27 results about "Nerolidol" patented technology

The invention discloses a preparation method of a raspberry-derived exosome loaded with neroli essential oil. The preparation method comprises the following steps: preparing raspberry fruits into homogenate; centrifuging, collecting supernate, adjusting the pH value to 4.07.5, standing, and centrifuging again; taking supernate, adjusting the pH value to 7.2-7.4, adding polyethylene glycol, standing, centrifuging, collecting precipitate, and carrying out resuspension dispersion; performing microfiltration to obtain supernate, and combining electrophoresis dialysis and ultrafiltration concentration to obtain the high-purity raspberry exosome. And diluting the exosome, adding the diluted exosome into a dimethyl sulfoxide solution containing neroli essential oil, carrying out water bath stirring, carrying out ultrafiltration centrifugation, and taking a clear liquid to obtain the exosome loaded with the neroli essential oil. Efficient separation and purification of the raspberry exosome are achieved by applying an isoelectric precipitation technology, then the neroli essential oil is wrapped in the exosome, the stability of the essential oil is improved, the action time is prolonged, meanwhile, the neroli essential oil and active ingredients of the exosome generate a synergistic effect, and the antioxidant activity is jointly enhanced.

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention belongs to the technical field of mosquito larva prevention and control, and particularly relates to a mosquito-killing spreading oil agent and a preparation method and application thereof.The mosquito-killing spreading oil agent is composed of nerolidol, eugenol, methyl oleate, surfactants OP-4 and OP-10 and oleic acid, the mass percent of methyl oleate is 85%, the mass percent of a mixed preparation prepared from the surfactants OP-4 and OP-10 according to the mass ratio of 1: 1 is 5%, and the mass percent of oleic acid is 5%. The mosquito larva killing rate of the film spreading oil agent product within 60 minutes is 100%. Under the same condition, the effect of the insecticidal composition is better than that of pyrethrin, and the insecticidal speed is higher. The film spreading oil agent can reduce the chemical pesticide resistance of deet, and also can achieve the effects of environmental protection and efficient killing of mosquito larvae.

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

The invention belongs to the technical field of medicine detection, particularly provides a GC method for rapidly identifying rhizoma dryopteris crassirhizomae and fake rhizoma dryopteris crassirhizomae, and particularly discloses application of trans-nerolidol in identification or auxiliary identification of rhizoma dryopteris crassirhizomae and fake rhizoma dryopteris crassirhizomae. Compared with the prior art, the method provided by the invention has the advantages that the content in the male fern rhizome is lower, the content in other male fern rhizome fake products is lower, the male fern rhizome can be used as the marker, and a male fern rhizome identification method is established, has a better linear relation, has specificity and is good in instrument precision, stability, repeatability and reproducibility; the quantitation limit of the trans-nerolidol is 0.139 mu g / ml, and the detection limit is 0.046 mu g / ml; the trans-nerolidol content of 32 batches of cyrtomium rhizome samples is 0.11%-1.39%, the trans-nerolidol content of rhizoma dryopteris crassirhizomae should not be less than 0.25%, and a more accurate method is provided for identification and quality control of rhizoma dryopteris crassirhizomae.

The invention relates to the technical field of attractants and pest control, in particular to a volatile matter luring ball for luring hoverflies, which comprises a PVC (polyvinyl chloride) shell, a non-woven fabric liner and a slow-release attractant, the slow-release attractant is composed of a composite attractant, a paraffin oil solvent and a macroporous resin slow-release part in proportion. The compound attractant is prepared by mixing trans-beta-farnesene, nerolidol, 6-methyl-5-heptene-2-ketone and cis-3-hexene acetate according to a specific volume ratio, and the compound attractant can be used for attractant attractants. The preparation method comprises the following steps: oscillating and mixing the components with a solvent under a low-temperature condition, adsorbing on macroporous resin, and packaging. Through the synergistic effect of the multi-component volatile matters and the multi-stage slow-release structure, the luring ball realizes efficient, specific and lasting behavior luring on hoverflies, effectively prolongs the field lasting period, and improves the stability and practicability of natural enemy insect regulation and control.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The invention provides a depolymerization method of impurities in a floridin reaction liquid and a preparation method of floridin, and the specific steps are as follows: the floridin reaction liquid containing polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve to obtain a floridin depolymerization reaction liquid basically containing no polyisovaleraldehyde, and the floridin depolymerization reaction liquid containing no polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve. And separating the catalyst in the depolymerization reaction liquid, and carrying out optional refining to obtain a white flower alcohol product. The method disclosed by the invention has the advantages of mild conditions, no solvent, simple process, high depolymerization rate, no influence on the yield of the white flower alcohol, obvious improvement on the fragrance of the product and the like.

