72 results about "Farnesene" patented technology

The invention discloses production of terpenoids and a strain, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing linalool, isoprene, isopentenol, 1, 3, 4-triterpenes and 1, 3, 4-triterpenes. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 40.72 g.L <-1 >.

The invention belongs to the technical field of bioengineering, and particularly relates to an application of EcorOBP7 in combination with odor information molecules, and the nucleotide sequence of the EcorOBP7 is as shown in SEQ ID NO.1; the odor information molecules comprise at least one of (E)-beta-farnesene, (E)-beta-myrcene, 3-methylbutyraldehyde, (Z)-beta-ocimene, linalool and cis-acetamino acetate. The odor information molecules are used for detecting the odor of the odor information molecules, and the odor information molecules comprise at least one of (E)-beta-farnesene and (E)-beta-myrcene. The invention finds that EcorOBP7 is a broad-spectrum binding protein, can interact with various information molecules, and can be strongly bound with substances such as (E)-beta-farnesene and cis-acetamido acetate, so that EcorOBP7 can sense odor molecules in the environment through EcorOBP7 highly expressed on antennas of EcorOBP7. Female insects can find proper hosts and spawning sites by distinguishing volatile substances of plants, male insects can find the female insects for mating through perceptual pheromones, and it is indicated that the protein can adjust the foraging and spawning behaviors of eutrophus maculans.

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention discloses a method for producing terpenoids, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing isoprene, isopentenol, 1, 3, 4-triterpenes, 1, 3, 4-triterpenes and the like. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 13.49 g.L <-1 >.

The invention discloses a genetically engineered bacterium and an application of the genetically engineered bacterium in production of farnesene. The genetically engineered bacterium takes saccharomyces cerevisiae as a chassis strain; an exogenous beta-farnesene synthase gene is integrated, an ERG9 gene is knocked out, a promoter of a truncated HMG1 gene is replaced with an ANB1 promoter, an exogenous transhydrogenase gene is integrated and driven by a glucose sensitive promoter, beta-farnesene synthase is mutated and fused with a transmembrane structural domain of ABC transporter protein PDR10, and then a chimeric expression unit is constructed. According to the present invention, the chassis bacteria are modified by at least one of the steps of overexpression of phosphatidylcholine synthetase, knockout of sterol ester synthetase and introduction of exogenous alkyl glycerol monooxygenase, and the obtained engineering bacteria are combined with the optimized fermentation process so as to significantly improve the farnesene synthesis efficiency and the production economy; therefore, the genetically engineered bacterium and the fermentation method provided by the invention have good application prospects.

Provided are: a hot-melt adhesive composition which contains a large amount of plant-derived components, has excellent adhesive properties, in particular, 180 DEG peel adhesion, constant load retention, and shear retention, and also has high re-peelability; and an adhesive tape which has an adhesive layer that contains the adhesive composition. The hot melt adhesive composition contains at least (A) a styrene block copolymer having a farnesene structure, (B) a thermoplastic resin having a kinematic viscosity (40 DEG C) of 150 mm2 / s to 200 thousand mm2 / s or a number average molecular weight (Mn) of 450 to 4000, and (C) a tackifier resin having a softening point of 100 DEG C or more. The tackifying resin (C) is contained in an amount of 30 to 500 parts by mass per 100 parts by mass of the styrene block copolymer (A).

The invention relates to the use of a composition (C) comprising, for 100% of the weight thereof,—from 10% by weight to 90% by weight of at least one poly(farnesene) polymer having a number-average molecular weight of greater than or equal to 10,000 g / mol and less than or equal to 120,000 g / mol, said poly(farnesene) polymer being partially or totally hydrogenated and / or functionalized with hydroxyl radicals, and—from 10% by weight to 90% by weight of a mixture (M) of hydrocarbons in which at last 94% by weight of said hydrocarbons comprise from 15 to 19 carbon atoms, for preventing and / or slowing the appearance of unattractive effects on human hair following exposure to intense heat. The invention also relates to a method for drying and shaping the hair, using said composition.

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

Described herein is a method for making intermediates in the production of fragrance components starting from β-farnesene via a mixture comprising an epoxide represented by formula (III) as defined herein and an epoxide represented by formula (IV). In particular, methods for making acetylmethyl farnesol and hydroxyfarnesyl acetone and their homologues are described.

