66 results about "Tetradecane" patented technology

The application belongs to the technical field of oil and gas field development, and provides a phase permeability improver, a fracturing fluid system containing the same, and respective preparation methods and applications. The phase permeability improver is obtained by copolymerization and hydrolysis of acrylamide AM, a functional monomer 2-acrylamido-2-methylpropanesulfonic acid AMPS, and cationic hydrophobic monomers A and B; the cationic hydrophobic monomer A is at least one of tetradecyl dimethyl allyl ammonium chloride, hexadecyl dimethyl allyl ammonium chloride, and octadecyl dimethyl allyl ammonium chloride; the cationic hydrophobic monomer B is at least one of methacryloyloxyethyl trimethyl ammonium chloride, acryloyloxyethyl trimethyl ammonium chloride, and acryloyloxyethyldimethyl benzyl ammonium chloride; the phase permeability improver and the fracturing fluid system containing the same can significantly reduce the water phase permeability after fracturing operation, while having a smaller influence on the oil phase permeability, and have a significant effect of stabilizing oil and controlling water, and can significantly improve the stable production effect of fracturing operation in a low-permeability oil reservoir.

The invention discloses a phycomycete symbiotic system and application of the phycomycete symbiotic system in treatment of aquaculture tail water, and belongs to the technical field of tail water treatment. The phycomycete symbiotic system comprises chlorella, scenedesmus and activated sludge, and the initial inoculation dry weight ratio of the chlorella to the scenedesmus to the activated sludge is 1: 1: 6. And exogenously adding octanoyl-L-homoserine lactone or tetradecanoyl-L-homoserine lactone into the phycomycetes symbiotic system, so as to construct the phycomycetes symbiotic system with enhanced functions. On the basis of a mixed algae-bacteria symbiotic system with an optimized ratio, directional enhancement of functions is realized by virtue of quorum sensing signal molecules, the stability and resistance gene interception capability of the quorum sensing signal molecules under the stress of antibiotics are verified, and finally efficient purification of the aquaculture tail water is realized. According to the invention, the blank of the prior art in the aspects of advanced regulation and control of a phycomycete synergistic mechanism and synergistic treatment of emerging pollutants is filled up.

The invention discloses a high-salt-tolerance structured fracturing fluid and a preparation method thereof, and the fracturing fluid is prepared by taking a flowback fluid as a base fluid and adding a high-molecular polymer and a macromolecular surfactant. Wherein the high-molecular polymer is prepared by polymerizing five monomers, namely acrylamide, 2-acrylamido-2-methylpropanesulfonic acid, a hydrophobic monomer A, sodium p-styrenesulfonate and N-vinyl pyrrolidone; the hydrophobic monomer A is long-chain alkyl quaternary ammonium salt. The macromolecular surfactant is prepared by polymerizing five monomers, namely acrylamide, butyl acrylate, acrylic acid, a hydrophobic monomer B and sodium p-styrenesulfonate; the hydrophobic monomer B is selected from at least one of 2-(acrylamide) sodium dodecyl sulfonate, 2-(acrylamide) sodium tetradecanesulfonate and 2-(acrylamide) sodium hexadecanesulfonate. The fracturing fluid prepared by adopting the flowback fluid or saline water with the total mineralization degree of 85,000 as the base fluid still keeps good viscosity, and good salt resistance and sand-carrying performance are guaranteed.

Described herein are methods of synthesizing 1, 6-diazabicyclo [4.4. 4] tetradecane-1, 6-onium (in-DBD) cationic structures, methods of integrating in-DBD cationic structures into polymers, and the use of in-DBD polymers in electrochemical applications, such as anion exchange membranes (AEM). The configuration of the in-DBD enables the in-DBD to carry cationic charges through stable protons in an aliphatic cage formed by a three-dimensional structure of the in-DBD, and the in-DBD is anchored between two nitrogen atoms through symmetrical hydrogen bonds in bridgeheads. Through the synthesis method of in-DBD and the application thereof in various scenarios, an organic cation-hydroxide is realized that remains stable at extremely low hydration levels and high temperatures (80 DEG C, RHlt; 10%) and shows hydroxide stability several orders of magnitude higher than that of conventional cations.

