41 results about "Pentadecane" patented technology

The invention relates to the field of plasma separation and detection, in particular to a composition for separating plasma and a using method thereof. The composition comprises: a phase change component, which is selected from n-alkanes, which are selected from at least one of n-tetradecane, n-pentadecane, n-hexadecane, n-heptadecane, n-octadecane, n-nonadecane, n-eicosane, n-heneicosane or n-docosane; a liquid phase carrier component, wherein the liquid phase carrier component is selected from silicone oil; the structural framework and rheology regulation and control component comprises fumed silica, and the structural framework and rheology regulation and control component comprises fumed silica; the dispersion and stabilization auxiliary agent component is selected from at least one of TiO2 and BaSO4, the density adjusting filler component is selected from at least one of TiO2 and BaSO4, and the dispersion and stabilization auxiliary agent component comprises a silane coupling agent. According to the device, plasma and blood cells can be reliably, rapidly and effectively separated only through one-time low-temperature centrifugation, and remixing caused by transportation jolting can be avoided.

Administration of pentadecanoylcarnitine or pentadecanoic acid is provided for prevention, management or treatment of aggression, allergies, allergic rhinitis, Alzheimer's disease, anxiety and anxiety disorders, amyotrophic lateral sclerosis, arthritis, asthma, atherosclerosis, attention-deficit hyperactivity disorder, bipoloar disorder, brain damage, cancer, cardiovascular disease, cholestatic pruritis, depression, chronic obstructive pulmonary disease (COPD), cocaine abuse, cough, dermatitis, depression, drug-seeking behavior, gastrointestinal disorders, facial erythema associated with rosacea, glaucoma, hepatic diseases, hyperactive bladder, hypersensitivity disorders, hypertension, impulsivity, inflammation, mental disorders and conditions, metabolic disorders, migraines, nasal and sinus congestion, nausea, neuropathic pain with and symptoms of multiple sclerosis, neurological and neuropsychiatric disorders, obesity, obsessive-compulsive disorders, opioid-induced respiratory depression, osteoarthritis, pain, Parkinson disease, pathological gambling, peptic ulcers, schizophrenia, sleep disorders, spinal cord injury, tardive dyskinesia, tics and behavioral problems with Tourette's syndrome; as well as for supporting appetite, cardiovascular health, hematologic health, memory, metabolic health, mood, prolonged REM sleep, renal health, sexuality, sociability and metabolic, hematological, renal, and weight loss.

A cardanol based coupling agent is disclosed. The coupling agent is obtained by reacting 3-pentadecyl phenol ethoxylate with sulfur to obtain a sulfurized 3-pentadecyl phenol ethoxylate and reacting the sulfurized 3-pentadecyl phenol ethoxylate with a carbonyl compound. A process for preparing a cardanol based coupling agent is also disclosed. The process comprises reacting 3-pentadecyl phenol ethoxylate with sulfur to obtain a sulfurized 3-pentadecyl phenol ethoxylate and reacting the sulfurized 3-pentadecyl phenol ethoxylate with a carbonyl compound.

Nanocomposites comprising nanoparticles, small molecules, and block copolymer (BCP)-based supramolecules are provided. The nanoparticles, small molecules, and BCP-based supramolecules self-assemble into a plurality of nanosheets that form a multilayer nanocomposite. The nanoparticles, small molecules, and BCP-based supramolecules can be Zr02, 3-pentadecylphenol (PDP), polystyrene-b-poly(4-vinylpyridine) block copolymer (PDP) 1, respectively. b A method of producing a nanocomposite by contacting nanoparticles, small molecules, and BCP-based supramolecules with a solvent and drying to remove the solvent to allow self-assembly is also provided. The nanocomposites provided herein can be used as a barrier material against volatile organic compounds, water, oxygen, or electrons, and can be used as a coating on various substrates and as a packaging material, or as an optical material.

