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152 results about "Stilbene derivative" patented technology

Stilbene Derivative. Stilbenes are an important family of bioactive molecules that are normally associated with plants where the stilbene is produced in response to stress (Shen, Wang, & Radax, 2009).

Anti-tumor composition

The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.
Owner:AJINOMOTO CO INC

Functionalized stilbene derivatives as improved vascular targeting agents

Novel stilbenoid compounds and their prodrug forms are disclosed, which serve as potent vascular targeting agents useful for the treatment of solid tumor cancers and other diseases associated with unwanted neovascularization. The novel stilbenoid compounds are tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and combretastatin A-4. The prodrug forms serve as potent vascular targeting agents (VTAs) useful for the treatment of solid tumor cancers and diseases associated with retinal neovascularization.
Owner:BAYLOR UNIVERSITY +1

Stilbene derivatives and their use for binding and imaging amyloid plaques

This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

Stilbene derivatives, light-emitting element and light-emitting device

The present invention provides a novel substance having an excellent color purity of blue, a light-emitting element and a light-emitting device using the novel substance. A stilbene derivative has a structure shown by the general formula (1). In the general formula (1), R1 is hydrogen, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 25 carbon atoms. R2 is an alkyl group having 1 to 4 carbon atoms or an aryl group having 6 to 25 carbon atoms. Each of R3 to R5 is hydrogen or an alkyl group having 1 to 4 carbon atoms. Ar1 is an aryl group having 6 to 25 carbon atoms.
Owner:SEMICON ENERGY LAB CO LTD

Synthesis of novel organic luminescent material containing carbazolyl toluylene derivant structure and application thereof

The invention relates to novel luminous material containing a carbazyl stilbene derivative structure, which belongs to the technical field of the organic luminous materials. When the synthesis is performed, two carbazyl diphenyl ketones (2) are connected by an aromatic compound containing two ylide groups; or the carbazyl diphenyl ketones are changed into an intermediate body (3) or an intermediate body (4) firstly, and then the carbazyl stilbene is coupled by a crossed coupling method. The art of the synthetic method provided by the invention is simple, the purification is easy, the synthesized organic luminous material containing the carbazyl stilbene derivative structure has a high thermal stability, a high glass-transition temperature and a strong illumination intensity, the material is suitable for preparing the material of photogenic layers in organic electroluminescent material devices, the luminous material with aggregation-induced emission effect can be serviced as stimuli-response functional material to be applied to chemical / biochemical sensors.
Owner:SUN YAT SEN UNIV

Stilbene derivative with 1,3,4-oxadiazole and preparation method and application thereof

The invention provides a stilbene derivative with 1,3,4-oxadiazole and a preparation method and application thereof. The preparation method of the stilbene derivative with 1,3,4-oxadiazole comprises four specific reaction steps, namely oxidation cyclization reaction, NBS (N-bromosuccinimide) bromination reaction, triethyl phosphite esterification reaction and Wittig-Honner reaction. The stilbene derivative with 1,3,4-oxadiazole disclosed by the invention can be used to obviously inhibit the growing activities of Lepidopteron such as beet armyworm and cabbage looper and have important application value in the developments of environmentally friendly, efficient and new pesticides.
Owner:SOUTH CHINA UNIV OF TECH

Application of stilbene derivative and pharmaceutically acceptable salts thereof to preparation of medicines for treating hyperuricemia

The invention relates to application of a stilbene derivative and pharmaceutically acceptable salts thereof to preparation of medicines or health-care products for preventing and / or treating hyperuricemia, and acute gout, chronic gout, gouty arthritis, gout attack, uric acid nephrolithiasis and gouty nephropathy caused by the hyperuricemia. The stilbene derivative is used as an active component for preparing the medicines for treating the hyperuricemia, can reduce the concentration of uric acid in blood, has a significant effect on treatment of the hyperuricemia, does not have toxic or side effects and has good safety.
Owner:NANJING BAOHE BIOTECH

Method for oxidation synthesis of stilbenes by hexamethylenetetramine

The invention discloses a method for oxidation synthesis of stilbenes by hexamethylenetetramine, comprising the following steps: preparing halogenated hydrocarbon by substituted benzyl alcohol, oxidizing the halogenated hydrocarbon by the hexamethylenetetramine to prepare corresponding substituted benzaldehydes, and preparing stilbene derivatives by condensation of Wittig-Horner. The method is simple and easy to implement; the reactants involved in the process of synthesis are safe; the resultants produce no pollution to the environment, have low cost and high yield and are suitable for industrially producing stilbenes having antibacterial action, such as resveratrol, pterostilbene and 3, 5-dimethoxy-4-isopropyl stilbene, etc.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device