The invention discloses a waste lithium ion battery recycling method, and belongs to the technical field of recycling of waste lithium ion batteries. The method comprises the following steps: leaching the positive electrode powder of the waste lithium ion battery in a deep eutectic solvent, and carrying out solid-liquid separation to obtain a leaching solution rich in heavy metals; the eutectic solvent is prepared from shikimic acid, catechol and tetradecyl dimethyl benzyl ammonium chloride. The deep-eutectic solvent is adopted for leaching, the leaching rate of nickel, cobalt, manganese and other heavy metals can be increased, meanwhile, leaching of impurity metals is avoided, and then it is avoided that a large amount of waste water is generated due to impurity removal. The metal ions and the eutectic solvent are separated by using the ion exchange resin, so that the eutectic solvent is recovered and can be repeatedly used, and the pure metal solution is obtained.

The application provides a crude oil direct oiling type spinning oil, a preparation method and application. The crude oil direct oiling type spinning oil comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of tetradecyl tetradec-9-enoate 25-35 parts and PEG-12 dipalmitate 65-75 parts. The composite smoothing agent is composed of specific compounds, so that the spinning oil can have smoothness, oil film strength and heat resistance; meanwhile, the friction coefficient of the yarn can be reduced and the uniformity of the yarn can be improved, and the quality of the yarn is good.

This invention relates to the application of 5-(tetradecoxy)-2-furoic acid (TOFA) in the preparation of drugs that inhibit osteoclast differentiation and function. Using a RANKL-induced mouse bone marrow macrophage osteoclast differentiation model, experiments demonstrated that TOFA can effectively inhibit osteoclast differentiation and function by inhibiting ROS and downregulating the expression of key osteoclast differentiation and function proteins such as Nfatc1, Src, and Ctsk. Furthermore, TOFA at concentrations of 40 μM and below showed no significant cytotoxicity, proving that TOFA can serve as a candidate compound for developing drugs that inhibit osteoclast differentiation and function, and for treating diseases caused by excessive activation of osteoclasts, thus possessing significant clinical application value. Additionally, by constructing a mouse ovariectomized osteoporosis model, the preventive and therapeutic effects of TOFA on estrogen-deficiency-induced osteoporosis were demonstrated.

To provide a bee repellent in order to prevent damage to honeybees, which are not the intended target of pesticides applied to crops or pesticides used to control carnivorous bees such as hornets and paper wasps. [Solution] A bee repellent comprising one or more components selected from tetradecane, furfuryl alcohol, cinnamyl alcohol, cinnamaldehyde, 3-methyl-2-butenal, methyl cinnamate, geranyl formate, allyl cyclohexanepropionate, isoquinoline, borneol, carvacrol, δ-dodecalactone, β-ionone, quinoline, butylamine, and citronella oil as active ingredients.

The invention discloses a fluorescent probe for detecting the viscosity of a cell membrane as well as a preparation method and application of the fluorescent probe, and belongs to the technical field of small molecule probes. The structural formula of the fluorescent probe is shown in the specification. The preparation method specifically comprises the following steps: (1) reacting 4-diethylaminoketonic acid and cyclohexanone in concentrated sulfuric acid, pouring into crushed ice, stirring, adding perchloric acid, stirring, standing and filtering; (2) dissolving 4-diethylaminobenzaldehyde in absolute ethyl alcohol, heating and refluxing, removing the solvent, and carrying out chromatography; and (3) dissolving benzotriazole-N, N, N ', N'-tetramethylurea hexafluorophosphate and N, N-diisopropylethylamine in N, N-dimethylformamide, stirring at normal temperature, adding a compound 43-(tetradecyl amino) propane-1-sulfonate, continuously stirring, removing the solvent, and carrying out chromatography to obtain the compound 43-(tetradecyl amino) propane-1-sulfonate. The fluorescent probe has excellent anchoring and imaging capabilities and viscosity-triggered near-infrared (NIR) fluorescence response characteristics, can be used for fluorescence imaging of cell membrane viscosity, and can also be used for viscosity imaging analysis of breast cancer mice.

The invention provides a marine fungus-derived petroleum degrading enzyme, a gene A6006 and application thereof, belongs to the crossing field of biological enzyme technology and environmental remediation, and provides the marine fungus-derived petroleum degrading enzyme, the amino acid sequence of which is shown as SEQ ID NO.2. The gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme can be used for degrading petroleum; the nucleotide sequence of the gene after being optimized by an escherichia coli codon is shown as SEQ ID NO. 1; the marine fungus-derived petroleum degrading enzyme provided by the invention can degrade dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, hexadecanoic acid, naphthalene, phenanthrene and pyrene; and the degradation effect on tetradecane, hexadecane and naphthalene is better.

