151 results about "Tetradecane" patented technology

The invention discloses a self-repairing high-energy-storage ice-snow-resistant double-layer composite microcapsule suitable for an asphalt surface layer and a preparation method and application thereof, and relates to a microcapsule preparation method and application thereof. The invention aims to solve the technical problems of poor core material release and self-healing effects, unstable shell wall material, low heat conductivity, easy leakage and single function of the existing self-repairing microcapsule for the asphalt pavement. The double-layer composite microcapsule is sequentially composed of an inner phase change microcapsule core, an inner phase change microcapsule shell, an outer self-repairing microcapsule core and an outer self-repairing microcapsule shell from inside to outside. Preparing an internal phase change microcapsule core from n-caprylic acid and tetradecane; preparing an internal phase change microcapsule shell by using a carbon nano tube and a double polymer; preparing an external self-repairing microcapsule core from bio-oil and a carbon nanotube; the outer self-repairing microcapsule shell is prepared from the carbon nano tube and the double polymer. Compared with a common asphalt pavement, the healing index of the surface layer of the asphalt pavement prepared from the double-layer composite microcapsule is improved by 8.1%-26.3%. The method can be used in highway fields.

The invention relates to a heat dissipation coating composition, a preparation method thereof and application of the heat dissipation coating composition in a battery protection plate, and belongs to the technical field of new energy heat dissipation coatings. According to the preparation method, methyl methacrylate, 2-vinylpyridine, methacrylamide, dipropylene glycol diacrylate, azodiisobutyronitrile and tetradecane are taken as raw materials, a coating dispersion liquid is prepared firstly, then hydroxylated graphene is subjected to polymerization coating by utilizing the coating dispersion liquid based on an in-situ polymerization method, a coating layer with amino and pyridine rings is constructed, and the coating layer with amino and pyridine rings is prepared. The preparation method comprises the following steps: coating a coating particle with amino boron nitride to obtain a coated particle, compounding the amino boron nitride onto the coated particle through addition of amino and epoxy groups by taking ethylene glycol diglycidyl ether containing double-terminal epoxy groups as a bridging agent to prepare a modified composite particle, and blending the modified composite particle with water-borne epoxy resin and other components to obtain the heat-dissipating coating composition. The coating has excellent heat dissipation performance, can still keep a good heat dissipation effect even after being heated and cooled for multiple times, and is suitable for being applied to the battery protection plate.

The invention relates to the field of packaging film materials, and particularly discloses a packaging film material with a temperature control function and a preparation process of the packaging film material. The packaging film material with the temperature control function comprises an upper layer and a lower layer, the lower layer comprises the following raw materials in parts by weight: 40-56 parts of a polyethylene matrix, 3-5 parts of phase change microcapsules and 4-8 parts of heat conduction fibers, core materials of the phase change microcapsules are tetradecane and paraffin, and capsule wall materials are calcium carbonate; the upper layer comprises the following raw materials in parts by weight: 45-58 parts of polyester; in addition, the preparation method has the advantage of improving the thermal insulation performance of the membrane material.

The application belongs to the technical field of oil and gas field development, and provides a phase permeability improver, a fracturing fluid system containing the same, and respective preparation methods and applications. The phase permeability improver is obtained by copolymerization and hydrolysis of acrylamide AM, a functional monomer 2-acrylamido-2-methylpropanesulfonic acid AMPS, and cationic hydrophobic monomers A and B; the cationic hydrophobic monomer A is at least one of tetradecyl dimethyl allyl ammonium chloride, hexadecyl dimethyl allyl ammonium chloride, and octadecyl dimethyl allyl ammonium chloride; the cationic hydrophobic monomer B is at least one of methacryloyloxyethyl trimethyl ammonium chloride, acryloyloxyethyl trimethyl ammonium chloride, and acryloyloxyethyldimethyl benzyl ammonium chloride; the phase permeability improver and the fracturing fluid system containing the same can significantly reduce the water phase permeability after fracturing operation, while having a smaller influence on the oil phase permeability, and have a significant effect of stabilizing oil and controlling water, and can significantly improve the stable production effect of fracturing operation in a low-permeability oil reservoir.

