52 results about "Farnesene" patented technology

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention discloses a genetically engineered bacterium and an application of the genetically engineered bacterium in production of farnesene. The genetically engineered bacterium takes saccharomyces cerevisiae as a chassis strain; an exogenous beta-farnesene synthase gene is integrated, an ERG9 gene is knocked out, a promoter of a truncated HMG1 gene is replaced with an ANB1 promoter, an exogenous transhydrogenase gene is integrated and driven by a glucose sensitive promoter, beta-farnesene synthase is mutated and fused with a transmembrane structural domain of ABC transporter protein PDR10, and then a chimeric expression unit is constructed. According to the present invention, the chassis bacteria are modified by at least one of the steps of overexpression of phosphatidylcholine synthetase, knockout of sterol ester synthetase and introduction of exogenous alkyl glycerol monooxygenase, and the obtained engineering bacteria are combined with the optimized fermentation process so as to significantly improve the farnesene synthesis efficiency and the production economy; therefore, the genetically engineered bacterium and the fermentation method provided by the invention have good application prospects.

Provided are: a hot-melt adhesive composition which contains a large amount of plant-derived components, has excellent adhesive properties, in particular, 180 DEG peel adhesion, constant load retention, and shear retention, and also has high re-peelability; and an adhesive tape which has an adhesive layer that contains the adhesive composition. The hot melt adhesive composition contains at least (A) a styrene block copolymer having a farnesene structure, (B) a thermoplastic resin having a kinematic viscosity (40 DEG C) of 150 mm2 / s to 200 thousand mm2 / s or a number average molecular weight (Mn) of 450 to 4000, and (C) a tackifier resin having a softening point of 100 DEG C or more. The tackifying resin (C) is contained in an amount of 30 to 500 parts by mass per 100 parts by mass of the styrene block copolymer (A).

The invention relates to the use of a composition (C) comprising, for 100% of the weight thereof,—from 10% by weight to 90% by weight of at least one poly(farnesene) polymer having a number-average molecular weight of greater than or equal to 10,000 g / mol and less than or equal to 120,000 g / mol, said poly(farnesene) polymer being partially or totally hydrogenated and / or functionalized with hydroxyl radicals, and—from 10% by weight to 90% by weight of a mixture (M) of hydrocarbons in which at last 94% by weight of said hydrocarbons comprise from 15 to 19 carbon atoms, for preventing and / or slowing the appearance of unattractive effects on human hair following exposure to intense heat. The invention also relates to a method for drying and shaping the hair, using said composition.

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

Described herein is a method for making intermediates in the production of fragrance components starting from β-farnesene via a mixture comprising an epoxide represented by formula (III) as defined herein and an epoxide represented by formula (IV). In particular, methods for making acetylmethyl farnesol and hydroxyfarnesyl acetone and their homologues are described.

The present invention provides a process for preparing a 2-(3-alkenyl)-1,3-butadiene compound of the following general formula (A), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), the process comprising the step of subjecting a secondary allylsulfone compound of the following general formula (G), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), W represents an arenesulfonyl group, and Z represents a halogen atom, to a reductive removal of an arenesulfonyl group, W, at an allyl position, and then subjecting the secondary allylsulfone compound (G) to an elimination reaction of a hydrogen halide, HZ, in this order or in reverse order, to form the 2-(3-alkenyl)-1,3-butadiene compound (A).

A method for the industrial production of teprenone and its application. The present invention belongs to the field of teprenone synthesis. The purpose of the present invention is to solve the technical problems of the existing teprenone synthesis method, which has a long route, many side reactions, and requires the use of special reagents. The method of the present invention comprises the following steps: first, farnesene is reacted with acetoacetate in the presence of a catalyst to obtain farnesene ketone ester, which is then decarboxylated to produce farnesene acetone, and then subjected to a reduction reaction, a halogenation reaction, and a Wittig reaction to obtain teprenone. The method avoids the shortcomings of existing processes, has fewer conversion steps in the synthesis route, and produces teprenone with high yield and purity, making it suitable for industrial production. The teprenone of the present invention is used as a drug for treating gastric diseases.