The present application relates to a fragrance composition reproducing the fragrance of white lotus and a skin external composition and a fragrance product containing the fragrance composition reproducing the fragrance of white lotus, and particularly relates to a fragrance composition reproducing the fragrance of white lotus with excellent preference by adding 2-phenylethanol to pentadecane, p-xylene, heptadecane, sabinene, limonene, myrcene, alpha-terpineol, etc. analyzed by SPME method. The fragrance composition provided by the present application contains pentadecane, p-xylene, heptadecane, sabinene, limonene, myrcene, alpha-terpineol, etc. which are main components of the fragrance of white lotus, and also contains 2-phenylethanol, thereby reproducing the fragrance of white lotus and improving the preference of the fragrance.

To provide compounds and compositions for reducing most common opioid-induced hyperalgesia associated with microglial hyperactivation.SOLUTION: 2-pentadecyl-2-oxazoline (PEA-OXA) for use as an opioid adjuvant for preventing the development of or in the treatment of opioid-induced hyperalgesia (OIH), wherein the PEA-OXA is administered with or in combination with an opioid. Wherein the administration is separate, together or simultaneous.SELECTED DRAWING: None

2-Pentadecyl-2-oxazoline (also known as palmitoylethanolamide oxazoline or PEA-OXA) is used to counteract hyperalgesia induced by the most common opioids (OIH) associated with microglial hyperactivation. In particular, PEA-OXA is administered to humans and animals to prevent or treat some of the adverse effects of opioids by controlling immune hyperactivation. The PEA-OXA is administered separately, sequentially or jointly with the opioid.

The present invention relates to the technical field of electrochemistry, relates to the electrochemical synthesis of a muscone precursor, and in particular to a micro-reaction process and system for synthesizing a muscone precursor by means of circulating flow electrolysis. An electrolysis micro-reactor is used to perform a circulating Kolbe electrolysis reaction on a raw material 1 and a raw material 2 in an electrolyte solution to synthesize dimethyl 3-methylpentadecanedioate. During the circulating Kolbe electrolysis reaction, an electrolyzed material discharged from the electrolysis micro-reactor is conveyed to a circulating solution storage tank to discharge a gas generated during electrolysis, and the electrolyzed material from which the gas has been discharged is then conveyed into the electrolysis micro-reactor again for an electrolysis reaction. The present invention shortens an ion conduction distance by means of a micro-channel structure of an electrolysis micro-reactor, promotes, by means of controllable circulating flow of an electrolyte solution, the timely discharge of a gas generated at an electrode, and reduces a cell voltage while the current density is guaranteed. The present invention has the characteristics of low energy consumption, concise process, and easy control.

The invention provides fireproof particles and a preparation method and application thereof, and belongs to the technical field of carbon capture, utilization and storage and the technical field of fireproof materials. The fireproof particle sequentially comprises a composite inner core, a silicon dioxide layer, a super-hydrophobic coating and fins from inside to outside, wherein the composite inner core comprises a mixture of biochar, a mineral material, ammonium polyphosphate and pentacosane; the silicon dioxide layer is located on the surface of the composite core; the super-hydrophobic coating comprises C12-C18 straight chain alkyl trimethoxy silane which is bonded on the surface of the silicon dioxide layer; and the fins are adhered to the surface of the super-hydrophobic coating.

A cardanol based coupling agent is disclosed. The coupling agent is obtained by reacting 3-pentadecyl phenol ethoxylate with sulfur to obtain a sulfurized 3- pentadecyl phenol ethoxylate and reacting the sulfurized 3-pentadecyl phenol ethoxylate with a diisocyanate compound. A process for preparing a cardanol based coupling agent is also disclosed. The process comprises reacting 3-pentadecyl phenol ethoxylate with sulfur to obtain a sulfurized 3-pentadecyl phenol ethoxylate and reacting the sulfurized 3-pentadecyl phenol ethoxylate with a diisocyanate compound.

