23results about How to "Avoid irritation" patented technology

The invention discloses a natural vegetable oil composition as well as a preparation method and application thereof. The natural vegetable oil composition comprises sunflower seed oil, simmondsia chinensis seed oil, grape seed oil and camellia seed oil. The feeding mass ratio of the sunflower seed oil to the simmondsia chinensis seed oil to the grape seed oil to the camellia seed oil is 1: (0.5-1.5): (0.5-1.5): (0.5-1.5); the components are uniformly mixed during preparation, practice shows that the combination of the four natural plant-derived oils has an excellent moisturizing effect and a skin repairing effect and has a remarkably better and more balanced effect compared with a single or partial combination of the four natural plant-derived oils, and particularly, the remarkable moisturizing and skin repairing effects can be obtained only by a small addition amount; the composition is beneficial to addition and use in cosmetics, does not need to adopt excessive emulsifiers for additional emulsification and dispersion, is beneficial to reduction of irritation brought by the emulsifiers, and is good in use experience.

The invention discloses a scalp oil control composition and a preparation method and application thereof, and belongs to the technical field of daily chemical product preparation, the scalp oil control composition comprises, by mass, 20-50 parts of a component A, 0.1-5 parts of menthol, 0.05-1 part of zinc gluconate, 0.3-1 part of a preservative, 0.1-0.6 part of a pH regulator and 42.4-79.45 parts of water, the component A is obtained by mixing a compound extract of white tea, cedar and spiraea ulmus with polyhydric alcohol, performing low-temperature centrifugal separation and filtering. According to the invention, the surfactant-containing water solvent is adopted to assist ultrasonic extraction of natural functional components of plants, so that the problem of abnormal secretion of scalp grease caused by solvent residue is avoided, no extraction solvent residue is realized, and the operation is simple; meanwhile, extracts of the white tea, the cedar and the spiraea inflorescens are reasonably matched and supplement with other auxiliary components to synergistically achieve the effects of regulating scalp grease secretion, inhibiting inflammatory factors and maintaining scalp micro-ecology, so that the scalp oil control effect is achieved, and the composition can be widely applied to scalp oil control daily chemical products.

The invention relates to the technical field of collagen dressings, in particular to a moisturizing and repairing collagen dressing and a preparation method thereof. The moisturizing and repairing collagen dressing is prepared from the following components in parts by mass: 10 to 30 parts of recombinant human fibronectin, 10 to 20 parts of recombinant collagen, 5 to 15 parts of beta-glucan, 5 to 10 parts of compound hexanediol, 40 to 50 parts of carbomer, 5 to 15 parts of a flavoring agent, 80 to 120 parts of purified water, 10 to 30 parts of a modified recombinant human III type collagen solution and 10 to 20 parts of a modified chitosan solution. The recombinant human fibronectin disclosed by the invention can be deposited at an injured part to form a blood clot, so that the aim of stopping bleeding is fulfilled, and the subcutaneous tissue is protected; the recombinant collagen has high biological activity and can inhibit inflammation and improve the conditions of pachulosis, damage and the like of the skin; the beta-glucan can generate cytokines, promote healing of skin with laser-dependent dermatitis or barrier damage, and realize anti-allergic and anti-inflammatory effects.

The invention discloses a hair loss prevention and hair growth composition, a preparation method thereof, and a hair care cosmetic containing the hair loss prevention and hair growth composition, which is composed of the following components: 1-2 parts of ginger root extract; 1-2 parts of Polygonum multiflorum extract; 2.58-8.3 parts of skin auxiliary conditioner; 0.56-2.1 parts of hair auxiliary conditioner; 0.1-2 parts of preservative; 5-15 parts of moisturizer; 70-85 parts of water. The above composition can effectively improve the hair microenvironment, inhibit sebum secretion, and prolong the hair survival cycle through the cooperation of the skin auxiliary conditioner and the ginger root extract. While comprehensively preventing hair loss, the hair auxiliary conditioner and the Polygonum multiflorum extract are used to regulate the blood supply of the key parts of the hair follicle cycle growth, enhance the vitality of the hair, and strengthen the hair roots, thereby achieving a comprehensive solution to various problems such as seborrheic alopecia, neurotic alopecia, diffuse alopecia, and nutritional alopecia.

