The invention provides a production method of five-prevention wood. The technical problems that the steps of an existing production method are excessively simple, produced wood does not have the corrosion prevention performance, the water resistance performance and the deformation and cracking prevention performance, and the application range is small are solved. The production method of the five-prevention wood comprises the following steps that a, a coloring agent, a stabilizing agent, a dredging agent, a preservative and a weighting agent are poured into an ordinary blender to be mixed, mixed liquid is obtained, and the mixing time ranges from 10min to 20min; b, wood is placed into a closed pressure impregnation tank, the mixed liquid is added to the pressure impregnation tank until the pressure impregnation tank is completely filled with the liquid, the pressure is boosted to range from 1.2MPa to 1.5MPa, and kept for 2-3 hours, then the pressure is relieved, the mixed liquid is discharged, and the wood is taken out of the tank; c, drying treatment is conducted on the wood by the use of a drying system until the moisture content of the wood is reduced to range from 8% to 12%, and the drying temperature ranges from 48 DEG C to 52 DEG C; and d, the dried wood is placed into a heated liquid AB waterproof material to be soaked for 3-6 hours. The production method has the advantage of being wide in application range.