1210 results about "Ketene" patented technology

Size press compositions and methods for producing sized paper products, including liner board, are disclosed. The size press compositions contain at least one non-reactive cationic surface sizing agent, at least one reactive sizing agent, at least one promoter resin, at least one binder, and water. The at least one non-reactive cationic surface sizing agent may be a polymer in the form of a dispersion, an emulsion or a latex with a positive zeta potential below about pH 6. The at least one reactive sizing agent may be a dispersion, an emulsion or a latex including an alkyl ketene dimer or an alkyl succinic anhydride. The at least one promoter resin may be a polyaminoamide-epichlorohydrin resin or poly (dimethyldiallylammonium chloride).

The present invention relates to a new industrial process for the synthesis of solvate- free 17a-acetoxy-11ss-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB -2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process. The process according to the invention is the following: i) 3-(ethylene-dioxy)-estra-5(10),9(11)-diene-17-one of formula (X) is reacted with potassium acetilyde formed in situ in dry tetrahydrofuran by known method, ii) the obtained 3-(ethylene-dioxy)-17a-ethynyl-17ss-hydroxy-estra-5(10),9(11)-diene of formula (IX) is reacted with phenylsulfenyl chloride in dichloromethane in the presence of triethylamine and acetic acid, iii) the obtained isomeric mixture of 3-(ethylene-dioxy)-21-(phenyl-sulfinyl)-19-norpregna-5(10),9(11),17(20),20-tetraene of formula (VIII) is reacted first with sodium methoxide in methanol, then with trimethyl phosphite, iv) the obtained 3-(ethylene-dioxy)-17a-hydroxy-20-methoxy-19-norpregna-5(10),9(11),20-triene of formula (VII) is reacted with hydrogen chloride in methanol, then v) the obtained 3-(ethylene-dioxy)-17a-hydroxy-19-norpregna-5(10),9(11l); -diene-20- one of formula (VI) is reacted with ethylene glycol hi dichloromethane in the presence of trimethyl orthoformate and p-toluenesulfonic acid by known method, vi) the obtained 3,3,20,20-bis(ethylene-dioxy)-17a-hydroxy-19-norpregna- 5(10),9(11)-diene of formula (V) is reacted with hydrogen peroxide in a mixture of pyridine and dichloromethane in the presence of hexachloroacetone by known method, vii) the obtained 3,3,20,20-bis(ethylene-dioxy)-17a-hydroxy-5,10-epoxy-19-norpregn-9(11)-ene of formula (IV), containing approximately a 1:1 mixture of 5a,10a- and 5ss,10ss-epoxides, is isolated from the solution and reacted with a Grignard reagent obtained from 4-bromo-N,N-dimethyl-aniline in tetrahydrofuran.

A non-naturally occurring microbial organism has cyclohexanone pathways that include at least one exogenous nucleic acid encoding a cyclohexanone pathway enzyme. A pathway includes a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on C—C bond), a 2-ketocyclohexane-1-carboxylate decarboxylase and an enzyme selected from a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxyl-CoA transferase, and a 2-ketocyclohexane-1-carboxyl-CoA synthetase. A pathway includes an enzyme selected from a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on C—C bond), a 6-ketocyclohex-1-ene-1-carboxyl-CoA synthetase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on thioester), a 6-ketocyclohex-1-ene-1-carboxyl-CoA transferase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA reductase, a 6-ketocyclohex-1-ene-1-carboxylate decarboxylase, a 6-ketocyclohex-1-ene-1-carboxylate reductase, a 2-ketocyclohexane-1-carboxyl-CoA synthetase, a 2-ketocyclohexane-1-carboxyl-CoA transferase, a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxylate decarboxylase, and a cyclohexanone dehydrogenase. A pathway includes an adipate semialdehyde dehydratase, a cyclohexane-1,2-diol dehydrogenase, and a cyclohexane-1,2-diol dehydratase. A pathway includes a 3-oxopimelate decarboxylase, a 4-acetylbutyrate dehydratase, a 3-hydroxycyclohexanone dehydrogenase, a 2-cyclohexenone hydratase, a cyclohexanone dehydrogenase and an enzyme selected from a 3-oxopimeloyl-CoA synthetase, a 3-oxopimeloyl-CoA hydrolase (acting on thioester), and a 3-oxopimeloyl-coA transferase. Each these pathways can include a PEP carboxykinase. A method for producing cyclohexanone includes culturing these non-naturally occurring microbial organisms.

A method for reducing the concentration of cyclohexenone in a cyclohexenone containing organic mixture is disclosed. The method includes contacting an organic mixture comprising cyclohexenone with an effective amount of at least one of sulfurous acid, a salt of sulfurous acid, an alkali hydroxide, or a mixture of two or more of these compounds.

