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281 results about "Decanoic acid" patented technology

Decanoic acid, also known as capric acid (C10:0) or decylic acid, is a saturated fatty acid. Its formula is CH₃(CH₂)₈COOH. Salts and esters of decanoic acid are called decanoates or caprates. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats.

Biomass-based oil-resistant coating and preparation method thereof

The invention relates to the field of coatings, and discloses a biomass-based oil-resistant coating and a preparation method thereof, the coating comprises an additive solution, a paraffin solution and gallic acid; the paraffin solution is obtained by dissolving paraffin in absolute ethyl alcohol; a preparation method of the additive solution comprises the following steps: mixing chitosan powder and an acetic acid aqueous solution to prepare a chitosan solution, ultrasonically dispersing functionalized montmorillonite in deionized water to prepare a suspension, then uniformly mixing the chitosan solution and the suspension, adding modified phytic acid prepared by grafting phytic acid and ethylene glycol diglycidyl ether, and stirring to react; the functional montmorillonite is prepared by modifying modified montmorillonite with titanium dioxide and zinc oxide, then activating the modified montmorillonite with 3-aminopropyltriethoxysilane and succinic anhydride, and then carrying out a ring-opening reaction with glycidyl neodecanoate. The coating prepared by the invention has high water resistance, the Kit oil-proof grade is kept at grade 12, and the oil-proof performance of the coating is greatly improved. Meanwhile, the antibacterial performance, the tensile index and the ultraviolet aging resistance are relatively high.
Owner:GUANGDONG BOHAI CHEM TECH CO LTD

Lipophilic Drug Suspensions

An oral suspension pharmaceutical composition is disclosed for water soluble salts of arylalkanoic acid (NSAID) drugs such as ibuprofen and naproxen. When mixed with glyceryl esters such as glyceryl caprate / caprylate and water, the resulting combination forms a “liquid scaffold” structure that reliably enables the suspension of significant quantities of said arylalkanoic acid drugs. For example, suspensions containing 25% w / w arylalkanoic acid may be obtained using the aforementioned combination. Suspensions comprising further pharmaceutically active agents, in addition to said arylalkanoic acids, may also be prepared. Also disclosed is a binary blend of glyceryl caprate / caprylate and the sodium salt of ibuprofen and a ternary blend of glyceryl caprate / caprylate and the potassium salt of ibuprofen.
Owner:IBUMIX LTD

Soothing smoothie cream containing Centella asiatica extract and preparation method thereof

The present invention relates to the technical field of skin care products, and specifically discloses a soothing smoothie cream containing Centella asiatica extract and a preparation method thereof. The soothing smoothie cream containing Centella asiatica extract includes phase A, phase B, phase C, and phase D, wherein phase A is a compound of solvent, glycerol, butylene glycol, erythritol, allantoin, sodium carbomer, p-hydroxyacetophenone, polypropylene (ester) class / C10-20 alkyl acrylate cross-linked polymer; phase B is a compound of hydrogenated polyisobutene, caprylic / capric triglyceride, and polyglycerol-3 methyl glucose distearate; phase C is arginine; phase D is a compound of 1,2 hexanediol, dipotassium glycyrrhizate, saccharide isomers, Centella asiatica extract, white iris root extract, centella roxburghii extract, and white oak bark extract. The present invention has the advantage of further improving the soothing effect of skin care products.
Owner:广州芭妍化妆品有限公司

Preparation and application of cyclodextrin-coated azelaic acid oil-control skin-care product

The invention relates to the technical field of cosmetics, in particular to preparation and application of a cyclodextrin-coated azelaic acid oil-control skin-care product. Comprising the following steps: S1, adding deionized water into a mixer, adding a cyclodextrin-azelaic acid inclusion compound, nicotinamide and allantoin, mixing to obtain a water phase, mixing glycerol, caprylic / capric triglyceride, polydimethylsiloxane, polysorbate-80 and tocopheryl acetate to obtain an oil phase, slowly adding the oil phase into the water phase, and shearing and emulsifying to obtain a nanoemulsion; and S2, cooling the nano-emulsion, adding carbomer while stirring, continuously cooling to room temperature, sequentially adding phenoxyethanol, ferulic acid, menthol and essence, adjusting the pH value of the emulsion with triethanolamine, homogenizing, defoaming, disinfecting and filling. By adjusting the proportion of the components in the formula, the skin feeling of the product can be further optimized, so that the product is more comfortable and not greasy, and a lasting oil control effect is provided.
Owner:GUANGZHOU SENYE BIOMEDICAL TECH CO LTD