The invention belongs to but is not limited to the technical field of plant genetic engineering, and discloses a Nerolidol / Linalool synthetase gene MnTPS6 of machilus rubescens and an application of the Nerolidol / Linalool synthetase gene MnTPS6. The machilus nerolidol / Linalool synthetase gene MnTPS6 is a key gene for synthesis of the nerolidol / Linalool in plant genetic engineering, synthesis of the nerolidol / Linalool can be effectively regulated and controlled, expression protein of the machilus nerolidol / Linalool synthetase gene MnTPS6 is applied to synthesis and preparation of the nerolidol / Linalool, the yield is high, and the machilus nerolidol / Linalool synthetase gene MnTPS6 has important application value. Substrates of farnesyl pyrophosphate (FPP) and geranyl pyrophosphate (GPP) are added to the expression protein of the induced machilus nigrum Nerolidol / Linalool synthetase gene MnTPS6, the catalytic activity of the recombinant protein is detected, and a GC-MS (Gas Chromatography-Mass Spectrometer) detection component shows that the result shows that the MnTPS6 is a bifunctional enzyme for synthesizing Nerolidol / Linalool.

The invention relates to cigarette flavor with passion fruit flavor, adsorption particles and application of the cigarette flavor and the adsorption particles in cigarettes. The cigarette flavor is prepared from passion fruit peel essential oil, hexyl hexanoate, benzaldehyde, methyl farnesyl butyrate, geranyl acetone, nerolidol and beta-sweet bisabolol. Six specific spice components are combined to form a mixed spice, compared with single passion fruit peel essential oil serving as a spice, the components in the spice are matched with one another and have a synergistic effect, the passion fruit flavor can be provided during cigarette smoking, the fruit aroma characteristic of cigarettes is obviously improved, the aroma coordination is good, and the flavor of the cigarettes is greatly improved. The smoke characteristic of the cigarette can be improved; and after the spice is used for slow release treatment, the stability of the flavor of the passion fruit can be maintained, and the flavor of the spice cannot be changed due to the change of the original proportion of the components in the slow release process, so that the stability of sensory expression is realized, and the sensory quality of the tobacco product is comprehensively improved.

The invention discloses a tobacco terpenoid synthase gene NtTPS2184 and application thereof, and belongs to the technical field of plant molecular biology, the nucleotide sequence of the tobacco terpenoid synthase gene NtTPS2184 is shown as SEQ ID NO.1, the invention provides a recombinant expression vector, the recombinant expression vector is obtained by positively inserting the tobacco terpenoid synthase gene NtTPS2184 between BamHI and SacI sites of pGEX4.0 plasmid, and the recombinant expression vector is used for expressing the tobacco terpenoid synthase gene NtTPS2184. The invention also provides an application of the tobacco terpene synthase gene NtTPS2184 or the recombinant expression vector in the synthesis of linalool and trans-nerolidone by a catalytic substrate, and the terpene synthase gene NtTPS2184 provided by the invention can be massively expressed by using escherichia coli genetically engineered bacteria, so that the yield of the tobacco terpene synthase gene NtTPS2184 is increased, and the yield of the tobacco terpene synthase gene NtTPS2184 is increased. In the presence of a substrate geranyl pyrophosphate, the monoterpene synthase exerts the activity of the monoterpene synthase to catalytically synthesize linalool; and in the presence of a substrate farnesyl pyrophosphate, the activity of the sesquiterpene synthase is exerted, and the trans-nerolidinol is catalytically synthesized.

This invention belongs to the field of organic synthesis technology and relates to a method for preparing high-purity tertiary alcohols, comprising: (1) reacting the crude product of the compound shown in Formula I with p-nitrobenzoyl chloride; (2) recrystallizing the obtained product to obtain the compound shown in Formula II; and (3) hydrolyzing and distilling the compound shown in Formula II to obtain the pure product of the compound shown in Formula I, as shown below. The high-purity tertiary alcohol prepared by this method has a single impurity content of less than 0.1% and has been successfully applied to E-nerolidol, with a purity sufficient to meet the requirements for use as a pharmaceutical raw material. This method has high yield, low cost, and is suitable for industrial production.

The invention discloses a sweetening type composite floral compound additive and an application method thereof, and belongs to the technical field of food additives. The additive comprises erythritol, anhydrous citric acid, propylene glycol and a compound floral compound in a mass ratio of 5: 0.005: 0.01: (0.000175-0.004), wherein the compound floral compound is selected from at least three of alpha-ionone, beta-ionone, neryl acetate, nerol, nerolidol, terpinenol, farnerol and methyl dihydrojasmonate. By compounding three or more aroma substances and utilizing multiple aromas to synergistically influence taste perception, the effective sweetening effect can be realized on the premise of remarkably reducing the sugar consumption, and meanwhile, the taste comfort is improved. The method not only provides important reference for researching sweetening effects of different fragrances, has scientific research guidance value, but also provides a new strategy for realizing sugar reduction and gaining through aroma regulation and control for food industry, can respond to health requirements while maintaining flavor and taste, and has wide application prospect.