The invention discloses a self-repairing high-energy-storage ice-snow-resistant double-layer composite microcapsule as well as a preparation method and application thereof, and aims to solve the technical problems that an existing microcapsule phase-change material is easy to leak, single in heat energy source and monotonous in realization function. The double-layer composite microcapsule is sequentially composed of an inner phase change microcapsule core, an inner phase change microcapsule shell, an outer self-repairing microcapsule core and an outer self-repairing microcapsule shell from inside to outside. Wherein the internal phase change microcapsule core is composed of n-caprylic acid and tetradecane; the external self-repairing microcapsule core is formed by mixing hydrophobic hexamethylene diisocyanate and a carbon nano tube; the inner phase-change microcapsule shell and the outer phase-change microcapsule shell are formed by mixing carbon nanotubes and double polymers, and the double polymers are prepared from polyvinyl alcohol and methylated hexamethylol melamine resin; the preparation method comprises the following steps: preparing an inner high-energy-storage phase-change microcapsule, adding the inner high-energy-storage phase-change microcapsule into an outer microcapsule core solution, and dropwise adding the outer microcapsule core solution into an outer microcapsule shell solution to form a double-layer composite microcapsule; the microcapsule is used for preparing a coating and can be applied to the fields of coating self-repairing and ice and snow resistance.

The invention discloses a phycomycete symbiotic system and application of the phycomycete symbiotic system in treatment of aquaculture tail water, and belongs to the technical field of tail water treatment. The phycomycete symbiotic system comprises chlorella, scenedesmus and activated sludge, and the initial inoculation dry weight ratio of the chlorella to the scenedesmus to the activated sludge is 1: 1: 6. And exogenously adding octanoyl-L-homoserine lactone or tetradecanoyl-L-homoserine lactone into the phycomycetes symbiotic system, so as to construct the phycomycetes symbiotic system with enhanced functions. On the basis of a mixed algae-bacteria symbiotic system with an optimized ratio, directional enhancement of functions is realized by virtue of quorum sensing signal molecules, the stability and resistance gene interception capability of the quorum sensing signal molecules under the stress of antibiotics are verified, and finally efficient purification of the aquaculture tail water is realized. According to the invention, the blank of the prior art in the aspects of advanced regulation and control of a phycomycete synergistic mechanism and synergistic treatment of emerging pollutants is filled up.

The invention relates to anti-abnormal-sound low-noise ABS (acrylonitrile butadiene styrene) and a preparation method thereof. The anti-abnormal-sound low-noise ABS is prepared from the following raw material components: ABS resin, modified ceramic hollow microspheres, modified polyacrylate and auxiliaries, wherein the modified ceramic hollow microspheres are polymers obtained by grafting hydroxylated ceramic hollow microspheres with KH-570 and then polymerizing the grafted hydroxylated ceramic hollow microspheres with sodium acrylate; the modified polyacrylate is obtained by polymerizing sodium acrylate, butadiene, styrene and tetradecyl acrylate. According to the invention, the ABS resin, the modified ceramic hollow microspheres and the modified polyacrylate are compounded; compared with the prior art, the composite material disclosed by the invention has the advantages of good compatibility among various components, high bonding strength, effective reduction of noise and abnormal sound, guarantee of the mechanical strength of the composite material, solving of the problems in the prior art, and good application prospect.