The present invention discloses a pentadecane parasitic wasp attractant and its application. Compared with existing pest attractants on the market, the pentadecane attractant provided by the present invention attracts beneficial parasitic wasps, eliminating growers' concerns about attracting more pests to their fields. Furthermore, the more beneficial insects there are, the better the field pest control effect. In addition to the pale-footed braconid wasp, the parasitic wasp attractant of the present invention may not only attract parasitic wasps of the Noctuidae family, but also other types of parasitic wasps, thereby increasing the number of parasitic wasps in the field and improving the parasitic wasp parasitism rate in the field, achieving the effect of parasitic wasps controlling field pests.

The invention provides a marine fungus-derived petroleum degrading enzyme, a gene A6006 and application thereof, belongs to the crossing field of biological enzyme technology and environmental remediation, and provides the marine fungus-derived petroleum degrading enzyme, the amino acid sequence of which is shown as SEQ ID NO.2. The gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A6006 of the marine fungus-derived petroleum degrading enzyme can be used for degrading petroleum; the nucleotide sequence of the gene after being optimized by an escherichia coli codon is shown as SEQ ID NO. 1; the marine fungus-derived petroleum degrading enzyme provided by the invention can degrade dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, hexadecanoic acid, naphthalene, phenanthrene and pyrene; and the degradation effect on tetradecane, hexadecane and naphthalene is better.

This disclosure relates to solid forms of (2S)-2-[(10S,17E)-16-ethoxy-6,8,10,12,20-pentamethyl-2,8,10,11,12,13-hexahydro-14H-5,3-(azenometheno)tripyrazolo[3,4-f:3',4'-j:4'',3''-n][1,4]oxazacyclopentadecin-14-yl]propan-1-ol that are useful in the treatment of disease, such as cancer, in mammals. This disclosure also relates to the preparation of such solid forms, including polymorphs, salts, cocrystals, solvates, hydrates, or a combination thereof. This disclosure also relates to compositions including such solid forms, and to methods of using such compositions in the treatment of diseases, such as cancer, in mammals, especially in humans.

The present invention belongs to the field of biotechnology, and particularly relates to Enterococcus italicus for producing fatty alcohols and its applications. Aiming at the problems existing in the production of fatty alcohols by existing microorganisms through fermentation, such as low yield, slow strain improvement, cumbersome detection process, physiological toxicity, and unreasonable selection of metabolic pathways, the present invention provides a strain of Enterococcus italicus for producing fatty alcohols, with the preservation number of CGMCC NO.25136. This strain can simultaneously produce n-heptanol, 1-dodecanol, 1-pentadecanol, 1-hexadecanol, and 1-nonadecanol, providing a strain selection for the preparation of fatty alcohols by microorganisms, and facilitating the research on the synthesis pathway of higher fatty alcohols to improve the ability of engineered bacteria to synthesize fatty alcohols.

The invention belongs to the technical field of energy, and in particular relates to a biological blended fuel which comprises the following components: methyl palmitate, octadecane-9. 12-dienoic acid methyl ester, cis-11-octadecenic acid methyl ester, 2-methyl undecane, 3-methyl undecane, 3, 6-dimethyl decane, 3.7-dimethyl decane, 3, 8-dimethyl-undecane, 3, 8-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, the preparation method comprises the following steps: adding 1, 10-methyl eicosane, 2, 5-dimethyl dodecane, 5-methyl tridecane, 4-methyl-tridecane, 2-bromododecane, 3-methyl-5-propyl nonane, 3-methyl-tetradecane, n-nonane, 6-methyl undecane, 2, 5-dimethyl decane, C16H34, 5-methyl-tetradecane, 7-methyl heptadecane, 4-methyl tetradecane, 3-methyl-tetradecane and 2.5-dimethyl tridecane into a reaction kettle; methyl tetradecane, n-pentadecane and tetradecane; according to the invention, 10-methyleicosane and 5-methyltetradecane are used for providing a high volume calorific value, and the flame temperature is improved compared with that of common biodiesel.

