39 results about "Nerolidol" patented technology

The invention discloses a preparation method of a raspberry-derived exosome loaded with neroli essential oil. The preparation method comprises the following steps: preparing raspberry fruits into homogenate; centrifuging, collecting supernate, adjusting the pH value to 4.07.5, standing, and centrifuging again; taking supernate, adjusting the pH value to 7.2-7.4, adding polyethylene glycol, standing, centrifuging, collecting precipitate, and carrying out resuspension dispersion; performing microfiltration to obtain supernate, and combining electrophoresis dialysis and ultrafiltration concentration to obtain the high-purity raspberry exosome. And diluting the exosome, adding the diluted exosome into a dimethyl sulfoxide solution containing neroli essential oil, carrying out water bath stirring, carrying out ultrafiltration centrifugation, and taking a clear liquid to obtain the exosome loaded with the neroli essential oil. Efficient separation and purification of the raspberry exosome are achieved by applying an isoelectric precipitation technology, then the neroli essential oil is wrapped in the exosome, the stability of the essential oil is improved, the action time is prolonged, meanwhile, the neroli essential oil and active ingredients of the exosome generate a synergistic effect, and the antioxidant activity is jointly enhanced.

Provided are a nerolidol synthetase comprising structural domains having Pfam numbers PF01397 and PF03936, and a use thereof. The amino acid sequence of the nerolidol synthase is as shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 11, or SEQ ID NO: 12, and a nucleotide sequence encoding a nucleic acid molecule is as shown in SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, or SEQ ID NO: 10. The use includes: integrating a coding gene of the nerolidol synthetase into a nucleic acid construct and introducing same into a host cell to obtain a recombinant bacterium, so that the coding gene is expressed in the recombinant bacterium. Thus, biosynthesis of nerolidol is implemented, and the yield of nerolidol is remarkably improved.

An antifungal composition including a first essential oil, and a second essential oil, where the composition is configured to reduce disease onset, pathogen spread, or a combination thereof. Further, an antifungal compound including one or more aroma compounds selected from 4-(4-hydroxyphenyl)-2-butanone, furaneol, ethyl methylphenylglycidate, ethyl hexanoate, ethyl butanoate, beta-ionone, alpha-ionone, (R)-(+)-limonene, (S)-(-)-limonene, cis-3-Hexen-1-ol, nerol, linalool, 2-heptanone, alpha-terpineol, beta-damascenone, β-caryophyllene, ethyl 2-methylbutanoate, β-myrcene, gamma-octalactone, alpha-humulene, nerolidol, (E,E)-2,4-decadienal, (E,E)-α-farnesene, vanillin, phenylethyl acetate, citral, 3-methylbutan-1-ol, or a combination thereof.

The invention relates to the technical field of green prevention and control of agricultural pests, in particular to a nerolidol-based female bactrocera cucurbitae attractant and application thereof. The female bactrocera cucurbitae attractant takes nerolidol as a single active ingredient, the effective concentration is 0.01 mg / mL, and a solvent is selected from distilled water, dimethyl sulfoxide (DMSO) or corn oil. Experiments show that the attractant has a high attraction rate on female adult bactrocera cucurbitae under the concentration, and keeps stable activity in a high-temperature environment of 26-35 DEG C. When the attractant is applied, a trapping carrier is coated with the attractant and placed in a field trapping device. The specific taxis of female bactrocera cucurbitae to nerolidol which is a plant rot characteristic volatile matter is utilized for the first time, the limitation of chemical pesticide resistance is broken through, and the method has environmental friendliness and high-temperature adaptability and can be widely applied to pest monitoring and green prevention and control in melon fruit and vegetable planting areas.

