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33 results about "Thiosulfinate" patented technology
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In organosulfur chemistry, thiosulfinate is a functional group consisting of the linkage R-S(O)-S-R (R are organic substituents). Thiolsulfinates are also named as alkanethiosulfinic (or arenethiosulfinic) acid esters. They are the first member of a family of compounds containing an oxidized disulfide bond. Other members of this family include thiosulfonates (R-SO₂-S-R), α-disulfoxides (R-S(O)-S(O)-R), sulfinyl sulfones (R-S(O)-SO₂-R), and α-disulfones (R-SO₂-SO₂-R), all of which are known. The thiosulfinate group can occur in cyclic as well as acyclic structures.
Organosulphur prodrugs for the prevention and treatment of injectious diseases and pathologenic immune system response
ActiveUS20040235946A1Avoid difficultyUniform concentrationBiocideSulfur/selenium/tellurium active ingredientsDiseaseThiosulfinate
A method for enhancing the overall beneficial immune system response in a host that works in conjunction with the host's natural immune system response to simultaneously enhance the host's ability to eliminate infectious microbes while suppressing the toxicity of the immune system response to the host. The method utilizes the non-enzymatic formation of allicin in response to the localized generation of H2O2 by immune system cells (such as neutrophils) to simultaneously increase the antimicrobial effect while reducing the cytotoxicity to the host. It is shown that enzymes can be reversibly inhibited that would not normally be sensitive to deactivation by a thiol-disulfide exchange reaction. This results in part from the recognition that deactivation of SH dependant enzymes by allicin does not take place by the previously attributed mechanism of thiol-disulfide exchange reactions. Allicin, cysteine, and related organosulfur compounds have a variety of antimicrobial and immunomodulatory properties that work together with the host's immune system in the prevention and treatment of disease. Prophylactic and therapeutic treatment is provided by administering an allium-related organosulfur compound such that a localized thiosulfinate is caused to be non-enzymatically formed in response to localized generation of H2O2 by the activated immune system cells. Allicin, cysteine and related organosulfur compounds may be simultaneously delivered in an efficient manner through the use of protein-bound S-AllylMercaptoCysteine (SAMC) or similar prodrugs.
Owner:ALLIUM VITALS
Use of extracts and compounds of allium-genus plants as preservatives in the food and agri-food industries
The present invention relates to the use of extracts and compounds of plants from the Allium genus for the food and agrifood industry consisting of being used as food preservatives for humans and animals, plants being harvested or post-harvest plants, as well as for environmental disinfection, using thiosulfinates, thiosulfonates, ajoene, vinyl dithiins and products resulting from the decomposition of thiosulfinates.
Owner:MOUSALA
Method for synthesizing chiral sulfenamide
InactiveCN101525308AReduce dosageLower synthesis costOrganic-compounds/hydrides/coordination-complexes catalystsAsymmetric synthesesThiosulfinateSalicylaldehyde
The invention discloses a method for synthesizing chiral sulfonamide. In the method, chiral thiosulfinate is taken as a raw material and reduced with liquid ammonia containing lithium amide to obtain the chiral sulfonamide, and a reaction formula is as above, wherein, R is one of C1-C10 alkyl, phenyl, p-cresyl, o-cresyl, metal-cresyl, p-ethyl benzyl, p-tertiary-butyl phenyl, p-acetyl phenyl, o-acetyl phenyl and naphthyl. The method sequentially comprises the following steps: preparing the lithium amide; dropwise adding the lithium amide to chiral thiosulfinate solution and stirring for reaction; and adding ice to obtained mixture after the reaction, extracting, combining organic phases and eliminating solvents, and crystallizing to obtain the chiral sulfonamide. The method has the advantages that synthesis cost is reduced by an oxidation method in the presence of a chiral catalyst; a ligand is a condensation product of cheap and available chloromycetin derivative and salicylaldehyde derivative; and reaction steps are less, the reaction conditions are mild and post-treatment is simple.
Owner:上海立科化学科技有限公司
Personal care and medicinal products incorporating bound organosulfur groups
ActiveUS20060269488A1Low techSimple manufacturing processCosmetic preparationsToilet preparationsThiosulfinic acidsThiosulfinate
Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-microbial, anti-oxidant, anti-inflammatory, and anti-aging properties and are suitable for use without a prescription. The products utilize a biomembrane permeable organosulfur compound that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to oxidants and antioxidants inside and outside of cells. Example products include an anti-microbial toothpaste with anti-plaque properties, an anti-inflammatory skin lotion with antioxidant, antimicrobial, and deodorant properties, and an anti-toxin skin lotion with anti-arsenicosis properties.
