Medicine thermal insulation box with precise temperature control function, thermal insulation method and novel application of tetradecane

An incubator and tetradecane technology, applied in chemical instruments and methods, materials for heat exchange, types of packaging items, etc., can solve the problems of drug failure, medical safety, complex operation process, and lower than 0°C, and achieve protection of cold storage The effect of drug quality

Inactive Publication Date: 2015-08-05
北京优冷冷链科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the hot season when the daily average temperature of 2-8°C refrigerated medicines in the prior art is higher than 8°C, the antifreeze incubators used for refrigerated transportation basically include a box body, and a refrigerated medicine holding chamber is arranged in the box body, and then the 2 ~ 8 ℃ refrigerated medicines and the cold source (ice box, ice bag, etc.) with a phase transition temperature of about 0 ℃ after freezing are placed in it, and the heat released by the cold source balances the heat transferred to the medicine holding cavity by the cold source to achieve refrigeration Low-temperature storage of medicines with a temperature not higher than the upper limit of 8°C; this structure has the risk that the cold source will directly contact the refrigerated medicines, and cause the temperature of the medicines to be lower than the specified lower limit storage temperature of 2°C, which may damage the refrigerated medicines. Cannot meet the verification requirements of the new version of GSP: refrigerated medicines are strictly required to be accurately stored in cold storage at 2-8°C, neither higher than the upper limit temperature of 8°C nor lower than the specified lower limit temperature of 2°C, and the medicine box should not be in direct contact with the cold source
[0003] The improved method in the prior art is to place a partition between the cold source and the refrigerated medicine to prevent direct contact between the refrigerated medicine and the cold source, or to place the cold source in the slot on the inner wall of the incubator; although this method meets the requirements of the GSP drug The packing box should not be in direct contact with the cold source; however, because the supercooled cooling capacity of the cold source only delays its transfer speed, it has not been effectively and properly neutralized. After a long time, the supercooled cooling capacity will still be transferred to the refrigerator. In medicines, if the temperature of refrigerated medicines is 2°C lower than the lower limit storage temperature stipulated for medicines, there is a risk of freezing and damaging the refrigerated medicines, leading to the failure of medicines and causing medical safety accidents
[0004] The updated and improved method in the prior art is: place a partition between the cold source and the refrigerated medicine to prevent direct contact between the refrigerated medicine and the cold source, or place the cold source in the slot on the inner wall of the incubator; The supercooled cold source whose surface temperature is lower than 0°C is placed in an environment with a temperature higher than 2°C for more than 2 hours in advance to release the supercooled cooling energy so that the surface temperature is not lower than 0°C; although this method meets the GSP regulations Refrigerated medicines strictly require precise temperature control at 2-8°C, and also meet the regulations that refrigerated medicine packaging boxes should not be in direct contact with cold sources; however, there are the following obvious defects: the cold source that has been frozen must be refrigerated more than 2 hours in advance. Anti-overcooling release cooling operation, the operation process of this process is complicated, and the time required is too long to meet the requirements of modern cold chain logistics, which is ready-to-use, fast, and simple, and is not suitable for mass logistics operations; moreover, the cold source is supercooled. Dur

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  • Medicine thermal insulation box with precise temperature control function, thermal insulation method and novel application of tetradecane
  • Medicine thermal insulation box with precise temperature control function, thermal insulation method and novel application of tetradecane
  • Medicine thermal insulation box with precise temperature control function, thermal insulation method and novel application of tetradecane

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Experimental program
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Effect test

Embodiment 1

[0040] see figure 1 and figure 2 , the precise temperature control drug incubator of the present embodiment includes an incubator box 1 provided with a cavity and an incubator upper cover 2 that can be covered on the incubator box;

[0041] The accommodating cavity is divided into a medicine accommodating cavity 4 and a cold source accommodating cavity 5 by a heat storage partition 3;

[0042] The heat storage separator 3 includes a casing 30 and a heat storage agent 31 sealed in the casing 30 with a phase transition temperature of 3-7°C.