The invention provides a composite extraction agent and application thereof in separation and recovery of lithium from lithium precipitation mother liquor. Relates to the technical field of composite extraction. The composite extraction agent comprises an extraction agent, a synergistic extraction agent and a diluent, the extraction agent comprises one or more of 1, 3-bis (4-fluorophenyl)-1, 3-propanedione, 2, 2-difluoro-1, 3-diphenyl-1, 3-propanedione, 1-phenyl-3-isoheptyl-1, 3-propanedione and benzoyl trifluoroacetone, and the diluent comprises one or more of 1, 3-bis (4-fluorophenyl)-1, 3-propanedione, 2, 2-difluoro-1, 3-diphenyl-1, 3-propanedione, 2, 2-difluoro-1, 3-diphenyl-1, 3-propanedione, 1-phenyl-3-isoheptyl-1, 3-propanedione and benzoyl trifluoroacetone. The synergistic extraction agent is prepared from one or more of tributyl phosphate, triisobutyl phosphate, triamyl phosphate, tributyl phosphine oxide and bis (4-fluorophenyl) phosphine oxide; the diluent comprises one or more of kerosene, sulfonated kerosene, tetradecane and tetradecanol. The composite extraction agent adopted by the invention has low requirement on pH, better acid and alkali resistance stability, small solution loss and good selective effect on lithium, the lithium recovery cost is reduced, and the comprehensive lithium extraction efficiency can reach 97.0% or above.

The invention discloses a salt-tolerant anti-calcium imbibition-oil displacement system suitable for a low-permeability compact oil reservoir and a preparation method thereof, the imbibition-oil displacement system comprises the following raw materials by weight: 0.05-1.5% of an amphiphilic head-based double hydrophobic chain surfactant, 0.05-1.5% of an amphiphilic head-based single hydrophobic chain surfactant, and the balance of water, wherein the double-hydrophilic-head-group double-hydrophobic-chain surface active agent is didecyl hydroxyl sulfonate, didodecyl hydroxyl sulfonate, ditetradecyl hydroxyl sulfonate or dihexadecyl hydroxyl sulfonate; the amphiphilic water head-based single hydrophobic chain surfactant is dodecyl amino acid salt, tetradecyl amino acid salt, hexadecyl amino acid salt or octadecyl amino acid salt. The imbibition-oil displacement system can be suitable for an oil reservoir formation water environment with low permeability, compactness, high total mineralization degree and high calcium ion content, can effectively reduce interfacial tension, and has imbibition-oil displacement performance.

The invention belongs to the technical field of oil-gas field development, and particularly relates to a foaming agent and a synthesis method and application thereof. The synthesis method comprises the following steps: adding 1-amino-3, 6, 9, 12, 15, 18-hexaoxaheneicosan-21-acid and ethanol into a high-pressure reaction kettle, stirring and dissolving, adding 4-(2-bromoethyl) sodium benzenesulfonate, continuously stirring, adjusting the pH value to 8-9 by using sodium hydroxide, heating and preserving heat, and adjusting the pH value to 8-9 by using sodium hydroxide during the period; and adding bromotetradecane into the solution, heating and refluxing, adjusting the pH value to 8-9 by using sodium hydroxide during heating and refluxing, carrying out reduced pressure distillation to obtain a viscous solid, and recrystallizing by using normal hexane to obtain a product, namely the foaming agent. The foaming agent provided by the invention has the advantages of strong foaming power, good stability and low interfacial tension.

The invention discloses a high-salt-tolerance structured fracturing fluid and a preparation method thereof, and the fracturing fluid is prepared by taking a flowback fluid as a base fluid and adding a high-molecular polymer and a macromolecular surfactant. Wherein the high-molecular polymer is prepared by polymerizing five monomers, namely acrylamide, 2-acrylamido-2-methylpropanesulfonic acid, a hydrophobic monomer A, sodium p-styrenesulfonate and N-vinyl pyrrolidone; the hydrophobic monomer A is long-chain alkyl quaternary ammonium salt. The macromolecular surfactant is prepared by polymerizing five monomers, namely acrylamide, butyl acrylate, acrylic acid, a hydrophobic monomer B and sodium p-styrenesulfonate; the hydrophobic monomer B is selected from at least one of 2-(acrylamide) sodium dodecyl sulfonate, 2-(acrylamide) sodium tetradecanesulfonate and 2-(acrylamide) sodium hexadecanesulfonate. The fracturing fluid prepared by adopting the flowback fluid or saline water with the total mineralization degree of 85,000 as the base fluid still keeps good viscosity, and good salt resistance and sand-carrying performance are guaranteed.