Disclosed are: a hydrogenated product of a block copolymer having a low glass transition temperature and exhibiting good flexibility, rubber elasticity, and elongation property even in a low temperature region; a resin composition; and a method for producing the hydrogenated product of the block copolymer, in which the hydrogenated product of the block copolymer contains a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing a structural unit derived from a conjugated diene compound, and satisfies the following conditions (1) to (3): (1) the structural unit derived from the conjugated diene compound in the polymer block (B) has a structural unit derived from butadiene and a structural unit derived from isoprene, but does not have a structural unit derived from farnesene; (2) the hydrogenated product of the block copolymer has a glass transition temperature of -50°C or lower; and (3) when a weight average molecular weight of the hydrogenated product of the block copolymer is defined as x and a crystallization temperature of the hydrogenated product of the block copolymer is defined as y (°C), 5.8x / 100,000 - y > 17 is satisfied.

The present invention provides a process for preparing a 2-(3-alkenyl)-1,3-butadiene compound of the following general formula (A), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), the process comprising the step of subjecting a secondary allylsulfone compound of the following general formula (G), wherein R1 and R2 represent, independently of each other, a hydrogen atom or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms and optionally having an unsaturated bond(s), W represents an arenesulfonyl group, and Z represents a halogen atom, to a reductive removal of an arenesulfonyl group, W, at an allyl position, and then subjecting the secondary allylsulfone compound (G) to an elimination reaction of a hydrogen halide, HZ, in this order or in reverse order, to form the 2-(3-alkenyl)-1,3-butadiene compound (A).

The invention discloses a recombinant strain for producing farnesene as well as a construction method and application thereof. The construction method comprises the following steps: preparing a pFII plasmid containing farnesene synthase, farnesyl pyrophosphate synthase and isopentene diphosphate isomerase; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing the primer 1 and the primer 2 to obtain a fragment 1; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing a primer 3 and a primer 4 to obtain a fragment 2; taking the pFII plasmid as a template, and carrying out PCR (Polymerase Chain Reaction) amplification by utilizing a primer 5 and a primer 6 to obtain a fragment 3; carrying out seamless connection on the fragment 1, the fragment 2 and the fragment 3 to obtain a plasmid 1; introducing a plasmid 1, a plasmid 2 and a plasmid 3 into escherichia coli to obtain a recombinant strain for producing farnesene; the farnesene yield of the recombinant strain 1 constructed by the invention is 3.3 g / L within 96 hours, and technical support and data reference are provided for large-scale preparation of biological fuel farnesene by a biological method.

A method for the industrial production of teprenone and its application. The present invention belongs to the field of teprenone synthesis. The purpose of the present invention is to solve the technical problems of the existing teprenone synthesis method, which has a long route, many side reactions, and requires the use of special reagents. The method of the present invention comprises the following steps: first, farnesene is reacted with acetoacetate in the presence of a catalyst to obtain farnesene ketone ester, which is then decarboxylated to produce farnesene acetone, and then subjected to a reduction reaction, a halogenation reaction, and a Wittig reaction to obtain teprenone. The method avoids the shortcomings of existing processes, has fewer conversion steps in the synthesis route, and produces teprenone with high yield and purity, making it suitable for industrial production. The teprenone of the present invention is used as a drug for treating gastric diseases.

The invention relates to the field of genetic engineering and bioengineering, in particular to engineering algae capable of synthesizing alpha-farnesene and a preparation method of the engineering algae. An MEP metabolic network of synechocystis PCC 6803 is modified, through single-copy series recombination and multi-copy combination of dxs, ispA, idi and AFS genes, optimization of a farnesene MEP metabolic pathway is achieved, the carbon flux of oriented synthesis of farnesene is precisely regulated and controlled, under the optimal effect, the yield of alpha-farnesene within 9 days is 83.07 mg / L (25.82 mg / g DCW), and economic application value is achieved.