The invention discloses lactobacillus casei capable of improving the flavor of a tea beverage through fermentation and application of the lactobacillus casei. The lactobacillus casei is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number of the lactobacillus casei is CGMCC No.32672, and the preservation date of the lactobacillus casei is November 18, 2024. The lactobacillus casei can be used for producing extracellular beta-glucosidase, polyphenol oxidase and peroxidase; when being used for fermentation, the fermentation broth can improve the flavor and color of a tea beverage, increase the content of organic acid, reduce the bitter taste of the tea beverage, generate new volatile aroma substances such as nerolidol, isobutanol, ethyl hexanoate, ethyl 3-hexenoate, ethyl caprylate, ethyl 2-hexenoate and the like, and enrich the aroma substance composition of the tea beverage. The invention provides a novel tea beverage production process which has the advantages of simplicity and convenience in operation, low cost, remarkable effect and the like, and is suitable for industrial production.

The invention belongs to the technical field of mosquito larva prevention and control, and particularly relates to a mosquito-killing spreading oil agent and a preparation method and application thereof.The mosquito-killing spreading oil agent is composed of nerolidol, eugenol, methyl oleate, surfactants OP-4 and OP-10 and oleic acid, the mass percent of methyl oleate is 85%, the mass percent of a mixed preparation prepared from the surfactants OP-4 and OP-10 according to the mass ratio of 1: 1 is 5%, and the mass percent of oleic acid is 5%. The mosquito larva killing rate of the film spreading oil agent product within 60 minutes is 100%. Under the same condition, the effect of the insecticidal composition is better than that of pyrethrin, and the insecticidal speed is higher. The film spreading oil agent can reduce the chemical pesticide resistance of deet, and also can achieve the effects of environmental protection and efficient killing of mosquito larvae.

The invention discloses a traditional Chinese medicine combination effective part capable of improving diabetic peripheral neuropathy. The traditional Chinese medicine combination effective part is prepared from a volatile oil effective part, a water-soluble effective part and an alcohol-soluble effective part, the effective part of the volatile oil comprises alpha-ocimene, alpha-santalene, bisabolol, beta-bisabolol and nerolidol; the water-soluble effective part comprises salvianolic acid A, salvianolic acid B and tanshinol; the alcohol-soluble effective part is prepared from Z-ligustilide, alpha-masticinic acid, beta-masticinic acid, tanshinone IIA, and 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone, and the alcohol-soluble effective part is prepared from the following raw materials in parts by weight: 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone. The traditional Chinese medicine composition effective part provided by the invention can regulate blood sugar, improve the conduction speed of sciatic nerves, repair damaged tissues, inhibit oxidative stress reaction, resist inflammation and relieve pain, so that the diabetic peripheral neuropathy is improved, the curative effect is reliable, the safety is good, the adverse reaction is low, and the traditional Chinese medicine composition effective part can be used for preparing a medicinal preparation for improving the diabetic peripheral neuropathy.

The application belongs to the technical field of biological medicine, and particularly relates to a lactobacillus paracasei and application thereof. The lactobacillus paracasei ZY101 is preserved in the China General Microbiological Culture Collection Center, has a preservation number of CGMCC No. 32360, a preservation date of October 25, 2024, and an address of No. 3, Beichen West Road, Chaoyang District, Beijing. Compared with a commercial bacillus acidophilus, the apricot vinegar prepared by using the lactobacillus paracasei ZY101 has new substances including linalool, alpha-farnesene, 2-phenylacetic acid ethyl ester and geranylgeraniol, and further promotes the aroma of the apricot vinegar. Compared with the commercial bacillus acidophilus, the existing substances are obviously improved, and specifically include ethyl acetate, isoamyl acetate, ethyl octanoate, ethyl hexanoate, acetoin, methyl palmitate, gamma-deca-lactone, ethyl dodecanoate, delta-deca-lactone, trans-nerolidol and dihydro-beta-ionone.

The invention belongs to the technical field of medicine detection, particularly provides a GC method for rapidly identifying rhizoma dryopteris crassirhizomae and fake rhizoma dryopteris crassirhizomae, and particularly discloses application of trans-nerolidol in identification or auxiliary identification of rhizoma dryopteris crassirhizomae and fake rhizoma dryopteris crassirhizomae. Compared with the prior art, the method provided by the invention has the advantages that the content in the male fern rhizome is lower, the content in other male fern rhizome fake products is lower, the male fern rhizome can be used as the marker, and a male fern rhizome identification method is established, has a better linear relation, has specificity and is good in instrument precision, stability, repeatability and reproducibility; the quantitation limit of the trans-nerolidol is 0.139 mu g / ml, and the detection limit is 0.046 mu g / ml; the trans-nerolidol content of 32 batches of cyrtomium rhizome samples is 0.11%-1.39%, the trans-nerolidol content of rhizoma dryopteris crassirhizomae should not be less than 0.25%, and a more accurate method is provided for identification and quality control of rhizoma dryopteris crassirhizomae.

