13 results about "Stilbene derivative" patented technology

The present invention relates to a method for imitating or enhancing the perception or taste of alcohol in an edible preparation, in which an edible preparation is brought into contact with at least one component, wherein the component is selected from the group comprising stilbene, stilbene derivatives, plant extract containing stilbene and / or at least one stilbene derivative, or a mixture thereof.

The present invention relates to a method for mimicking or enhancing the alcohol perception or flavour of a consumable preparation by using at least one component (S) which is selected from the group comprising stilbene, stilbene derivatives, plant extract containing stilbene and / or at least one stilbene derivative, or a mixture thereof, and in particular bringing a consumable preparation into contact with such at least one component (S).

Provided in the present disclosure are stilbene derivatives, a preparation method therefor and the use thereof. Specifically, provided in the present disclosure is the use of compounds represented by formula (I-1), and stereoisomers, pharmaceutically acceptable salts or prodrugs thereof as an aryl hydrocarbon receptor (AHR) regulator. Compared with marketed drug Benvitimod, the compounds represented by formula I-1 have greatly improved molecular structure stability under illumination, thus overcoming photoinstability of Benvitimod, and solving the problem of Benvitimod being liable to degrade under illumination. In addition, the compounds represented by formula I-1 have remarkably improved activity on AHR protein. And finally, the preparation method for the compounds represented by formula I-1 is simple, and can achieve gram-level or kilogram-level preparation. Therefore, the compounds have better prospects in subsequent preparation development, safety and clinical use.

The application discloses a biphenyl derivative photoinitiator, a preparation method thereof, a photocuring film material and a preparation method and application thereof. The biphenyl derivative photoinitiator has a structural formula as shown in formula (I), R1 is an electron donor group, and R2 is an electron acceptor group. In the application, the biphenyl is used as a main body structure, different donor groups R1 and acceptor groups R2 are connected, a photoinitiator is synthesized through a Suzuki reaction, and a polymer monomer material is N,N-dimethyl acrylamide (DMA). The photocuring material with long afterglow luminescence can be obtained through a method of ultraviolet light irradiation, under the irradiation of a 365 nm ultraviolet lamp, the initiator absorbs photons to generate active species to attack double bonds in monomers to initiate a polymerization reaction. The photocuring film can produce long afterglow luminescence for several seconds after light irradiation, and can be applied to aspects of anti-counterfeiting, 3D printing and photolithography.

The present disclosure relates to use of a stilbene derivative in the prevention and / or treatment of ulcers. A compound of formula (I) or a pharmaceutically acceptable salt thereof can effectively prevent or treat ulcers, and in particular, has a curative effect on oral ulcers.

The present application provides the use of a compound represented by Formula I, a stereoisomer, a pharmaceutically acceptable salt or a prodrug thereof as an aryl hydrocarbon receptor (AHR) modulator. The compound represented by Formula I greatly improves the light stability of the molecular structure compared to the marketed drug benvepidimod, improves the light instability of benvepidimod, and is easily degraded under light. In addition, the activity on the AHR protein is also significantly improved. Finally, the preparation method of the compound represented by Formula I is simple, and can be prepared in kilograms or kilograms, which has a better prospect in subsequent formulation development, safety and clinical application.

The present application provides a polygonum multiflorum starch-stilbene derivative complex, a preparation method and application thereof, and belongs to the technical field of starch complexes. The polygonum multiflorum starch is compounded with the stilbene derivative (or the polygonum multiflorum starch, polysaccharide and stilbene derivative are compounded), which is beneficial to improve the stability of the stilbene derivative. Specifically, after the polygonum multiflorum starch and the stilbene derivative form the complex, the amylose in the starch and the stilbene derivative are tightly wrapped, so that the hydrolysis of the digestive enzyme is slowed down, and the digestibility of the polygonum multiflorum starch is affected. The starch or starch + polysaccharide wrapped stilbene derivative can enhance the bioavailability of the stilbene derivative in the body. The polygonum multiflorum starch-stilbene derivative complex has a stable structure, the compounding degree is more than 80%, the release rate of the stilbene derivative in the simulated gastrointestinal fluid is effectively slowed down, and the biological activity of the stilbene derivative is better maintained.

The present disclosure provides a stilbene derivative, a preparation method and use thereof, in particular, the present disclosure provides a compound represented by formula (I-1), a stereoisomer, a pharmaceutically acceptable salt or a prodrug thereof as an aromatic hydrocarbon receptor (AHR) modulator. The compound represented by formula I-1 greatly improves the light stability of the molecular structure compared with the marketed drug benvepick, improves the light instability of benvepick, and is easily degraded under light. In addition, the activity on AHR protein is also significantly improved. Finally, the preparation method of the compound represented by formula I-1 is simple, and can be prepared in kilograms or kilograms, which has a better prospect in subsequent preparation development, safety and clinical application.

Stilbene derivatives, a preparation method therefor and the use thereof are provided. Compounds of formula (I-1), and stereoisomers, pharmaceutically acceptable salts or prodrugs thereof can serve as an aryl hydrocarbon receptor (AHR) regulator. Compared with marketed drug Benvitimod, the compounds of formula I-1 have greatly improved molecular structure stability under illumination, thus overcoming photoinstability of Benvitimod, and solving the problem of Benvitimod being liable to degrade under illumination. In addition, the compounds of formula I-1 have remarkably improved activity on AHR protein. And finally, the preparation method for the compounds of formula I-1 is simple, and can achieve gram-level or kilogram-level preparation.

A stilbene derivative can be used in the prevention and / or treatment of ulcers. A compound of formula (I) or a pharmaceutically acceptable salt thereof can effectively prevent or treat ulcers, and in particular, has a curative effect on oral ulcers.

The invention discloses a light capture system based on a dicyanostilbene derivative and a preparation method and application thereof. According to the light capture system, a supermolecular nano aggregate formed by assembling a p-methylpyridinium modified dicyanostilbene derivative and polyacrylic acid through electrostatic interaction is used as a light capture antenna and an energy donor, and a fluorescent dye loaded on the supermolecular nano aggregate is used as an energy receptor. The light capture system provided by the invention has a wide color regulation and control range and remarkably enhanced active oxygen (including < 1 > O2 and O2) generation capability. Under the water phase condition, the light capture antenna of the system can enhance the generation of ROS, and after the fluorescent dye is loaded, the ROS is further enhanced.

The present invention relates to stilbene derivatives and a method for preparing the same. More particularly, the present invention relates to novel stilbene derivatives which inhibit the function of cyclophilins and are effective in preventing cyclophilin-related diseases or treating symptoms thereof, and a method for preparing the same.