The utility model discloses a calcaneus locking plate and a calcaneus fixing device, and belongs to the technical field of medical instruments.The calcaneus locking plate comprises a plurality of locking parts, the multiple locking parts are arranged at intervals, and the locking parts are provided with locking holes; each connecting part is arranged between the at least two locking parts and is respectively connected with the at least two locking parts; wherein the locking hole of at least one locking part is a first locking hole, the first locking hole is used for connecting the locking part with the sustentaculum tali, and the first locking hole is provided with a first central axis AA '; the locking part has a connecting state of being connected to the sustentaculum tali, in the connecting state, a first included angle alpha is formed between the first central axis AA'and the coronal plane YY ', a second included angle beta is formed between the first central axis AA' and the cross section XX ', alpha is larger than or equal to 14 degrees and smaller than or equal to 18 degrees, and beta is larger than or equal to 3 degrees and smaller than or equal to 6 degrees. According to the calcaneus locking plate, the sustentaculum tali can be accurately positioned through the first locking holes in clinic, the locking screws are accurately guided, the accuracy of connecting the sustentaculum tali is improved, and the operation efficiency is improved.

This invention provides an internal fixation device for cancellous bone, belonging to the field of medical device technology. It includes a fixation plate with a plurality of screw holes and positioning holes arranged in a linear array on its top outer wall; and a guide assembly connected to the fixation plate, used to guide the hollow self-drilling screws. By incorporating the guide assembly, this invention not only guides the hollow self-drilling screws, preventing them from deviating from their pre-operatively assessed position during insertion, thus affecting their fixation effect on the fracture site, but also holds the screws during the guiding process, preventing the screw head from tilting and protruding, which could cause skin irritation and affect postoperative recovery.

The invention relates to the field of A61K8 / 18, in particular to a skin care target-based micro-ecological composition with soothing and repairing effects, which is at least prepared from the following raw materials in parts by weight: 1 to 40 parts of prebiotics, 0 to 20 parts of probiotics, 0.1 to 3 parts of auxiliaries and 50 to 100 parts of solvent, wherein the prebiotics at least comprise at least one of dextran, ribose, inulin and ectoine, the microecological balance of the skin is effectively regulated, meanwhile, the effects of repairing the skin barrier, relieving redness, stabbing pain and itching, resisting oxidation and the like are achieved, and the use requirements of the sensitive skin are better met.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.

The invention relates to the technical field of eye care products, in particular to a gel eye patch for treating xerophthalmia and a preparation method and application thereof.The preparation method comprises the steps that a gelatin solution, a carboxymethyl chitosan solution and a borneol solution are mixed, shaped and soaked, soaked gel is obtained, a gel matrix is placed on the soaked gel, the gel eye patch is obtained after soaking, and the gel eye patch is used for treating xerophthalmia. And soaking in a sodium sulfate solution for 30 minutes, and the mass percentage of the sodium sulfate solution is 15%. When the gel eye pad acts on the periphery of the eye, the borneol is combined with the transient receptor potential cation channel subfamily M member 8 on the ocular surface, so that the lacrimation is stimulated by activating the cold-sensitive primary afferent neuron. A layer of gel is added on the eye pad to prepare the double-layer gel eye pad. And the upper gel can be physically isolated, so that the irritation of the volatility of borneol to eyes is avoided. The traditional Chinese medicine composition can safely, quickly and effectively promote tear secretion of a patient suffering from the xerophthalmia, and irritation is effectively avoided while the xerophthalmia is treated.

The invention relates to a natural plant extract anti-aging and firming composition as well as a preparation method and application thereof. The natural plant-extracted anti-aging and firming composition is prepared from cyathea spinulosa leaf extract, pinus sibirica and arnica montana extract, abelmoschus esculentus extract, tetrahydropiperine, centella asiatica extract and cichorium intybus extract. Specifically, the composition is prepared from the following components in parts by weight: 10 to 20 parts of cyathea spinulosa leaf extract, 8 to 18 parts of pinus sibirica arnica extract, 5 to 20 parts of chrysanthemum indicum extract, 1 to 3 parts of tetrahydropiperine, 6 to 10 parts of centella asiatica extract and 6 to 10 parts of chicory extract. The anti-aging and skin-tightening composition provided by the invention not only provides a scientific and effective skin care solution, but also pays attention to the naturalness and safety of the product, and brings healthier and more natural skin care experience to consumers.

