8results about How to "Avoid irritation" patented technology

This invention provides an internal fixation device for cancellous bone, belonging to the field of medical device technology. It includes a fixation plate with a plurality of screw holes and positioning holes arranged in a linear array on its top outer wall; and a guide assembly connected to the fixation plate, used to guide the hollow self-drilling screws. By incorporating the guide assembly, this invention not only guides the hollow self-drilling screws, preventing them from deviating from their pre-operatively assessed position during insertion, thus affecting their fixation effect on the fracture site, but also holds the screws during the guiding process, preventing the screw head from tilting and protruding, which could cause skin irritation and affect postoperative recovery.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.

This invention discloses a detergent for removing milky odor and its preparation method, comprising the following components by weight percentage: 6-10 parts nutmeg extract, 2-3 parts phospholipase, 2-3 parts lipase, 3-5 parts α-amylase, 3-6 parts natural citric acid, 1-2 parts cyclodextrin, 0.5-1.5 parts dipotassium glycyrrhizate, 2-3 parts C8-16 alkyl glucoside, 2-3 parts C10-16 sodium polyoxyethylene ether sulfate, 1-2 parts aminopropylamine cocoate, and 1-2 parts sodium C10-16 alkylbenzene sulfonate. Through the synergistic effect of specific enzyme preparations (phospholipase, lipase, and α-amylase), it efficiently decomposes residual lipids and proteins in milk stains, thus fundamentally eliminating the milky odor. Simultaneously, the cyclodextrin encapsulation technology, natural citric acid, and green tea polyphenol extract further adsorb and neutralize odor molecules, achieving multiple effects of deodorization, anti-oxidation, and antibacterial properties.

The application discloses a natural plant oil composition and a preparation method and application thereof, and belongs to the field of cosmetics. The natural plant oil composition comprises sunflower seed oil, jojoba seed oil, grape seed oil and camellia seed oil. The mass ratio of the sunflower seed oil, the jojoba seed oil, the grape seed oil and the camellia seed oil is 1:0.5-1.5:0.5-1.5:0.5-1.5. The components are mixed uniformly during preparation. Practice shows that the combination of the four natural plant oils has excellent moisturizing effect and skin repair effect. Compared with the single or partial combination of the four natural plant oils, the combination has a more optimal and balanced effect. In particular, the moisturizing and skin repair effect can be significantly improved with a small amount of the natural plant oil composition, and the natural plant oil composition is beneficial to be added and used in cosmetics, does not need to be additionally emulsified and dispersed by using too much emulsifier, is beneficial to reduce the irritation caused by the emulsifier, and has a good use experience.

The application discloses a composite biomaterial and a preparation method and application thereof, and comprises the following steps: respectively pretreating porcine peritoneum and porcine fascia lata to obtain dried porcine peritoneum and dried porcine fascia lata; mixing the dried porcine peritoneum and the dried porcine fascia lata, adding a buffer solution to homogenate to obtain a composite homogenate solution; adjusting the pH of the composite homogenate solution to be alkaline, adding trypsin to perform first-stage enzymolysis; adjusting the pH of the composite homogenate solution to be acidic, adding pepsin to perform second-stage enzymolysis; performing salting-out and centrifugation on the composite homogenate solution after the second-stage enzymolysis, collecting the precipitate, sterilizing the precipitate, and obtaining the composite biomaterial.

The invention discloses a clavicle fracture intramedullary fixing nail and a clavicle fracture intramedullary fixing system.The clavicle fracture intramedullary fixing nail can be implanted into a clavicle through an external bone drill and comprises a head section and a tail section, and the head section comprises a thread structure extending from the edge of the first end of a nail body of the clavicle fracture intramedullary fixing nail to the center; the tail section comprises a thread structure extending from the edge of the second end of the nail body of the intramedullary fixing nail for clavicle fracture to the center, the head section and the tail section have the same rotation direction of the thread structure, and the thread pitch of the head section is larger than that of the tail section. The end portions of the head section and the tail section are clamped through a bone drill, and the head section and the tail section are meshed with cortical bones at the edges of the two ends of the clavicle through a thread structure. The intramedullary fixation system for the clavicle fracture comprises an incision construction unit, a clavicle reduction and fixation unit, a patient clavicle imaging unit and an incision suture unit. The variable-pitch thread structures at the two ends of the intramedullary fixing nail for the clavicle fracture are meshed with cortical bones to achieve the pressurization effect, meanwhile, loosening after meshing is avoided, and the fracture clavicle can be firmly maintained to be reset.

The invention relates to the technical field of soil loosening, and discloses a soil loosening device matched with a mini-tiller, which comprises a side plate, the end part of the side plate is connected with the mini-tiller, one end of the side plate close to the mini-tiller is rotatably connected with a main shaft, two ends of the main shaft are provided with walking wheels, one end of the side plate far away from the main shaft is rotatably connected with a rotating shaft, and the rotating shaft and the main shaft synchronously rotate. The device further comprises a soil loosening mechanism and a soil digging mechanism. The soil loosening mechanism is arranged on the side, close to the ground, of the side plate and comprises a cutter shaft rotationally connected with the side plate, and a plurality of soil loosening teeth are arranged in the middle of the cutter shaft; the soil digging mechanism comprises a cross rod fixedly connected with the side plates and a swing arm which deflects in a reciprocating mode with the cross rod as the center, and a rear throwing shovel is arranged at the end, close to the walking wheels, of the swing arm. The back throwing shovel which swings back and forth is additionally arranged on the front side of the advancing direction of the soil loosening teeth, the operation mode of digging first and then smashing is formed, and the problems that traditional soil loosening teeth are difficult to penetrate into hard soil and slip and idle are effectively solved.

The invention provides a preparation method of buracametacin, which comprises the following steps: dissolving tetrahydro-N, N-dimethyl-5-oxo-2, 2-diphenyl-3-furanformamide with tetrahydrofuran, adding sodium borohydride and a boron trifluoride diethyl etherate complex, and carrying out reflux reaction to obtain the buracametacin.