Capric acid-myristyl alcohol phase change material as well as preparation method and application thereof

PendingCN119505819Areduce leakageWide phase transition temperature rangeHeat-exchange elementsGraphiteHollow core
The invention discloses a decanoic acid-myristyl alcohol phase change material as well as a preparation method and application thereof, and belongs to the technical field of energy storage phase change materials. The preparation method comprises the following steps: firstly, mixing capric acid and myristyl alcohol, carrying out heat treatment to prepare a binary eutectic mixture, then adsorbing the obtained binary eutectic mixture into hollow open steel balls through an impregnation method, cooling, drying, and finally packaging to obtain the hollow open steel balls. The phase-change temperature range of the prepared composite phase-change material is 18.30-20.86 DEG C. Compared with the phase-change temperature of a traditional phase-change material, the phase-change temperature range suitable for organic matters is effectively widened, good thermal characteristics of a single component are kept, the composite phase-change material better conforms to the working environment of an underground energy structure, and the working efficiency is improved. Meanwhile, the graphite powder is doped, so that a plurality of heat conduction channels are formed in the phase-change concrete, and the heat exchange capacity of the phase-change concrete is effectively improved.
Owner:CHONGQING UNIV

Ceramide liposome and application thereof

The invention relates to the field of cosmetics, and discloses ceramide liposome and application thereof.The ceramide liposome is prepared from, by mass, 1.5-3 parts of ceramide NP, 1-3 parts of octyldodecanol, 0.5-2 parts of caprylic / capric triglyceride, 11-18 parts of hydrogenated lecithin, 2-6 parts of sucrose stearate, 3-7 parts of polyglycerol-10 oleate and 25-35 parts of glycerinum, and the balance is water. 0.5-8 parts of 1, 2-pentanediol, and the balance of water. The ceramide liposome provided by the invention has good stability at least at 40 DEG C, is not easy to cause lactic acid pricking pain and allergy after being smeared on skin, and can be used for sensitive skin; the skin care product can reduce skin transdermal moisture loss, maintain skin cutin moisture, reduce skin heme content, improve skin gloss, relieve skin dryness, relieve skin redness and improve skin fineness, and has the effects of moisturizing, repairing and relieving.
Owner:YOUYAN BIOTECHNOLOGY (HUZHOU) CO LTD

Synthesis method of bis-diglycerol polyacyl adipate-2

The invention relates to the technical field of organic synthesis, and particularly discloses a synthesis method of bis-diglycerol polyacyl adipate-2, which comprises the following synthesis steps: S1, stirring and mixing isostearic acid, caprylic capric acid, stearic acid and 12-hydroxystearic acid to obtain total fatty acid; s2, stirring and mixing dipolyglycerol, adipic acid, total fatty acid and an organic tin catalyst, and starting to heat; s3, the initial reaction temperature is controlled to be 140-150 DEG C, the reaction vacuum degree is 0.04 MPa, the heating rate is controlled to be 2-10 DEG C / h in the reaction process, the temperature is increased to 190-210 DEG C, then the reaction vacuum degree is converted into 0.1 MPa, and the heat preservation reaction is conducted for 4-10 h; after the reaction is completed, sampling and measuring an acid value; and S4, after the acid value reaches the standard, carrying out heat preservation reaction for 2-5 hours under a high-vacuum condition, cooling, and filtering to obtain the product. The organic tin catalyst is used, the esterification period is shortened, the conversion rate is increased, and the production cost is reduced.
Owner:SHANGHAI SANKE PAINT & CHEM CO LTD

