38 results about "Farnesene" patented technology

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention discloses a genetically engineered bacterium and an application of the genetically engineered bacterium in production of farnesene. The genetically engineered bacterium takes saccharomyces cerevisiae as a chassis strain; an exogenous beta-farnesene synthase gene is integrated, an ERG9 gene is knocked out, a promoter of a truncated HMG1 gene is replaced with an ANB1 promoter, an exogenous transhydrogenase gene is integrated and driven by a glucose sensitive promoter, beta-farnesene synthase is mutated and fused with a transmembrane structural domain of ABC transporter protein PDR10, and then a chimeric expression unit is constructed. According to the present invention, the chassis bacteria are modified by at least one of the steps of overexpression of phosphatidylcholine synthetase, knockout of sterol ester synthetase and introduction of exogenous alkyl glycerol monooxygenase, and the obtained engineering bacteria are combined with the optimized fermentation process so as to significantly improve the farnesene synthesis efficiency and the production economy; therefore, the genetically engineered bacterium and the fermentation method provided by the invention have good application prospects.

Provided are: a hot-melt adhesive composition which contains a large amount of plant-derived components, has excellent adhesive properties, in particular, 180 DEG peel adhesion, constant load retention, and shear retention, and also has high re-peelability; and an adhesive tape which has an adhesive layer that contains the adhesive composition. The hot melt adhesive composition contains at least (A) a styrene block copolymer having a farnesene structure, (B) a thermoplastic resin having a kinematic viscosity (40 DEG C) of 150 mm2 / s to 200 thousand mm2 / s or a number average molecular weight (Mn) of 450 to 4000, and (C) a tackifier resin having a softening point of 100 DEG C or more. The tackifying resin (C) is contained in an amount of 30 to 500 parts by mass per 100 parts by mass of the styrene block copolymer (A).

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

The invention relates to the field of genetic engineering and bioengineering, in particular to engineering algae capable of synthesizing alpha-farnesene and a preparation method of the engineering algae. An MEP metabolic network of synechocystis PCC 6803 is modified, through single-copy series recombination and multi-copy combination of dxs, ispA, idi and AFS genes, optimization of a farnesene MEP metabolic pathway is achieved, the carbon flux of oriented synthesis of farnesene is precisely regulated and controlled, under the optimal effect, the yield of alpha-farnesene within 9 days is 83.07 mg / L (25.82 mg / g DCW), and economic application value is achieved.

The application provides application of farnesene in prevention and treatment of southern root-knot nematode, belongs to the technical field of prevention and treatment of root-knot nematode, and the concentration of farnesene in prevention and treatment of southern root-knot nematode is 92-118 ng / h per plant. The application finds that farnesene exposure treatment can effectively inhibit the invasion and reproduction of southern root-knot nematode and significantly reduce the feeding preference of southern root-knot nematode to corn by using farnesene to expose and treat corn plants, and farnesene can improve the resistance of plants by regulating and improving the content of defense hormone jasmonic acid isoleucine complex in corn. In conclusion, the application provides a new idea for green prevention and control of southern root-knot nematode.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The invention discloses a construction method and application of alpha-farnesene-producing pichia pastoris, and belongs to the technical field of biology. The invention discloses a novel pichia pastoris engineering strain which has the capability of efficiently synthesizing alpha-farnesene. According to the strain, through metabolic pathway optimization and key enzyme high expression, the carbon flow distribution efficiency of a substrate to alpha-farnesene is remarkably improved. The yield of an excellent strain pichia pastoris mut008 obtained through ARTP mutagenesis and multiple rounds of screening reaches 3.05 g / L under the level of a 5L fermentation tank when methanol is used as a substrate, and the yield preliminarily reaches the level required by industrial production of C1 substrate utilization; when glucose is used as a substrate, the yield reaches 30.66 g / L, and the industrial production cost can be reduced.

