102 results about "Farnesene" patented technology

The invention discloses production of terpenoids and a strain, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing linalool, isoprene, isopentenol, 1, 3, 4-triterpenes and 1, 3, 4-triterpenes. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 40.72 g.L <-1 >.

The invention relates to the technical field of biology, in particular to a recombinant strain for producing beta-farnesene as well as a construction method and application of the recombinant strain. According to the present invention, the beta-farnesene synthase MacbFS variant gene derived from chamomile is integrated to four sites such as YPRCDelta 15, YML059C, YDR448W and YIL009C, or is integrated to four sites such as YPRCDelta 15, YML059C, YBR128C and YHR178W, such that the recombinant strain with the high yield of beta-farnesene is obtained; experiments show that the combination of the sites has better heterologous gene expression potential, the yield of the beta-farnesene is obviously increased, the shake flask yield is up to 882.88-1054.10 mg / L, and a new way is provided for biosynthesis of the beta-farnesene.

The invention belongs to the technical field of bioengineering, and particularly relates to an application of EcorOBP7 in combination with odor information molecules, and the nucleotide sequence of the EcorOBP7 is as shown in SEQ ID NO.1; the odor information molecules comprise at least one of (E)-beta-farnesene, (E)-beta-myrcene, 3-methylbutyraldehyde, (Z)-beta-ocimene, linalool and cis-acetamino acetate. The odor information molecules are used for detecting the odor of the odor information molecules, and the odor information molecules comprise at least one of (E)-beta-farnesene and (E)-beta-myrcene. The invention finds that EcorOBP7 is a broad-spectrum binding protein, can interact with various information molecules, and can be strongly bound with substances such as (E)-beta-farnesene and cis-acetamido acetate, so that EcorOBP7 can sense odor molecules in the environment through EcorOBP7 highly expressed on antennas of EcorOBP7. Female insects can find proper hosts and spawning sites by distinguishing volatile substances of plants, male insects can find the female insects for mating through perceptual pheromones, and it is indicated that the protein can adjust the foraging and spawning behaviors of eutrophus maculans.

The invention provides a farnesene composite polymerization inhibitor and a use method thereof, and the farnesene composite polymerization inhibitor comprises five components: a quinone methyl compound, a phenolic compound, substituted 2, 2, 6, 6-tetramethylpiperidine-1-oxygen free radical, citric acid and a solvent isopropyl myristate. Wherein the retarder is a quinone methyl compound and a phenolic compound, the true polymerization inhibitor is substituted 2, 2, 6, 6-tetramethylpiperidine-1-oxygen free radical, the synergist is citric acid, the solvent is isopropyl myristate, the quinone methyl compound is small in toxicity, the synergist is low in price, and the environmental protection property and economical efficiency of the polymerization inhibitor can be effectively improved. According to the invention, the induction period of the polymerization inhibitor can be effectively prolonged, farnesene oxides and dimers are reduced, the formation of high polymers is blocked, the rectification yield of farnesene is improved, and the polymerization inhibitor has good polymerization inhibition and environmental protection properties. The composite polymerization inhibitor provided by the invention is used in the rectification process of farnesene, and can be popularized to the transportation, storage and use processes of farnesene so as to improve the purity of farnesene.

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention discloses a method for producing terpenoids, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing isoprene, isopentenol, 1, 3, 4-triterpenes, 1, 3, 4-triterpenes and the like. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 13.49 g.L <-1 >.

The invention belongs to the technical field of biological medicine, and particularly relates to lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center (CGMCC); the preservation number is CGMCC No. 32360; the preservation date is October 25, 2024; the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. Compared with commercial Acetobacter pasteurianus, the apricot vinegar prepared from the lactobacillus paracasei ZY101 has the advantages that newly added substances comprise linalool, alpha-farnesene, ethyl 2-phenylacetate and geranyl geraniol; the fragrance of the apricot vinegar is further promoted. Compared with commercial Acetobacter pasteurianus, the content of the existing substances is obviously increased, and the existing substances specifically comprise ethyl acetate, isoamyl acetate, ethyl caprylate, ethyl hexanoate, acetoin, methyl palmitate, gamma-decalactone, ethyl laurate, delta-decalactone, trans-nerol and dihydro-beta-ionone.

The invention relates to a thickening composition intended for topical application on the skin, lips or skin appendages, said thickening composition comprising at least one oil derived from a biological source and at least one poly(farnesene) polymer having a number average molar mass ranging from 10,000 to 120,000 g / mol. The invention also relates to a cosmetic composition comprising the thickening composition according to the invention and the use of the thickening composition according to the invention in a cosmetic composition.