Lipid nanoparticle composition comprising sodium DNA

The present invention relates to a lipid nanoparticle composition comprising sodium DNA, and more particularly, to a lipid nanoparticle composition comprising: sodium DNA as an active ingredient; the sodium bis (lauramide glutamine) lysine is used as an amphiphilic surfactant; the distearoyl phosphatidylcholine is used as an auxiliary surfactant; cholesterol as a stabilizer; the auxiliary stabilizer is selected from the group consisting of PEG-120 stearate, polyglycerol-4 decanoate, a poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer (PEG-PCL copolymer) and a mixture of the PEG-120 stearate, the polyglycerol-4 decanoate and the poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer; and a solvent.
Owner:H&A PHARMACHEM CO LTD

Transparent hydrophobic paper as well as preparation method and application thereof

The invention belongs to the technical field of hydrophobic materials, and particularly relates to transparent hydrophobic paper and a preparation method and application thereof.The preparation method comprises the steps that a reaction reagent n-decanoic acid is mixed with a catalyst, a condensing agent and an organic solvent to obtain a reaction solution, the catalyst is 4-dimethylaminopyridine, and the condensing agent is 4-dimethylaminopyridine; the condensing agent is 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride, and the solvent is a solvent; the transparent paper-based material is placed in a reaction solution to be subjected to esterification reaction, and the transparency of the transparent paper-based material is hardly influenced; the esterification reaction introduces a hydrophobic alkyl chain on the surface of the paper-based material, so that the hydrophobicity of the paper-based material is improved, the transparency of the paper-based material can be retained, and the film-forming property of PEDOT: PSS on a paper base is not influenced.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES)

Skin moistening oil containing water-soluble active matters and preparation method of skin moistening oil

PendingCN121971321AmildImprove the pleasure of useCosmetic preparationsToilet preparationsPolymer scienceActive agent
The invention relates to the field of cosmetics, in particular to skin moistening oil containing a water-soluble active matter and a preparation method of the skin moistening oil. The skin moistening oil of the water-soluble active matter is prepared from the following raw materials in parts by mass: 0.1-1 part of a phase A, 3-15 parts of a phase B and 80-100 parts of a phase C, wherein the phase A is a water-soluble component, and the water-soluble component comprises one or more of deionized water, VC ethyl ether and nicotinamide; the phase B is a solvent, and the solvent comprises one or more of ethyoxyl diethylene glycol, 1, 2-pentanediol, isopentanediol and isostearic acid; the phase C is skin moistening oil, and the skin moistening oil comprises caprylic / capric triglyceride. The skin moistening oil product provided by the invention has the advantages of clear and transparent appearance, good fluidity, excellent stability, no need of adding a surfactant or a solubilizer, mildness, no irritation, simple process, controllable cost, good practical value and good application prospect.
Owner:SHANGHAI ZHONGYI DAILY CHEM CO LTD +1

Silver powder and preparation method therefor, conductive silver paste, electronic device and electric equipment

A method for preparing a silver powder, comprising: subjecting a first silver salt, a first dispersing agent and a first reducing agent to a first treatment, so as to obtain silver crystal nucleuses; and subjecting the silver crystal nucleus, a second silver salt, a second dispersing agent, a second reducing agent and a modifying agent to a second treatment, so as to obtain a silver powder, wherein the modifying agent comprises lauric acid, decanoic acid and undecanoic acid. The silver powder prepared by means of the method has good dispersity and wettability, a narrow particle size distribution, a small particle size and high sintering activity, and is not prone to agglomeration in a conductive silver paste, thereby enabling the conductive silver paste to have a high solid content and endowing the conductive silver paste with good conductivity. The present invention further relates to a silver powder, a conductive silver paste, an electronic device and electric equipment.
Owner:BYD CO LTD

Rhamnolipid composition, daily chemical and application

The invention relates to the technical field of daily chemicals, and provides a rhamnolipid composition, a daily chemical and application. The rhamnolipid composition comprises rhamnolipid and 3-hydroxydecanoic acid, and the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is (1: 999999) to (1: 8). Compared with a rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid to rhamnolipid is higher, the rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid to rhamnolipid meets the requirement disclosed by the invention is added into the daily chemicals, so that the irritation can be reduced, and the thickening difficulty of the daily chemicals needing to be thickened can be reduced.
Owner:WANHUA CHEM GRP CO LTD