The application provides a Chinese trichopoda japonica attractant and a preparation method and application thereof, and belongs to the technical field of biological pest control. The active ingredient of the Chinese trichopoda japonica attractant is composed of volatile substances of potentilla chinensis, and the volatile substances include (Z)-3-hexen-1-ol 10-15 parts, gamma-terpinene 10-20 parts, trans-beta-myrcene 60-70 parts and nerolidol 0.5-1 part in volume fraction. The Chinese trichopoda japonica attractant as the effective component is combined with a diluent to further obtain an attractant preparation. The volatile substances in the potentilla chinensis are used to perform olfactory behavior response on the Chinese trichopoda japonica and are applied, the obtained attractant or attractant preparation has obvious attracting effect, is harmless to other natural enemies and is environment-friendly, and provides a new reference means for biological control.

This invention discloses an engineered Saccharomyces cerevisiae strain producing nerolidol, its preparation method, and its applications. By integrating the codon-optimized nerolidol synthase gene CaNES into the HO site of Saccharomyces cerevisiae Sc027, a genetically engineered strain producing nerolidol was obtained. The strain was then subjected to adaptive evolution culture and ARTP mutagenesis to obtain the nerolidol-producing engineered Saccharomyces cerevisiae strain. The engineered Saccharomyces cerevisiae strain of this invention can tolerate and effectively utilize the organic carbon source in tobacco extracts, significantly increasing the yield of nerolidol. Compared with the initial YCN001 strain, the YCN006 strain constructed in this invention showed a 13-fold increase in nerolidol yield. The aroma produced by the engineered Saccharomyces cerevisiae strain obtained in this invention through fermentation using tobacco extracts as a substrate combines the natural aroma of tobacco, fermentation aroma, and the floral aroma of nerolidol, enhancing the richness of the tobacco aroma.

The invention belongs to the technical field of mosquito control, and particularly relates to a preparation method and application of a plant-derived mosquito-preventing and insect-repelling hydrogel type solid mosquito repellent. Nerolidol, limonene and vanillin are mixed according to the volume ratio of 5: 5: 2 to serve as effective components, the hydrogel type solid mosquito repellent is prepared, and the defect that essential oil is short in mosquito repellent action time is overcome. The effective mosquito repelling time is longer than 25 days. Meanwhile, the slow-release mosquito repellent can achieve the effects of environmental protection and efficient mosquito repelling while reducing the chemical pesticide resistance of deet.

The invention provides a separated myzus persicae odorant binding protein and an application thereof, the protein can bind odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7-triene (DMNT), (E, E)-4, 8, 12-trimethyl-1, 3, 7, 11-tridecatetraene (TMTT), E-beta-farnesene, geraniol and geranyl acetone, and the protein has the advantages that the protein can bind the odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7, 11-tridecatetraene, (E, E)-4, 8, 12- The combination of the protein and the odorant can play an important role in biological control of insects.

A process for the production of lubricants for cosmetic use is described. According to the present invention, waste oils of biological origin are transesterified with terpene alcohols. From an economic point of view, these waste oils are advantageously chosen from used cooking oils (UCO) and / or reclaimed used cooking oils (RUCO). Preferably, said terpene alcohols are chosen from the group consisting of menthol, geraniol, citronellol, nerolidol, linalool.

The invention discloses nerolidol type acyl phloroglucinol meroterpenoid compounds as well as a preparation method and application thereof in pharmacy, relates to the technical field of biological medicines, and provides nerolidol type acyl phloroglucinol meroterpenoid compounds with eight structures and corresponding preparation methods. The compounds with the eight structures can have a good inhibition effect on triple negative breast cancer MDA-MB-231 cells. And the synthesis preparation method of the nerolidol type acyl phloroglucinol meroterpenoid compound is simple in process, simple to operate, low in production cost, green and environment-friendly, and can realize mass gram-level preparation.

The present invention relates to compositions for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles, the composition comprises delta-9-tetrahydrocannabinol (THC), alpha-bisabolol, guaiacol, and beta-caryophyllene and at least one selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma-terpinene, isoterpinene, alpha-terpinene, p-cymene, and at least one selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma-terpinene and additional terpenes of isopulegol and geraniol. The invention also relates to pharmaceutical formulations comprising such compositions for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles. The present invention also relates to methods of treating and / or preventing chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles. The invention also relates to kits comprising such compositions.