The application belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of a key intermediate of plerixafor. The preparation method of the plerixafor intermediate 1,4,8,11-tetraazacyclotetradecane provided by the application uses N,N'-di(2-hydroxyethyl)-1,3-propanediamine as a starting material, hydroxyl is first activated by sulfuric acid, then ring formation is carried out under alkaline conditions, and then 1,3-propanediamine is used for ring opening, ring expansion and ring closure to obtain 1,4,8,11-tetraazacyclotetradecane. The process effectively avoids the introduction and removal of Ts-protecting groups by changing the reaction conditions, is simple to operate, shortens the reaction steps, and reduces the production working hours. The whole synthesis method is simple to operate and suitable for industrial production.

The invention discloses a non-irritant multipurpose long-acting degerming liquid, which is prepared from the following ingredients in percentage by mass: 0.1 to 0.5 percent of cationic polymer antibacterial agents, 1 to 4 percent of quaternary ammonium salt surfactants A, 0.5 to 2 percent of quaternary ammonium salt surfactants B, 1.5 to 5 percent of polyhydric alcohol humectants, 0.1 to 2 percent of alcohol solvents, 0.3 to 1 percent of plant natural polyphenols and 0.5 to 2 percent of optional essence. And the balance of deionized water. Wherein the cationic polymer antibacterial agent is preferably selected from polyhexamethylene biguanide hydrochloride (PHMB), and the quaternary ammonium salt surfactant is preferably selected from dodecyl dimethyl benzyl ammonium chloride (DDBAC) and tetradecyl dimethyl benzyl ammonium chloride (TDBAC). The benzalkonium chloride and the PHMB biguanide system are perfectly combined, efficient sterilization and disinfection are achieved, and meanwhile the long-acting antibacterial effect is achieved. The product contains natural plant components such as sugarcane essence, can effectively neutralize acidic peculiar smells such as sweat smell and foot odor, realizes zero irritation, and is especially suitable for people with sensitive skin and alcohol allergy.

The invention relates to a composite water control agent and application thereof. The composite water control agent comprises a polymeric monomer, nano silicon dioxide, an emulsifier, an initiator and water. Wherein the polymeric monomers are acrylic acid, acrylamide, 2-acrylamido-2-methylpropanesulfonic acid, 2-acrylamido tetradecane sulfonic acid and a surface and interface modified monomer; and the surface and interface modification type monomer is 3-methacryloyloxypropyltriethoxysilane.

The application belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of 1,4,8,11-tetraazacyclotetradecane. The preparation method is characterized in that 1,3-dibromopropane and cycloethylamine are used as starting materials to react, and then the obtained intermediate is subjected to ring opening, ring expansion and cyclization by 1,3-propanediamine to obtain 1,4,8,11-tetraazacyclotetradecane. The process effectively avoids the introduction and removal of Ts-protecting groups by changing the reaction conditions, is simple to operate, shortens the reaction steps, and reduces the production time. The whole synthesis method is simple to operate and suitable for industrial production.

Provided herein are polymorphs and their salts, methods of making these, compositions and pharmaceutical compositions containing these, kits containing these, and method of treating disease or conditions in a subject with the polymorphs, their salts, and compositions and pharmaceutical compositions containing these.

The invention discloses a thermoelectric material based on annealing-doping collaborative optimization and a preparation method thereof. The preparation method comprises the following steps: (1) dispersing carbon nanotubes in a poly (2, 5-bis (3-tetradecyl thiophene-2-yl) thieno [3, 2-b] thiophene) solution to obtain a suspension; and drying to remove the solvent and then carrying out annealing treatment. By constructing a continuous and stable carbon nanotube conductive network, the interface charge transfer barrier caused by PBTTT aggregation is eliminated, effective decoupling of S and sigma in the thermoelectric material is realized, and the inherent trade-off effect of S and sigma is broken. The preparation method provided by the invention has both process feasibility and performance superiority, and has potential application value.