This invention discloses a detergent for removing milky odor and its preparation method, comprising the following components by weight percentage: 6-10 parts nutmeg extract, 2-3 parts phospholipase, 2-3 parts lipase, 3-5 parts α-amylase, 3-6 parts natural citric acid, 1-2 parts cyclodextrin, 0.5-1.5 parts dipotassium glycyrrhizate, 2-3 parts C8-16 alkyl glucoside, 2-3 parts C10-16 sodium polyoxyethylene ether sulfate, 1-2 parts aminopropylamine cocoate, and 1-2 parts sodium C10-16 alkylbenzene sulfonate. Through the synergistic effect of specific enzyme preparations (phospholipase, lipase, and α-amylase), it efficiently decomposes residual lipids and proteins in milk stains, thus fundamentally eliminating the milky odor. Simultaneously, the cyclodextrin encapsulation technology, natural citric acid, and green tea polyphenol extract further adsorb and neutralize odor molecules, achieving multiple effects of deodorization, anti-oxidation, and antibacterial properties.

The application discloses a natural plant oil composition and a preparation method and application thereof, and belongs to the field of cosmetics. The natural plant oil composition comprises sunflower seed oil, jojoba seed oil, grape seed oil and camellia seed oil. The mass ratio of the sunflower seed oil, the jojoba seed oil, the grape seed oil and the camellia seed oil is 1:0.5-1.5:0.5-1.5:0.5-1.5. The components are mixed uniformly during preparation. Practice shows that the combination of the four natural plant oils has excellent moisturizing effect and skin repair effect. Compared with the single or partial combination of the four natural plant oils, the combination has a more optimal and balanced effect. In particular, the moisturizing and skin repair effect can be significantly improved with a small amount of the natural plant oil composition, and the natural plant oil composition is beneficial to be added and used in cosmetics, does not need to be additionally emulsified and dispersed by using too much emulsifier, is beneficial to reduce the irritation caused by the emulsifier, and has a good use experience.

The application discloses a composite biomaterial and a preparation method and application thereof, and comprises the following steps: respectively pretreating porcine peritoneum and porcine fascia lata to obtain dried porcine peritoneum and dried porcine fascia lata; mixing the dried porcine peritoneum and the dried porcine fascia lata, adding a buffer solution to homogenate to obtain a composite homogenate solution; adjusting the pH of the composite homogenate solution to be alkaline, adding trypsin to perform first-stage enzymolysis; adjusting the pH of the composite homogenate solution to be acidic, adding pepsin to perform second-stage enzymolysis; performing salting-out and centrifugation on the composite homogenate solution after the second-stage enzymolysis, collecting the precipitate, sterilizing the precipitate, and obtaining the composite biomaterial.

The invention discloses a clavicle fracture intramedullary fixing nail and a clavicle fracture intramedullary fixing system.The clavicle fracture intramedullary fixing nail can be implanted into a clavicle through an external bone drill and comprises a head section and a tail section, and the head section comprises a thread structure extending from the edge of the first end of a nail body of the clavicle fracture intramedullary fixing nail to the center; the tail section comprises a thread structure extending from the edge of the second end of the nail body of the intramedullary fixing nail for clavicle fracture to the center, the head section and the tail section have the same rotation direction of the thread structure, and the thread pitch of the head section is larger than that of the tail section. The end portions of the head section and the tail section are clamped through a bone drill, and the head section and the tail section are meshed with cortical bones at the edges of the two ends of the clavicle through a thread structure. The intramedullary fixation system for the clavicle fracture comprises an incision construction unit, a clavicle reduction and fixation unit, a patient clavicle imaging unit and an incision suture unit. The variable-pitch thread structures at the two ends of the intramedullary fixing nail for the clavicle fracture are meshed with cortical bones to achieve the pressurization effect, meanwhile, loosening after meshing is avoided, and the fracture clavicle can be firmly maintained to be reset.