Owner:ALLIUM VITALS
Method for synthesizing 7-phenylacetylamino-3-chloromethyl cephalosporin alkyl acid p-methoxybenzyl ester
InactiveCN101525340AFew reaction stepsSimple and fast operationOrganic chemistryPenicillinThiosulfinate
The invention belongs to the field of cephalosporin antibiotic medicaments, and in particular relates to a method for synthesizing 7-phenylacetylamino-3-chloromethyl cephalosporin alkyl acid p-methoxybenzyl ester (GCLE). The technical proposal is that the method comprises the following steps: reacting penicillin sulfoxide ester with ammonium benzene sulfinate and 2-mercaptobenzothiazole in dichloromethane, and steaming out a solvent at normal pressure to generate aza-cyclobutanone thiosulfinate intermediate; adding dichloromethane to the intermediate after cooling, stirring and introducing saturated brine ice for cooling, adding trichloro isocyanic acid for reaction so as to generate an allylic chlorination product of the aza-cyclobutanone thiosulfinate; and reducing the pressure and drying the allylic chlorination product by distillation, adding dimethyl formamide to the product, stirring and introducing saturated brine ice for cooling, adding ammonia for reaction, adding water and dichloromethane to the mixture, mixing and stirring the mixture, standing for layering, transferring a dichloromethane layer at the bottom layer to another reactor, and steaming out the solvent at the normal pressure to obtain a dry product which is the GCLE. The method has the advantages of mild reaction condition, few reaction steps, simple operation, short production cycle, and improved production efficiency.
Owner:SHANDONG FANGXING SCI & TECH DEV
Medicinal products incorporating bound organosulfur groups
Nutraceutical and dietary supplement formulations for delivering bioavailable thiols to a host, comprising certain organosulfur radicals, such as the allyl mercapto radical, bound to larger molecules such as proteins, resulting in the formation in the host's body of various allium-related compounds such as allicin. The formulations are produced by treating an ingestible material comprising a cysteine-containing protein with a thiol, disulfide, mixed disulfide, thiosufinate or mixed thiosulfinate so as to cause thiol residues to become disulfide bonded to cysteines contained in the protein.
Owner:ALLIUM VITALS
Preparation method of composite rich in ajoene
The invention discloses a preparation method of a composite rich in ajoene. The preparation method comprises the following steps of transforming natural alliin extracted from garlic into diallyl thiosulfinate by taking alliinase as a catalyst; carrying out membrane concentration, extraction, separation and enrichment, and then reacting and purifying to obtain a high-content ajoene product. The preparation method disclosed by the invention has the advantages of available process raw materials, easily controlled production process conditions and high product purity.
Owner:四川省荣桓科技有限责任公司
Synthetic method for preparing thiosulfonates on basis of sulfinic acid sodium salt disproportionated reaction
ActiveCN108586302AEasy to operateRaw materials are easy to getOrganic compound preparationSulfonic acid amide preparationThiosulfinateOrganic synthesis
The invention relates to a synthetic method for preparing thiosulfonates on the basis of a sulfinic acid sodium salt disproportionated reaction. The preparation method comprises the steps that sulfinic acid sodium salts serve as the raw materials, boron trifluoride diethyl etherate serves as accelerant, dichloromethane serves as solvent, and by means of a disproportionation coupled reaction, a thiosulfinate compound with good biological activity is synthesized; two different sulfinic acid sodium salts serve as the raw materials, and by means of a crossed disproportionation coupled reaction method, an asymmetric thiosulfinate compound can be synthesized. By means of a one-pot method and a two-step method, and by means of a thiosulfonates intermediate prepared on site, a sulfones compound and a sulfonamides compound can be synthesized by directly starting from sulfinic acid sodium salts. Accordingly, a synthetic route for preparing thiosulfonates on the basis of the sulfinic acid sodiumsalt disproportionated reaction is provided for the first time, operation is easy, raw materials are easy to obtain, the condition is mild, no metal catalyst is needed, no additional oxidant or reductant is needed, and the prepared thiosulfonates can have the good biological activity, and can also serve as the intermediate of the reaction to be applied to organic synthesis.