The invention discloses a genetically engineered bacterium and an application of the genetically engineered bacterium in production of farnesene. The genetically engineered bacterium takes saccharomyces cerevisiae as a chassis strain; an exogenous beta-farnesene synthase gene is integrated, an ERG9 gene is knocked out, a promoter of a truncated HMG1 gene is replaced with an ANB1 promoter, an exogenous transhydrogenase gene is integrated and driven by a glucose sensitive promoter, beta-farnesene synthase is mutated and fused with a transmembrane structural domain of ABC transporter protein PDR10, and then a chimeric expression unit is constructed. According to the present invention, the chassis bacteria are modified by at least one of the steps of overexpression of phosphatidylcholine synthetase, knockout of sterol ester synthetase and introduction of exogenous alkyl glycerol monooxygenase, and the obtained engineering bacteria are combined with the optimized fermentation process so as to significantly improve the farnesene synthesis efficiency and the production economy; therefore, the genetically engineered bacterium and the fermentation method provided by the invention have good application prospects.

Provided are: a hot-melt adhesive composition which contains a large amount of plant-derived components, has excellent adhesive properties, in particular, 180 DEG peel adhesion, constant load retention, and shear retention, and also has high re-peelability; and an adhesive tape which has an adhesive layer that contains the adhesive composition. The hot melt adhesive composition contains at least (A) a styrene block copolymer having a farnesene structure, (B) a thermoplastic resin having a kinematic viscosity (40 DEG C) of 150 mm2 / s to 200 thousand mm2 / s or a number average molecular weight (Mn) of 450 to 4000, and (C) a tackifier resin having a softening point of 100 DEG C or more. The tackifying resin (C) is contained in an amount of 30 to 500 parts by mass per 100 parts by mass of the styrene block copolymer (A).

The invention relates to the use of a composition (C) comprising, for 100% of the weight thereof,—from 10% by weight to 90% by weight of at least one poly(farnesene) polymer having a number-average molecular weight of greater than or equal to 10,000 g / mol and less than or equal to 120,000 g / mol, said poly(farnesene) polymer being partially or totally hydrogenated and / or functionalized with hydroxyl radicals, and—from 10% by weight to 90% by weight of a mixture (M) of hydrocarbons in which at last 94% by weight of said hydrocarbons comprise from 15 to 19 carbon atoms, for preventing and / or slowing the appearance of unattractive effects on human hair following exposure to intense heat. The invention also relates to a method for drying and shaping the hair, using said composition.

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

Described herein is a method for making intermediates in the production of fragrance components starting from β-farnesene via a mixture comprising an epoxide represented by formula (III) as defined herein and an epoxide represented by formula (IV). In particular, methods for making acetylmethyl farnesol and hydroxyfarnesyl acetone and their homologues are described.

Disclosed are: a hydrogenated product of a block copolymer having a low glass transition temperature and exhibiting good flexibility, rubber elasticity, and elongation property even in a low temperature region; a resin composition; and a method for producing the hydrogenated product of the block copolymer, in which the hydrogenated product of the block copolymer contains a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing a structural unit derived from a conjugated diene compound, and satisfies the following conditions (1) to (3): (1) the structural unit derived from the conjugated diene compound in the polymer block (B) has a structural unit derived from butadiene and a structural unit derived from isoprene, but does not have a structural unit derived from farnesene; (2) the hydrogenated product of the block copolymer has a glass transition temperature of -50°C or lower; and (3) when a weight average molecular weight of the hydrogenated product of the block copolymer is defined as x and a crystallization temperature of the hydrogenated product of the block copolymer is defined as y (°C), 5.8x / 100,000 - y > 17 is satisfied.

The present invention provides a process for preparing a 2-(3-alkenyl)-1,3-butadiene compound of the following general formula (A), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), the process comprising the step of subjecting a secondary allylsulfone compound of the following general formula (G), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), W represents an arenesulfonyl group, and Z represents a halogen atom, to a reductive removal of an arenesulfonyl group, W, at an allyl position, and then subjecting the secondary allylsulfone compound (G) to an elimination reaction of a hydrogen halide, HZ, in this order or in reverse order, to form the 2-(3-alkenyl)-1,3-butadiene compound (A).