The invention relates to a modified AKD (Alkyl Ketene Dimer) neutral sizing agent which is a milk white liquid in appearance. The modified AKD neutral sizing agent comprises the following main materials: AKD, starch, paraffin, high molecular dispersant and other assistant materials. The modified AKD neutral sizing agent is mainly used for sizing paper pulp and improving the water resistance and impermeability of paper in the paper-making production process, and the consumption for every ton of paper is 10-20kg. Compared with like products, the quickly-cured modified AKD neutral sizing agent has the following advantages: (1) effective ingredient particles of the product are finer and more uniform and can be cured more tightly, the product has a longer quality guarantee period, and convenience is provided for transportation and storage; (2) the product is applicable to neutral paper pulp and can no longer result in the production of acidic paper-making sewage, thereby being beneficial to environmental protection; (3) the use effect of the product can act quickly, and the curing time is extremely short, thereby facilitating the effect monitoring and quality control in use, improving the production efficiency and enhancing the yield of paper; and (4) the consumption of the product is lower than that of other like products, thereby reducing the cost of production materials and improving the economic benefits of customers.

The invention discloses a food wrapping paper and a production method thereof. Poplar chemical mechanical pulp, bleached kraft softwood pulp and bleached kraft hardwood pulp are used as fiber raw materials. Sizing, desanding and degassing, sizing, fine sieving, wire dehydration forming, pressing, pre-drying, surface sizing, post-drying, calendering, coiling, and packaging to form food packaging paper. The present invention uses the surface sizing treatment method to process the product, and adds a starch surface sizing agent to the surface sizing to improve water resistance and adds a small amount of sizing agent alkyl ketene dimer to the surface sizing glue, which can Improve the retention rate, save costs, and make products more cost-effective.

The invention relates to a method for extracting ketene dimer by rectifying residues and pumped liquid. The method comprises the following steps that firstly, hydrolysis is carried out, wherein primary residues and the pumped liquid are mixed in the proportion of 2:1 and heated to 65-75 DEG C through a membrane type evaporator, ketene dimer is evaporated out, crude ketene dimer obtained through cooling of a primary condenser and a secondary condenser enters a high-order storage tank and is mixed with crude ketene dimer generated in a polymerization section, and then mixed crude ketene dimer enters a rectifying section; secondly, secondary residues formed in the membrane type evaporator and acetic anhydride in the condensers enter a hydrolysis section for hydrolysis, and acetone, dilute acetic acid and solid waste residues are obtained; thirdly, tail gas at the hydrolysis section is fed to a water scrubber to be absorbed. The method has the advantages that crude ketene dimer is recycled through heating of the membrane evaporator, the yield of crude ketene dimer is increased inside the system, consumption of glacial acetic acid is reduced, waste gas and residues generated in the production process are digested and absorbed, solid waste is greatly reduced, and zero waste water emission is achieved.

The invention relates to a delivery device for the controlled release of the therapeutically active agent gestodene, over a prolonged period of time, at a release rate of 0,1-300 mug / day, said device comprising a core comprising at least said therapeutically active agent, and a membrane encasing said core wherein said membrane is made of an elastomer. According to the invention, the elastomer is a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms of the siloxane units, and the release rate of said therapeutically active agent of said delivery device is regulated by the amount of said 3,3,3-trifluoropropyl groups.

The invention relates to a process for preparing sorbic acid by cleaving the sorbic acid polyester prepared from crotonaldehyde and ketene, the sorbic acid polyester being distilled and the cleavage being catalyzed by an amine, which comprises separating off the amine from the distillation residue by distillation under reduced pressure and at a temperature which is higher than the temperature of the polyester distillation and recovering it.

A filter medium for an air filter, characterized in that it comprises a filter material having a glass fiber as its primary component and an alkyl ketene dimer adhered to the surface of the glass fiber; and a method for producing the filter medium which comprises a step of subjecting a dispersed slurry of a raw material fiber to a wet papermaking to form a wet paper, a step of immersing the wet paper in an aqueous dispersion or solution of the dimer or a liquid mixture of the dimer and a binder resin, or applying or spraying any of the above-mentioned liquids to the wet paper, to thereby allow the dimer to adhere onto the surface of the glass fiber, and a step of drying the resultant wet paper having the dimer adhered thereto. The filter medium exhibits a reduced amount of an out gas generated when it is used with ventilation and also exhibits high water-repellency and satisfactory strength in various applications such as air conditioning of a building and semiconductor manufacturing.

