425results about "Carbonyl group formation/introduction" patented technology

The invention relates to a catalytic composition comprising: a first component which is at least a component with one or more metals from groups 3A, 4A, 5A, 6A, 7A, 8, 1B, 2B, 3B, 4B; and a second component selected from (1) at least one ionic liquid which consists of a compound formed by cations and anions and which is a liquid at ambient temperature, (ii) a matrix to which the first component is bound or on which it is supported, and (iii) a combination of the two. The invention relates to the use of said catalytic composition in a method for the insertion of carbon dioxide into an organic compound and, preferably, a compound selected from epoxides, acetals and orthoesters. The invention also relates to catalytic compositions comprising said metallic compounds.

The invention relates to a preparation method of a benzaldehydes compound and a catalyst for the preparation method. The catalyst is composed of 0.01-90 wt% of metal grains and 10-99.99 wt% of mesoporous carbon carrier; the metal grains are selected from any two of Pd, Au, Ag, Pt, Ru, Rh, Ni, Cu, Fe, Co, Cr, W, Mo, Ti and Ta; the weight ratio of two types of the metal is 1: (0.01-100) and the average grain diameter of the metal grains is 1-100 nm; and the mesoporous carbon carrier is prepared from a heteroatom-doped mesoporous carbon material. The content of heteroatoms in the mesoporous carbon material is 0.01-80 wt%. The catalyst provided by the invention is stable for water, air and heat and has an excellent catalytic activity; particularly, the catalyst has a high selectivity when being used for catalyzing an alcohol oxidation reaction to prepare aldehyde or ketone. The preparation method of the benzaldehydes compound provided by the invention has the advantages of high conversion rate of raw materials and good selectivity of a target product.

An improved process of synthesis of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl-1H-benzimidazole (omeprazole) by oxidation of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole with 3-chloroperoxy-benzoic acid in ethyl acetate wherein omeprazole is poorly soluble, at a temperature between -10° C. and 5° C. is disclosed. The second step is a purification of the crude product by dissolution and reprecipitation of the final product.

The invention provides a method for preparing benzaldehyde or substituted benzaldehyde by catalytically oxidizing methylbenzene or substituted methylbenzene and relates to the field of chemical industrial material intermediates. The benzaldehyde or substituted benzaldehyde of a general formula (1) and relevant side products are prepared by using a substance containing ferroporphyrin, derivatives of the ferroporphyrin or relevant load as a catalyst, adding a proper cocatalyst according to requirements, and oxidizing methylbenzene or substituted methylbenzene by using oxygen-containing gases such as oxygen, air and the like. In the method, the reaction is performed at a certain temperature of between 25 and 250 DEG C and pressure of 0.1 to 2 MPa; the using amount of the catalyst is small, and is 1 ppm to 1 mass percent under a non-load condition and 0.1 to 10 mass percent under a load condition; and other solvents are not added, and if necessary, a certain amount of cocatalyst is added. The method has the characteristics of environmental friendliness and simple process.

The invention belongs to the field of catalysis and oxidization, and particularly discloses a method for preparing 1, 2-diketone by catalyzing and oxidizing alkynes. The method comprises the following steps: taking alkynes R1-C-C-R2 (acetylenic link exists between C and C) as a reaction substrate, taking one of TBHP, m-chloroperoxybenzoic acid and p-benzoquinone as a oxidant, taking one of dichloro (p-cymene) ruthenium (II) dimer, tri (triphenylphosphine) ruthenous chloride, ruthenium acetate, ruthenium dichlorophenyl (II) dimer, ruthenium trichloride, BINAP ruthenous chloride, dodecacarbonyltriruthenium and tricarbonyldichlororuthenium (II) dimer as a catalyst, taking one of iodine, iodine chloride, iodine bromide, potassium iodide, tetrabutyl ammonium iodide and potassium bromide as a cocatalyst, and taking 1, 4-dioxane as a solvent to react under 40 DEG C to 100 DEG C for 4 to 24 h to prepare the 1, 2-diketone. The method is economic, environmental-friendly and mild.

The invention provides a method for preparing aldehyde or ketone through the catalysed air oxidation of alcohol. Calculated by 5mmol of a reaction substrate, 1 percent to 8 percent of 2, 2, 6, 6-tetramethylpiperidine-oxygen free radical (TEMPO) or derivatives thereof, 4 percent to 20 percent of halide-containing compounds, 4 percent to 10 percent of nitrite or nitrite esters are taken as catalysts, 0.1MPa to 0.8MPa of oxygen or air is taken as an oxidizer, the reaction lasts for 1 hour to 36 hours at temperature of 0 DEG C to 80 DEG C and a series of alcohols can be oxidized into aldehyde or ketone with high selectivity. The method has the advantages of fairly cheap and safe reagent adopted, wide applicability of the reaction substrate, mild reaction conditions, convenient separation of products, no pollution to the environment, etc.

