2 results about "Cyclobutanone" patented technology

The present application relates to a kind of methods for synthesizing corresponding alcohol by electrocatalytic hydrogenation of carbonyl compound, using flow electrolytic cell or split H-type electrolytic cell, adding carbonyl compound in cathode electrolyte, collecting liquid phase alcohol product at reaction output end.The carbonyl compound includes formaldehyde, acetaldehyde, acetone, n-propyl aldehyde, n-butyl aldehyde, n-pentanal, 4-hydroxy-2-butanone, diacetone alcohol, 2-pentanone, cyclobutanone, furfural and other carbonyl-containing compounds.Different types of electrolytic cell are used, and the iron-based electrocatalyst constructed has the characteristics of low cost, high activity and high selectivity.Compared with traditional thermal catalytic technology, the electrocatalytic hydrogenation of carbonyl compound to synthesize corresponding alcohol technology is carried out at room temperature and normal pressure, using water as hydrogen source, which not only reduces energy consumption and production cost, but also is green, safe and efficient, in line with the requirements of green chemical industry.

The application discloses a method for preparing a full-carbon quaternary carbon center derivative through radical-initiated olefin and alkyne cross-coupling, which overcomes the problem that a tertiary carbon radical generated in situ has a large steric hindrance and is difficult to react with a cross-coupling reagent to construct a full-carbon quaternary carbon center by using the guiding effect of a guiding group. The method uses 1,1-disubstituted electron-deficient olefin, O-(tert-butyloxycarbonyl) cyclobutanone oxime compound and terminal alkyne as raw materials, and reacts at room temperature under the presence of a catalyst, a base and a solvent in an inert atmosphere. After the reaction is completed, N-(pyridine-2-yl)-6-cyano-2-aryl-2-alkynyl hexanamide derivatives are obtained through separation and purification. The method has good substrate adaptability and simple operation advantages.