The invention discloses a recombinant strain for producing farnesene as well as a construction method and application thereof. The construction method comprises the following steps: preparing a pFII plasmid containing farnesene synthase, farnesyl pyrophosphate synthase and isopentene diphosphate isomerase; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing the primer 1 and the primer 2 to obtain a fragment 1; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing a primer 3 and a primer 4 to obtain a fragment 2; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing a primer 5 and a primer 6 to obtain a fragment 3; carrying out seamless connection on the fragment 1, the fragment 2 and the fragment 3 to obtain a plasmid 1; introducing a plasmid 1, a plasmid 2 and a plasmid 3 into escherichia coli to obtain a recombinant strain for producing farnesene; the farnesene yield of the recombinant strain 1 constructed by the invention is 3.3 g / L within 96 hours, and technical support and data reference are provided for large-scale preparation of biological fuel farnesene by a biological method.

A method for the industrial production of teprenone and its application. The present invention belongs to the field of teprenone synthesis. The purpose of the present invention is to solve the technical problems of the existing teprenone synthesis method, which has a long route, many side reactions, and requires the use of special reagents. The method of the present invention comprises the following steps: first, farnesene is reacted with acetoacetate in the presence of a catalyst to obtain farnesene ketone ester, which is then decarboxylated to produce farnesene acetone, and then subjected to a reduction reaction, a halogenation reaction, and a Wittig reaction to obtain teprenone. The method avoids the shortcomings of existing processes, has fewer conversion steps in the synthesis route, and produces teprenone with high yield and purity, making it suitable for industrial production. The teprenone of the present invention is used as a drug for treating gastric diseases.

The invention relates to the field of genetic engineering and bioengineering, in particular to engineering algae capable of synthesizing alpha-farnesene and a preparation method of the engineering algae. An MEP metabolic network of synechocystis PCC 6803 is modified, through single-copy series recombination and multi-copy combination of dxs, ispA, idi and AFS genes, optimization of a farnesene MEP metabolic pathway is achieved, the carbon flux of oriented synthesis of farnesene is precisely regulated and controlled, under the optimal effect, the yield of alpha-farnesene within 9 days is 83.07 mg / L (25.82 mg / g DCW), and economic application value is achieved.

To provide a method for producing polymer fine particles which can provide a resin composition that is excellent in controllability of an internal temperature and an internal pressure in an elastic body polymerization step, and is excellent in flowability.SOLUTION: A method for producing polymer fine particles includes an elastic body polymerization step of polymerizing a monomer A containing farnesene and thereby obtaining an elastic body having a volume average particle diameter of less than 50 nm, and a graft part polymerization step, wherein in the elastic body polymerization step, increase per one hour in a polymerization conversion rate of the monomer A is 20.0 (% / hour) or less.SELECTED DRAWING: None

Provided are: a hydrogenated block copolymer which has a low glass transition temperature and exhibits good flexibility, rubber elasticity and elongation characteristics even in a low-temperature region; a resin composition; a method for producing the hydrogenated block copolymer; and a hydrogenated block copolymer which contains a polymer block (A) and a polymer block (B), the polymer block (A) contains a structural unit derived from an aromatic vinyl compound, the polymer block (B) contains a structural unit derived from a conjugated diene compound, and the hydrogenated product of the block copolymer satisfies the following conditions (1)-(3). (1) The constituent units derived from the conjugated diene compound in the polymer block (B) have a constituent unit derived from butadiene and a constituent unit derived from isoprene, but do not have a constituent unit derived from farnesene. (2) The glass transition temperature of the hydrogenated product of the block copolymer is-50 DEG C or less. (3) the relationship of 5.8 x / 100,000-ygt is satisfied, where x is the weight-average molecular weight of the hydrogenated product of the block copolymer and y (DEG C) is the crystallization temperature of the hydrogenated product of the block copolymer; 17).

The application provides application of farnesene in prevention and treatment of southern root-knot nematode, belongs to the technical field of prevention and treatment of root-knot nematode, and the concentration of farnesene in prevention and treatment of southern root-knot nematode is 92-118 ng / h per plant. The application finds that farnesene exposure treatment can effectively inhibit the invasion and reproduction of southern root-knot nematode and significantly reduce the feeding preference of southern root-knot nematode to corn by using farnesene to expose and treat corn plants, and farnesene can improve the resistance of plants by regulating and improving the content of defense hormone jasmonic acid isoleucine complex in corn. In conclusion, the application provides a new idea for green prevention and control of southern root-knot nematode.

A resin composition containing an ethylene-vinyl acetate copolymer (I) and a hydrogenated block copolymer (II), wherein the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) containing a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, wherein the hydrogenation rate of carbon-carbon double bonds in the structural unit derived from a conjugated diene in the block copolymer (P) is 70 mol % or more, and in the resin composition, the content of the ethylene-vinyl acetate copolymer (I) is 40 to 95% by mass and the content of the hydrogenated block copolymer (II) is 5 to 60% by mass.