The invention relates to the field of genetic engineering and bioengineering, in particular to engineering algae capable of synthesizing alpha-farnesene and a preparation method of the engineering algae. An MEP metabolic network of synechocystis PCC 6803 is modified, through single-copy series recombination and multi-copy combination of dxs, ispA, idi and AFS genes, optimization of a farnesene MEP metabolic pathway is achieved, the carbon flux of oriented synthesis of farnesene is precisely regulated and controlled, under the optimal effect, the yield of alpha-farnesene within 9 days is 83.07 mg / L (25.82 mg / g DCW), and economic application value is achieved.

The application provides application of farnesene in prevention and treatment of southern root-knot nematode, belongs to the technical field of prevention and treatment of root-knot nematode, and the concentration of farnesene in prevention and treatment of southern root-knot nematode is 92-118 ng / h per plant. The application finds that farnesene exposure treatment can effectively inhibit the invasion and reproduction of southern root-knot nematode and significantly reduce the feeding preference of southern root-knot nematode to corn by using farnesene to expose and treat corn plants, and farnesene can improve the resistance of plants by regulating and improving the content of defense hormone jasmonic acid isoleucine complex in corn. In conclusion, the application provides a new idea for green prevention and control of southern root-knot nematode.

A resin composition containing an ethylene-vinyl acetate copolymer (I) and a hydrogenated block copolymer (II), wherein the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) containing a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, wherein the hydrogenation rate of carbon-carbon double bonds in the structural unit derived from a conjugated diene in the block copolymer (P) is 70 mol % or more, and in the resin composition, the content of the ethylene-vinyl acetate copolymer (I) is 40 to 95% by mass and the content of the hydrogenated block copolymer (II) is 5 to 60% by mass.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The invention discloses a construction method and application of alpha-farnesene-producing pichia pastoris, and belongs to the technical field of biology. The invention discloses a novel pichia pastoris engineering strain which has the capability of efficiently synthesizing alpha-farnesene. According to the strain, through metabolic pathway optimization and key enzyme high expression, the carbon flow distribution efficiency of a substrate to alpha-farnesene is remarkably improved. The yield of an excellent strain pichia pastoris mut008 obtained through ARTP mutagenesis and multiple rounds of screening reaches 3.05 g / L under the level of a 5L fermentation tank when methanol is used as a substrate, and the yield preliminarily reaches the level required by industrial production of C1 substrate utilization; when glucose is used as a substrate, the yield reaches 30.66 g / L, and the industrial production cost can be reduced.

A thermoplastic elastomer composition including an acrylic block copolymer (I) and a hydrogenated block copolymer (II). The content of the acrylic block copolymer (I) is 70 to 300 parts by mass with respect to 100 parts by mass of the hydrogenated block copolymer (II); the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) including a polymer block (A1) containing structural units derived from an aromatic vinyl compound, and a polymer block (B1) containing 1 to 100 mass % of structural units (b1) derived from farnesene and 99 to 0 mass % of structural units (b2) derived from a conjugated diene other than farnesene, the mass ratio [(A1) / (B1)] of the polymer block (A1) to the polymer block (B1) being 1 / 99 to 70 / 30; and the hydrogenation ratio of carbon-carbon double bonds in the polymer block (B1) is 50 to 100 mol %.

To provide a resin composition that enables superior thermal and melt adhesion to a resin having a polar group and allows development of sufficient tensile fracture strain.SOLUTION: A resin composition comprises (A) a hydrogenated product of a block copolymer of an aromatic vinyl compound and a conjugated diene compound, (B) a polyester elastomer, (C) a crystalline polyester, and (D) an ethylene-unsaturated carboxylic acid copolymer, the resin composition optionally further containing (E) a non-aromatic rubber softener. The component (A) may have structural units derived from β-farnesene. The component (B) may include a polybutylene terephthalate-based elastomer.SELECTED DRAWING: Figure 1

Heat transfer compositions, and systems and methods using the composition, comprising: (a) a refrigerant comprising at least about 30% by weight based on all refrigerant components of trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)); and at least one compound inhibiting isomerization of said trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)) to cis-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(Z)), said at least one compound being selected from the group consisting of d-limonene, 2,6-diisopropyl naphthalene, β-pinene, farnesene, α-terpinene and combinations of two or more of these.

Described herein is an invention that includes a spreadable conditioning composition comprising a blend of: a branched hydrocarbon and an ester having a kinematic viscosity of less than or equal to about 100 centistokes. The composition may be natural, for example, if each of the branched hydrocarbon and the ester are independently vegetable-derived. In addition, the composition may lack ingredients that are derived from a palm oil. In an embodiment, the composition is a blend of hydrogenated farnesene and an ester selected from glyceryl triheptanoate, heptyl undecylenate, and mixtures thereof. The composition exhibits an average spreading velocity of about 4 to about 8. Also disclosed are formulations for use in products of personal care, home / institutional care, industry, pharmaceutical and medical and veterinary care and related methods.