The application provides a synthesis method of dimethyl terephthalate, which comprises the following steps: adding a sulfonic acid catalyst into methanol and terephthalic acid to perform a first esterification reaction to obtain a first esterification product; adding methanol into the first esterification product to perform a second esterification to obtain a second esterification product; adding methanol into the second esterification product to perform crystallization to obtain a crystallization product; and performing distillation on the crystallization product to obtain dimethyl terephthalate; wherein the catalyst comprises one or more than two combinations of hexyl benzene sulfonic acid, dodecyl sulfonic acid, pentadecyl sulfonic acid and dodecyl benzene sulfonic acid. Compared with a traditional concentrated sulfuric acid catalyst, the catalyst used in the application itself, especially after adding an additive, greatly reduces the corrosion of the catalyst to equipment, has good reusability and is more in line with the requirements of green chemistry.

The present invention discloses a bio-based amino polyol brominated epoxy resin, a preparation method, and applications. The bio-based amino polyol brominated epoxy resin has the following structure: wherein R and R1 are both a carbon pentadecanyl group, and R2 is an amino polyol. The polyol of the present invention can be used as a reactive flame retardant in polyurethane foam, which can maximize the mechanical properties of the material; at the same time, the processing technology is simple; and the bio-based amino polyol brominated epoxy resin contains a flame retardant group (Br), which can be used as a polyurethane foam synthetic material and a flame retardant, thereby improving the flame retardant properties of the product. In addition, the amino polyol structure contained in the bio-based amino polyol brominated epoxy resin can completely replace the amino catalyst in the polyurethane foam synthesis, realizing multifunctionality in one.

The subject matter of the present invention is the use of 2-Pentadecyl-2-oxazoline (also known as PEA-OXA) in association with butyric acid, in acidic or salified form, in the treatment of epilepsy and associated psychiatric comorbidities (such as social isolation). In particular, the present invention relates to PEA-OXA for use, in humans and animals, in the prevention and treatment of epileptogenesis and comorbidities associated with epilepsy, such as limited social interaction, wherein PEA-OXA is administered in association or in combination with butyric acid or a salt thereof, wherein said administration is separate, joint, or simultaneous.

Disclosed is a scalable process for preparing 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for preparing the flavor ingredient 3-methylcyclopentadecanone and analogs, by reacting 3-methyl-1,5-cyclopentadecanedione (MCPD) and analogs with metal or metalloid alkoxides in high yield and purity.

According to the degreaser for removing oil on the surfaces of the silver and silver alloy materials and the application, animal and vegetable oil, mineral oil and polishing wax can be emulsified at one time to enable the particle size to be smaller than 100 nm and the emulsification stabilization time to be larger than or equal to 24 h at the temperature of 25-45 DEG C and the oil concentration range of 0.5-5 g / L through gradient HLB cooperation by means of four non-ionic surfactants, the whole system does not contain sulfur, phosphorus and nitrogen heterocyclic rings, the COD contribution is low, and the application range is wide. Discharge can be directly introduced into a conventional biochemical treatment tank, and nonionic compounds only form lt on the surfaces of silver and silver alloy; a weak adsorption layer with the thickness of 3 nm does not interfere with dense deposition of a corrosion inhibition film of a BTA-triethanolamine synergistic corrosion inhibition system, efficient oil removal and no corrosion are ensured, pentadecyl phenol polyoxyethylene ether has solubilizing and conveying effects on BTA, the corrosion inhibitor reaches the metal surface at the microsecond level, the corrosion inhibition efficiency is improved by 20-30%, and the corrosion inhibition effect is good. And triple breakthrough of'efficient oil removal, no corrosion and easy rinsing 'on the surfaces of the silver and the silver alloy is realized, so that the cleaning agent has outstanding creativity in the aspects of materials, formulas and processes.

The present invention provides a method for synthesizing dimethyl terephthalate, comprising: adding a sulfonic acid catalyst into methanol and terephthalic acid, performing a primary esterification reaction, then adding methanol, and performing a secondary esterification reaction; and crystallizing and distilling a secondary esterification product to obtain dimethyl terephthalate, wherein the catalyst comprises hexylbenzenesulfonic acid, dodecyl sulfonic acid, pentadecyl sulfonic acid or dodecylbenzene sulfonic acid. Compared with a concentrated sulfuric acid catalyst, the catalyst used in the present invention greatly weakens the corrosion of the catalyst to a device, and has good repeated use performance.