The invention discloses a preparation method of a high-hardness transparent powder coating. The high-hardness transparent powder coating is prepared from 78%-83% of acrylic polyester, 10%-20% of a curing agent, 0.6%-1.2% of a flatting agent, 0.6%-1.2% of a breathable agent, 1%-3% of nano filler, 0.3%-0.5% of benzoin, 0.2%-0.5% of transparent degassing wax, 0.2%-0.5% of a dispersing agent and 0.1%-0.3% of an anti-settling agent. Wherein the curing agent is melted and ground tetradecanedioic acid, and the nano filler is nano silicon dioxide coated with a KH550 or KH560 silane coupling agent; the preparation method comprises the following steps: mixing and dispersing the acrylic polyester subjected to vacuum drying with other components, performing melt extrusion through a double-screw extruder, cooling, crushing and grading; tetradecanedioic acid is used as a curing agent and is fused and ground, and nano silicon dioxide is coated with a silane coupling agent, so that the crosslinking density and interfacial compatibility of the powder coating are remarkably improved; tetradecanedioic acid enables the reaction activity of the nano filler and acrylic polyester to be higher, meanwhile, the problem that traditional filler is prone to agglomeration is effectively solved through coating of the silane coupling agent on the nano filler, and the mechanical strength and light transmittance of the coating are directly enhanced.

This invention relates to the field of superhydrophobic anti-icing coating technology, specifically to a low-temperature phase change microcapsule superhydrophobic anti-icing coating and its preparation method. The specific technical solution is as follows: The preparation process involves ultrasonically dispersing superhydrophobic low-temperature phase change microcapsules in an organic solvent, adding an adhesive and a curing agent to the dispersion, stirring at room temperature, uniformly coating a composite layer onto a substrate, and curing to obtain the low-temperature phase change microcapsule superhydrophobic anti-icing coating. This invention utilizes a tetradecane / dodecyl alcohol binary eutectic phase change core material as an energy storage core material, and forms low-temperature phase change microcapsules by coating silica with interfacial polymerization, thereby achieving permanent curing of the core material, preventing leakage, and extending service life. After superhydrophobic modification, the superhydrophobic low-temperature phase change microcapsules are composited with polydimethylsiloxane to prepare a composite coating with superhydrophobic and latent heat release properties, achieving the purpose of anti-icing.

According to the method for treating the lithium precipitation mother liquor based on eutectic solvent extraction-precipitation, trioctylphosphine oxide and tetradecyl phosphoric acid are mixed to form a eutectic solvent system, trioctylphosphine oxide serves as a hydrogen bond acceptor, and the property of an eutectic solvent extraction-precipitation agent is regulated and controlled. Compared with an extraction-precipitation strategy of single tetradecyl phosphoric acid, by introducing trioctylphosphine oxide, the particle size of the precipitate is remarkably increased, an organic solvent is prevented from being used in the reverse extraction process, and meanwhile, the high-selectivity precipitation capacity of tetradecyl phosphoric acid TDPA to lithium is kept. The lithium can be enriched without isopropyl ether in the reverse extraction process, so that the isopropyl ether evaporation process in the extraction-precipitant circulation process is reduced, the overall energy consumption is reduced, and meanwhile, the performance attenuation of the extraction-precipitant caused by isopropyl ether oxidation is also avoided.

The present application provides a naphtha directional adsorption separation method, and relates to the technical field of petroleum chemical industry.The present application adopts a double desorption agent process flow, uses stronger adsorption force between high carbon alkanes (n-dodecane, n-tetradecane or n-hexadecane) and adsorbents, solves the problems of incomplete desorption of low carbon alkanes desorption agent and low separation yield, and thus significantly improves the separation efficiency of the process.Meanwhile, the use of low carbon alkanes (n-pentane or n-hexane) to replace high carbon alkanes on the adsorbents can avoid the residue of high carbon alkanes on the adsorbents, and affect the recycling of the adsorbents.The present application adopts the double desorption agent process flow, which can ensure high separation efficiency and improve the utilization rate of the adsorbents at the same time.The present application can efficiently separate n-alkanes in naphtha, and the separated n-alkanes can be used as high-quality cracking ethylene (propylene) raw materials;the adsorption residual oil rich in isomeric alkanes, naphthenes and aromatic hydrocarbons can be used as high-quality catalytic reforming aromatic hydrocarbon raw materials.