To provide a resin composition that enables superior thermal and melt adhesion to a resin having a polar group and allows development of sufficient tensile fracture strain.SOLUTION: A resin composition comprises (A) a hydrogenated product of a block copolymer of an aromatic vinyl compound and a conjugated diene compound, (B) a polyester elastomer, (C) a crystalline polyester, and (D) an ethylene-unsaturated carboxylic acid copolymer, the resin composition optionally further containing (E) a non-aromatic rubber softener. The component (A) may have structural units derived from β-farnesene. The component (B) may include a polybutylene terephthalate-based elastomer.SELECTED DRAWING: Figure 1

Heat transfer compositions, and systems and methods using the composition, comprising: (a) a refrigerant comprising at least about 30% by weight based on all refrigerant components of trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)); and at least one compound inhibiting isomerization of said trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)) to cis-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(Z)), said at least one compound being selected from the group consisting of d-limonene, 2,6-diisopropyl naphthalene, β-pinene, farnesene, α-terpinene and combinations of two or more of these.

Described herein is an invention that includes a spreadable conditioning composition comprising a blend of: a branched hydrocarbon and an ester having a kinematic viscosity of less than or equal to about 100 centistokes. The composition may be natural, for example, if each of the branched hydrocarbon and the ester are independently vegetable-derived. In addition, the composition may lack ingredients that are derived from a palm oil. In an embodiment, the composition is a blend of hydrogenated farnesene and an ester selected from glyceryl triheptanoate, heptyl undecylenate, and mixtures thereof. The composition exhibits an average spreading velocity of about 4 to about 8. Also disclosed are formulations for use in products of personal care, home / institutional care, industry, pharmaceutical and medical and veterinary care and related methods.

There is provided a method for the selective epoxidation of farnesene using a catalyst comprising a metal M complexed with a salen ligand of formula (I).

The present invention relates to a composition comprising sinensal and sinensol, and to the use thereof as an aroma chemical. The invention relates moreover to the use of sinensol to enhance the persistence or to modify the aroma of sinensal or of a mixture of sinensal and farnesene.

This invention relates to the terpene synthase AaTPS48 from Artemisia argyi, its encoding gene, and its applications. It provides an important foundation for utilizing genetic engineering techniques to increase the content of the active components myrcene and (trans)-β-farnesene in Artemisia argyi, or to directly produce myrcene and (trans)-β-farnesene. The technical solution is that the terpene synthase AaTPS48 is a protein of the following a) or b) or c): a) the amino acid sequence of the protein shown in SEQ ID No. 1; b) a fusion protein obtained by attaching a tag to the N-terminus and / or C-terminus of the protein shown in SEQ ID No. 1; c) a protein with the same function obtained by substituting and / or deleting and / or adding one or more amino acid residues of the amino acid sequence shown in SEQ ID No. 1. The AaTPS48 protein of this invention can catalyze both GPP to form myrcene and FPP to form (trans)-β-farnesene, playing an important role in the biosynthesis of myrcene, (trans)-β-farnesene, and other terpene compounds in Artemisia argyi.

The invention belongs to the technical field of microbial fermentation. The invention relates to saccharomyces cerevisiae, in particular to saccharomyces cerevisiae with high yield of farnesene and squalene and application of the saccharomyces cerevisiae. The yeast-like yeast is constructed by the following steps: providing yeast-like host bacteria; an exogenous farnesene synthase coding gene is introduced into the yeast-like host bacteria, so that the farnesene synthase coding gene is expressed in a host; transforming a genome of the yeast-like host bacterium so as to improve the expression activity of endogenous squalene synthase of the yeast-like host bacterium; strengthening the mevalonic acid pathway of the yeast-like host bacteria; and screening to obtain an engineering strain capable of simultaneously accumulating farnesene and squalene, thereby obtaining the saccharomyces-like strain capable of producing farnesene and squalene at high yield. The genetic stability of the saccharomyces cerevisiae meets the condition that more than 90% of farnesene and squalene producing capacity is still maintained after continuous passage for 50 generations in a culture medium without selective pressure.