The invention discloses an immunopotentiator for improving the anti-stress capability of aquatic animals and a preparation method of the immunopotentiator. The immunopotentiator for improving the anti-stress capability of the aquatic animals is prepared from the following raw materials: spirulina powder; whey protein; a beta-glucan; glucosamine sulfate; potassium citrate; fish oil powder; algal polysaccharides; a nucleotide mixture; coating particles with vitamin C; a trace element chelate; according to the immunopotentiator capable of improving the anti-stress capacity of the aquatic animals and the preparation method of the immunopotentiator, the spirulina powder, the beta-glucan, the glucosamine sulfate and the nucleotide mixture are compounded, the anti-stress capacity of the aquatic animals is remarkably improved through the synergistic effect, and the survival rate of the aquatic animals is increased to 91% under the stress condition; the vitamin C coated particles, the fish oil powder and the algal polysaccharides are added, so that the antioxidant enzyme activity is effectively improved, the oxidation resistance of an immune system and the resistance to pathogenic bacteria are enhanced, and a remarkable immune enhancement effect is shown.

The invention provides a traditional Chinese medicine hot compress physical therapy device good in attaching performance, and belongs to the technical field of traditional Chinese medicine hot compress, the traditional Chinese medicine hot compress physical therapy device good in attaching performance comprises an attaching mechanism, a medicine mist generator, a skin type collecting system and a control heating element, fixing bandages are arranged on the two sides of the special-shaped protection band structure respectively and used for fixing the position of the special-shaped protection band structure, a medicine outlet cavity is formed in the inner side of the special-shaped protection band structure, a plurality of sets of air holes are formed in the surface of the special-shaped protection band structure, the medicine outlet cavity is connected with the medicine mist generator through a medicine feeding pipe, and the medicine mist generator is connected with the medicine mist generator. The skin type acquisition system comprises a skin sensor module and a control system, and the skin sensor module is arranged on the inner side of the special-shaped protecting band structure; the problem of irritation caused by traditional Chinese medicine hot compress corresponding to different skin types in a traditional single output mode can be avoided, and the balance and stability of traditional Chinese medicine hot compress physiotherapy are improved.

The invention relates to the technical field of soil loosening, and discloses a soil loosening device matched with a mini-tiller, which comprises a side plate, the end part of the side plate is connected with the mini-tiller, one end of the side plate close to the mini-tiller is rotatably connected with a main shaft, two ends of the main shaft are provided with walking wheels, one end of the side plate far away from the main shaft is rotatably connected with a rotating shaft, and the rotating shaft and the main shaft synchronously rotate. The device further comprises a soil loosening mechanism and a soil digging mechanism. The soil loosening mechanism is arranged on the side, close to the ground, of the side plate and comprises a cutter shaft rotationally connected with the side plate, and a plurality of soil loosening teeth are arranged in the middle of the cutter shaft; the soil digging mechanism comprises a cross rod fixedly connected with the side plates and a swing arm which deflects in a reciprocating mode with the cross rod as the center, and a rear throwing shovel is arranged at the end, close to the walking wheels, of the swing arm. The back throwing shovel which swings back and forth is additionally arranged on the front side of the advancing direction of the soil loosening teeth, the operation mode of digging first and then smashing is formed, and the problems that traditional soil loosening teeth are difficult to penetrate into hard soil and slip and idle are effectively solved.

The invention relates to the technical field of functional gel preparation, in particular to a preparation method of functional gel. The functional gel provided by the invention is prepared by the following steps: mixing 50 parts of water at 50 DEG C, 11 parts of carbomer and 5 parts of xanthan gum, and stirring at 150rpm for 10 minutes to obtain a material 1; mixing the material 1 with 6 parts of isopropyl palmitate, and stirring at 200rpm for 20min to obtain a material 2; and cooling the material 2 to 23 DEG C, mixing the material 2 with 25 parts of ethanol with the volume concentration of 80%, 13 parts of n-butyl alcohol with the volume concentration of 50%, 14 parts of glycerol and 3 parts of propyl hydroxybenzoate, stirring for 20 minutes at the speed of 200rpm, and regulating the pH to 5.4 by using a pH regulator sodium carbonate to obtain the functional gel. The functional gel prepared by the invention does not contain any medicine component, is safe and non-irritant in the use process, has an excellent treatment effect on male sexual dysfunction, and has a use effect equivalent to that of medicines in the prior art.