The application discloses a method for preparing farnesol from nerolidol, wherein a composite catalytic system composed of a phosphate and a vanadate or molybdate is used to perform isomerization reaction on nerolidol to prepare farnesol. The synthetic route of the application is simple, the catalytic system is simple and easy to obtain, the reaction process is simple, the isomerization reaction has very high chemical selectivity and stereoselectivity, and the synthesis method of farnesol is greatly simplified.

To provide a novel bean odor masking agent, a food composition containing the same, and a method for producing the same. [Solution] A bean odor masking agent comprising one or more compounds selected from the group consisting of lauric acid, α-terpinene, butyric acid, nerolidol, 2-pentanone, and sabinene hydrate.

The invention relates to a recombinant bacterium for producing trans-nerolidol as well as a construction method and application of the recombinant bacterium. The recombinant yeast is used for over-expressing an AcNES1 gene; the nucleotide sequence of the AcNES1 gene comprises a sequence as shown in SEQ ID NO. 1. According to the present invention, the yeast central metabolic network is systematically reconstructed, and the trans-nerolidol synthesis pathway is introduced, such that the trans-nerolidol is stably synthesized and accumulated by using the recombinant bacteria under the condition of using the ethanol as the main carbon source, and the trans-nerolidol yield can achieve 772 mg / L.

The invention relates to the field of daily chemical essence, in particular to a citrus aurantium flower essence base, a daily chemical product and perfume. The essence base is prepared from the following components in percentage by mass: a first note component and a second note component, a second note component; a third note and a fixed note component; a solvent; the sum of the mass percentages of the components is 100%. Wherein the first note component is prepared from trans-2-hexenal, limonene, leaf acetate, citronellal, alpha terpilenol and citral; the second note component is prepared from linalool, nerol, geraniol, neryl acetate, indole, methyl anthranilate and aryl jasmonone; the third note and fragrance fixing component comprises anisyl acetone, nerolidol, benzyl salicylate and benzyl benzoate. According to the citrus aurantium flower fragrance base, high simulation and hierarchical reproduction of natural citrus aurantium flower fragrance are achieved, meanwhile, excellent batch stability and fragrance persistence are achieved, and the cost is remarkably lower than that of a scheme depending on natural essential oil.

The invention discloses a Maotai-flavor liquor flower fragrance reference sample and a preparation method and application thereof, and belongs to the technical field of liquor flavor analysis and quality control. Ten key flower fragrance active compounds such as linalool, trans-nerolidol and phenethyl alcohol are screened out through aroma recombination and deletion experiments, and a narrow flower fragrance reference sample with an ethanol water solution as a solvent is constructed; six non-flower fragrance modification components such as ethyl propionate and n-hexanal derived from natural flowers are further introduced to form a generalized flower fragrance reference sample. The method effectively solves the problem that the evaluation of the fragrance of the Maotai-flavor liquor depends on subjective description for a long time and is lack of a quantitative reference, provides a scientific basis and a practical tool for flavor evaluation, quality control and sensory training of the liquor, and can be used as a core fragrance base to be extensively applied to the field of daily chemical products.

The invention discloses a (E)-nerolidol synthetase mutant and application of the (E)-nerolidol synthetase mutant in production of (E)-nerolidol, and belongs to the technical field of biological engineering. According to the invention, isoleucine at the 323rd site of (E)-nerolidol synthetase is mutated into valine, serine at the 428th site of (E)-nerolidol synthetase is mutated into threonine, and an engineering strain LN47 is constructed through overexpression in serratia marcescens (HBQA7). Under the condition of shake flask fermentation, the yield of (E)-nerolidol of the engineering strain LN47 reaches 5.11 g / L; the yield is obviously increased to 70.5 g / L through amplification culture in a 5 L fermentation tank. The invention provides an efficient, economic and environment-friendly new method for industrial biosynthesis of (E)-nerolidol.

This invention discloses a method for preparing liquid fermented tea that enhances the floral and fruity aroma of tea leaves, belonging to the field of fermented tea technology. This invention uses Pichia pastoris (a type of yeast). Pichia cactophila FL2 fermented tea liquor, after fermentation, shows an increase of more than 11.59 times in the content of floral and fruity aroma compounds such as terpinene, an increase of 86.58 times in the content of phenylethanol, an increase of 82.83 times in the content of phenethyl acetate, and an increase of 369.26 μg / mL in the content of 1-butanol and o-cymene from 0. In addition, the increases in cymene, α-terpineol, and nerolidol reached 5.41, 13.54, and 3.34 times, respectively. The interaction of various aroma components gives the tea liquor a unique "lemon and citrus fruity aroma" flavor, while also containing sweet and sour aroma compounds. It has a good flavor and is of industrial promotion value.