Composition containing achillea millefolium extract and application of composition in preparation of products with anti-inflammatory and / or skin repairing effects

The invention discloses a composition containing achillea millefolium extract, which is prepared from the following ingredients in percentage by weight: 45 to 55 percent of glycerol, 4 to 6 percent of hydrogenated lecithin, 3 to 5 percent of caprylic / capric triglyceride, 1 to 3 percent of 1, 2-hexanediol, 0.8 to 1.2 percent of achillea millefolium extract, 0.4 to 0.6 percent of ergothioneine and the balance of water. Through precise compounding of the achillea millefolium extract and the ergothioneine, the dual effects of anti-inflammation and skin repair are achieved, flavonoid and organic acid components in the achillea millefolium extract can effectively inhibit release of inflammatory mediators such as IL-6 and TNF-alpha, and sensitive symptoms such as red and swollen and pruritus are relieved.
Owner:GUANGZHOU XIE XIE BIOTECHNOLOGY CO LTD

Water-soluble squalane nanoemulsion composition as well as preparation method and application thereof

The invention belongs to the technical field of cosmetics, and particularly relates to a water-soluble squalane nanoemulsion composition as well as a preparation method and application thereof. The water-soluble squalane nano-emulsion composition provided by the invention is prepared from the following components in percentage by mass: 5 to 60 weight percent of squalane, 4 to 20 weight percent of an emulsifying agent, 2 to 8 weight percent of a preservative, 10 to 60 weight percent of water, 10 to 40 weight percent of a penetration enhancer and 0.1 to 0.5 weight percent of a stabilizing agent, the emulsifier comprises at least three of sodium stearoyl glutamate, polyglycerol-10 myristate, hydrogenated lecithin and caprylic / capric triglyceride. According to the water-soluble squalane nano-emulsion composition, the system stability is greatly improved, the particle size can be basically kept unchanged at 4 DEG C, 25 DEG C and 50 DEG C, the phenomena of layering, demulsification and the like are avoided, and the loss of the squalane content in the water-soluble squalane nano-emulsion composition is small.
Owner:EFFEPHARM (SHANGHAI) CO LTD

Temperature-responsive emamectin benzoate-nitenpyram co-delivery liposome nano-pesticide and preparation method thereof

The invention discloses a temperature response type emamectin benzoate-nitenpyram co-delivery liposome nano pesticide and a preparation method thereof. The compound emamectin benzoate and nitenpyram tablet is prepared from the following raw materials: 10%-40% of emamectin benzoate, 10%-40% of nitenpyram, 15%-50% of hydrogenated lecithin, 2%-35% of cholesterol and 1%-25% of a temperature-sensitive material, and the temperature-sensitive material is a decanoic acid-stearic acid binary fatty acid eutectic mixture. Compared with a conventional preparation, the temperature response type emamectin benzoate-nitenpyram co-delivery liposome nano pesticide provided by the invention shows excellent leaf surface wettability and lower toxicity to zebra fish. Indoor biological activity experiments show that the control effect of the nano-pesticide on the plutella xylostella is improved along with temperature rise and is consistent with the population growth trend of the plutella xylostella, and emamectin benzoate and nitenpyram in the nano-pesticide have a synergistic effect in the control of the plutella xylostella.
Owner:INSTITUTE OF ENVIRONMENT AND SUSTAINABLE DEVELOPMENT IN AGRICULTURE CAAS

A kind of synthesis method of ascorbyl tetraisopalmitate

The invention relates to the field of chemical synthesis, and specifically discloses a method for synthesizing ascorbic acid tetraisopalmitate. The method is a one-step synthesis, comprising: mixing an alkaline substance, a condensing agent and vitamin C with 2-hexyldecanoic acid in an organic solvent, and performing an esterification reaction to obtain ascorbic acid tetraisopalmitate. The synthesis method avoids the generation of by-products such as ascorbic acid palmitate (CAS No.: 137-66-6) and ascorbic acid dipalmitate (CAS No.: 28474-90-0), and avoids the use of a strong corrosive agent thionyl chloride, thereby extending the service life of equipment and reducing the pressure of daily maintenance and inspection of equipment. The reaction conditions are mild, the reaction process is controllable, the product is easy to separate and purify, the yield is high, the purity is high, and the method is suitable for industrial-scale production.
Owner:ZHUHAI BIRUI MEDICAL TECH CO LTD