The invention belongs to the technical field of oil-gas field development, and provides a phase permeability improver, a fracturing fluid system containing the phase permeability improver, and preparation methods and applications of the phase permeability improver and the fracturing fluid system. The phase permeability improver is obtained by copolymerization and hydrolysis of acrylamide (AM), a functional monomer 2-acrylamido-2-methylpropanesulfonic acid (AMPS) and cationic hydrophobic monomers A and B, the cationic hydrophobic monomer A is at least one of tetradecyl dimethyl allyl ammonium chloride, hexadecyl dimethyl allyl ammonium chloride and octadecyl dimethyl allyl ammonium chloride; the cationic hydrophobic monomer B is at least one of methacryloyloxyethyl trimethyl ammonium chloride, acryloyloxyethyl trimethyl ammonium chloride and acryloyloxyethyl dimethyl benzyl ammonium chloride; the phase permeability improver and the fracturing fluid system containing the phase permeability improver can obviously reduce the water phase permeability after fracturing construction, meanwhile, the influence on the oil phase permeability is small, the oil stabilizing and water controlling effects are obvious, and the low-permeability oil reservoir fracturing construction yield stabilizing effect can be obviously improved.

The invention relates to a method for reducing the content of 2, 6-diaminotoluene and / or 2, 4-diaminotoluene in a polyol, in particular in a recovered polyol, in which a polyol containing 2, 6-diaminotoluene and / or 2, 4-diaminotoluene is reacted with at least one compound selected from the group consisting of a), b) and c), in which the polyol containing 2, 6-diaminotoluene and / or 2, 4-diaminotoluene is reacted with at least one compound selected from the group consisting of a), b) and c), wherein: a) one or more epoxy-functional compounds, preferably dodecyl / tetradecyl glycidyl ethers, b) one or more anhydrides, in particular phthalic anhydrides, and c) one or more aldehydes, preferably benzaldehyde.

Described herein are methods of synthesizing 1, 6-diazabicyclo [4.4. 4] tetradecane-1, 6-onium (in-DBD) cationic structures, methods of integrating in-DBD cationic structures into polymers, and the use of in-DBD polymers in electrochemical applications, such as anion exchange membranes (AEM). The configuration of the in-DBD enables the in-DBD to carry cationic charges through stable protons in an aliphatic cage formed by a three-dimensional structure of the in-DBD, and the in-DBD is anchored between two nitrogen atoms through symmetrical hydrogen bonds in bridgeheads. Through the synthesis method of in-DBD and the application thereof in various scenarios, an organic cation-hydroxide is realized that remains stable at extremely low hydration levels and high temperatures (80 DEG C, RHlt; 10%) and shows hydroxide stability several orders of magnitude higher than that of conventional cations.

The present invention relates to a curable and electrochemically debondable one-component (1K) structural adhesive composition comprising a) a (meth)acrylate monomer selected from the group consisting of hydroxypropyl acrylate, hydroxypropyl methacrylate, hydroxybutyl methacrylate, isobornyl acrylate, isobornyl methacrylate, methyl methacrylate and mixtures thereof; b) an electrolyte selected from the group consisting of 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, 1-pentyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, 1-hexyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, 1-heptyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, 1-octyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, 1-nonyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, 1-decyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, 1-dodecyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, 1-tetradecyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, 1-hexadecyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, 1-octadecyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide, trihexyltetradecylphosphonium bis(trifluoromethylsulfonyl) amide, and mixtures thereof; c) a co-polymerisable acid; d) an initiator; e) a core shell toughener; and f) a toughener. The composition according to the present invention can withstand harsh conditions (high temperature and high humidity) while maintaining adhesive and debonding properties.

Double-layer composite microcapsules suitable for asphalt surface layers that are both self-repairing, have high energy storage, and are resistant to ice and snow, as well as their preparation method and application, relate to a microcapsule preparation method and its application. The invention aims to address the technical problems of existing self-repairing microcapsules for asphalt pavements, such as poor core material release and self-healing effects, unstable shell wall materials, low thermal conductivity, easy leakage, and single functionality. The double-layer composite microcapsules of the present invention are composed, from the inside to the outside, of an inner phase-change microcapsule core, an inner phase-change microcapsule shell, an outer self-repairing microcapsule core, and an outer self-repairing microcapsule shell; the inner phase-change microcapsule core is prepared using n-octanoic acid and tetradecane; the inner phase-change microcapsule shell is prepared using carbon nanotubes and a double polymer; the outer self-repairing microcapsule core is prepared using bio-oil and carbon nanotubes; and the outer self-repairing microcapsule shell is prepared using carbon nanotubes and a double polymer. Compared to ordinary asphalt pavement, the healing index of the asphalt pavement surface layer prepared using the double-layer composite microcapsules is increased by 8.1% to 26.3%. It can be used in the highway field.