Owner:SOUTH CHINA NORMAL UNIVERSITY
Method for preparing gram-level high-purity natural thiosulfinate
The invention relates to a method for preparing gram-level high-purity natural thiosulfinate, belonging to the technical field of compound preparation. The method comprises the following steps: preparing an allium tissue homogenate containing active alliinase, keeping the temperature, washing off endogenous thiosulfinate generated in the tissue homogenate with an organic solvent, preparing exogenous ACSO into a solution, adding the solution into the tissue homogenate, keeping the temperature to generate single thiosulfinate or mixed thiosulfinates, and finally, purifying to obtain the product. The method has the advantages of mild reaction conditions, high product purity, high reaction yield, high cleanness and environmental protection, is simple to operate, and conforms to green technological requirements. The purity of the prepared pure thiosulfinate is sufficient for manufacturing drugs and especially diallyl thiosulfinate (garlicin). The research indicates that the garlicin has the maximum antibacterial, antihypertensive, anticancer, antioxidation and other activities in thiosulfinate.
Owner:JIANGNAN UNIV
Process of preparing conjugates of allium organosulfur compounds with amino acids, peptides, and proteins
ActiveUS20110082282A1Maximize yield and recoveryGood anti-inflammatory effectAlbumin peptidesTripeptide ingredientsThiosulfinateThiosulfinic acids
Owner:WISCONSIN ALUMNI RES FOUND
Method for preparing thioalkyl/alkenyl cysteine sulfoxide by fractional crystallization
ActiveCN104140384AHigh purityOptically activeOrganic chemistryOrganic compound preparationThiosulfinateBULK ACTIVE INGREDIENT
The invention discloses a method for preparing thioalkyl / alkenyl cysteine sulfoxide by fractional crystallization, belonging to the technical field of compound preparation. The method comprises the following steps: adding cysteine or cysteine salts, a sodium hydroxide solution and an R group (alkyl or alkenyl)-derived material into absolute ethanol in sequence for reaction to synthesize coarse ACSs, re-crystallizing ACSs, purifying, oxidizing to form ACSOs, and fractionally crystallizing to obtain natural dextrorotatory ACSOs, wherein the R group-derived material is replaced to synthesize different types of ACSOs in allium; enantiomers in racemes are separated by adopting the fractional crystallization method to obtain natural dextrorotatory ACSOs with optical activity. Compared with a conventional extraction method, the method has the characteristics that the yield and the purity are high, a conventional complicated extraction process is avoided, the product has the optical activity, and the physical property is close to that of natural extract; the product is used in the fields of health products, pharmaceuticals and the like, the effects of resisting bacteria and cancers, reducing blood fat and the like of ACSOs are brought into play, or the product serves as an intermediate such as an active ingredient-diallyl thiosulfinate for synthesizing allium.
Owner:JIANGNAN UNIV
Cleaning agent
InactiveCN106497684AStrong decontaminationGood chemical stabilityInorganic/elemental detergent compounding agentsBiocideThiosulfinateCleansing Agents
The invention belongs to the technical field of daily necessities, and relates to a cleaning agent. The cleaning agent is used for cleaning a smoke exhaust ventilator, solves the problems that the cleaning agent is not environment-friendly in application and has no effect of inhibiting and killing bacteria, and in addition, has the multiple effects of cleaning, descaling, and inhibiting and killing bacteria. The cleaning agent comprises the following components by weight: 2-6.5 parts of bactericide, 3-6.5 parts of an antibacterial agent, 8-10.5 parts of a surfactant, 5-8 parts of a water-soluble cosolvent, and 68.5-82 parts of deionized water, the bactericide is a mixture of chitosan, isothiazolinones, diallyl thiosulfinate and a folium artemisiae argyi extracting solution, the antibacterial agent is a mixture of a fructus arctii extract and liquid ozone, the surfactant is sodium dodecyl benzene sulfonate in a straight chain structure, the water-soluble cosolvent is a mixture of a water-soluble chilli extract and ethanol water with the volume ratio of 95%, the formula is simple, the preparation cost is low, the application environment is friendly, and the cleaning agent has an excellent economic benefit and a good market prospect.