A novel stilbene derivative is provided with motivation of providing a blue emissive material showing excellent color purity. The use of the stilbene derivative of the present invention allows the fabrication of a blue-emissive light-emitting element with excellent color purity. The invention also includes an electronic device equipped with a display portion in which the stilbene derivative is employed. The stilbene derivative of the present invention is represented by formula (1), in which Ar1 and Ar2 may form a 5-membered ring by being directly bonded to each other. In formula (1), A11 represents any one of substituents represented by general formulas (1-1) to (1-3). The variables shown in formula (1) and (1-1) to (1-3) are as defined in the specification.
Owner:SEMICON ENERGY LAB CO LTD

Stilbenoid derivatives and their uses

The present invention generally provides stilbenoid derivatives and methods for using stilbenoid derivatives to modulate the activity of cannabinoid receptors or scavenge reactive nitrogen species.
Owner:ARKANSAS STATE UNIVERSITY +1

Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques

This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA +1

Stilbene derivatives and their use for binding and imaging amyloid plaques

This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

Stilbene derivatives as new cancer therapeutic agents

Stilbene derivatives exhibit killing and suppression of growth activity against a variety of cancer cells, and are effective at suppressing tumor growth in vivo. The stilbene derivatives may be used in the treatment of diseases characterized by cell hyperproliferation including human malignancies and non-malignant diseases such as liver cirrhosis. Stilbenes may also disrupt abnormal vessels in tumor to achieve vascular disrupting effect to suppress tumor growth. Water soluble pro-drug forms of stilbene derivatives are particularly useful in suppressing tumor growth in vivo.
Owner:VIRGINIA COMMONWEALTH UNIV

Stilbene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Device

The present invention provides a novel organic compound having excellent heat resistance. By using the novel organic compound, a light-emitting element and a light-emitting device which have excellent heat resistance can be provided. A stilbene derivative expressed by the general formula (1) is provided. Since the stilbene derivative expressed by the general formula (1) has high glass transition point, when it is used for a light-emitting element, the light-emitting element, and a light-emitting device using the light-emitting element which have excellent heat resistance can be obtained. Further, since the stilbene derivative expressed by the general formula (1) has good light emission efficiency; therefore, when it is used for a light emitting element, a light emitting element and a light emitting device which consumes less power can be obtained.
Owner:SEMICON ENERGY LAB CO LTD

Compositions and its use in treating obesity or inducing weight loss

The present invention provides a composition comprising polyisoprenylated benzophenone derivative and at least one component selected from stilbene derivative and anthocyanins. The composition inhibits adipogenesis and is therefore useful in treating obesity or weight loss.
Owner:SAMI LABS LTD

Molecular probes for detecting lipid composition

A method of detecting myelin in a subject includes administering to the subject a molecular probe that includes a fluorescent trans stilbene derivative and detecting the amount or distribution of the molecular probe in a tissue of interest of the subject.
Owner:CASE WESTERN RESERVE UNIV

Treatment of meningiomas using phenylbenzothiazole, stilbene, biphenylalkyne, or pyridine derivatives

A method and composition for treating a meningioma in a subject are disclosed. The method includes the step of administering to the subject a therapeutically effective amount of a composition including a cytotoxic agent associated with a phenylbenzothiazole derivative or a stilbene derivative or a biphenylalkyne derivative that accumulates within meningiomas. In one version of the method, the phenylbenzothiazole derivative is a compound of formula (V).
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Stilbene Derivative, Light Emitting Element, Light Emitting Device, and Electronic Appliance

An object is to provide a novel substance which exhibits blue light emission with excellent color purity, and to provide a light emitting element and a light emitting device using the novel substance. A stilbene derivative represented by the general formula (G1) is provided. Note that in the general formula (G1), each of A1 and B1 represents any one of structures represented by the following general formulae (G1-1) to (G1-4). In addition, in each of the general formulae (G1-1) to (G1-4), each of R1 to R24 represents any one of hydrogen and an alkyl group having 1 to 4 carbon atoms. Such a stilbene derivative can exhibit blue light emission with excellent color purity.
Owner:SEMICON ENERGY LAB CO LTD
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