Liquid crystal bionic water-locking and oxygen-permeating nursing composition as well as preparation method and application thereof

The invention provides a liquid crystal bionic water-locking and oxygen-permeating nursing composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care product is prepared from components in percentage by weight as follows: 20%-40% of glycerin, 5%-10% of hydrogenated lecithin, 5%-10% of phytosterols, 0.1%-0.5% of sodium stearoyl glutamate, 0.01%-0.05% of sodium methyl stearoyl taurate, 0.1%-1% of ceramide NP, 1%-10% of caprylic / capric triglyceride, 1%-10% of squalane, 0.1%-1% of tocopheryl acetate, 0.01%-0.3% of DNA sodium, 0.001%-0.1% of fibronectin and the balance of water. 0.001-0.1% of soluble collagen and the balance of water. The liquid crystal bionic water-locking and oxygen-permeating nursing composition provided by the invention can better form a breathable protective film on the surface of skin, reduce water loss of the skin and help to repair a damaged skin barrier, so that the water-locking and oxygen-permeating nursing effect is achieved.
Owner:GUANGDONG ZAIMETIAN BIOTECHNOLOGY CO LTD

Oxidoreductase mutant and application thereof

The invention discloses an oxidoreductase mutant and application thereof, and belongs to the field of enzyme engineering. The invention provides a recombinant oxidoreductase HbKR mutant which is used for catalytically producing (R)-decalactone. The oxidoreductase HbKR mutant disclosed by the invention realizes soluble expression in Escherichia coli BL21 (DE3), and the oxidation activity of the oxidoreductase HbKR mutant is improved by 4.61 times compared with that of a parent enzyme. An oxidoreductase HbKR mutant and lactone hydrolase Rpa3624 derived from Rhodopseudomonas palustris are combined for use, reaction is performed for 0.5 h under the conditions that the temperature is 35 DEG C and the pH value is 10.5, compared with a wild type, the yield of (R)-delta-decalactone is increased to 48.2% from 42.3%, and the stereoselectivity is increased to 98.7% from 94.2%.
Owner:JIANGNAN UNIV

Abiraterone decanoate prodrugs and use in therapy

Sustained-release abiraterone prodrug formulations, methods, and kits for parenteral administration to a human subject having a sex hormone-dependent or androgen receptor driven disease or disorder, such as a sex hormone-dependent benign or malignant disorder such as prostate cancer, an androgen receptor driven cancer, and / or a syndrome due to androgen excess.
Owner:ASTELLAS US LLC

A method for efficiently extracting tea saponin from camellia seed meal

A highly efficient method for extracting tea saponin from camellia oleifera seed meal is characterized by comprising the following steps: (1) mixing fatty acid A, fatty acid B, sodium hydroxide, and water to prepare an extractant, wherein fatty acid A is at least one of hexanoic acid, heptanoic acid, octanoic acid, or nonanoic acid, and fatty acid B is decanoic acid; (2) mixing the camellia oleifera seed meal with the extractant prepared in step (1) to extract tea saponin; and (3) after the extraction is completed, adding hydrochloric acid, centrifuging and separating the layers, and collecting the extract at the lower layer. The technical solution provided by the present invention has the following advantages: a high tea saponin extraction rate; the extractant does not contain volatile organic solvents and is easily recyclable and environmentally friendly; the extractant has good reusability and low extraction cost.
Owner:SHAOYANG UNIV

Breeding of pichia kluyveri strain with high yield of beta-lyase and application of pichia kluyveri strain in beer fermentation