The present invention belongs to the fields of essence and pharmaceutical engineering, and relates to a preparation method of (-)-muscone and a muscone product. Using 4-methylcyclopentadecanone as a raw material, under the action of sulfur and cyclic secondary amine, (-)-muscone is prepared in one step; wherein, in the system of the one-step reaction, the atmosphere condition is an inert atmosphere condition, the solvent is an aqueous alcohol solution, the reaction temperature is 64 °C to 120 °C, the cyclic secondary amine is a heterocyclic compound, at least one heteroatom of the heterocyclic compound is an N atom, and this N atom is a secondary amine group. The preparation method of the present invention can avoid using chiral reagents to directly prepare a product mainly composed of (-)-muscone.

Tick repellents include one or more of 2-methylisoborneol (2-MIB), D-borneol, L-borneol, and a blend of formic acid, undecane, tridecane, (Z)-4-tridecene, heptadecane, (Z)-9-tricosene, pentadecane, (Z)-9-nonadecene, and (Z)-9-heneicosene; and a carrier material. A method of controlling ticks can include dispensing the tick repellent. Personal care products for topical application can include the tick repellent.

Tick repellents include one or more of 2-methylisoborneol (2-MIB), D-borneol, L-borneol, and a blend of formic acid, undecane, tridecane, (Z)-4-tridecene, heptadecane, (Z)-9-tricosene, pentadecane, (Z)-9-nonadecene, and (Z)-9-heneicosene; and a carrier material. A method of controlling ticks can include dispensing the tick repellent. Personal care products for topical application can include the tick repellent.

The present disclosure provides a dry powder composition of treprostinil prodrugs and a method of treating pulmonary hypertension (e.g., pulmonary arterial hypertension), portopulmonary hypertension, or pulmonary fibrosis in a patient in need thereof. The dry powder composition includes (a) from about 0.1 wt % to about 3 wt % of a compound of Formula (I):or an enantiomer, diastereomer, or a pharmaceutically acceptable salt thereof, (b) from about 0.01 wt % to about 3 wt % of DSPE-PEG2000, (c) from about 10 wt % to about 50 wt % of leucine, and the balance being (d) a sugar selected from the group consisting of trehalose and mannitol. The entirety of (a), (b), (c), and (d) is 100 wt %, and R1 is tetradecyl, pentadecyl, hexadecyl, heptadecyl, or octadecyl. The method includes administering an effective amount of the dry powder composition to the lungs of the patient by inhalation via a dry powder inhaler. In certain compositions and methods provided herein, R1 is hexadecyl, e.g., linear hexadecyl.

The invention provides a marine fungus-derived petroleum degrading enzyme, a gene A5124 and application thereof, belongs to the crossing field of biological enzyme technology and environmental remediation, and provides the marine fungus-derived petroleum degrading enzyme, the amino acid sequence of which is shown as SEQ ID NO.2. The gene A5124 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A5124 of the marine fungus-derived petroleum degrading enzyme has the advantages that the gene A5124 of the marine fungus-derived petroleum degrading enzyme has an amino acid sequence shown as SEQ ID NO.2; the nucleotide sequence of the gene optimized by an escherichia coli codon is as shown in SEQ IN NO. 1; the marine fungus-derived petroleum degrading enzyme provided by the invention can degrade dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, hexadecanoic acid, naphthalene, phenanthrene and pyrene; and the degradation effect on tetradecane, hexadecane, phenanthrene and pyrene is better.