The invention provides a bromide type muscle relaxant, which mainly comprises a method for synthesizing rocuronium bromide, vecuronium bromide, pancuronium bromide and pipecuronium bromide , and is mainly characterized by adopting a ketene as an acylating agent during the process of transforming 5Alpha-androstane -2-alkene-17-alkone to 17-acetoxyl group-5Alpha- androstane-2, and 16-diene, adopting a stress kettle as a reactor when realizing the step of ring-opening and condensation of the 2 Alpha and 3 Alpha-epoxy compound, and adding a solid catalyst and a desiccant in the last step of operation of rocuronium bromide to greatly improve the reaction yield and the quality of products. The technology provided by the invention can shorten the synthesis time of the bromide type muscle relaxant, simplify the operation steps, improve the quality of products and reduce the production cost.

A thermosetting composition having:I. a curable polyester resin containing beta-ketoacetate moieties without vinyl unsaturations; andII. a phenolic resin having at least one methylol group.The curable polyester resin can be made by reacting a polyester resin with a compound containing a beta-ketoacetate moiety that does not contain a vinyl unsaturation such as alkyl acetoacetate compounds or diketene compounds.The curable polyester resin can be dispersed in water or dissolved in a solvent and is suitable for waterborne or solventborne coating compositions. Phenolic based crosslinking coating compositions that contain these curable polyester resins cure well with phenolic resin crosslinking compounds.

A filter medium for an air filter, characterized in that it comprises a filter material having a glass fiber as its primary component and an alkyl ketene dimer adhered to the surface of the glass fiber; and a method for producing the filter medium which comprises a step of subjecting a dispersed slurry of a raw material fiber to a wet papermaking to form a wet paper, a step of immersing the wet paper in an aqueous dispersion or solution of the dimer or a liquid mixture of the dimer and a binder resin, or applying or spraying any of the above-mentioned liquids to the wet paper, to thereby allow the dimer to adhere onto the surface of the glass fiber, and a step of drying the resultant wet paper having the dimer adhered thereto. The filter medium exhibits a reduced amount of an out gas generated when it is used with ventilation and also exhibits high water-repellency and satisfactory strength in various applications such as air conditioning of a building and semiconductor manufacturing.

The invention relates to a cooling method for rectification vacuum pump in ketene dimer production, wherein the method comprises the steps of: placing 25#transformer oil in an oil groove with cooling pipe, when the rectification vacuum pump is operating, pumping the 25#transformer from the oil cooler to the pump for cooling and sealing, combining the ketene dimer taken back from the bottom connected by the rectification vacuum pump to coarse ketene dimer section. The outlet gas of the rectification vacuum pump is pumped in tail gas absorber to spray and absorb ketene dimer. When acid content of circulating recycling liquid reaches 35-50%, the liquid is sent to glacial acetic acid for recycling, and residual carbon dioxide and nitrogen are pumped in the cracking still as fuel. The cooling method of rectification vacuum pump in ketene dimer production utilizes oil to replace water as cooling and sealing of vacuum pump, and uses soft water to absorb gases such as ketene dimer in the vacuum pump, which not only saves a great deal of water reduces emission, but also takes back ketene dimer to save resources and reduce environmental pollution.

The invention provides latex for papermaking. The latex contains starch, oxidants, hydrophobic modifying agents and water, wherein the dosage of the oxidants is 7-10% of the mass of starch; the dosage of the hydrophobic modifying agents is 5-20% of the mass of the starch; the hydrophobic modifying agents are selected from at least one of dodecenyl succinic anhydride, maleic anhydride, epoxy chloropropane, an alkyl ketene dimmer, alkenyl succinic anhydride, a styrene-acrylate copolymer, a silane coupling agent and a titanate coupling agent. The invention also provides a preparation method of the latex for papermaking and a coating containing the latex for papermaking. The problems that the wet strength of finished paper is poor and dusting happens easily because the paper is coated with the starch-based latex for papermaking in existing processes are solved.

The invention discloses a method for preparing amphoteric high molecular base AKD emulsion. The method comprises the following steps: under the function of a cosolvent and a molecular weight regulator, taking vinyl monomers, such as styrene, acrylate, acrylamide, a cation monomer, (methyl) acrylic acid and the like, as a copolymerization monomer and preparing amphoteric saponin-free benzene emulsion by a saponin-free emulsion polymerization method; taking the amphoteric saponin-free benzene emulsion as an amphoteric high molecular surfactant, emulsifying and dispersing a long-chain alkyl ketene multimer (AKD) with excellent hydrophobic property and preparing the AKD emulsion with favorable stability and sizing performance by shearing and dispersing. The invention does not use a small molecular emulsifying agent and cation starch in the preparation process and overcomes the defects of easy bubbling, poor stability, poor sizing effect and the like of the traditional AKD emulsion; the prepared amphoteric high molecular base AKD emulsion has anionic properties and cationic properties and is free from the interference of the anionic impurities of a papermaking wet part system, and the retention rate is greatly enhanced.