InactiveCN121160491AFungiMicroorganism based processesPhenethyl acetateLyase
The invention discloses breeding of a pichia kluyverovii strain with high yield of beta-lyase and application of the pichia kluyverovii strain in beer fermentation, and belongs to the technical field of bioengineering. The pichia kluyveri B21 is preserved in the China General Microbiological Culture Collection Center, and the preservation number of the pichia kluyveri B21 is CGMCC (China General Microbiological Culture Collection Center) No.34028. The strain can produce high-yield beta-lyase, and the beta-lyase is catalyzed to produce volatile mercaptan and endows beer with fruity flavor. The contents of ethyl acetate, isoamyl acetate, isobutyl acetate, ethyl nonanoate, ethyl caprate, phenethyl acetate, linalool and nerol generated by the pichia kluyveri B21 in a hops simulated culture medium are relatively high, and the volatile substances can increase the fruit fragrance and flower fragrance of beer and enrich the flavor of the beer. The pichia kluyveri B21 is expected to be added into production of other food and beverages so as to enrich flavor substance components.
Owner:JIANGNAN UNIV

MCT formulations for improving cognitive functions

Methods improve cognitive functioning, for example, at least one of episodic memory, executive function, or language skills; supporting memory and / or recall; providing energy and / or ketones to the brain; and / or preventing and / or treating mild cognitive impairment (MCI) in an individual. A composition comprising medium chain triglycerides (MCTs) can be administered to the individual in a daily dosage providing from about 15 g to about 45 g MCTs. The MCTs can include from about 51 wt % to about 90 wt % of octanoic acid. The daily dose can be provided in at least two servings, for example, 2 or 3 servings. Each serving can provide about 15 g MCTs and can include octanoic acid and decanoic acid in a weight ratio of, for example, about 60:about 40. The individual can be 65 years or older and / or have mild cognitive impairment (MCI).
Owner:SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA ET HUMAINES S E C +1

Supramolecular liquid crystal cream and preparation method thereof

The invention discloses supramolecular liquid crystal cream and a preparation method thereof, and relates to the technical field of cosmetic preparation. Comprising 0.3%-2% of supramolecular 10-hydroxydecanoic acid-alpha-bisabolol, 1.5%-5% of an emulsifier, 0.5%-3% of behenyl alcohol, 6.8%-23% of an emollient, 1.5%-6% of an emulsion stabilizer, 0.95%-2.85% of a thickener, 5%-14% of a humectant, 0.6%-1.8% of a preservative and a proper amount of water. Wherein the emulsion stabilizer comprises cetostearyl alcohol, and the mass ratio of the cetostearyl alcohol to the behenyl alcohol is (0.5-2): (0.5-3); the thickening agent comprises at least one of xanthan gum, microcrystalline cellulose / cellulose gum and bentonite. The specific thickening agent and the long-chain fatty alcohol emulsion stabilizer are added into the supramolecular system, so that ordered arrangement of liquid crystals in the supramolecular system is remarkably promoted, the mechanical strength of the lamellar liquid crystals is improved, and the stability of the supramolecular liquid crystal system is further improved.
Owner:GUANGZHOU FANWENHUA COSMETICS CO LTD

Preparation method of high-purity neodecanoic acid

The invention relates to the technical field of neodecanoic acid preparation, and provides a high-purity neodecanoic acid preparation method which comprises the following steps: S1, adding a catalyst into a high-pressure kettle, introducing CO, injecting nonene, and reacting to obtain a reaction solution; s2, mixing the reaction liquid with an extraction agent, feeding the mixture into an extractive distillation tower, and performing extraction and separation to obtain a first organic phase; s3, adding water into the first organic phase, washing and separating to obtain a second organic phase; s4, adding an alkaline additive into the second organic phase, layering to obtain an upper-layer organic phase, and carrying out reduced pressure distillation on the upper-layer organic phase to obtain neodecanoic acid; in the step S1, the raw materials of the catalyst comprise supported cobalt oxide and concentrated sulfuric acid; the supported cobaltous oxide is prepared from the following raw materials: water-soluble cobalt salt and boron nitride; in the step S2, the extraction agent comprises 1, 2-propylene glycol. According to the technical scheme, the problem of low purity of neodecanoic acid in related technologies is solved.
Owner:HEBEI RUIXINJINHUA NEW ENERGY TECH CO LTD