A thermoplastic molding composition comprising at least one thermoplastic polyamide, as com-ponent A; red phosphorous, as component B; at least one fibrous and / or particulate filler, as component C; and wherein component A comprises at least one polyamide of A1) units derived from 1, 5-pentanediamine as component A1; A2) units derived from at least one aliphatic dicarboxylic acid, preferably selected from the group consisting of adipic acid, succinic acid, glutaric acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, undecanedioic acid, dodecanedioic acid, tridecanedioic acid, tetradecanedioic acid, pentadecanedioic acid, hexadecanedioic acid, heptadecanedioic acid, and octadecanedioic acid, as component A2; A3) units derived from at least one aromatic dicarboxylic acid, preferably selected from the group consisting of terephthalic acid, isophthalic acid, and phthalic acid, as component A3; wherein the molar ratio of component A1 to the sum of components A2 and A3 is 1-1.05 to 0.95; a process for preparing of the inventive thermoplastic molding composition; the use of the in-ventive thermoplastic molding composition for producing fibers, foils or moldings; and fibers, foils or moldings comprising the inventive thermoplastic molding composition.

The present disclosure provides methods for treating pulmonary hypertension (PH) in a patient in need thereof, comprising administering via a dry powder inhaler (DPI) to the patient, during an administration period, a compound of Formula (I), (I), or an enantiomer, diastereomer, or a pharmaceutically acceptable salt thereof, wherein R1 is tetradecyl, pentadecyl, hexadecyl, heptadecyl, or octadecyl. In embodiments, during the administration period, the compound of Formula (I), or an enantiomer, diastereomer, or a pharmaceutically acceptable salt thereof, is administered at a starting dose comprising about 80 μg to 160 μg once daily in a single dosing session, and the starting dose is titrated during the titration period to a maximum tolerated dose (MTD) of about 1280 µg or less. In embodiments, the administration period comprises a maintenance period, and the MTD is administered to the patient during the maintenance period. In embodiments, during the administration period, a dose of about 700-1300 µg of the compound of Formula (I), or enantiomer, diastereomer, or a pharmaceutically acceptable salt thereof, is administered once daily in a single dosing session to the patient.

The invention provides a method for detecting an AKD (Alkyl Ketene Dimer) sizing agent in paper, which comprises the following steps: sequentially carrying out pretreatment including hydrolysis treatment and extraction treatment on a to-be-detected paper sample to obtain a to-be-detected liquid; determining the to-be-detected liquid by adopting a gas chromatography-mass spectrometry method, and determining whether the to-be-detected liquid contains the AKD sizing agent hydrolysate or not according to the retention time of a gas chromatography peak in a determination result and the ratio of the ion strength of daughter ions to parent ions of a mass spectrum, the hydrolysis product of the AKD sizing agent comprises 16-trihenone, 16-tridecanone and 18-pentacosanone. The invention further discloses a preparation method of the AKD sizing agent. The detection method provided by the invention fills the blank of detection of the AKD sizing agent in the paper in the identification field, and provides a more accurate physical evidence identification direction for identification through qualitative and quantitative detection of the AKD sizing agent in the paper.

The invention belongs to the technical field of synthesis and separation of coalification products, and particularly relates to a method for separating phenol monomers from industrial xylenol. The method for separating the phenol monomer from the industrial xylenol comprises the following steps: mixing the industrial xylenol, 6-(1-methyl-pentadecyl)-2, 4-xylenol, hexadecene and sulfuric acid for a first reaction, after the reaction is finished, adjusting the pH value of a reaction solution to 7-8, washing with water, removing a water layer, and carrying out rectification treatment on a material layer. The method for separating the phenol monomer from the industrial xylenol has the beneficial effects that the hexadecene can react with the 2, 4-xylenol in the industrial xylenol under a certain condition to generate an antioxidant 6-(1-methyl-pentadecyl)-2, 4-xylenol, and the 2, 5-xylenol does not react with the hexadecene, so that the antioxidant 6-(1-methyl-pentadecyl)-2, 4-xylenol does not react with the hexadecene; the method comprises the following steps of: separating 2, 4, 5-xylenol and 1-methyl-pentadecyl-methyl-2, 4-xylenol, and rectifying and separating to obtain pure 6-(1-methyl-pentadecyl)-2, 4-xylenol and 99% 2, 5-xylenol, so that the separation of 2, 4 / 2, 5-xylenol is realized, and an efficient polymerization inhibitor 6-(1-methyl-pentadecyl)-2, 4-xylenol is produced as a byproduct.