Provided are compositions comprising terpene mixtures consisting of 1000-4500 ppm myrcene, 1000-4000 ppm terpineol, 1000-5500 ppm caryophyllene and 1000-45000 ppm nerolidol; 1000-4500 ppm alpha-pinene, 1000-4000 ppm sabinene, 1000-4000 ppm limonene, 500-4000 ppm borneol and 1000-4500 ppm caryophyllene; 1000-4500 ppm alpha-pinene, 1000-4000 ppm linalool, 1000-4000 ppm terpineol, 1000-4000 ppm borneol, 1000-4500 ppm caryophyllene and 1000-4000 ppm nerolidol; 1000-4000 ppm myrcene, 500-5000 ppm linalool, 1000-4500 ppm caryophyllene and 500-4500 ppm nerolidol; or 1000-5500 ppm alpha-pinene, 1000-4000 ppm limonene, 500-4000 ppm linalool and 1000-4500 ppm caryophyllene, and uses in therapy.

The invention relates to the technical field of attractants and pest control, in particular to a volatile matter luring ball for luring hoverflies, which comprises a PVC (polyvinyl chloride) shell, a non-woven fabric liner and a slow-release attractant, the slow-release attractant is composed of a composite attractant, a paraffin oil solvent and a macroporous resin slow-release part in proportion. The compound attractant is prepared by mixing trans-beta-farnesene, nerolidol, 6-methyl-5-heptene-2-ketone and cis-3-hexene acetate according to a specific volume ratio, and the compound attractant can be used for attractant attractants. The preparation method comprises the following steps: oscillating and mixing the components with a solvent under a low-temperature condition, adsorbing on macroporous resin, and packaging. Through the synergistic effect of the multi-component volatile matters and the multi-stage slow-release structure, the luring ball realizes efficient, specific and lasting behavior luring on hoverflies, effectively prolongs the field lasting period, and improves the stability and practicability of natural enemy insect regulation and control.

The invention discloses oolong wheat tea and a preparation method thereof, and belongs to the technical field of wheat tea processing. According to the technical scheme, the oolong wheat tea is prepared by blending barley extract liquor and oolong tea extract liquor. The barley fragrance index of the barley extract is greater than 0.1 and less than 0.9; the wheat aroma index is calculated according to the following formula: wheat aroma index = (2-acetylpyrrole + 2-ethylpyrazine + dimethylpyrazine + methylpyrazine) / (5-methylfurfural + 2-acetylfuran + furfural); the tea aroma index of the tea leaves for preparing the oolong tea extract liquor is greater than 2.5; the tea aroma index is calculated according to the following formula: tea aroma index = A / B; the total flower fragrance A is linalool, geraniol, cis-jasmonone, jasmonlactone, nerolidol, methyl jasmonate and indole; the total odor amount B is equal to the sum of cis-2, 4-heptadienal, trans-2, 4-heptadienal and indole. The method is applied to processing of oolong wheat tea, and the problems that the oolong wheat tea is not harmonious in fragrance, poor in palatability and prone to precipitation are solved.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of teprenone. The invention aims to solve the technical problems that the existing teprenone synthesis route is complicated, the stereo configuration of a synthesis precursor is difficult to control and the like. According to the method, alpha-farnesene, beta-farnesene, farnesol and nerolidol which are sourced from microbial fermentation are used for preparing a farnesyl acetone crude product, and then high-purity all-trans (5E, 9E)-farnesyl acetone is obtained through rectification, or all-trans (5E, 9E)-farnesyl acetone is directly synthesized from beta-farnesene and farnesol. Therefore, commercial teprenone with qualified quality can be obtained through subsequent reaction.

