted with an ethanol-water (volume ratio 1:1) solution with a pH of 11. The eluate is collected, ethanol is evaporated, a purified sodium 3-hydroxydecanoate solution is obtained, hydrochloric acid is added to adjust the pH to 3-4, and the precipitate is collected by centrifugation and dried to obtain a 3-hydroxydecanoic acid product. The content of 3-hydroxydecanoic acid is detected by liquid chromatography, and the total content of 3-hydroxydecanoic acid in the purified product is higher than 90%. The method uses less organic solvent, the steps are simple, the purity of the obtained product is high, and the application requirements of cosmetics and pharmaceutical intermediates are met.

The invention relates to the field of lipidosome technology and skin external preparations, in particular to bionic ceramide coated retinol lipidosome and a preparation method and application of the bionic ceramide coated retinol lipidosome. The liposome is prepared from the following raw materials in parts by weight: 1.0 to 3.0 weight percent of ceramide NP, 1.0 to 3.0 weight percent of ceramide AP, 0.05 to 0.5 weight percent of ceramide EOP, 1.0 to 3.0 weight percent of cholesterol, 0.50 to 2.0 weight percent of meadowfoam seed oil, 3.0 to 10.0 weight percent of hydrogenated lecithin, 1.0 to 3.0 weight percent of retinol, 0.50 to 2.50 weight percent of tocopheryl acetate, 15.0 to 45.0 weight percent of caprylic / capric triglyceride MCT, 1.0 to 5.0 weight percent of propylene glycol, 15.0 to 45.0 weight percent of glycerol and the balance of water, the bionic layered film is constructed by the multi-subtype ceramide, cholesterol and hydrogenated lecithin, the oil phase and an antioxidant system are cooperated, the stability of retinol under light, heat and oxygen is remarkably improved, slow release is achieved, meanwhile, skin tolerance is improved, and the bionic layered film can be widely applied to essence, emulsion, face cream, ampoule and other external skin care preparations.

A pharmaceutical composition is provided. The pharmaceutical composition includes dexamethasone at a concentration of at least 400 picomolar and up to 20 millimolar and decanoic acid at a concentration of at least 10 micromolar and up to 5 millimolar. In some embodiments, the pharmaceutical composition is used to treat osteoarthritis.

The invention discloses expanded vermiculite-based decanoic acid and stearic acid composite phase change aggregate as well as a preparation method and application thereof, and belongs to the technical field of building materials. The expanded vermiculite-based decanoic acid and stearic acid composite phase change aggregate is expanded vermiculite which is compositely packaged by silica gel / epoxy resin and adsorbs a binary phase change material; wherein the silica gel / epoxy resin composite packaging is that silica gel is firstly used for packaging, and then epoxy resin is used for packaging; the binary phase change material is obtained by mixing capric acid and stearic acid according to a mass ratio of (9: 1)-(8.5: 1.5); the mass of the binary phase change material does not exceed 40% of the total mass of the expanded vermiculite and the binary phase change material. According to the invention, decanoic acid and stearic acid are selected as binary phase change materials, expanded vermiculite is taken as an adsorption material, then silica gel / epoxy resin is utilized to carry out surface packaging and hardening treatment on a phase change polymer to prepare phase change aggregate, the phase change aggregate is applied to the phase change concrete, and the obtained phase change concrete can effectively buffer temperature change and reduce temperature fluctuation; the indoor temperature is kept stable, the indoor comfort is improved, and the air conditioner adjusting frequency is reduced.

The invention provides an extraction process of a dunaliella salina fat-soluble anti-allergy active matter based on a caprylic acid-4-terpineol hydrophobic deep eutectic solvent, and belongs to the technical field of natural product extraction. The extraction process comprises the following steps: S1, adding dunaliella salina into a jasmine flower solution according to a ratio of 1: 20 (W / V), stirring and dispersing, and then centrifuging to obtain a wet substance; s2, octanoic acid, capric acid and 4-terpineol are mixed to prepare a hydrophobic deep eutectic solvent; s3, dispersing the wet substance in water to serve as algae liquid, adding a hydrophobic deep eutectic solvent, extracting for 30 minutes at the temperature of 80-100 DEG C, and centrifuging to take an upper oil phase; and S4, dissolving the oil phase in caprylic / capric triglyceride according to a ratio of 1-10% (W / W) to obtain the anti-allergy active matter. The extraction process is simple, the extracted active matter has good anti-allergy and anti-oxidation effects and safety, the fishy smell of dunaliella salina is effectively removed, and the active matter can be directly applied to cosmetics and other products.

Nanoemulsion composition for the treatment of inflammatory bowel diseases, comprising: a) 1.0% (w / w) curcumin as active pharmaceutical ingredient; b) 10.0% w / w Caprylic / Capric triglycerides as oil phase; c) 15.0% w / w Tween 80 as surfactant; d) 10.0% w / w PEG 400 as co-surfactant; e) 2.0% w / w lecithin as emulsifier; f) 2.0% w / w ethanol as a solubilizer; and g) distilled water qs to 100 w / w, h) wherein the composition forms a nanoemulsion having a mean particle size in the range of 90-120 nm and a polydispersity index of less than 0.3 and provides sustained curcumin release for at least 12 hours in simulated intestinal fluid.

The invention discloses a method for preparing whole bio-based 2-nonanol by taking rhamnose waste liquid as a raw material, which comprises the following steps: taking the rhamnose waste liquid containing 3-hydroxydecanoic acid dimer and 3-hydroxydecanoic acid generated in the rhamnose production process as the raw material, taking water as a solvent, and reacting under the action of a catalyst and an additive under illumination to obtain the whole bio-based 2-nonanol. And reacting to obtain the whole bio-based 2-nonanol. The invention aims to prepare the whole bio-based 2-nonanol from the rhamnose waste liquid, on one hand, the oil phase waste liquid in the rhamnose production process can be recycled, the treatment cost of three wastes is reduced, and the added value of the product is increased, and on the other hand, the invention provides a novel method for preparing the whole bio-based 2-nonanol. The obtained whole bio-based 2-nonanol product better meets the requirements of people on safe, green and natural products at present.

The invention provides antimicrobial composition comprising (a) a first active ingredient, wherein in the first active ingredient is selected from the group consisting of petroleum jelly, EpiCeram® emulsion, and / or glycerin, and (b) a second active ingredient selected from the group consisting of 1-octanoyl-rac-glycerol, 1-decanoyl-rac-glycerol, glycerol monolaurate (GML), rac-glycerol 1-myrstate, glycerol monocaprate, glycerol monocaprylate, glycerol monomyristate, or reutericyclin, wherein the second active ingredient is present at a concentration of 10 μg / ml to 100 mg / ml in the composition. The compositions are useful as antimicrobial agents.

This invention relates to the treatment of glucose transporter type 1 deficiency syndrome (Glut1-DS). In particular, the invention relates to specific medium-chain triglyceride compositions, enriched for C10 (decanoic acid), for use in treating movement disorders in Glut1-DS patients.