6 results about "Benzyl cyanide" patented technology

This invention relates to a trifluoromethyl-substituted pyrene-phenylacetonitrile derivative, its preparation method, and its application. A trifluoromethyl-substituted pyrene-phenylacetonitrile derivative has the structural formula: [formula omitted]. The preparation method involves dissolving 1-pyrene formaldehyde, the corresponding trifluoromethylphenylacetonitrile, and an alkaline catalyst in an organic solvent, and carrying out a Knoevenagel condensation reaction under heating conditions. The reaction product is then post-treated to obtain the pyrene-phenylacetonitrile derivative. The application of a trifluoromethyl-substituted pyrene-phenylacetonitrile derivative in electrical storage devices is also discussed. This invention achieves precise control of storage performance by introducing trifluoromethyl groups at different positions on the benzene ring of the pyrene-phenylacetonitrile backbone, providing a novel design approach for developing new multi-level electrical storage materials. The synthesis route is concise and has broad application prospects in the field of high-density non-volatile memory.

This invention discloses a reverse electrically controlled dimming film based on a photopolymerizable monomer and a negative nematic liquid crystal system, and its preparation method. The film includes a liquid crystal cell or a liquid crystal film, and a liquid crystal composite system infused within the liquid crystal cell or liquid crystal film. The liquid crystal composite system comprises 50.0–96.0 wt% of a negative nematic liquid crystal mixture, 4.00–50.0 wt% of a photopolymerizable monomer, and 0.2–10.0% of a photo-leaving photoinitiator by mass of the total photopolymerizable monomer. The photo-leaving photoinitiator is an o-nitrophenyl compound, a benzothiophene iminophenylacetonitrile compound, or a mixture thereof. The reverse electrically controlled dimming film prepared by this invention has a visible light transmittance of less than or equal to 1% under a low-frequency electric field, a near-infrared light transmittance of less than or equal to 22%, and a visible light and near-infrared light transmittance of greater than or equal to 80% in the un-energized state. It has low energy consumption, low driving voltage and response time, and the preparation process is simple, energy-saving, and environmentally friendly.

The invention relates to a preparation method and application of a novel benzyl cyanide ester insect covalent pheromone, the benzyl cyanide ester insect covalent pheromone is a compound with the following structural figure (1), R-C = O is allyloyl, 2, 5-dioxo-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5-difluoro-2, 5- wherein, in the formula I, R1, R2, R3, R4, R5, R6, R7, R7, R7, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8 Wherein R1, R2, R3, R4, R5 are cyano or ethyl cyano or hydrogen, hydrogen or cyano or ethyl cyano, hydrogen or cyano or ethyl cyano, hydrogen or cyano or ethyl cyano, hydrogen or cyano or ethyl cyano, hydrogen or cyano or ethyl cyano, hydrogen or methoxyl; y is nitrogen or oxygen; and n is 0, 1, 2 or 3.

The application discloses a method for preparing phenylacetonitrile based on a continuous flow dynamic microreactor. By regulating the flow rates of the two-phase reactants of benzyl chloride and sodium cyanide containing a phase transfer catalyst, the residence time of the reaction is regulated. Meanwhile, the flow rate ratio of the two-phase reactants is dynamically adjusted according to the real-time feedback of the yield of phenylacetonitrile, so that the fine control of the cyanation reaction is realized. The microreactor of the application is built-in with magnetic stirring. On the one hand, the microdroplets with excellent dispersibility are formed, which has excellent process intensification effect on the cyanation reaction, greatly improves the phase transfer catalytic efficiency, and makes the yield of phenylacetonitrile increase to more than 97%, and the reaction time is reduced to 30 minutes. The space-time yield is increased from 460 g / (m 3 ·min) of the tank process to 13000 g / (m 3 ·min), which is increased by about 30 times. On the other hand, the sodium chloride particles can be continuously broken, avoiding the blockage of the microchannel caused by the deposition and aggregation of sodium chloride particles, solving the problem that the ordinary microchannel reactor cannot cope with the high solid content system, and ensuring the long-period stable operation.

Methods for preparing substituted phenylacetonitrile and substituted phenylacetic acid are provided. The methods disclosed herein provide for yields of phenylacetic acid or derivatives thereof, as determined from benzoic acid starting materials, of greater than 75%, and require fewer steps or dangerous reagents and solvents than known methods. These substituted phenylacetic acids can be found for use in the preparation of novel active ingredients, such as GLP-1 receptor agonists, in the field of diabetes.

This invention relates to a novel isoflavone compound represented by formula (I), a method for preparing this compound, and its use in the preparation of neuroprotective small molecule drugs. The general chemical formula of this compound is shown in formula (I). The compound in formula (I) is prepared by reacting a polyphenolic compound with a substituted phenylacetonitrile, or by reacting a polyphenolic compound with a substituted phenylacetic acid. A series of neuroprotective activity experiments have demonstrated that the compound described in this invention possesses excellent neuroprotective activity, and the compound with the best activity also exhibits acetylcholinesterase inhibitory activity, making it suitable as a lead molecule for the development of neuroprotective and neurodegenerative disease drugs. The preparation process of this invention is simple, the raw materials are inexpensive and readily available, and the product has high purity. (I).