The invention relates to the technical field of genetic engineering, in particular to an engineering bacterium for producing beta-farnesene and application of the engineering bacterium. According to the invention, different advantage modification strategies are matched for the existing engineering strain for producing the beta-farnesene, the YPL062W knockout chassis modification strategy is applied to the biosynthesis of the beta-farnesene for the first time, and the production capacity of the beta-farnesene is greatly improved in combination with ERG9 down-regulation.

There is provided a method for the selective epoxidation of farnesene using a catalyst comprising a metal M complexed with a salen ligand of formula (I).

By using as a polyol component and as a copolymer component of poly(farnesene) diol and ε-caprolactone, a polyurethane composition and method having mechanical properties comparable to the most performance-commercial elastomeric materials are described. The poly(farnesene) diol is produced from biobased monomers, and such copolymerization enables the incorporation of renewable materials into high-performance polyurethane materials.

The present invention relates to a composition comprising sinensal and sinensol, and to the use thereof as an aroma chemical. The invention relates moreover to the use of sinensol to enhance the persistence or to modify the aroma of sinensal or of a mixture of sinensal and farnesene.

This invention relates to the terpene synthase AaTPS48 from Artemisia argyi, its encoding gene, and its applications. It provides an important foundation for utilizing genetic engineering techniques to increase the content of the active components myrcene and (trans)-β-farnesene in Artemisia argyi, or to directly produce myrcene and (trans)-β-farnesene. The technical solution is that the terpene synthase AaTPS48 is a protein of the following a) or b) or c): a) the amino acid sequence of the protein shown in SEQ ID No. 1; b) a fusion protein obtained by attaching a tag to the N-terminus and / or C-terminus of the protein shown in SEQ ID No. 1; c) a protein with the same function obtained by substituting and / or deleting and / or adding one or more amino acid residues of the amino acid sequence shown in SEQ ID No. 1. The AaTPS48 protein of this invention can catalyze both GPP to form myrcene and FPP to form (trans)-β-farnesene, playing an important role in the biosynthesis of myrcene, (trans)-β-farnesene, and other terpene compounds in Artemisia argyi.

The invention belongs to the technical field of microbial fermentation. The invention relates to saccharomyces cerevisiae, in particular to saccharomyces cerevisiae with high yield of farnesene and squalene and application of the saccharomyces cerevisiae. The yeast-like yeast is constructed by the following steps: providing yeast-like host bacteria; an exogenous farnesene synthase coding gene is introduced into the yeast-like host bacteria, so that the farnesene synthase coding gene is expressed in a host; transforming a genome of the yeast-like host bacterium so as to improve the expression activity of endogenous squalene synthase of the yeast-like host bacterium; strengthening the mevalonic acid pathway of the yeast-like host bacteria; and screening to obtain an engineering strain capable of simultaneously accumulating farnesene and squalene, thereby obtaining the saccharomyces-like strain capable of producing farnesene and squalene at high yield. The genetic stability of the saccharomyces cerevisiae meets the condition that more than 90% of farnesene and squalene producing capacity is still maintained after continuous passage for 50 generations in a culture medium without selective pressure.

The application provides a beta-farnesene synthetase mutant and application thereof, and belongs to the technical field of protein engineering modification and engineering bacteria. The application firstly performs semi-rational design on beta-farnesene synthetase AanFS by using protein engineering, adopts homologous modeling, uses molecular docking and molecular dynamics simulation, and calculates a mutant beneficial to improve the activity, obtains multiple active sites with improved activity after experimental verification, combines mutation, and obtains the optimal mutant AanFS K197T / F180H The yield of beta-farnesene is increased by 283.8% compared with the wild type. Meanwhile, a Yarrowia lipolytica strain Q26 strain expressing the beta-farnesene synthetase mutant is obtained by using genetic engineering technology, the strain can utilize oleic acid and kitchen waste oil as carbon sources to produce beta-farnesene, is an excellent strain for high-yield beta-farnesene, and therefore has good practical application value.