Additives for paper making are disclosed herein. Specifically, the additives are wax-free alternatives to conventional coatings, including ASA, AKD and optionally an acrylic containing composition. Other additives may be included in the coating, such as cationic particles or compositions. The coatings may be used at a variety of points during the paper making process, including on the calender stack and in the wet end.

Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable, and generate chemiluminescence rapidly on demand. The compounds and conjugates are useful in assays of an analyte in a sample and in assays employing labeled specific binding pairs.

The invention relates to a process for preparing high-purity diketene, which overcomes the defects of low purity of ketene, low purity and poor safety of diketene products formed by absorbing and polymerizing ketene, as well as complex process, high cost and high acetic acid content of raffinate in the concentration recovery of dilute acetic acid. The process for preparing high-purity diketene is suitable for absorbing and polymerizing ketene dimer at low temperature on the basis of adopting stable acetic acid cracking conditions and deep refrigeration to remove impurities from cracking gas and generate pure ketene gas, adopting a film evaporator to further purify diketene products at low temperature under low pressure, and adding stabilizers after introducing polymerization inhibitor and diketene for refining during the absorption and polymerization of ketene in order to improve synthesis safety and the stability of products in storage tanks. Meanwhile, the dilute acetic acid produced in the process reasonably matches the temperature of each point of a stripping section through a sensitive plate technique, improves the water-carrying capability of butyl acetate, and greatly reduces the concentration of acetic acid in concentrated raffinate.

A producing method of resin particles, which comprises at least an emulsification step of emulsifying a composition containing at least a polymerizable monomer and a polymerization step to form droplets of the composition, and a polymerization step of polymerizing the polymerizable monomer in the droplets to synthesize resin particles, wherein the composition is one selected from Composition A, Composition B, or Composition C: (Composition A): a composition containing a vinyl-based monomer, lactone, a vinyl-based monomer polymerization catalyst for polymerizing the vinyl-based monomer, and a lactone polymerization catalyst for polymerizing the lactone (Composition B): a composition containing a polyester resin, lactone, and a lactone catalyst for polymerizing the lactone (Composition C): a composition containing a vinyl-based monomer, a cyclic keteneacetal compound represented by the following general formula (1), and a radical polymerization initiator (in the general formula (1), R represents a chain or cyclic divalent aliphatic group optionally containing an ether linkage, and the aliphatic group may have a substituent.)

According to the present invention, the oxidation agent uses air or oxygen, or mixture gas of oxygen and inert gas, or other chemical oxidation agent, the reaction pressure is controlled to be 1-10 atm, the temperature being 20-150 deg. C, mu-oxygen single metalloporphyrin or double metalloporphyrin, or their carrier is separately selected as catalyst, or they form composite catalyst along with filtering metallic salts or oxidants, the catalyst concentration being 1-50PPM, reaction time being 0.5-5 hours, thus alpha, beta-enol, alpha, beta-ketene and epoxy compounds are obtained through catalytic oxidation of olefin or cyclomonoolefin.

The present invention discloses a novel synthetic method for F-acrylic acid and a derivative thereof. According to the process, ketene diethyl acetal with a molecular formula (2) CH2=C(OR1)2 is used for preparing 2-fluoride acrylic acid with a molecular formula (1) CH2=CF-CO2R and an ester thereof through a cyclopropane derivative with a molecular formula (3). According to the synthetic method disclosed by the invention, the synthetic method has the characteristics that the process is simple, the operability is high, raw materials used in preparation are cheap and the toxicity is low.

Disclosed is a packing material for a sheet recording material, which contains a paper material comprising an alkyl ketene dimer and cationic starch, the extraction pH of the paper material being within the range of 6.5 to 9.0. The packing material of the present invention suppresses generation of paper dust and prevents occurrence of white spot defect in recorded images on a sheet recording material even when the packing material is not subjected to surface treatment.