The present invention discloses an attractant composition for adult citrus psyllids and its use. The composition comprises the following components by weight: 0.1-1.1 parts of α-phellandrene, 0.1-0.8 parts of 1-butyl-2-isobutyl phthalate, 4.6-5.6 parts of trans-nerolidol, and 3.5-4.5 parts of β-caryophyllene. The synergist provided by the present invention is inexpensive, can reduce the cost of producing the attractant core, and is suitable for widespread promotion.

The present invention relates to a composition comprising delta-9-tetrahydrocannabinol (THC), alpha-bisabolol, guaiol, beta-caryophyllene and at least one terpene selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma-terpinene, terpinolene, alpha-terpinene, para-cymene, isopulegol and geraniol. The invention also relates to a pharmaceutical formulation comprising such composition. The pharmaceutical formulation according to the present invention may be used in medicine, specifically in the treatment and / or prevention of diseases associated with pain such as chronic cancer pain, somatic pain, visceral pain, central neuropathic pain, peripheral neuropathic pain or complex pain syndromes.

The invention provides a depolymerization method of impurities in a floridin reaction liquid and a preparation method of floridin, and the specific steps are as follows: the floridin reaction liquid containing polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve to obtain a floridin depolymerization reaction liquid basically containing no polyisovaleraldehyde, and the floridin depolymerization reaction liquid containing no polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve. And separating the catalyst in the depolymerization reaction liquid, and carrying out optional refining to obtain a white flower alcohol product. The method disclosed by the invention has the advantages of mild conditions, no solvent, simple process, high depolymerization rate, no influence on the yield of the white flower alcohol, obvious improvement on the fragrance of the product and the like.

The invention belongs to but is not limited to the technical field of plant genetic engineering, and discloses a Nerolidol / Linalool synthetase gene MnTPS6 of machilus rubescens and an application of the Nerolidol / Linalool synthetase gene MnTPS6. The machilus nerolidol / Linalool synthetase gene MnTPS6 is a key gene for synthesis of the nerolidol / Linalool in plant genetic engineering, synthesis of the nerolidol / Linalool can be effectively regulated and controlled, expression protein of the machilus nerolidol / Linalool synthetase gene MnTPS6 is applied to synthesis and preparation of the nerolidol / Linalool, the yield is high, and the machilus nerolidol / Linalool synthetase gene MnTPS6 has important application value. Substrates of farnesyl pyrophosphate (FPP) and geranyl pyrophosphate (GPP) are added to the expression protein of the induced machilus nigrum Nerolidol / Linalool synthetase gene MnTPS6, the catalytic activity of the recombinant protein is detected, and a GC-MS (Gas Chromatography-Mass Spectrometer) detection component shows that the result shows that the MnTPS6 is a bifunctional enzyme for synthesizing Nerolidol / Linalool.

The invention relates to cigarette flavor with passion fruit flavor, adsorption particles and application of the cigarette flavor and the adsorption particles in cigarettes. The cigarette flavor is prepared from passion fruit peel essential oil, hexyl hexanoate, benzaldehyde, methyl farnesyl butyrate, geranyl acetone, nerolidol and beta-sweet bisabolol. Six specific spice components are combined to form a mixed spice, compared with single passion fruit peel essential oil serving as a spice, the components in the spice are matched with one another and have a synergistic effect, the passion fruit flavor can be provided during cigarette smoking, the fruit aroma characteristic of cigarettes is obviously improved, the aroma coordination is good, and the flavor of the cigarettes is greatly improved. The smoke characteristic of the cigarette can be improved; and after the spice is used for slow release treatment, the stability of the flavor of the passion fruit can be maintained, and the flavor of the spice cannot be changed due to the change of the original proportion of the components in the slow release process, so that the stability of sensory expression is realized, and the sensory quality of the tobacco product is comprehensively improved.

