19 results about "Reactive nitrogen" patented technology

The invention relates to a diatomic iron-iron site nano-enzyme constructed by relieving oxidative stress and cartilage degeneration and used for targeted osteoarthritis treatment. According to the invention, a nitrogen-doped porous carbon anchored diatomic iron nano enzyme catalyst (Fe2-NCs) with Fe-Fe dimer coordination is developed by using a'subject-object 'strategy. The Fe2-NCs protect cartilage cells from oxidative stress induced apoptosis by modulating ROS and active nitrogen species (RNS) and promoting O2 release. In addition, Fe2-NCs restores mitochondrial function by inhibiting NOX4 expression, improving ATP production, and normalizing COXIV levels. In an in-vivo OA model, the Fe2-NCs can reduce the expression of a pro-inflammatory medium COX-2 through an NF-kappa B signal channel, inhibit the up-regulation of MMP-13 and delay the degradation of type II collagen. The invention provides a new theoretical framework and methodological approach for the treatment of osteoarthritis, and has important clinical and scientific significance.

A preparation method of a high-activity nitrogen-doped carbon-loaded CoRu nano-alloy is used for enhancing pH universal hydrogen evolution, and is characterized by comprising the following steps: dissolving dopamine hydrochloride in an aqueous solution containing H2O2 and CuSO4. 5H2O, and magnetically stirring to form a uniform mixture; and pre-wetting carbon cloth with ethanol, immersing the pre-wetted carbon cloth in the dopamine solution for 10 minutes, taking out the pre-wetted carbon cloth, washing the pre-wetted carbon cloth with deionized water for three times, and carrying out vacuum drying to obtain the polydopamine modified carbon cloth marked as PDA / CC. And immersing the obtained PDA / CC into 20 mL of aqueous solution containing Co (NO3) 2.6 H2O and RuCl3 for 6 hours to realize metal ion adsorption. And washing and drying a sample, and calcining the sample in a tubular furnace at 700 DEG C in an N atmosphere for 2 hours to obtain the self-supporting nitrogen-doped porous carbon-loaded CoRu alloy material which is recorded as CoxRu (at) CN / CC. Through a synthesis strategy based on active ion capture and in-situ carbon thermal reduction, and through construction of a nitrogen-doped carbon cobalt ruthenium alloy nanostructure and a strong metal-carrier synergistic effect, efficient hydrogen overflow and establishment of stable active sites are realized; therefore, the performance bottleneck that high activity and high stability of a traditional electrocatalyst in a wide pH range are difficult to cooperate is broken through.

The invention discloses a nitrogen fixation device and a nitrogen fixation method based on alternating current plasma bilateral electrode discharge. The device adopts a pair of electrodes which are respectively connected with a high-voltage end and a low-voltage end and are arranged at the top of a sealed reaction tank, so that the two electrodes can discharge to the surface of an aqueous solution to form stable double-side discharge plasmas. A metal or metal oxide coating (such as TiO2, Pt, CuO and the like) is deposited on the surface of the discharge end of the electrode through a physical or chemical means, so that the breakdown voltage of liquid phase discharge can be reduced, the heat loss caused by excessive discharge is inhibited, and the energy utilization efficiency is improved. In the reaction process, mixed gas containing nitrogen serves as a gas source, nitrogen-containing products such as NH4 < + >, NO2 <-> and NO3 <-> are generated in an aqueous solution under the action of active nitrogen-oxygen groups generated by discharging, and the nitrogen-containing products are collected through reaction liquid and tail gas absorption liquid respectively. The device is simple in structure, the raw materials are easy to obtain, the discharge stability is excellent, the nitrogen fixation energy consumption is remarkably reduced through the synergistic effect of double-side discharge and an electrode surface coating, the nitrogen fixation yield is increased, and the device is suitable for distributed, miniaturized or green nitrogen fixation scenes.

The invention discloses a preparation method of a nano-enzyme preparation as well as a product and application of the nano-enzyme preparation. The synthesis method of the nano-enzyme preparation comprises the following steps: mixing a transmembrane protein solution and a solution containing one or more nano-enzymes to prepare the nano-enzyme preparation. The nano-enzyme can target a disease site, and on one hand, the nano-enzyme removes active oxygen and active nitrogen species on the disease site; on the other hand, the nano-enzyme can be combined with cytokines of disease parts, the promotion effect of the cytokines on diseases is inhibited, and the effect of preventing and treating colitis and colitis-related colon cancer diseases is achieved. The nano-enzyme developed by the invention not only can relieve oxidative stress of diseases, but also can reduce the pro-inflammatory and tumor-promoting effects of cytokines, and can effectively treat colitis-related colon cancer caused by deterioration of colitis.