The application provides a beta-farnesene synthetase mutant and application thereof, and belongs to the technical field of protein engineering modification and engineering bacteria. The application firstly performs semi-rational design on beta-farnesene synthetase AanFS by using protein engineering, adopts homologous modeling, uses molecular docking and molecular dynamics simulation, and calculates a mutant beneficial to improve the activity, obtains multiple active sites with improved activity after experimental verification, combines mutation, and obtains the optimal mutant AanFS K197T / F180H The yield of beta-farnesene is increased by 283.8% compared with the wild type. Meanwhile, a Yarrowia lipolytica strain Q26 strain expressing the beta-farnesene synthetase mutant is obtained by using genetic engineering technology, the strain can utilize oleic acid and kitchen waste oil as carbon sources to produce beta-farnesene, is an excellent strain for high-yield beta-farnesene, and therefore has good practical application value.

It is provided an adhesive composition having a high biobased content and having a moderate adhesive property and high heat resistance and a method for producing the same, and an adhesive composition including: a block copolymer (X) including a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing a structural unit derived from a conjugated diene compound, and a tackifier (Y), in which the block copolymer (X) includes, as the polymer block (B), at least one polymer block (B-1) containing a structural unit derived from β-farnesene, and the block copolymer (X) include at least one selected from the group consisting of an unhydrogenated block copolymer (X0) which is a block copolymer that is not hydrogenated, and a hydrogenated block copolymer (X1) which is a hydrogenated block copolymer and has a degree of hydrogenation of less than 50 mol %.

The invention discloses an artemisia annua alpha-farnesene synthase gene AaAFS as well as a mutant and application thereof, the alpha-farnesene synthase gene AaAFS is cloned from artemisia annua for the first time, the gene can specifically catalyze farnesyl pyrophosphate to synthesize alpha-farnesene, in order to further improve the enzymatic activity, AaAFS protein is analyzed, and the alpha-farnesene synthase gene AaAFS can be used as an alpha-farnesene synthase gene AaAFS. And single-site and multi-point mutants of a series of key sites are obtained. Experiments prove that a plurality of mutants (such as S387A, G292A, L487V and combinations thereof) can obviously improve the yield of alpha-farnesene, and the yield of triple mutants (S387A / G292A / L487V) is improved by about 300% compared with that of a wild type. The AaAFS gene and the high-performance mutant thereof provided by the invention provide core elements for green and efficient production of alpha-farnesene by means of synthetic biology, and have important application value in industrial and medicinal aspects.

The invention provides a separated myzus persicae odorant binding protein and an application thereof, the protein can bind odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7-triene (DMNT), (E, E)-4, 8, 12-trimethyl-1, 3, 7, 11-tridecatetraene (TMTT), E-beta-farnesene, geraniol and geranyl acetone, and the protein has the advantages that the protein can bind the odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7, 11-tridecatetraene, (E, E)-4, 8, 12- The combination of the protein and the odorant can play an important role in biological control of insects.

The application relates to the field of chemical purification technology, in particular to a high-efficiency farnesene purification method and device based on a molecular distillation technology, which comprises the following steps: at least two-stage molecular distillation processes are adopted to separate raw material liquid containing beta-farnesene and an extractant, wherein the operation temperature of the highest-stage molecular distillation process is less than or equal to 70 DEG C, and the absolute pressure is less than or equal to 40 Pa. The method is operated at extremely low temperature and extremely high vacuum, the thermal polymerization of beta-farnesene is fundamentally inhibited, and high-efficiency, continuous and high-yield purification is realized without adding a polymerization inhibitor.