The application provides application of farnesene in prevention and treatment of southern root-knot nematode, belongs to the technical field of prevention and treatment of root-knot nematode, and the concentration of farnesene in prevention and treatment of southern root-knot nematode is 92-118 ng / h per plant. The application finds that farnesene exposure treatment can effectively inhibit the invasion and reproduction of southern root-knot nematode and significantly reduce the feeding preference of southern root-knot nematode to corn by using farnesene to expose and treat corn plants, and farnesene can improve the resistance of plants by regulating and improving the content of defense hormone jasmonic acid isoleucine complex in corn. In conclusion, the application provides a new idea for green prevention and control of southern root-knot nematode.

A resin composition containing an ethylene-vinyl acetate copolymer (I) and a hydrogenated block copolymer (II), wherein the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) containing a polymer block (A) containing a structural unit derived from an aromatic vinyl compound and a polymer block (B) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, wherein the hydrogenation rate of carbon-carbon double bonds in the structural unit derived from a conjugated diene in the block copolymer (P) is 70 mol % or more, and in the resin composition, the content of the ethylene-vinyl acetate copolymer (I) is 40 to 95% by mass and the content of the hydrogenated block copolymer (II) is 5 to 60% by mass.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The invention discloses a construction method and application of alpha-farnesene-producing pichia pastoris, and belongs to the technical field of biology. The invention discloses a novel pichia pastoris engineering strain which has the capability of efficiently synthesizing alpha-farnesene. According to the strain, through metabolic pathway optimization and key enzyme high expression, the carbon flow distribution efficiency of a substrate to alpha-farnesene is remarkably improved. The yield of an excellent strain pichia pastoris mut008 obtained through ARTP mutagenesis and multiple rounds of screening reaches 3.05 g / L under the level of a 5L fermentation tank when methanol is used as a substrate, and the yield preliminarily reaches the level required by industrial production of C1 substrate utilization; when glucose is used as a substrate, the yield reaches 30.66 g / L, and the industrial production cost can be reduced.

A thermoplastic elastomer composition including an acrylic block copolymer (I) and a hydrogenated block copolymer (II). The content of the acrylic block copolymer (I) is 70 to 300 parts by mass with respect to 100 parts by mass of the hydrogenated block copolymer (II); the hydrogenated block copolymer (II) is a hydrogenated product of a block copolymer (P) including a polymer block (A1) containing structural units derived from an aromatic vinyl compound, and a polymer block (B1) containing 1 to 100 mass % of structural units (b1) derived from farnesene and 99 to 0 mass % of structural units (b2) derived from a conjugated diene other than farnesene, the mass ratio [(A1) / (B1)] of the polymer block (A1) to the polymer block (B1) being 1 / 99 to 70 / 30; and the hydrogenation ratio of carbon-carbon double bonds in the polymer block (B1) is 50 to 100 mol %.

To provide an active energy ray-curable composition which has a low viscosity and is capable of yielding a cured product having excellent transparency as well as excellent flexibility and heat resistance; a cured product thereof; and a layered product.SOLUTION: An active energy ray-curable composition contains: a urethane (meth)acrylate (X) having a structural unit derived from farnesene; a (meth)acrylate (Y) other than the urethane (meth)acrylate (X); and a photopolymerization initiator (Z). Also provided are: a cured product of the active energy ray-curable composition; and a layered product that comprises a layer containing at least one of the active energy ray-curable composition and the cured product, and two or more transparent base materials.SELECTED DRAWING: None

To provide a resin composition that enables superior thermal and melt adhesion to a resin having a polar group and allows development of sufficient tensile fracture strain.SOLUTION: A resin composition comprises (A) a hydrogenated product of a block copolymer of an aromatic vinyl compound and a conjugated diene compound, (B) a polyester elastomer, (C) a crystalline polyester, and (D) an ethylene-unsaturated carboxylic acid copolymer, the resin composition optionally further containing (E) a non-aromatic rubber softener. The component (A) may have structural units derived from β-farnesene. The component (B) may include a polybutylene terephthalate-based elastomer.SELECTED DRAWING: Figure 1

Heat transfer compositions, and systems and methods using the composition, comprising: (a) a refrigerant comprising at least about 30% by weight based on all refrigerant components of trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)); and at least one compound inhibiting isomerization of said trans-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(E)) to cis-1-chloro-3,3,3-trifluoropropene (HFCO-1233zd(Z)), said at least one compound being selected from the group consisting of d-limonene, 2,6-diisopropyl naphthalene, β-pinene, farnesene, α-terpinene and combinations of two or more of these.