[0043] The precise temperature-controlled medicine incubator of the present embodiment or the medicine antifreeze and heat preservation method of the present invention, when used in the hot season when the daily average temperature of the environment is higher than 8 degrees Celsius, put the frozen phase transition temperature in the cold source accommodation chamber 5. A low-temperature cold source at about 0°C is placed in the medicine...

Embodiment 2

[0051] The present embodiment provides a kind of antifreeze and heat preservation method for medicines in the hot season when the average daily temperature of the environment is higher than 8 degrees Celsius, comprising the following steps:

[0052] S10, sealing a heat storage agent with a phase change temperature of 3-7°C in the casing to form a heat storage separator;

[0053] S20, placing the heat storage separator in a normal temperature environment with a temperature higher than 8°C, so that the heat storage agent therein absorbs the heat of the environment and presents a liquid state;

[0054] S30. Place the heat storage partition in the cavity of the incubator, and divide the cavity inside the incubator into a cold source cavity and a medicine cavity;

[0055] S40. Put a frozen low-temperature cold source with a phase transition temperature of about 0°C in the cold source storage cavity, and put refrigerated medicines at 0-10°C taken out of the refrigerated storage devi...

Embodiment 3

[0059] This embodiment provides a method for antifreezing and heat preservation of refrigerated medicines in the cold season when the daily average temperature of the environment is lower than 8 degrees Celsius, comprising the following steps:

[0060] D10. Seal the heat storage agent with a phase change temperature of 3-7°C in the shell to make a heat storage separator;

[0061] D20. Place the heat storage separator in an environment with a temperature higher than 8°C, so that the heat storage agent in it absorbs the heat of the environment and presents a liquid state;

[0062] D30. Place the heat storage partition in the cavity of the incubator, and divide the cavity inside the incubator into a cold source cavity and a refrigerated medicine cavity;

[0063] D40. Put a low-temperature cold source with a phase transition temperature of about 0°C that has been stored in an environment with a temperature higher than 8°C in the cold source storage cavity; Refrigerated medicines ...

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Abstract

The invention discloses a medicine thermal insulation box with a precise temperature control function, a medicine thermal insulation method, and a novel application of tetradecane. The medicine thermal insulation box with the precise temperature control function comprises a thermal insulation box body having a containing chamber, and an upper thermal insulation box cover which can be covered on the thermal insulation box body. The containing chamber is divided into a medicine containing chamber and a cold source containing chamber by a heat accumulation partitioning board. The heat accumulation partitioning board comprises a housing, and a heat accumulation agent which is sealed inside the housing and is of a phase-change temperature of 3-7 degrees centigrade. The medicine thermal insulation box with the precise temperature control function or the medicine anti-freezing thermal insulation method can utilize the heat energy of the heat accumulation agent to neutralize the cold energy of the cold source; in the process of delivering the heat energy, the heat accumulation agent can be solidified and discharge the heat energy when the temperature of the heat accumulation agent drops to the phase-change temperature, so as to further neutralize the cold energy of the cold source, thereby preventing the medicine from being frozen due to the excessively low temperature.

Description

technical field [0001] The present invention relates to the anti-freezing, cold storage and heat preservation during the transportation of refrigerated medicines, in particular to a refrigerated medicine incubator with precise temperature control used in the transportation of refrigerated medicines, a method for antifreeze and heat preservation of refrigerated medicines, and a new application of tetradecane, a medicine incubator with precise temperature control . Background technique [0002] In the hot season when the daily average temperature of 2-8°C refrigerated medicines in the prior art is higher than 8°C, the antifreeze incubators used for refrigerated transportation basically include a box body, and a refrigerated medicine holding chamber is arranged in the box body, and then the 2 ~ 8 ℃ refrigerated medicines and the cold source (ice box, ice bag, etc.) with a phase transition temperature of about 0 ℃ after freezing are placed in it, and the heat released by the col...

Claims

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Application Information

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IPC IPC(8): B65D81/18B65D81/24C09K5/06
Inventor 李辉群
Owner 北京优冷冷链科技有限公司
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