The invention provides a preparation method of buracametacin, which comprises the following steps: dissolving tetrahydro-N, N-dimethyl-5-oxo-2, 2-diphenyl-3-furanformamide with tetrahydrofuran, adding sodium borohydride and a boron trifluoride diethyl etherate complex, and carrying out reflux reaction to obtain the buracametacin.

The utility model relates to a straddle nail with asymmetric arms. The straddle nail comprises a nail beam (1) made of shape memory alloy, a long nail arm (2) and a short nail arm (3), the long nail arm (2) and the short nail arm (3) are arranged at the two ends of the nail beam (1) respectively, the long nail arm (2) and the short nail arm (3) face each other to form an angle, and fixing teeth (4) are arranged on the long nail arm (2) and the short nail arm (3). Compared with the prior art, the screw structure is firm in fixation, is attached to an orthopedic bone surface, is more stable in three-point (or multi-point) clamping, can avoid irritation caused by screw retreating after the screw structure is used, also avoids bone burst caused in the process that the screw structure is screwed into a bone substance, does not need to be measured in an operation, and is convenient to use. And whether the screw is too long to enter the articular surface is not required, and the installation is simple and efficient.

The invention discloses an oxazepam composition, and belongs to the field of pharmaceutical chemicals. The applicant applies a solid dispersion technology to solubilization of oxazepam for the first time, and provides an oxazepam dispersion and appropriate auxiliary materials and a preparation method. Compared with an oxazepam raw material medicine, the solid dispersion technology is adopted, so that the water solubility of oxazepam can be improved, the oral bioavailability is further improved, and meanwhile, the clinical use safety of oxazepam is improved. Compared with other conventional preparations, the tablet containing the oxazepam dispersoid has good physical stability, better dissolution and better bioavailability, and after a stability test is accelerated for 6 months, indexes such as solubility, related substances and the like of the tablet meet quality standard requirements.

The invention relates to the technical field of skin care products, in particular to the field of IPC A61K8, and further relates to whitening and freckle removing face cream and a preparation method thereof. The whitening and freckle-removing mask is prepared from the following raw materials: a whitening and freckle-removing composition, an emollient, a humectant, an emulsifier, a light stabilizer, a preservative, a thickener, essence, EDTA-2Na and water. The whitening and freckle-removing composition at least comprises nicotinamide and a plant extract containing a flavone component. According to the face cream, through the synergistic effect of the nicotinamide, the plant extract containing the flavone component, the resorcinol derivative, the vitamin E and the soothing composition, whitening and freckle removing are achieved from multiple dimensions, and meanwhile the problem of compatibility among the raw materials is solved.

The invention relates to an eye protection instrument based on light response, and belongs to the technical field of medical instruments, the eye protection instrument based on light response comprises a cavity, and a light driving assembly and a medicine carrying assembly which are arranged in the cavity; the light driving assembly comprises an ultraviolet lamp and an infrared lamp which are oppositely arranged up and down in the cavity, and a light response material arranged between the ultraviolet lamp and the infrared lamp; the light response material comprises an ultraviolet light response layer, a flexible middle layer and an infrared light response layer which are sequentially arranged from top to bottom; the medicine carrying assembly is connected with the photoresponse material through the pushing part; the end, connected with the photoresponse material, of the pushing part is lower than the end, connected with the medicine carrying assembly, of the pushing part. The medicine carrying assembly comprises a medicine storage cavity and a medicine carrying microneedle which is arranged on the side wall of the medicine storage cavity and communicates with the medicine storage cavity. According to the eye protection instrument, medicine can be accurately injected into acupuncture points around eyes, and the problems that medicine administration is unstable, the medicine administration efficiency is low, skin is prone to being damaged and the like when medicine is applied to asthenopia at present can be effectively solved.