Process to produce low shear strength base oils

A lubricating fluid composition comprising i) a diester of polyethlene glycol esterified with a mixture of octanoic and deconoic acid where the polyethylene glycol may have 2-12 ethylene units and ii)
Owner:VANTAGE SANTOLUBES RES LLC

Fulvestrant formulations

Long term storage stable fulvestrant-containing compositions are disclosed. The compositions can include fulvestrant; a solvent selected from dimethyl sulfoxide (DMSO), glycofurol, N-methyl pyrrolidone, and mixtures thereof; an oil mixture selected from a mixture of caprylic and capric triglycerides, a mixture of caprylic, capric and linoleic triglycerides, a mixture of caprylic, capric and succinic triglycerides, and a mixture of propylene glycol dicaprylate and propylene glycol dicaprate; and a sustained release member selected from benzyl benzoate, dihydrolipoic acid, benzyl alcohol and lipoic acid. The fulvestrant-containing compositions have less than about 5% total impurities, on a normalized peak area response (“PAR”) basis as determined by high performance liquid chromatography (“HPLC”) at a wavelength of 223 nm, after at least about 24 months of storage at a temperature of from about 5° C. to about 25° C.
Owner:EAGLE PHARMACEUTICALS INC

Rust-proofing enhancer for PAG quenching liquid and preparation method thereof

The application discloses a rust-proof enhancer for PAG quenching liquid, and raw materials of the rust-proof enhancer include the following components in parts by weight: 40-45 parts of organic-inorganic rust-proof additive, 35-40 parts of pH regulator, 5-10 parts of non-ferrous metal rust-proof agent and 5-10 parts of antibacterial agent; the organic-inorganic rust-proof additive is a mixture of dicarboxylic acid, tricarboxylic acid, phytic acid, isomeric decanoic acid, fatty acid amide or fatty acid amine salt and sodium tungstate; the components synergistically generate a stable rust-proof film on the surface of metal, the rust-proof film has strong adhesion and can be firmly attached to the surface of metal, is less affected by the polarity of PAG, can effectively enhance the rust-proof performance of steel workpieces after quenching, and has no adverse effect on the properties such as the cloud point, viscosity, foam and cooling characteristics of the quenching liquid.
Owner:HUBEI CHENGXIANG TECH

Polyvinyl alcohol composite silicon oxide microcapsule temperature control material and preparation method thereof

The application discloses a polyvinyl alcohol composite silicon oxide microcapsule temperature control material and a preparation method thereof, and relates to the technical field of temperature control materials.The emulsion prepared by Pickering emulsification and covered by nanometer silicon oxide and decanoic acid-stearic acid eutectic crystals is mixed with a polyvinyl alcohol solution, and electrostatic spinning treatment is performed, so that a spinning film is obtained, namely the polyvinyl alcohol composite silicon oxide microcapsule temperature control material.The polyvinyl alcohol composite silicon oxide microcapsule temperature control material prepared by the application can provide all-weather radiation refrigeration and phase change energy storage, has excellent recycling performance, and has the characteristics of simple process, stable performance, safe and efficient, low cost, and can be widely applied to the fields of food, medicine and textiles.
Owner:GUANGXI UNIV

Juiciness enhancing compositions

PCT designated stageWO2025237817A1Food scienceEthyl palmitateEthyl ester
A flavor composition is provided. The flavor composition includes decanoic acid; ethyl palmitate; and 10-undecenoic acid.
Owner:GIVAUDAN SA

Il-22 oral, intra-rectal, or other gut-related compositions and methods of use thereof

To provide alternative methods of administration of IL-22, since currently there are limitations for administration of IL-22 for treatment of inflammatory diseases.SOLUTION: Provided is an oral, intra-rectal, or other gut-related pharmaceutical composition comprising an IL- 22 protein and an absorption enhancer selected from the group consisting of N(8-[2- hydroxybenzoyl]aino)caprylic acid (NAC), N-(10-[2-hydroxybenzoyl]amino)decanoic acid (NAD), a salt of the NAC or the NAD.SELECTED DRAWING: Figure 1
Owner:AMGEN INC