A heterophasic polypropylene composition (PC) comprising: a) 70.0 to 99.0 wt% of HECO having an MFR2 of 1.0 to 100 g / 10 min, b) 1.0 to 30.0 wt% of a hydrogenated styrene-farnesene block copolymer (HSFC), c) optionally 0.0001 to 1.0 wt% of one or more nucleating agents (NU), and d) optionally 0.01 to 5.0 wt% of one or more additional additives (A) different from the one or more nucleating agents (NU).

The use of a low molecular weight farnesene, poly(farnesene), and farnesene copolymer in a golf ball is disclosed herein. In a core, low molecular weight farnesene, poly(farnesene) or farnesene copolymer is blended with 1,4 polybutadiene or a polyalkenamer. In a mantle layer, low molecular weight farnesene, poly(farnesene), and / or farnesene copolymer can be blended with non- or partially neutralized copolymeric or terpolymeric ionomer(s). In a cover, low molecular weight farnesene, poly(farnesene), and farnesene copolymer can be blended with highly neutralized ionomer.

The invention discloses an aphidoletes aphidimyza attractant based on a compound volatile matter. The aphidoletes aphidimyza attractant comprises a compound volatile matter composition for accurately attracting aphidoletes aphidimyza, the compound volatile matter composition is prepared by mixing the following six compounds according to a specific volume ratio: n-hexanol, methyl salicylate, hexanoic acid, cis-3-hexenol, trans-beta-farnesene and geranyl acetone. The invention further discloses application of the aphidoletes aphidimyza attractant based on the compound volatile matter. Comprising the following steps of preparation of an attractant core, field arrangement, synergistic release of natural enemies and attraction control. The invention provides clear compound components and an accurate ratio, the selected compounds are chemical monomers which can be commercially purchased or synthesized, and standardized production is easy; the application mode is simple, the method can be combined with an existing trap or slow release device technology, operation of farmers is facilitated, and the method has wide industrial application prospects.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of squalane. The preparation method comprises the following steps: carrying out dimerization reaction on beta-farnesene in a solvent in the presence of a palladium catalyst and an alkaline medium to obtain a mixture; in the presence of a second catalyst, carrying out hydrogenation reduction on the obtained mixture to obtain a prepared product; the squalane has a chemical formula shown in the specification. The purity and the yield of the squalane product obtained by the preparation method are remarkably improved, the isomer proportion is greatly reduced, the reagent cost is remarkably reduced, and the generation of wastes is reduced, so that the production cost is reduced, and the method is suitable for industrial production of squalane;

The invention provides soft pear tobacco essence as well as a preparation method and application thereof. The soft pear tobacco essence disclosed by the invention is prepared from the following components in parts by mass: 30 to 40 parts of soft pear fermented concentrated juice, 0.5 to 1 part of ethyl hexanoate, 0.6 to 1.2 parts of ethyl caprylate, 0.5 to 1 part of alpha-farnesene, 1 to 1.5 parts of 1-octanol, 1 to 1.5 parts of 2, 4-ethyl sebacate, 0.5 to 0.8 part of (Z)-4-methyl decanoate, 0.02 to 0.05 part of hexanal, 0.5 to 1 part of methyl hexanoate, 0.5 to 1 part of methyl decanoate, 0.2 to 0.5 part of hexyl acetate and 50 to 60 parts of propylene glycol. Wherein the soft pear fermented concentrated juice is prepared by concentrating the soft pear fermented juice. The soft pear tobacco essence has the advantages of being strong in natural sense, lasting in fragrance, highly harmonious with tobacco fragrance and the like, the fragrance characteristic and the taste characteristic are obviously improved, and quality upgrading of the pear flavor in cigarettes is achieved.