The invention relates to a preparation method of a diformaldehyde gemini surfactant. Mannich reaction is adopted, a long-chain fatty amine component, glyoxal and sodium hydrogen sulfite are used as reaction raw materials, a single variable method is used for controlling reaction conditions, and the optimal conditions of the reaction are explored as follows: the reaction temperature is 60 DEG C, the reaction time is 5 h, and the molar ratio of glyoxal to sodium hydrogen sulfite is 1: 2.3. Then, all products are dissolved with trichloromethane, ethyl acetate is added into the solution to separate out the products, the products are treated through a secondary crystallization method, the product calculation yield is obtained, and the content of 1, 2-bis (dodecyl amino) ethane-1, 2-sodium disulfonate, 1, 2-bis (tetradecyl amino) ethane-1, 2-sodium disulfonate, 1, 2-bis (hexadecyl amino) ethane-1, 2-sodium disulfonate, 1, 2-bis (hexadecyl amino) ethane-1, 2-sodium disulfonate and 1, 2-bis (hexadecyl amino) ethane-1, 2-sodium disulfonate is measured. The synthetic yields of the 1, 2-sodium disulfonate are 65.8%, 67.5% and 76.8% respectively. And characterization is carried out through a nuclear magnetic resonance spectrometer and an infrared spectrometer.

The invention discloses a collecting agent for flotation of picromerite at high temperature and application of the collecting agent, the collecting agent is alkyl benzene sulfonic acid isopropanolamine salt, specifically any one of dodecyl benzene sulfonic acid isopropanolamine salt, tetradecyl benzene sulfonic acid isopropanolamine salt and hexadecyl benzene sulfonic acid isopropanolamine salt; the collecting agent is mainly used for recovering picromerite through flotation at high temperature, the floatability of picromerite can be effectively enhanced, and the flotation recovery rate is increased. By adding the collecting agent in stages, non-selective adsorption of the collecting agent on the surface of non-target minerals can be reduced, the problem that the grade of picromerite flotation concentrate is low in high-temperature weather is solved, and efficient recovery of picromerite in the high-temperature environment in summer is achieved.

The invention discloses a waste lithium ion battery recycling method, and belongs to the technical field of recycling of waste lithium ion batteries. The method comprises the following steps: leaching the positive electrode powder of the waste lithium ion battery in a deep eutectic solvent, and carrying out solid-liquid separation to obtain a leaching solution rich in heavy metals; the eutectic solvent is prepared from shikimic acid, catechol and tetradecyl dimethyl benzyl ammonium chloride. The deep-eutectic solvent is adopted for leaching, the leaching rate of nickel, cobalt, manganese and other heavy metals can be increased, meanwhile, leaching of impurity metals is avoided, and then it is avoided that a large amount of waste water is generated due to impurity removal. The metal ions and the eutectic solvent are separated by using the ion exchange resin, so that the eutectic solvent is recovered and can be repeatedly used, and the pure metal solution is obtained.

The invention belongs to the field of water treatment, and more particularly to a positively charged quaternary ammonium salt polymer catalyst and its preparation method and application. The catalyst provided by the present invention is made of a positively charged quaternary ammonium salt precursor through polymerization and anion exchange, and the positively charged quaternary ammonium salt precursor is the reaction product of acrylate and halogenated alkane; the acrylate is one or more of dimethylaminoethyl acrylate, dimethylaminoethyl methacrylate and 3 (dimethylamino) ethyl acrylate; the halogenated alkane is one or more of undecane bromide, dodecane bromide, tetradecane bromide, hexadecane bromide, eicosane bromide, dodecane chloride, tetradecane chloride and hexadecane chloride. The catalyst provided by the present invention has good stability and antibacterial properties, can efficiently and selectively catalyze the degradation of organic pollutants by peroxide, has important practical significance for removing wastewater rich in organic pollutants, and has a wide range of applications in water pollution control and water environment restoration.

