A device (1) for dispensing a mist of a
dose of an
ophthalmic liquid, comprising, a
discharge opening (93) for the mist, a
mixing chamber (21) being in fluid flow communication with the
discharge opening (93), an
air chamber (50), being in fluid flow communication with the
mixing chamber (21), a container (30) holding a first volume of liquid corresponding to a plurality of doses of the liquid (L), such as a collapsible liquid container or a liquid container having a movable bottom, a
dose holding chamber (92) for holding a second volume of the liquid and being in fluid flow communication with the
mixing chamber (21), and being in fluid flow communication with or configured for being in fluid flow communication with the container (30), a first drive (52, 58) operable to expel air from the
air chamber (50), a second drive with a
piston (238), the second drive being operable to supply the second volume of the liquid from the container (30) to the
holding chamber (92) and for emptying said container (30) by repetitive delivery cycles each delivering a single
dose from the first volume of liquid contained therein towards the
holding chamber (92) the
air chamber (50) being in fluid flow communication with the holding chamber (92) for the expelled air to drive the second volume of liquid from the holding chamber (92) into said mixing chamber (21) by the expelled air characterised in that the
piston (238) is displaced from an advanced position to an at least partially retracted position and / or from a retracted position to an at least partially advanced position more than once during the delivery cycle.