The invention discloses a tobacco terpenoid synthase gene NtTPS2184 and application thereof, and belongs to the technical field of plant molecular biology, the nucleotide sequence of the tobacco terpenoid synthase gene NtTPS2184 is shown as SEQ ID NO.1, the invention provides a recombinant expression vector, the recombinant expression vector is obtained by positively inserting the tobacco terpenoid synthase gene NtTPS2184 between BamHI and SacI sites of pGEX4.0 plasmid, and the recombinant expression vector is used for expressing the tobacco terpenoid synthase gene NtTPS2184. The invention also provides an application of the tobacco terpene synthase gene NtTPS2184 or the recombinant expression vector in the synthesis of linalool and trans-nerolidone by a catalytic substrate, and the terpene synthase gene NtTPS2184 provided by the invention can be massively expressed by using escherichia coli genetically engineered bacteria, so that the yield of the tobacco terpene synthase gene NtTPS2184 is increased, and the yield of the tobacco terpene synthase gene NtTPS2184 is increased. In the presence of a substrate geranyl pyrophosphate, the monoterpene synthase exerts the activity of the monoterpene synthase to catalytically synthesize linalool; and in the presence of a substrate farnesyl pyrophosphate, the activity of the sesquiterpene synthase is exerted, and the trans-nerolidinol is catalytically synthesized.

This invention belongs to the field of organic synthesis technology and relates to a method for preparing high-purity tertiary alcohols, comprising: (1) reacting the crude product of the compound shown in Formula I with p-nitrobenzoyl chloride; (2) recrystallizing the obtained product to obtain the compound shown in Formula II; and (3) hydrolyzing and distilling the compound shown in Formula II to obtain the pure product of the compound shown in Formula I, as shown below. The high-purity tertiary alcohol prepared by this method has a single impurity content of less than 0.1% and has been successfully applied to E-nerolidol, with a purity sufficient to meet the requirements for use as a pharmaceutical raw material. This method has high yield, low cost, and is suitable for industrial production.

The invention discloses a sweetening type composite floral compound additive and an application method thereof, and belongs to the technical field of food additives. The additive comprises erythritol, anhydrous citric acid, propylene glycol and a compound floral compound in a mass ratio of 5: 0.005: 0.01: (0.000175-0.004), wherein the compound floral compound is selected from at least three of alpha-ionone, beta-ionone, neryl acetate, nerol, nerolidol, terpinenol, farnerol and methyl dihydrojasmonate. By compounding three or more aroma substances and utilizing multiple aromas to synergistically influence taste perception, the effective sweetening effect can be realized on the premise of remarkably reducing the sugar consumption, and meanwhile, the taste comfort is improved. The method not only provides important reference for researching sweetening effects of different fragrances, has scientific research guidance value, but also provides a new strategy for realizing sugar reduction and gaining through aroma regulation and control for food industry, can respond to health requirements while maintaining flavor and taste, and has wide application prospect.

The application provides a Chinese trichopoda japonica attractant and a preparation method and application thereof, and belongs to the technical field of biological pest control. The active ingredient of the Chinese trichopoda japonica attractant is composed of volatile substances of potentilla chinensis, and the volatile substances include (Z)-3-hexen-1-ol 10-15 parts, gamma-terpinene 10-20 parts, trans-beta-myrcene 60-70 parts and nerolidol 0.5-1 part in volume fraction. The Chinese trichopoda japonica attractant as the effective component is combined with a diluent to further obtain an attractant preparation. The volatile substances in the potentilla chinensis are used to perform olfactory behavior response on the Chinese trichopoda japonica and are applied, the obtained attractant or attractant preparation has obvious attracting effect, is harmless to other natural enemies and is environment-friendly, and provides a new reference means for biological control.

This invention discloses an engineered Saccharomyces cerevisiae strain producing nerolidol, its preparation method, and its applications. By integrating the codon-optimized nerolidol synthase gene CaNES into the HO site of Saccharomyces cerevisiae Sc027, a genetically engineered strain producing nerolidol was obtained. The strain was then subjected to adaptive evolution culture and ARTP mutagenesis to obtain the nerolidol-producing engineered Saccharomyces cerevisiae strain. The engineered Saccharomyces cerevisiae strain of this invention can tolerate and effectively utilize the organic carbon source in tobacco extracts, significantly increasing the yield of nerolidol. Compared with the initial YCN001 strain, the YCN006 strain constructed in this invention showed a 13-fold increase in nerolidol yield. The aroma produced by the engineered Saccharomyces cerevisiae strain obtained in this invention through fermentation using tobacco extracts as a substrate combines the natural aroma of tobacco, fermentation aroma, and the floral aroma of nerolidol, enhancing the richness of the tobacco aroma.