The invention discloses an anti-aging ganoderma lucidum polysaccharide-milk composition and a preparation method and application thereof.The preparation method includes the steps that ganoderma lucidum sporocarp serves as a raw material, after superfine pretreatment is conducted, ganoderma lucidum polysaccharide is extracted in a free radical mediation mode, the polysaccharide yield is effectively increased, and the activity of the polysaccharide is effectively improved; and then active oxygen free radicals (. OH) and active nitrogen free radicals (DPPH) are respectively used as indexes to preferably select the ganoderma lucidum polysaccharide-milk composition with the optimal synergistic interaction ratio, so that the antioxidant activity of the ganoderma lucidum polysaccharide is improved. The ganoderma lucidum polysaccharide-milk composition preferably selected by the method disclosed by the invention not only has the nutritional values of polysaccharide and milk, but also synergistically enhances free radical scavenging, oxidative stress resistance and aging resistance, so that high-quality utilization of ganoderma lucidum and milk is realized.

The application relates to the field of active nitrogen testing, and discloses a double-flow reactor experimental device for measuring active nitrogen emission and reaction rate, which comprises a reaction mechanism and an irradiation mechanism, the reaction mechanism comprises a first reactor, the outer surface of the first reactor is provided with a constant-temperature water layer, a second reactor is connected with the first reactor through a first connecting pipe, an ozone analyzer is installed on the first connecting pipe, and two dryers are installed on the first connecting pipe; the constant-temperature water layer outside the first reactor in the reaction mechanism can stably control the temperature and store soil samples; the second reactor is connected with the first reactor through the first connecting pipe and is used for particulate matter film samples; the ozone analyzer, an NOx analyzer and the dryers on the first connecting pipe can synchronously detect the concentrations of related gases, and the dryers can eliminate water vapor interference; the double-flow reactor experimental device solves the problem of measuring key parameters of active nitrogen under the background of farmland nitrogen application and nitrate pollution in urban groups, and has the advantages of synchronous analysis of multiple parameters, accurate simulation of environmental conditions, low-interference detection and the like.

The invention discloses a process for strengthening flotation of cuprite through nitrogen plasma surface reconstruction, which comprises the following steps of: crushing high-calcium and high-silicon cuprite, performing dry ball milling, and screening to obtain cuprite powder; the cuprite powder is evenly placed in a plasma reaction chamber, nitrogen is introduced, and high-activity nitrogen plasma selectively acts on the surface of cuprite; pulp mixing and sulfuration treatment: adding ultrapure water into the cuprite powder, uniformly stirring, then adjusting the pH value of the pulp, and then carrying out sulfuration treatment; and flotation separation and product collection are conducted, specifically, a collecting agent and a foaming agent are sequentially added into the cuprite ore pulp, flotation operation is conducted, and efficient separation of cuprite and gangue minerals is achieved. According to the method, selective surface reconstruction is conducted on the cuprite powder through the nitrogen plasma, the floatability difference between the cuprite and gangue minerals is enlarged, targeted strengthening of the vulcanization reaction activity and the adsorption capacity of the collecting agent is achieved, and the cuprite vulcanization flotation recovery rate and the concentrate Cu grade are improved.

This invention discloses a solution for inhibiting keloids and its preparation method. Physiological saline is treated with low-temperature atmospheric pressure plasma (CAP) to become activated saline. The activated saline contains a large amount of reactive oxygen species and reactive nitrogen species. After injection into the body, its active ingredients induce disulfide death in fibroblasts derived from keloids, thereby inhibiting keloid formation. Compared with existing methods for inhibiting keloids, this application has several unique advantages. First, the effect and degree of CAP activation on fibroblast life and death are dose-dependent, allowing for precise control of the effect. Second, the full spectrum of active species generated by CAP can synergistically act on multiple biological targets, reducing the risk of recurrence. Third, CAP is administered through the process of generating an activated solution from a liquid medium, enabling non-invasive or minimally invasive drug delivery and greatly reducing the risk of systemic toxicity. Finally, CAP technology avoids complex biological agent preparation processes, making it simpler to operate and lower in cost. This invention fills the gap in research on low-temperature atmospheric pressure plasma inhibition of keloids.