This invention provides an antibacterial and anti-adhesion double-balloon tracheostomy cannula and its preparation method. The invention involves constructing a coating material co-loaded with a newly developed tetradecyl antibacterial agent and chondroitin sulfate on both the cannula's surface and inner wall. This coating possesses both excellent hydrophilicity and strong antibacterial properties. The hydrophilicity makes it difficult for secretions to adhere; the antibacterial properties kill bacteria through contact, minimizing the development of drug resistance; and the anti-adhesion properties reduce the basis for biofilm formation. These three properties work synergistically to achieve full-chain protection from the "source" to the "process," significantly reducing the risk of luminal obstruction and VAP (ventilator-associated pneumonia), while also reducing the frequency of suctioning and mucosal damage, thus improving patient comfort.

The invention relates to a foam scrubbing agent and a preparation method thereof, and belongs to the technical field of oil and gas exploitation. The preparation method comprises the following steps: adding hydrogen peroxide into a mixed solution consisting of dodecyl dimethyl tertiary amine, tetradecyl dimethyl tertiary amine, octadecyl dimethyl tertiary amine, acrylic acid and a solvent, and reacting to generate amine oxide, so as to obtain a main agent of the foam scrubbing agent; the mass ratio of dodecyl dimethyl tertiary amine to tetradecyl dimethyl tertiary amine to octadecyl dimethyl tertiary amine to acrylic acid to H2O2 in hydrogen peroxide is (22-35): (15-25): (6-12): (5-10): (6-9); mixing the main agent of the foam scrubbing agent with the sulfamate chain extender for reaction; the mass ratio of the acrylic acid to the sulfamate chain extender in the main agent of the foam scrubbing agent is (0.35-1.1): (3-5). The foam scrubbing agent prepared by the invention can improve the recovery ratio of a gas well with high salinity and high gas condensate content, and solves the problems of water logging, output reduction and the like when the gas well productivity is extremely low in the later period of gas well exploitation.

The invention relates to an aluminosilicate mineral anion and cation combined collecting agent in a neutral environment. The aluminosilicate mineral anion and cation combined collecting agent is characterized by comprising 2-5 parts of a vegetable oil amide fatty acid collecting agent and 4-10 parts of tetradecyl tributyl phosphonium chloride. The preparation method is simple, and the raw materials are low in price and easy to obtain; the plant oil amide fatty acid collecting agent has carboxyl and amide, and the problems of low temperature resistance, mud resistance, adaptability and other pain points of traditional fatty acid collecting agents such as oleic acid are solved. The aluminosilicate mineral anion and cation combined collecting agent can be used in a neutral environment, the flotation performance of the aluminosilicate mineral anion and cation combined collecting agent is better than that of traditional fatty acid collecting agents such as oleic acid and lauryl amine, and the flotation recovery rate and grade can be effectively improved.

The invention relates to the technical field of mineral separation and purification of coal series kaolinite, in particular to a coal series kaolinite lattice type iron-titanium impurity long-chain amidoxime collecting agent based on defect site recognition and application of the coal series kaolinite lattice type iron-titanium impurity long-chain amidoxime collecting agent. The invention provides application of a coal series kaolinite lattice type iron-titanium impurity long-chain amidoxime collecting agent based on defect site recognition in coal series kaolinite lattice type iron-titanium impurity flotation separation. The long-chain amidoxime collecting agent is selected from one or more of octyl amidoxime, decyl amidoxime, dodecyl amidoxime and tetradecyl amidoxime. According to the long-chain amidoxime collecting agent, through directional adsorption of an amidoxime head group on Fe / Ti defect sites and the hydrophobic effect of a long-chain alkyl group, preferential collection and flotation of lattice type iron-titanium impurities in coal series kaolinite are achieved, and the long-chain amidoxime collecting agent has important significance on separation of the lattice type iron-titanium impurities in the coal series kaolinite.

The invention discloses mulching film grade PBAT and a preparation method thereof.The preparation method comprises the steps that a first catalyst is mixed with an esterification reactant of terephthalic acid and butanediol to obtain a terephthalic acid ester, and a second catalyst is mixed with an esterification reactant of adipic acid and butanediol to obtain an adipic acid ester; the first catalyst and the second catalyst are independently a mixture of benzamido glycolic acid and isopropyl titanate or a mixture of tris (trimethylsilane) phosphate and isopropyl titanate, and the first catalyst and the second catalyst are different; and mixing the terephthalic acid ester, the adipic acid ester and tetradecyl amide glycollic acid for polymerization reaction to obtain the mulching film grade PBAT. The preparation method is simple and easy to operate.