Owner:QINGDAO HAICHENG INTPROP SERVICES CO LTD
Fruit fresh-keeping coating for corrugated paper box and preparation method of fruit fresh-keeping coating
InactiveCN107760111AImprove adsorption capacityEnhanced inhibitory effectAntifouling/underwater paintsPaints with biocidesWater bathsThiosulfinate
Owner:樊之雄
Grain storage method
InactiveCN106343013ASafe and effective sterilizationKeep safeBiocideEdible seed preservationGreen environmentThiosulfinate
The invention discloses a grain storage method comprises the following step: placing a fumigation agent below or / and around a grain pile under an environment at room temperature to 40 DEG C, wherein the fumigation agent is a mixture of a thiosulfinate type compound and a sulfo-sulphonate type compound. The grain storage method realizes safe and effective sterilization and disinfection for grains, and has the advantage of green environment friendliness; particularly, one-time treatment of various grains and various germs and moulds under the same fumigation environment can be realized; furthermore, no germ or mould reappears even if the grains subjected to fumigation treatment can be stored for at least half a year or longer in a granary environment or under a transportation condition; meanwhile, the method further has the advantages of simplicity in operation, low cost, large application range to grains, germs and moulds and the like, and has important value and far-reaching significance for safe and long-time storage of the grains.
Owner:SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI +1
Process of preparing conjugates of allium organosulfur compounds with amino acids, peptides, and proteins
ActiveUS8481284B2Maximize yield and recoveryGood anti-inflammatory effectTripeptide ingredientsPeptide preparation methodsBiological bodyThiosulfinate
Owner:WISCONSIN ALUMNI RES FOUND
Use of propyl propane thiosulfinate and propyl propane thiosulfonate for the prevention and reduction of parasites in aquatic animals
ActiveUS20150094381A1Reduce multipleBiocideSulfur/selenium/tellurium active ingredientsThiosulfinateAquatic animal
A method for reducing parasites in aquatic animals is provided. The method includes reducing a plurality of parasites infecting an aquatic animal by administrating to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. In yet a different embodiment, a method for reducing a plurality of parasites infecting an aquatic animal includes administrating to the aquatic animal a compound comprising and propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1. In even yet another embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTS. In a different embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTSO.
Owner:INVESTFOOD
Hot-adhesion-release polyacrylic acid pressure-sensitive adhesive and preparation method thereof
ActiveCN110452622AIncrease stickinessReduce viscosityMacromolecular adhesive additivesOrganic non-macromolecular adhesiveIsooctyl acrylateThiosulfinate
The invention discloses a hot-adhesion-release polyacrylic acid pressure-sensitive adhesive. The polyacrylic acid pressure-sensitive adhesive consists of the following components in parts by weight: 40-50 parts of isooctyl acrylate, 20-30 parts of methyl acrylate, 5-10 parts of hydroxyethyl acrylate, 10-30 parts of a mixed solvent, 0.5-2 parts of a thiol compound, 0.1-0.5 part of S-1-allyl(Z)-2-allyl thiosulfinate, 0.5-1 part of benzoyl peroxide and 0.1-0.3 part of mixed wax, wherein the mixed wax is a mixture of polyethylene wax, microcrystalline wax and montan wax. The mixed wax, namely thepolyethylene wax, the microcrystalline wax and the montan wax, is added for mixing, and the melting point of the montan wax is approximately 75-86 DEG C, so that the mixed wax mainly exerts functionsof melting at a high temperature, reducing viscosity and facilitating stripping; the polyethylene wax is common wax, and a degumming phenomenon occurs after the temperature is increased; and the microcrystalline wax has high viscosity, has ductility, is not fragile at a low temperature, and has functions of separating and precipitating the polyethylene wax and the melted montan wax at a high temperature. This series of wax allows the pressure-sensitive adhesive in the first embodiment to still be normally used after cooling from high temperatures.
Owner:INST OF NEW MATERIALS & IND TECH WENZHOU UNIV
Personal care and medicinal products incorporating organosulfur groups
InactiveUS20170071839A1Guaranteed continuous useWidespread manufactureCosmetic preparationsToilet preparationsThiosulfinic acidsThiosulfinate
Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-microbial, anti-oxidant, anti-inflammatory, and anti-aging properties and are suitable for use without a prescription. The products utilize a biomembrane permeable organosulfur compound that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to oxidants and antioxidants inside and outside of cells. Example products include an anti-microbial toothpaste with anti-plaque properties, an anti-inflammatory skin lotion with antioxidant, antimicrobial, and deodorant properties, and an anti-toxin skin lotion with anti-arsenicosis properties.
Owner:OTT DAVID MICHAEL
Thiosulfinate antioxidants and methods of use thereof
The present application provides compound of Formula Xwherein A is an optionally substituted aliphatic or an optionally substituted aryl, and B is a moiety that stabilizes the partial positive charge at the carbon adjacent the divalent sulfur. The compound of Formula X is useful as a reversible antioxidant in a variety of applications. Also provided are methods of synthesizing the compound of Formula X.