The invention provides an aqueous solution with a diamine component, wherein said diamine component consists of least 75 to 100 weight-% based on the total weight of the diamines in the aqueous solution of 5-N-carboxamido-2-pyrrolidone-N-n-dodecyl propane-1,3-diamine, also referred to as Py-C12, or at least 35 weight-% of 5-N-carboxamido-2-pyrrolidone-N-n-tetradecyl propane-1,3-diamine, also referred to as Py-C14 for attaching said diamine to a material, wherein the solution has a pH of 8 or less and does not comprise a solubilizer. These solutions are particularly useful as biocides. In a related aspect, the invention provides a method for attaching a diamine component according to the invention to a material.

The application provides a crude oil direct oiling type spinning oil, a preparation method and application. The crude oil direct oiling type spinning oil comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of tetradecyl tetradec-9-enoate 25-35 parts and PEG-12 dipalmitate 65-75 parts. The composite smoothing agent is composed of specific compounds, so that the spinning oil can have smoothness, oil film strength and heat resistance; meanwhile, the friction coefficient of the yarn can be reduced and the uniformity of the yarn can be improved, and the quality of the yarn is good.

The invention discloses a method for beneficiating uranium-containing gold ore. According to the mineral composition characteristics of the uranium-containing gold ore and the distribution characteristics of useful minerals, the uranium-containing gold ore is crushed, ground and classified, the coarse-grained ore is firstly recovered by a shaking table, and then a flotation agent composed of a water glass inhibitor, a sodium hydrosulfide activator, an amyl xanthate and an alkylaminocarboxylic acid combined collector is used to flotate and recover the gold; the fine-grained ore is recovered by centrifugal reselection, and then the coarse-grained and fine-grained tailings are combined, and a flotation agent composed of a lead nitrate and ferric sulfate combined activator, an isooctyl phosphate and a tetradecylamine combined collector is used to flotate and recover uranium, and finally the uranium is further recovered by strong magnetism, which not only realizes the comprehensive recovery of gold and uranium, but also can discard most of the tailings. The gold grade in the total gold concentrate is 56.34g / t, the recovery rate is 97.08%, the uranium grade in the total uranium concentrate is 0.196%, the recovery rate is 70.59%, the tailings yield is 87.06%, the gold grade is 0.14g / t, and the uranium grade is 0.003%.

The invention provides a crude oil direct oiling type spinning oil agent, a preparation method and application, the crude oil direct oiling type spinning oil agent comprises 65-75% of a composite smoothing agent, and the composite smoothing agent is composed of 25-35 parts of tetradecyl tetradecane-9-olefine acid ester and 65-75 parts of PEG-12 dipalmitate. Specific compounds are selected to form the composite smoothing agent, so that the spinning oil agent has smoothness, oil film strength and heat resistance at the same time; meanwhile, the friction coefficient of the yarn can be reduced, the uniformity of the yarn is improved, and the yarn quality is good.

The invention discloses a foam drainage agent with hydrate inhibition performance and a preparation method and application thereof. The foam drainage agent provided by the invention is prepared from PVCap-TBA and a betaine compound, the PVCap-TBA is prepared from N-vinyl caprolactam and tert-butyl acrylate, and the PVCap-TBA is prepared from N-vinyl caprolactam The betaine compound is selected from two or more of cocamidopropyl betaine, dodecyl dimethyl betaine and tetradecyl dimethyl betaine, and the betaine compound is compounded by two or more of cocamidopropyl betaine, dodecyl dimethyl betaine and tetradecyl dimethyl betaine. The foam drainage agent provided by the invention has the advantages of hydrate inhibition performance, low temperature resistance, hypersalinity resistance, methanol resistance and the like, can effectively perform drainage gas recovery construction in a deep sea shaft, and ensures that natural gas in the deep sea shaft can be continuously and stably produced.