A composition comprising an acetic acid addition salt of Tetradecylaminocarbonyl-Dab-Val-Dab-OH, a process for preparing a cosmetic composition comprising mixing such a composition with one or more other components and the use of an acetic acid addition salt of Tetradecylaminocarbonyl-Dab-Val-Dab- OH to reduce or eliminate the growth of one or more microorganisms, preferably fungi, within a composition.

This invention relates to a method for determining related substances in pleroxafer using gas chromatography. The method includes detection using gas chromatography, wherein the gas chromatographic conditions are as follows: the stationary phase of the chromatographic column is phenyl-methylpolysiloxane; a temperature-programmed mode is used, wherein the temperature program includes: an initial temperature of 55-65°C held for 1-5 min, then increasing the temperature at 20-30°C / min to 300-320°C and holding for 45-60 min; an FID detector is used; an inert gas is used as the carrier gas; a split injection method is used with a split ratio of 8-12:1; wherein the related substances in pleroxafer include 1,4,8,11-tetraazacyclotetradecane. This invention achieves the detection of the related substance 1,4,8,11-tetraazacyclotetradecane in pleroxafer with high precision, specificity, accuracy, good repeatability, and good stability.

The invention relates to the technical field of quality control of camellia oleosa seed oil, and discloses a method for detecting authenticity and content of camellia oleosa seed oil based on characteristics of 5-tetradecyl dihydrofuran-2 (3H)-ketone, and qualitative judgment and quantitative analysis are performed on the camellia oleosa seed oil by analyzing the existence and content of the 5-tetradecyl dihydrofuran-2 (3H)-ketone in vegetable oil. And extracting, purifying and measuring the 5-tetradecyl dihydrofuran-2 (3H)-ketone in the vegetable oil by adopting the technologies of dissolving the vegetable oil with n-hexane, degreasing with a sulfonation method, deacidifying and purifying with a sodium sulfate aqueous solution, detecting with a gas chromatograph-mass spectrometer and the like. Whether the 5-tetradecyl dihydrofuran-2 (3H)-ketone exists or not and the content of the 5-tetradecyl dihydrofuran-2 (3H)-ketone in the vegetable oil are used for indicating the authenticity and the content of the camellia oleifera seed oil. The method is simple and feasible in technology and good in reproducibility, can realize accurate identification and content analysis of the camellia oleosa seed oil, and has a good application prospect.

This invention relates to a low-temperature resistant polymer cement-based waterproof coating, its preparation method, and its application. The coating consists of component A and component B. When used, components A and B are mixed in a mass ratio of 1:(0.5-2). Component A includes the following raw materials in parts by weight: 100-150 parts of ethylene-vinyl acetate copolymer emulsion, 10-20 parts of water-based nitrile latex, 2-5 parts of film-forming aid, 3-5 parts of plasticizer, 1-3 parts of defoamer, and 20-50 parts of deionized water. Component B includes the following raw materials in parts by weight: 100-150 parts of silicate cement, 50-60 parts of magnesium phosphate cement, 10-20 parts of gelatin-sodium alginate-coated n-tetradecane phase change microcapsules, and 10-20 parts of citric acid. This coating has advantages such as fast curing, good low-temperature flexibility, and strong freeze-thaw resistance.

The invention discloses a composition containing pydiflumetofen and epoxiconazole as well as a preparation method and application of the composition, and belongs to the technical field of pesticides. The bactericidal composition disclosed by the invention takes the pydiflumetofen and the epoxiconazole as main active components, has a synergistic effect, has a wider bactericidal spectrum, particularly has an excellent synergistic prevention and treatment effect on diseases caused by fusarium and rhizoctonia, and can effectively delay the generation of drug resistance of pathogenic bacteria, improve the prevention and treatment effect and prolong the lasting period; besides, tetradecyl methyl dihydroxyethyl ammonium bromide is introduced into the modified bentonite, the bactericidal effect can be enhanced, organic silicon is introduced into the surface of the modified silicon dioxide, the modified silicon dioxide can also be adsorbed on the surfaces of bacteria, the seepage force to cell walls is enhanced, and the bactericidal effect is further improved. On the whole, the dispersion stability is excellent, particle aggregation and caking are prevented, the uniformity and stability of the product in the storage and application process are guaranteed, and the sterilization effect is more excellent.