92results about How to "Inhibits biofilm formation" patented technology

A urinary catheter clip-on device applies surface acoustic waves of Rayleigh-Lamb and/or Love type to a urinary catheter for preventing biofilms on the catheter surfaces. The bacteria is forced to move relative to the vibrating catheter surface. The amplitudes of bacteria vibrations are in nanometer range. The relative motion of bacteria results in bacteria quorum sensing, and disrupts the bacteria attachment process. The method is preventive as surface acoustic waves create low acoustic energy and bacteria is not killed.

The present invention provides a gallium-containing composition for coating/impregnating a device or device surface to prevent biofilm growth formation. The present invention also provides a method of preventing or inhibiting biofilm growth formation. The present invention also provides methods for killing established biofilms.

Disclosed herein are methodologies and compositions for coating materials, which can be used in a variety of biological applications.

There is disclosed a method for disrupting biofilm and for inhibiting biofilm formation in an aqueous environment that comprises contacting said environment with an effective amount of D-tagatose.

An implantable catheter is provided that may be disinfected without removal from the body of a patient, using an electrochemical method to generate an electric field on the catheter surface and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter and a voltage source that is operably connected to electrodes on or embedded in the exterior and optionally the interior catheter surface. Methods are also provided for disinfecting the implantable catheter in vivo and for detecting or confirming the presence of a pathogenic biofilm thereon.

A high-voltage capacitive electrostatic device is used to improve the performance of membrane-separation processes, particularly reverse-osmosis units, wherein species of a given ionic polarity are separated from water. The device is immersed in the water flowing across the membranes and is operated continuously at very high voltages, preferably greater than 30,000 volts DC. The charge on the wetted surface of the suspended particles is altered by the electrostatic field so generated and is found to reduce biofilm formation, thereby materially enhancing the performance of the membrane-separation system. The application of high-voltage electrostatic fields is also found to reduce corrosion of metallic surfaces in the system.

An anti-microbial composition, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sufonyl Methane; MSM) is provided. Together, the combination of the two substances unexpectedly and beneficially inhibits bacterial or fungal biofilms when administered to an area of microbial infection. Preferred formulations include spray, lotion, solution, gel, cream, ointment, soap, deodorant, surgical rinse, or dental rinse.

The present invention relates to surface modification of reverse osmosis membranes to introduce antifouling properties without compromising the separation properties of the original membranes. This approach utilizes: providing a coated membrane surface having enhanced hydrophilic characteristics that prevents the biofoulants from settling; have a surface that consists of hydrophilic brushes that unsettle any biofoulants that get through; and having antimicrobial ions present in the membrane coatings and able to remove or minimize any remaining biofoulants without leaching into the permeate. These coatings are made using dendritic polymers such as hyperbranched polymers or dendrimers.

This disclosure relates to medical devices incorporating one or more cationic steroidal antimicrobials (CSAs). The CSAs are incorporated into the medical devices to provide effective antimicrobial, anti-inflammatory, and/or tissue-healing properties. A medical device includes a component formed from a polymeric material. One or more CSA compounds are mixed with the polymeric material so that the one or more CSA compounds are incorporated into the structure of the medical device as formed from the polymeric material. A medical device can additionally or alternatively include a lubricious coating containing one or more CSA compounds.

A method of preventing biofilm formation in an environment including the steps of administering to the environment an effective amount of a peptide having the amino acid sequence NH2-lys-lys-val-val-phe-lys-val-lys-phe-lys-CONH2. The method is useful in preventing the formation of biofilms in various environments including a home, workplace, laboratory, industrial environment, aquatic environment, animal body or human body. A method of inhibiting the growth of oral microorganisms including the steps of administering to an oral environment an effective amount of a peptide having the amino acid sequence NH2-lys-lys-val-val-phe-lys-val-lys-phe-lys-CONH2.

The invention relates to a soft-tissue implant for use in the medical field which has an antibacterial effect. The soft-tissue implant, which may for example be a breast implant, has at least one antibiotic substance bound to the implant surface in first and second configurations that release the antibiotic substance, after implanting in an animal body, at short term and long term release rates. The first and second configurations are each present at one or more common surface locations. The soft-tissue implant has an antibacterial effect that prevents or reduces the deposition of bacteria and the formation of bacteria-containing biofilms.

The water battery device has a sterilizing unit composed of a non-noble metal body and a noble metal body that are overlapped coaxially via an interval keeping member. The sterilizing unit is disposed in a passing water or flowing water or immersed in a stored water. Then, a battery action is generated via the water at a uniform clearance space between the non-noble metal body and the noble metal body. Thereby, metal ions are dissolved in a complete ionization state from the non-noble metal body, thereby giving sterilization effect to the water. A container has a container structure that generates an electric current in the water between the non-noble metal body and the noble metal body and that maintains an oxygen concentration in the water required to continually produce the battery action water. Moreover, with the container structure, the concentration of the battery action water produced between the non-noble metal body and the noble metal body becomes not less than a predetermined concentration at which an oxide film or biofilm is formed on a facing surface of the non-noble metal body. Thus, the container structure surrounds the non-noble metal body and the noble metal body to keep the concentration of the battery action water at the concentration not less than the predetermined concentration.

A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the growth of these bacteria, are provided. A biofilm formation inhibitor having an effective amount of catechin for inhibiting biofilm formation and a carrier that is suitable for adhesion of said catechin to a treatment device to be placed in the living body, are provided.

Disclosed is a container having a novel structure for storing contact lenses by which biofilm formation can be prevented at a high cost efficiency and from which lenses can be easily taken out. A container for storing contact lenses wherein the inner face of a dish-shaped storage chamber in a case is entirely made of a radius of curvature which is a smooth face with no irregularity and shows a continuous change, the inner face entirely comprises a smooth face with a surface roughness of 60 nm or less, and the solution capacity of the dish-shaped storage chamber is set to 3.8 mL or more.

The present invention relates to a method including reacting a solution of a salt of a biocidal metal with an active layer of water purification membrane, discarding the biocidal metal salt solution such that a thin layer of the biocidal metal salt solution remains on the membrane surface, reacting a reducing agent solution with the active layer of the membrane and the thin layer of the biocidal metal salt solution thereby forming a biocidal metal nanoparticle-modified membrane, removing the reducing agent solution, and rinsing the biocidal metal nanoparticle-modified membrane.

The disclosure relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.