The invention belongs to the technical field of livestock and poultry manure management and utilization, and provides a method for realizing emission reduction synergy of production of padding, greenhouse gas and active nitrogen gas through rapid and safe fermentation of cow dung residues under a cold condition, and a heating plate is arranged at the bottom of a pile body to realize heating of cold air output from an aeration pipe at the bottom; and in combination with the ascending flow of the air flow in the pile body, the whole large pile body at the upper part can be effectively heated, and the high-temperature period lasts until the fermentation is finished, so that a good fermentation effect is achieved. Start-stop feedback control of the heating plate is realized by monitoring the temperature of the pile body, so that the energy consumption is effectively reduced, and the cost is greatly reduced. The method has the synergistic effects of promoting efficient and safe fermentation of excrement to produce padding and reducing emission of harmful gases in the environment under the cold condition in winter, is simple to operate, realizes efficient value-added utilization of wastes, and has important value and significance for solving the practical problems of excrement treatment and resource utilization in dairy farms.

The invention provides an open type in-situ deodorization system and method for MOF-DBD synergistic active species release and application, and the system comprises a DBD active species generation unit which is used for in-situ release of oxygen free radicals, hydroxyl free radicals, ozone and active nitrogen oxides in an open air environment and preliminary oxidation of ammonia gas, hydrogen sulfide and volatile organic compounds; and the MOF light-oxygen catalysis unit is arranged at the downstream or adjacent area of the DBD active species generation unit in an open manner and is used for carrying out catalytic decomposition on byproducts generated by the DBD active species generation unit under the action of light and further converting the byproducts into harmless or high-reactivity oxide species. The device can efficiently degrade ammonia gas, hydrogen sulfide and volatile organic compounds generated in livestock and poultry breeding and other scenes, has the advantages of high removal efficiency, low energy consumption, long material service life and stable operation, and is suitable for tail end deodorization and industrial waste gas treatment of farms.

The application belongs to the technical field of nanobubble hydrate preparation, and discloses a multi-field coupling ozone and active particle hydrate generating device, which comprises: a main machine, an inner cavity of which comprises an electrolysis area and an ionization area; an ultrasonic generator, which is installed to the main machine and acts on the inner cavity; a venturi pipe, an outlet of which is connected to the electrolysis area of the main machine to feed the micro-nanobubble water formed by mixing air and water into the electrolysis area; and a water outlet pipe, an inlet of which is connected to the ionization area of the main machine. The electrolysis area and the ionization area are horizontally arranged and are separated by an electrode partition. In summary, the device generates hydrates containing strong oxidizing substances such as ozone, active oxygen, active nitrogen and free radicals through the multi-field coupling effects of venturi gas-liquid mixing, electrolytic air floatation pretreatment, ultrasonic enhanced bubble splitting and triggered ionization electric field plasma waterfall, and can also effectively improve the number and stability of ozone nanobubbles in the hydrates.

This invention relates to the field of biomedical antibacterial nanomaterials technology, specifically to an L-arginine-functionalized TiO2. 2‑x Preparation method and application of MXene composite nanomaterials. The preparation method of this invention includes: preparing Ti3C2T using the LiF / HCl in-situ etching method. x MXene dispersion; Ti3C2T x MXene is mixed with glycerol and then subjected to a hydrothermal reaction, forming TiO2 in situ on the MXene surface. 2‑x TiO 2‑x -MXene; further functionalization with L-arginine yields LA@TiO 2‑x -MXene composite nanomaterials. The materials of this invention exhibit excellent near-infrared photothermal response and ultrasonic response acoustic dynamic activity, and can generate NO and ONOO under ultrasonic stimulation. ‑ The materials of this invention can be used to prepare anti-MRSA antibacterial materials, anti-biofilm materials, antibacterial dressings, or antibacterial coatings for medical device surfaces, exhibiting synergistic antibacterial effects of photothermal, acoustic dynamic, and active nitrogen species.

The application discloses a nitrogen oxide treatment agent and a preparation process thereof, and relates to the technical field of air pollution treatment and environmental protection. The composite alkaline component is composed of a sodium-based compound and an activator; the nitrogen-containing reducing agent is a pyrolytic nitrogen-containing organic matter; the stabilizer system is composed of a thickening agent and a chelating agent; and the solvent is deionized water. The composite alkaline component is used for providing an alkaline environment, assisting in oxidizing low-valence nitrogen oxides, and accelerating the decomposition of nitrogen oxides. x The nitrogen-containing reducing agent generates active nitrogen species under alkaline conditions, and the active nitrogen species and NO x react to generate nitrogen and water through a reduction reaction. In the application, the sodium-based compound, the activator and the pyrolytic nitrogen-containing organic matter realize the efficient removal of NO The application solves the technical problems of high treatment cost and low efficiency in current environmental pollution, and does not need to be catalyzed by an expensive catalyst.