The invention belongs to the technical field of mosquito control, and particularly relates to a preparation method and application of a plant-derived mosquito-preventing and insect-repelling hydrogel type solid mosquito repellent. Nerolidol, limonene and vanillin are mixed according to the volume ratio of 5: 5: 2 to serve as effective components, the hydrogel type solid mosquito repellent is prepared, and the defect that essential oil is short in mosquito repellent action time is overcome. The effective mosquito repelling time is longer than 25 days. Meanwhile, the slow-release mosquito repellent can achieve the effects of environmental protection and efficient mosquito repelling while reducing the chemical pesticide resistance of deet.

The invention provides a separated myzus persicae odorant binding protein and an application thereof, the protein can bind odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7-triene (DMNT), (E, E)-4, 8, 12-trimethyl-1, 3, 7, 11-tridecatetraene (TMTT), E-beta-farnesene, geraniol and geranyl acetone, and the protein has the advantages that the protein can bind the odorant substances including nerolidol, myrcene, ocimene, bisabolol, beta-ionone, (E)-4, 8-dimethylnonyl-1, 3, 7, 11-tridecatetraene, (E, E)-4, 8, 12- The combination of the protein and the odorant can play an important role in biological control of insects.

A process for the production of lubricants for cosmetic use is described. According to the present invention, waste oils of biological origin are transesterified with terpene alcohols. From an economic point of view, these waste oils are advantageously chosen from used cooking oils (UCO) and / or reclaimed used cooking oils (RUCO). Preferably, said terpene alcohols are chosen from the group consisting of menthol, geraniol, citronellol, nerolidol, linalool.

The invention discloses nerolidol type acyl phloroglucinol meroterpenoid compounds as well as a preparation method and application thereof in pharmacy, relates to the technical field of biological medicines, and provides nerolidol type acyl phloroglucinol meroterpenoid compounds with eight structures and corresponding preparation methods. The compounds with the eight structures can have a good inhibition effect on triple negative breast cancer MDA-MB-231 cells. And the synthesis preparation method of the nerolidol type acyl phloroglucinol meroterpenoid compound is simple in process, simple to operate, low in production cost, green and environment-friendly, and can realize mass gram-level preparation.

The present invention relates to compositions for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles, the composition comprises delta-9-tetrahydrocannabinol (THC), alpha-bisabolol, guaiacol, and beta-caryophyllene and at least one selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma-terpinene, isoterpinene, alpha-terpinene, p-cymene, and at least one selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma-terpinene and additional terpenes of isopulegol and geraniol. The invention also relates to pharmaceutical formulations comprising such compositions for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles. The present invention also relates to methods of treating and / or preventing chronic musculoskeletal pain, including chronic lumbodorsal pain (CLBP), chronic non-specific lumbodorsal pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain affecting body parts or systems, such as joints, tendons, ligaments, bones and / or muscles. The invention also relates to kits comprising such compositions.

The application discloses a method for preparing farnesol from nerolidol, wherein a composite catalytic system composed of a phosphate and a vanadate or molybdate is used to perform isomerization reaction on nerolidol to prepare farnesol. The synthetic route of the application is simple, the catalytic system is simple and easy to obtain, the reaction process is simple, the isomerization reaction has very high chemical selectivity and stereoselectivity, and the synthesis method of farnesol is greatly simplified.

To provide a novel bean odor masking agent, a food composition containing the same, and a method for producing the same. [Solution] A bean odor masking agent comprising one or more compounds selected from the group consisting of lauric acid, α-terpinene, butyric acid, nerolidol, 2-pentanone, and sabinene hydrate.