A resin composition and a molded article thereof, the resin composition containing a rubber (I), a block copolymer (II), and a crosslinking agent (III), the mass ratio [(I) / (II)] of the aforementioned rubber (I) to the aforementioned block copolymer (II) being from 99 / 1 to 55 / 45, the aforementioned block copolymer (II) being a block copolymer containing a polymer block (A) and a polymer block (B), the polymer block (A) containing a structural unit derived from an aromatic vinyl compound, and the polymer block (B) containing a structural unit (b1) derived from farnesene.

There is provided a method for improving glucose, xylose and arabinose utilization in Saccharomyces cerevisiae, the method comprising the steps of: using Saccharomyces cerevisiae having the ability to convert xylose and / or arabinose to ethanol, lactic acid, succinic acid, farnesene or isobutanol as a chassis cell, the saccharomyces cerevisiae gene is modified in the following mode in a genome: A, mutation in a TRK1 gene of a potassium ion intracellular transporter causes increase of a potassium ion / sodium ion ratio in a saccharomyces cerevisiae cell, and / or B, mutation in a PUF2 gene of mRNA binding protein or knockout of the PUF2 gene causes deactivation, deletion, function reduction or mRNA translation intensity reduction of the PUF2. The constructed recombinant saccharomyces cerevisiae can produce ethanol, lactic acid, succinic acid, farnesene or isobutanol through fermentation by utilizing cellulase hydrolysate containing glucose, xylose and / or arabinose, and has a wide application prospect.

It is provided an adhesive composition having a high biobased content and having a moderate adhesive property and high heat resistance and a method for producing the same, and an adhesive composition including: a block copolymer (X) including a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing a structural unit derived from a conjugated diene compound, and a tackifier (Y), in which the block copolymer (X) includes, as the polymer block (B), at least one polymer block (B-1) containing a structural unit derived from β-farnesene, and the block copolymer (X) include at least one selected from the group consisting of an unhydrogenated block copolymer (X0) which is a block copolymer that is not hydrogenated, and a hydrogenated block copolymer (X1) which is a hydrogenated block copolymer and has a degree of hydrogenation of less than 50 mol %.

The invention provides a tick repellent as well as a preparation method and application thereof. The tick repellent provided by the invention contains the linalool, the (E)-beta-farnesene and the 4-terpene alcohol, and the linalool, the (E)-beta-farnesene and the 4-terpene alcohol are subjected to compounding proportion exploration; the tick repelling effect of the finally compounded tick repellent containing various compounds is stronger than that of single linalool or (E)-beta-farnesene or 4-terpenol, and the tick repelling effect of the finally compounded tick repellent containing various compounds is better than that of single linalool or (E)-beta-farnesene or 4-terpenol; the tick repellent disclosed by the invention can be used for replacing the traditional repellent DEET. According to the tick repellent disclosed by the invention, when linalool, (E)-beta-farnesene and 4-terpene alcohol are compounded in a ratio of 2: 2: 1, the repellent rate is higher than 55% within 2 hours.

The invention discloses an artemisia annua alpha-farnesene synthase gene AaAFS as well as a mutant and application thereof, the alpha-farnesene synthase gene AaAFS is cloned from artemisia annua for the first time, the gene can specifically catalyze farnesyl pyrophosphate to synthesize alpha-farnesene, in order to further improve the enzymatic activity, AaAFS protein is analyzed, and the alpha-farnesene synthase gene AaAFS can be used as an alpha-farnesene synthase gene AaAFS. And single-site and multi-point mutants of a series of key sites are obtained. Experiments prove that a plurality of mutants (such as S387A, G292A, L487V and combinations thereof) can obviously improve the yield of alpha-farnesene, and the yield of triple mutants (S387A / G292A / L487V) is improved by about 300% compared with that of a wild type. The AaAFS gene and the high-performance mutant thereof provided by the invention provide core elements for green and efficient production of alpha-farnesene by means of synthetic biology, and have important application value in industrial and medicinal aspects.

The invention provides a separated myzus persicae odorant binding protein and an application thereof, the protein can bind odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7-triene (DMNT), (E, E)-4, 8, 12-trimethyl-1, 3, 7, 11-tridecatetraene (TMTT), E-beta-farnesene, geraniol and geranyl acetone, and the protein has the advantages that the protein can bind the odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7, 11-tridecatetraene, (E, E)-4, 8, 12- The combination of the protein and the odorant can play an important role in biological control of insects.