The invention relates to a liquid plasma activating treatment method and device. The method comprises the steps that liquid to be treated is sealed in a container, gas containing oxygen and nitrogen is introduced, the liquid level is controlled to be located below the plasma discharge structure by adjusting the limiting stopper, and activation treatment is conducted by means of plasma generated through dielectric barrier discharge. The device adopts a multi-accommodating-cavity parallel processing structure, is equipped with a limiter to accurately adjust the liquid level position, and integrates a power supply module, a control module and a temperature control system to realize high-flux and non-contact activation. The method is suitable for treating platelet-rich plasma, promotes platelet to release growth factors by increasing the concentration of active oxygen and active nitrogen components, and enhances the biological activity of the platelet. According to the scheme, the problems of complicated operation, pollution risk and low automation degree in the prior art are solved.

The present invention relates to a plasma filter for purifying contaminated air in the atmosphere, comprising a housing having a fluid flow path formed in the direction of air flow, a charging section disposed at the inlet side of the fluid flow path, a dust collection section including at least one dust collection electrode disposed spaced apart from the charging section and extending to the outlet side of the housing while being disposed in a direction parallel to the fluid flow path, and at least one surface dielectric barrier discharge source, wherein pathogens are charged in the charging section, a DC high voltage is applied to at least one collecting electrode to induce the charged pathogens to the surface dielectric barrier discharge source or the surface of the collecting electrode, an AC or pulse voltage is applied to the surface of the surface dielectric barrier discharge source to generate a surface dielectric barrier discharge plasma, and pathogens are disinfected by the generated plasma and / or active oxygen species or active nitrogen species generated by the plasma.

The application discloses a kind of preparation methods of plasma activated water based on three-chamber coupling and intelligent regulation and control.The method includes electrolytic unit, discharge unit, mixing unit and intelligent control unit, wherein the electrolytic unit includes cathode chamber and anode chamber, ion exchange membrane is arranged between the two, and corresponding anode effluent and cathode effluent are generated through cathode oxygen reduction path or anode water oxidation path;Discharge unit generates discharge effluent containing active nitrogen species by plasma discharge method.Through mixing and intelligent control unit, the mixing ratio and mixing order of discharge effluent, cathode effluent and anode effluent generated by different paths are intelligently controlled, so as to obtain plasma activated water with precisely customized physicochemical properties, to be suitable for sterilization and disinfection, agricultural application and use scenarios with higher environmental compatibility requirements.

The invention discloses network enhanced fluorescent composite fireproof glass and a preparation method thereof. The preparation method comprises the following steps: S1, preparing reactive nitrogen-doped fluorescent carbon dot dispersion liquid of which the surface is simultaneously bonded with amino and silicon hydroxyl from a carbon source, a nitrogen source and a silane coupling agent through a hydrothermal reaction; s2, mixing and concentrating alkaline silica sol and polyol, adding the carbon dot dispersion liquid and an alkaline activator for reaction, and performing vacuum defoaming to obtain groutable intermediate liquid; s3, grouting and curing to obtain the network enhanced fluorescent composite fireproof glass. Through in-situ synergistic reaction of a carbon source, a nitrogen source and a silane coupling agent, amino and silicon hydroxyl are bonded to the surfaces of the carbon dots at the same time, and the carbon dots are embedded into a silicon-oxygen network skeleton in a covalent bond mode through copolycondensation in the curing process to become a network structure constituent part. Experiments prove that the anti-counterfeiting function and network enhancement are coordinated, the DTG main peak temperature is increased by 30 DEG C, the fire endurance is improved, and the light transmittance is kept at 88% or above.

This invention provides a magnesium alloy, its preparation method, and its applications. The magnesium alloy comprises a magnesium alloy body and a peroxide coating covering the surface of the magnesium alloy body. A protein carrier is adsorbed on the surface of the peroxide coating, and a NO donor is loaded onto the surface of the protein carrier. The magnesium alloy body can generate hydrogen gas in situ within the acidic tumor microenvironment, downregulating the expression of heat shock proteins in tumor cells, making tumor cells sensitive to temperature, and killing tumor cells under a low-intensity alternating magnetic field. Simultaneously, the peroxide coating stimulates the release of NO from the NO donor in the acidic tumor microenvironment, while the magnesium alloy body promotes the production of heat-activated oxygen substances inside cancer cells, which further react with NO to produce more toxic reactive nitrogen substances, achieving further killing of tumor cells.