The present invention relates to the use of a composition (C) for preventing and / or slowing the appearance of an unpleasant effect of human hair after exposure to strong heat, said composition (C) comprising, for 100% by weight thereof:-from 10% to 90% by weight of at least one poly (farnesene) polymer having a number average molecular weight greater than or equal to 10,000 g / mol and less than or equal to 120,000 g / mol, said poly (farnesene) polymer is partially or wholly hydrogenated and / or functionalized with hydroxyl groups, and-10% to 90% by weight of a mixture (M) of hydrocarbons wherein at least 94% by weight of said hydrocarbons comprise 15 to 19 carbon atoms. The invention also relates to a method for drying and shaping hair using the above composition.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The invention discloses a construction method and application of alpha-farnesene-producing pichia pastoris, and belongs to the technical field of biology. The invention discloses a novel pichia pastoris engineering strain which has the capability of efficiently synthesizing alpha-farnesene. According to the strain, through metabolic pathway optimization and key enzyme high expression, the carbon flow distribution efficiency of a substrate to alpha-farnesene is remarkably improved. The yield of an excellent strain pichia pastoris mut008 obtained through ARTP mutagenesis and multiple rounds of screening reaches 3.05 g / L under the level of a 5L fermentation tank when methanol is used as a substrate, and the yield preliminarily reaches the level required by industrial production of C1 substrate utilization; when glucose is used as a substrate, the yield reaches 30.66 g / L, and the industrial production cost can be reduced.

A thermoplastic elastomer composition including an acrylic block copolymer (I) and a hydrogenated block copolymer (II). The content of the acrylic block copolymer (I) is 70 to 300 parts by mass with respect to 100 parts by mass of the hydrogenated block copolymer (II); the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) including a polymer block (A1) containing structural units derived from an aromatic vinyl compound, and a polymer block (B1) containing 1 to 100 mass % of structural units (b1) derived from farnesene and 99 to 0 mass % of structural units (b2) derived from a conjugated diene other than farnesene, the mass ratio [(A1) / (B1)] of the polymer block (A1) to the polymer block (B1) being 1 / 99 to 70 / 30; and the hydrogenation ratio of carbon-carbon double bonds in the polymer block (B1) is 50 to 100 mol %.

To provide an active energy ray-curable composition which has a low viscosity and is capable of yielding a cured product having excellent transparency as well as excellent flexibility and heat resistance; a cured product thereof; and a layered product.SOLUTION: An active energy ray-curable composition contains: a urethane (meth)acrylate (X) having a structural unit derived from farnesene; a (meth)acrylate (Y) other than the urethane (meth)acrylate (X); and a photopolymerization initiator (Z). Also provided are: a cured product of the active energy ray-curable composition; and a layered product that comprises a layer containing at least one of the active energy ray-curable composition and the cured product, and two or more transparent base materials.SELECTED DRAWING: None

To provide a resin composition that enables superior thermal and melt adhesion to a resin having a polar group and allows development of sufficient tensile fracture strain.SOLUTION: A resin composition comprises (A) a hydrogenated product of a block copolymer of an aromatic vinyl compound and a conjugated diene compound, (B) a polyester elastomer, (C) a crystalline polyester, and (D) an ethylene-unsaturated carboxylic acid copolymer, the resin composition optionally further containing (E) a non-aromatic rubber softener. The component (A) may have structural units derived from β-farnesene. The component (B) may include a polybutylene terephthalate-based elastomer.SELECTED DRAWING: Figure 1

Heat transfer compositions, and systems and methods using the composition, comprising: (a) a refrigerant comprising at least about 30% by weight based on all refrigerant components of trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)); and at least one compound inhibiting isomerization of said trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)) to cis-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(Z)), said at least one compound being selected from the group consisting of d-limonene, 2,6-diisopropyl naphthalene, β-pinene, farnesene, α-terpinene and combinations of two or more of these.

Described herein is an invention that includes a spreadable conditioning composition comprising a blend of: a branched hydrocarbon and an ester having a kinematic viscosity of less than or equal to about 100 centistokes. The composition may be natural, for example, if each of the branched hydrocarbon and the ester are independently vegetable-derived. In addition, the composition may lack ingredients that are derived from a palm oil. In an embodiment, the composition is a blend of hydrogenated farnesene and an ester selected from glyceryl triheptanoate, heptyl undecylenate, and mixtures thereof. The composition exhibits an average spreading velocity of about 4 to about 8. Also disclosed are formulations for use in products of personal care, home / institutional care, industry, pharmaceutical and medical and veterinary care and related methods.