This invention relates to the application of 5-(tetradecoxy)-2-furoic acid (TOFA) in the preparation of drugs that inhibit osteoclast differentiation and function. Using a RANKL-induced mouse bone marrow macrophage osteoclast differentiation model, experiments demonstrated that TOFA can effectively inhibit osteoclast differentiation and function by inhibiting ROS and downregulating the expression of key osteoclast differentiation and function proteins such as Nfatc1, Src, and Ctsk. Furthermore, TOFA at concentrations of 40 μM and below showed no significant cytotoxicity, proving that TOFA can serve as a candidate compound for developing drugs that inhibit osteoclast differentiation and function, and for treating diseases caused by excessive activation of osteoclasts, thus possessing significant clinical application value. Additionally, by constructing a mouse ovariectomized osteoporosis model, the preventive and therapeutic effects of TOFA on estrogen-deficiency-induced osteoporosis were demonstrated.

To provide a bee repellent in order to prevent damage to honeybees, which are not the intended target of pesticides applied to crops or pesticides used to control carnivorous bees such as hornets and paper wasps. [Solution] A bee repellent comprising one or more components selected from tetradecane, furfuryl alcohol, cinnamyl alcohol, cinnamaldehyde, 3-methyl-2-butenal, methyl cinnamate, geranyl formate, allyl cyclohexanepropionate, isoquinoline, borneol, carvacrol, δ-dodecalactone, β-ionone, quinoline, butylamine, and citronella oil as active ingredients.

Disclosed herein are compounds of Formula (I) having protective group of ketal used as intermediates for preparing 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-((((1r,4r)-4-hydroxy-4-methylcyclohexyl)methyl)amino)-3-nitrophenyl) sulfonyl)-4-(2-((S)-2-(2-isopropylphenyl) pyrrolidin-1-yl)-7-azaspiro[3.5]nonan-7-yl)benzamide (Sonrotoclax), and processes for preparing compounds of Formula (I), especially 1,5-dioxa-11-azadispiro[5.1.5.1]tetradecane.

The invention discloses a fluorescent probe for detecting the viscosity of a cell membrane as well as a preparation method and application of the fluorescent probe, and belongs to the technical field of small molecule probes. The structural formula of the fluorescent probe is shown in the specification. The preparation method specifically comprises the following steps: (1) reacting 4-diethylaminoketonic acid and cyclohexanone in concentrated sulfuric acid, pouring into crushed ice, stirring, adding perchloric acid, stirring, standing and filtering; (2) dissolving 4-diethylaminobenzaldehyde in absolute ethyl alcohol, heating and refluxing, removing the solvent, and carrying out chromatography; and (3) dissolving benzotriazole-N, N, N ', N'-tetramethylurea hexafluorophosphate and N, N-diisopropylethylamine in N, N-dimethylformamide, stirring at normal temperature, adding a compound 43-(tetradecyl amino) propane-1-sulfonate, continuously stirring, removing the solvent, and carrying out chromatography to obtain the compound 43-(tetradecyl amino) propane-1-sulfonate. The fluorescent probe has excellent anchoring and imaging capabilities and viscosity-triggered near-infrared (NIR) fluorescence response characteristics, can be used for fluorescence imaging of cell membrane viscosity, and can also be used for viscosity imaging analysis of breast cancer mice.

The invention provides a marine fungus-derived petroleum degrading enzyme, a gene A6006 and application thereof, belongs to the crossing field of biological enzyme technology and environmental remediation, and provides the marine fungus-derived petroleum degrading enzyme, the amino acid sequence of which is shown as SEQ ID NO.2. The gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme can be used for degrading petroleum; the nucleotide sequence of the gene after being optimized by an escherichia coli codon is shown as SEQ ID NO. 1; the marine fungus-derived petroleum degrading enzyme provided by the invention can degrade dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, hexadecanoic acid, naphthalene, phenanthrene and pyrene; and the degradation effect on tetradecane, hexadecane and naphthalene is better.