The invention discloses a heat-resistant insect-proofing polyurethane foam gap filling material comprising the raw materials: polyurethane, a styrene-acrylic emulsion, acrylic ester, diphenol propane, xylene, microlite, light calcium carbonate, diatomite, lindane, a talcum powder, zeolite, titanium dioxide, a talcum powder, a cellulose powder, magnesium oxide, nano calcium carbonate, a lamellar-structural mica powder, glass fiber, carbon fiber, quick lime, quartz sand, activated carbon, dichlorinated sodium isocyanurate, sodium potassium tartrate, fumaric acid, glutamine, inulin, borneol, acetyl trioctyl citrate, petroleum sodium sulfonate, sodium lauroyl glutamate, silicone oil, styrene, methyl triethoxysilane, a thickening agent, a silane coupling agent and a foaming agent. The heat-resistant insect-proofing polyurethane foam gap filling material has excellent heat resistant performance and insect-proofing performance.