The invention relates to a compound botanical attractant for cicada punctata and an application method of the compound botanical attractant, and the compound botanical attractant contains eudesmol and alpha-farnesene, and preferably further contains myrcene. The eucalyptol is used as a main volatile component to simulate a smell signal released by the wax cicada in the process of feeding a host plant, so that the directional behavior of the wax cicada can be triggered; alpha-farnesene and myrcene are typical terpenoids and can enhance the recognition sensitivity of the wax cicada on information odor, and the compound attractant remarkably enhances the aggregation and locking behaviors of the wax cicada. According to the invention, plant-derived natural volatile matters are adopted, so that the problems of pesticide residues and resistance caused by chemical pesticides are avoided. The slow-release bag and the insect sticking adhesive tape are low in cost, simple and convenient to operate and suitable for large-area popularization.

The invention belongs to the technical field of microorganisms and fermentation engineering, and particularly relates to Yarrowia lipolytica engineering bacteria for synthesizing beta-farnesene based on Snf1-mediated metabolic remodeling and application of the Yarrowia lipolytica engineering bacteria. Specifically, a high-yield beta-farnesene yeast engineering strain is constructed by virtue of Snf1-mediated metabolic remodeling. According to the method, yarrowia lipolytica Po1f is taken as an original strain, firstly, a beta-farnesene synthesis pathway and a non-oxidative glycolysis pathway are introduced, phosphofructokinase is knocked out to block the glycolysis pathway, so that evolution pressure is applied, and the strain is forced to remodel a metabolic network of the strain. The inactivation of GLK1 and REG1 causes continuous activation of Snf1 kinase and further drives global metabolism remodeling, so that the rigid limitation of yeast metabolism regulation is effectively relieved, and the capability of utilizing a lipid carbon source is remarkably enhanced. By further combining metabolic engineering modification with glucose-oleic acid co-culture fermentation process optimization, efficient synthesis of beta-farnesene is realized, so that the beta-farnesene has a good practical application value.

The invention discloses a brown planthopper repellent and application thereof. The brown planthopper repellent comprises the following components: farnesene, 2-heptanol, (E)-2-hexenal and paraffin oil, wherein the ratio of farnesene to 2-heptanol to (E)-2-hexenal to paraffin oil is (0.04-0.16): (0.04-0.16): (0.04-0.16): (0.4-1.6); the pesticide composition can generate a repelling effect on brown planthoppers. The repellent has the characteristics of low cost, high efficiency, environmental friendliness, safety to human and livestock and the like. The nilaparvata lugens repellent disclosed by the invention has a wide industrialization prospect, is particularly suitable for being used in pollution-free production of crops due to the simple preparation method, and has wide economic, social and ecological benefits.

The invention belongs to the field of microbial metabolism engineering and biotechnology application, and particularly relates to an engineering bacterium for biosynthesis of farnesene and a construction method and application thereof. The construction method comprises the following steps: screening beta-farnesene synthase, optimizing a host strain mevalonic acid pathway related gene, increasing the copy number of a rate-limiting step gene, enhancing the supply of acetyl coenzyme A, and optimizing the expression of exogenous beta-farnesene synthase. The hansenula polymorpha chassis cell is utilized to realize high yield of beta-farnesene, and a foundation is laid for green and mild synthesis of farnesene and efficient biotransformation of methanol.

The application discloses an alpha-farnesene synthase AoFS from Zizania and application thereof, and belongs to the field of terpene biosynthesis. The amino acid sequence of the alpha-farnesene synthase AoFS is shown as SEQ ID NO. 2, which can synthesize a main product alpha-farnesene by catalyzing a farnesyl pyrophosphate (FPP) substrate. It is identified by GC-MS that the fermentation product contains a sesquiterpene compound alpha-farnesene, and the yield shows that the catalytic effect of the alpha-farnesene synthase is better. Therefore, the application can realize the synthesis of alpha-farnesene in microbial cells, effectively reduce the production cost, be favorable to the high-efficiency production of alpha-farnesene, provide technical support for the heterologous preparation of the terpene compound alpha-farnesene by using a synthetic biology method, and is favorable to the selection of the best alpha-farnesene synthase in different chassis strains by researchers so as to produce alpha-farnesene in a high yield.