Owner:UNIVERSITION OF OTTAWA +1
Method for synthesizing 7-phenylacetylamino-3-chloromethyl cephalosporin alkyl acid p-methoxybenzyl ester
InactiveCN101525340BFew reaction stepsSimple and fast operationOrganic chemistryPenicillinThiosulfinate
Owner:SHANDONG FANGXING SCI & TECH DEV
A method of inhibiting the reproduction of miscellaneous bacteria in the process of spirulina cultivation by using di-primary/secondary alkyl thiosulfinate
ActiveCN112741090BAvoid pollutionEnhanced inhibitory effectBiocideOrganic chemistryBiotechnologyMicroorganism
Owner:JIANGNAN UNIV
Allium extracts
InactiveUS9707201B2Simple compositionIncrease contentAntibacterial agentsAntimycoticsThiosulfinic acidsThiosulfinate
Improvements in or relating to Allium extracts. In particular, improvements in or relating to extending the therapeutic half-life or duration of Allium extracts. The invention further relates to the synthesis of methyl methyl thiosulfinate in a mixture with varying molar or mass ratios depending on the reaction conditions, in particular from either methiin or alliin alone or a mixture of both. Methods of treatment methicillin-resistant Staphylococcus aureus are also provided. Also provided is a kit comprising methiin in a first container and alliin in a second container.
Owner:LEPTREX
Bacterial enzyme composition for preventing and treating root-knot nematode and preparation method of bacterial enzyme composition
PendingCN114806993AHigh activitySolve the defect of instability and easy degradationBiocideBacteriaBiotechnologyThiosulfinate
The invention relates to the technical field of biological medicines, in particular to a bacterial enzyme composition for preventing and treating root-knot nematode and a preparation method thereof. The method comprises the following steps: carrying out overexpression and integrated expression on a bacterial source S-alkyl-L-cysteine sulfoxide lyase LCC1 in bacillus subtilis; a bacillus subtilis overexpression strain is utilized, high-enzyme-activity protein is obtained through lactose induction in the fermentation process, enzyme is secreted out of cells, and enzyme dry powder is obtained through spray drying; bacillus subtilis is utilized to integrate and express strains, enzyme products which are continuously and stably expressed are obtained through the fermentation process, and microbial inoculum / enzyme dry powder is obtained through spray drying. The substrate and bacterial enzyme dry powder are compounded to form a product, so that in-situ catalysis of enzyme is realized to produce an insecticidal product diallyl thiosulfinate, and rapid killing and long-term control effects of root-knot nematode are realized. A plate inhibition experiment shows that the product has a 100% lethal effect on soil root-knot nematode, and the control effect on root-knot nematode of greenhouse and field crops is obvious.
Owner:SHANDONG UNIV
Use of propyl propane thiosulfinate and propyl propane thiosulfonate for the prevention and reduction of parasites in aquatic animals
A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.
Owner:INVESTFOOD
Use of propyl propane thiosulfinate and propyl propane thiosulfonate for the prevention and reduction of parasites in aquatic animals
A method for reducing parasites in aquatic animals is provided. The method includes reducing a plurality of parasites infecting an aquatic animal by administrating to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. In yet a different embodiment, a method for reducing a plurality of parasites infecting an aquatic animal includes administrating to the aquatic animal a compound comprising and propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1. In even yet another embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTS. In a different embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTSO.
Owner:INVESTFOOD
Method for inhibiting infectious microbe reproduction in spirulina cultivation process by using diprimary/secondary alkyl thiosulfinate
ActiveCN112741090AAvoid pollutionGood inhibitory effectBiocideOrganic chemistryBiotechnologyDisulfide bonding
The invention discloses a method for inhibiting infectious microbe breeding in the spirulina cultivation process by utilizing diprimary / secondary alkyl thiosulfinate, and belongs to the technical field of aquatic food cultivation and production. According to the present invention, the specific substituted primary and secondary alkyl groups in the diprimary / secondary alkyl thiosulfinate are matched with the disulfide bond, such that the effects of microbial growth inhibition and infectious microbe killing are achieved, and the significant inhibition effect on the growth and the reproduction of the infectious microbe during the spirulina production is provided; meanwhile, the diprimary / secondary alkyl thiosulfinate used in the method is easy to naturally degrade, can be decomposed into harmless degradation products after staying in the water body for 1-2 days, has no shadow on the ecological system of the water body, and provides a new means for solving the problem of infectious microbe pollution in the spirulina culture production process.