Described herein is an invention that includes a spreadable conditioning composition comprising a blend of: a branched hydrocarbon and an ester having a kinematic viscosity of less than or equal to about 100 centistokes. The composition may be natural, for example, if each of the branched hydrocarbon and the ester are independently vegetable-derived. In addition, the composition may lack ingredients that are derived from a palm oil. In an embodiment, the composition is a blend of hydrogenated farnesene and an ester selected from glyceryl triheptanoate, heptyl undecylenate, and mixtures thereof. The composition exhibits an average spreading velocity of about 4 to about 8. Also disclosed are formulations for use in products of personal care, home / institutional care, industry, pharmaceutical and medical and veterinary care and related methods.

The invention relates to the technical field of genetic engineering, in particular to an engineering bacterium for producing beta-farnesene and application of the engineering bacterium. According to the invention, different advantage modification strategies are matched for the existing engineering strain for producing the beta-farnesene, the YPL062W knockout chassis modification strategy is applied to the biosynthesis of the beta-farnesene for the first time, and the production capacity of the beta-farnesene is greatly improved in combination with ERG9 down-regulation.

There is provided a method for the selective epoxidation of farnesene using a catalyst comprising a metal M complexed with a salen ligand of formula (I).

The invention belongs to the field of enzyme engineering, and particularly relates to terpene cyclase mutants capable of changing catalytic products and application. According to the specific technical scheme, the terpenoid cyclase mutant is characterized in that 64 amino acids are truncated at the N end of wild type terpenoid cyclase BcABA3, then the truncated terpenoid cyclase BcABA3 is mutated, and the amino acid sequence of the wild type terpenoid cyclase BcABA3 is as shown in SEQ ID NO: 1. The invention provides a method for improving terpenoid cyclase and controlling product distribution condition, which specifically comprises the following steps: truncating wild type terpenoid cyclase, and then carrying out specific point mutation. Based on the method, four new terpenoid cyclases are further provided, and compared with wild type terpenoid cyclases, when the new terpenoid cyclases catalyze farnesyl pyrophosphate, farnesene can be prepared in a targeted mode, and the distribution condition of farnesene or ionylideneane in a product can be controlled.

By using as a polyol component and as a copolymer component of poly(farnesene) diol and ε-caprolactone, a polyurethane composition and method having mechanical properties comparable to the most performance-commercial elastomeric materials are described. The poly(farnesene) diol is produced from biobased monomers, and such copolymerization enables the incorporation of renewable materials into high-performance polyurethane materials.

Provided are: an active energy ray-curable composition which has a low viscosity, exhibits excellent transparency, and can yield a cured product having excellent flexibility and heat resistance; a cured product thereof; and a layered product.　The active energy ray-curable composition contains: a urethane (meth)acrylate (X) having a structural unit derived from farnesene; a (meth)acrylate (Y) other than the urethane (meth)acrylate (X); and a photopolymerization initiator (Z). The cured product is made of the active energy ray-curable composition. The layered product comprises: a layer containing at least one of the active energy ray-curable composition and the cured product; and two or more transparent base materials.

The present invention relates to a composition comprising sinensal and sinensol, and to the use thereof as an aroma chemical. The invention relates moreover to the use of sinensol to enhance the persistence or to modify the aroma of sinensal or of a mixture of sinensal and farnesene.

This invention relates to the terpene synthase AaTPS48 from Artemisia argyi, its encoding gene, and its applications. It provides an important foundation for utilizing genetic engineering techniques to increase the content of the active components myrcene and (trans)-β-farnesene in Artemisia argyi, or to directly produce myrcene and (trans)-β-farnesene. The technical solution is that the terpene synthase AaTPS48 is a protein of the following a) or b) or c): a) the amino acid sequence of the protein shown in SEQ ID No. 1; b) a fusion protein obtained by attaching a tag to the N-terminus and / or C-terminus of the protein shown in SEQ ID No. 1; c) a protein with the same function obtained by substituting and / or deleting and / or adding one or more amino acid residues of the amino acid sequence shown in SEQ ID No. 1. The AaTPS48 protein of this invention can catalyze both GPP to form myrcene and FPP to form (trans)-β-farnesene, playing an important role in the biosynthesis of myrcene, (trans)-β-farnesene, and other terpene compounds in Artemisia argyi.