The invention discloses base paper for thermal transfer. The base paper is prepared from 100% of chemical pulp through pulping, papermaking, drying and curling. The base paper is characterized in that in the pulping step, 50-100% of bleached chemical staple fibers and 0-50% of bleached chemical long fibers are used and undergo pulp dispersion, pulp cleaning and defibrination to achieve fibrillation in the defibrination process; when chemicals are added, 0-20kg / ton paper of alkyl ketene dimmer, 0-2kg / ton paper of alkenyl succinic anhydrides and 70-500kg / ton paper of filler are added to the wet part and other functional auxiliaries are added according to the conventional quantity demanded; 0-20kg / ton paper of surface sizing agent is added to surface sizing starch; and the front calendering pressure and the rear calendering pressure are 10-30kg / cm in the curling process. The base paper has the advantages of higher bulk, suitability for various dye sublimation ink, no crease despite large width of transfer, good transfer effect, bright pattern colors after transfer and the like.

The invention belongs to the field of chemical production, and provides a method for continuously producing acesulfame potassium, which comprises the following steps: continuously mixing and dissolving sulfamic acid and dichloromethane, continuously neutralizing with a triethylamine solution, introducing the neutralized reaction solution and ketene dimer into a continuous reactor, and carrying outaddition acylation reaction to obtain a DKA reaction solution; sulfur trioxide and solvent micro-mixing: S03, enabling dichloromethane to enter a micro-mixer, so as to prepare a cyclizing agent; cyclization and hydrolysis: continuously feeding the DKA reaction solution and a cyclizing agent into a cyclization microreactor to generate a cyclization reaction solution, and continuously feeding the cyclization reaction solution into a hydrolysis microreactor to obtain an acesulfamic acid reaction solution; enabling the acesulfame acid reaction liquid and dichloromethane to enter continuous extraction equipment, enabling an extracted organic phase and a potassium hydroxide aqueous solution to enter a continuous neutralization reactor to obtain acesulfame acid potassium reaction liquid, and subjecting the acesulfame acid potassium reaction liquid to continuous concentration, continuous crystallization, continuous separation and continuous drying to obtain the acesulfame acid potassium finished product. The process has the characteristics of simple process, low cost, good product quality, continuous whole process and the like.

The present invention discloses a waterproof and damp-proof raw paper dedicated for electronic paper tapes, and a preparation method thereof. The method is characterized in that untwining and fibrillation are carried out on pulp fibers, fibrillation and cutting are further carried out so as to enable a pulp beating degree to reach 45 degree SR to 48 degree SR and a fiber wet weight to be reduced to 5.5 g to 8.0 g; and a water-resistant damp-proof composition is added in each layer, 1.0%-2.5% of the water-resistant damp-proof composition is added in relative to 100 parts of the pulp fibers, the water-resistant damp-proof composition including 0.15+-0.015 % of a wet strength agent PAE, 0.50+-0.05 % of gum rosin or an alkyl ketene dimer (AKD), 0.10+-0.01 % of silicon and fluorine type polymers, and 0.15+-0.015 % of ammonium zirconium carbonate. According to the above method, defibrination treatment is utilized, and a water-resistant damp-proof functional chemical is added in the pulp and coated on the surface of paper, surface water absorption and an edge permeation index of the raw paper are lowered than like products on the market, and water-resistance and damp-proofness of the raw paper are the best.

The invention discloses a method for preparing benzopyran derivative by choline chloride functional ion liquid catalysis. The method comprises the following steps of: carrying out catalytic condensation reaction on aromatic aldehyde, an active methylene compound and ketene dimethyl under normal pressure to obtain the benzopyran derivative by using the functional ion liquid based on choline chloride as the catalyst. The method for preparing benzopyran derivative by choline chloride functional ion liquid catalysis is simple to operate, high in yield, good in reusability of catalytic reaction system, gentle in reaction condition and good in industrial prospect.

Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block copolymers contain these bioerodible poly(ortho esters). These block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents.

The invention provides a process for making a sorbic acid. The process comprises: pyrolysis of acetic acid for producing high purity ketene with coke oven gas as a heat source, polymerization reaction of butenoic aldehyde and ketene gas to give a sorbic acid polyester and acid decomposition of sorbic acid polyester to obtain the sorbic acid, wherein the polymerization reaction of the butenoic aldehyde and the ketene gas, which is performed in a combined polymerization reactor comprising at least of a spray absorption reactor and a packed tower provided with a recycle pump outside continuously, comprises the steps that: fresh butenoic aldehyde and recycle feed from a tower bottom of the packed tower are delivered to the spray absorption reactor to form a sprayed material flow and to react with a low-temperature ketene gas absorbed by formed negative pressure into the reactor; the reaction materials flow into the tower bottom of the packed tower circularly so as to conduct further polymerization reaction of the unreacted ketene and the butenoic aldehyde contained in the material flow; one part of the materials from the tower bottom of the packed tower is used for the inner circulation of a reactor system, while the other part is recovered constantly for use in the next process, thereby realizing continuous production.