Owner:JIANGNAN UNIV
A kind of synthetic method of preparing thiosulfonate based on disproportionation reaction of sodium sulfinic acid
ActiveCN108586302BEasy to operateRaw materials are easy to getOrganic compound preparationSulfonic acid amide preparationThiosulfinatePtru catalyst
The invention relates to a synthetic method for preparing thiosulfonates on the basis of a sulfinic acid sodium salt disproportionated reaction. The preparation method comprises the steps that sulfinic acid sodium salts serve as the raw materials, boron trifluoride diethyl etherate serves as accelerant, dichloromethane serves as solvent, and by means of a disproportionation coupled reaction, a thiosulfinate compound with good biological activity is synthesized; two different sulfinic acid sodium salts serve as the raw materials, and by means of a crossed disproportionation coupled reaction method, an asymmetric thiosulfinate compound can be synthesized. By means of a one-pot method and a two-step method, and by means of a thiosulfonates intermediate prepared on site, a sulfones compound and a sulfonamides compound can be synthesized by directly starting from sulfinic acid sodium salts. Accordingly, a synthetic route for preparing thiosulfonates on the basis of the sulfinic acid sodiumsalt disproportionated reaction is provided for the first time, operation is easy, raw materials are easy to obtain, the condition is mild, no metal catalyst is needed, no additional oxidant or reductant is needed, and the prepared thiosulfonates can have the good biological activity, and can also serve as the intermediate of the reaction to be applied to organic synthesis.
Owner:SOUTH CHINA NORMAL UNIVERSITY
Use of propyl propane thiosulfinate and propyl propane thiosulfonate for the prevention and reduction of parasites in aquatic animals
ActiveUS20160205930A1Parasite can be reducedAvoid loweringOrganic active ingredientsBiocideThiosulfinateThiosulfinic acids
A method for reducing parasites in aquatic animals is provided. The method includes administering to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2 and also propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1, so that a combination of PTS and PTSO is administered to the aquatic animal resulting in the reduction of a plurality of crustaceans infecting the aquatic animal in response to administering the combination of PTS and PTSO to the aquatic animal.
Owner:INVESTFOOD
Preparation method of S-alkyl-L-cysteine sulfoxide with high purity and high conversion rate
PendingCN114874113AShorten the timeSimple methodOrganic compound preparationOrganic chemistry methodsThiosulfinateLyase
The invention relates to the technical field of biological medicines, in particular to a preparation method of S-alkyl-L-cysteine sulfoxide with high purity and high conversion rate. Comprising a first step of substitution reaction and a second step of oxidation reaction, and the substitution reaction comprises the steps of alkaline substance dissolution, thioether substance solid dissolution and the like. The oxidation reaction comprises the following steps: dissolving in a hydrogen peroxide solution, carrying out cold ethanol precipitation and the like. S-alkyl-L-cysteine sulfoxide is a natural substrate of plant source cysteine sulfoxide lyase, dialkyl thiosulfinate is formed after the enzyme reacts with the substrate, and the product has broad-spectrum antibacterial performance and is a natural antibiotic. When the method is used for preparing the substrate S-alkyl-L-cysteine sulfoxide, the preparation time is greatly shortened, and the conversion rate is higher than that of the conventional method. According to HPLC-MS (High Performance Liquid Chromatography-Mass Spectrometry) detection, the prepared substrate S-alkyl-L-cysteine sulfoxide is correct in molecular weight, a peak pattern is a single peak, no obvious impure peak exists, and the purity is high.
Owner:SHANDONG UNIV
Production method of plant compound beverage
InactiveCN110250387APreserve basic nutritional valueStable stateFood preservationNatural extract food ingredientsOrganic sulfide compoundThiosulfinate
The invention discloses a production method of a plant compound beverage. The production method has the advantages that burdock and corn stigma are used as the raw materials, the compound beverage is formed by corn stigma extract and burdock extract, modified chitosan immobilization complex enzymes are used as the clarifying agent to adsorb substances such as pectin and protein with negative charges in the beverage, adsorption of bioactive substances such as flavonoids is reduced, nutritional value keeping is achieved, protease catalyzes protein to hydrolyze, flocculent precipitation is avoided, recycling in process is achieved, and production cost is lowered; by adding black garlic powder, thiosulfinate is mainly formed, various decomposition and transformation reaction is generated to form various organic sulfide, the amount of oxygen which can be utilized is reduced, beverage browning is further inhibited, and the compounding of the trace black garlic powder and the corn stigma extract amazingly eliminates the earthy smell of the burdock.
Owner:XUZHOU COLLEGE OF INDAL TECH
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