The invention relates to a preparation method for aldehyde or alkone, in particular to a method for preparing aldehyde or alkone by oxygen catalysis and alcohol oxidation under the mild condition. Themethod comprises the following steps: according to the 5 mmol of reaction substrate, 1-8 percent of 2,2,6,6-tetramethylpiperidine-oxygen radical (TEMPO) or a derivative thereof, 4-20 percent of halogen-containing compound and 4-20 percent of nitric acid or nitrate are taken as the catalysts, 0.1-0.8 MPa oxygen or air is taken as the oxidant, then the reaction is carried out for 1-36 h at the temperature of 0-80 DEG C, a series of alcohols can be oxidized into aldehyde or alkone with high selectivity, a catalyst TEMPO and the derivative thereof can be circularly and alternately used, the turn-over number (TON) is up to 800 and the cost is greatly reduced. The invention has the advantages of safer reagent with lower price, wider applicability of the substrate, mild reaction conditions, convenient product separation, no pollution to the environment, easy industrialization, and the like.

The invention relates to a catalyst for hydroformylation reaction and a preparation method of the catalyst. The catalyst comprises a rhodium complex and a novel bis-phosphoramidite ligand and is prepared by the rhodium complex and the novel bis-phosphoramidite ligand with molar ratio of 2:1-1:10 through mixed reaction. The catalyst can be applied to the hydroformylation reactions of compounds with unsaturated C-C double-bonded structure at any end position and can improve the yield of linear-chain aldehyde in a product, and the service life of the catalyst is remarkably prolonged.

The invention discloses a combined production method for substituted benzaldehyde, substituted benzyl alcohol and substituted benzoic acid. The method comprises the following steps: (1) oxidation: a step of continuously introducing substituted toluene, a catalyst and oxygen-contained gas into an oxidation reactor and carrying out reaction so as to obtain oxidation reaction liquid; (2) hydrolyzation: a step of allowing the oxidation reaction liquid to continuously enter a hydrolysis reactor, and continuously adding water into the hydrolysis reactor and carrying out reaction so as to obtain a hydrolysis reaction mixture; (3) liquid-liquid layering: a step of layering the hydrolysis reaction mixture so as to obtain an oil phase and an aqueous phase; and (4) separation of products: a step of subjecting the oil phase to distillation so as to respectively obtain incompletely-reacted substituted toluene, substituted benzyl alcohol and substituted benzaldehyde, and subjecting the aqueous phase to cooling, crystallizing and filtering so as to obtain filtrate and substituted benzoic acid. The combined production method provided by the invention has the advantages of high raw material conversion rate, few by-products, good selectivity of target products, greenness and environmental protection.

The invention discloses preparation methods and application of a mercapto MOFs (Metal-Organic Frameworks) photocatalyst UiO-66(SH)2 and a series of noble metal mercapto MOFs photocatalysts M/UiO-66(SH)2 (M=Au, Pd and Pt). The UiO-66(SH)2 is prepared based on a pre-functionalization strategy by using zirconium tetrachloride and 2,5-dimercapto-1,4-terephthalic acid as precursors and combining with a solvent thermal synthesis method. By utilizing the metal affine effect of a mercapto functional group on a ligand skeleton, a noble metal ion is anchored on the UiO-66(SH)2, so that an M/UiO-66(SH)2 composite photocatalytic material is successfully prepared. In a loading process, an inert atmosphere, the addition of a strong reducing agent or a heat treatment process is not needed; highly dispersed Au, Pd and Pt ions can be loaded on a UiO-66(SH)2 material through a simple mixing process only. The UiO-66(SH)2 and the M/UiO-66(SH)2 both show favorable activity in an experiment of photocatalytically selectively oxidizing benzyl alcohol.

The invention discloses a titanate nanotube composite type photocatalyst as well as a preparation method and application thereof. A metal ion doped titanate nanotube photocatalyst with the one-dimensiional tubular structure is obtained by using anatase TiO2 and metal ion acetate as raw materials through hydrothermal and an ion exchange method; in addition, the CdS/titanate nanotube composite type photocatalyst with the one-dimensiional tubular structure is obtained by using the anatase TiO2, Cd(NO3)2.4H2O and thioacetamide as raw materials through one-step hydrothermal. The titanate nanotube composite type photocatalyst is used for the photocatalytic selective oxidation of alcohols for the first time and has high catalytic efficiency. The titanate nanotube composite type photocatalyst is simple to prepare, is used for the selective oxidation of the alcohols by using visible light as driving energy and oxygen as an oxidizing agent and is beneficial to the sustainable development of environments and energy sources.

The invention discloses a method for preparing a 2-iodine amyl -2-ene-1,4-diketone derivative by adopting visible light catalysis. The method comprises the steps of adding allene, perfluorobutyl iodide, an additive and a photocatalyst as shown in a formula (I) to an organic solvent at the molar ratio of 1:(1-2):(1-2):(0.005-0.1), stirring under the conditions of an oxygen atmosphere, visible light illumination, room temperature and ordinary pressure for 10-20h, carrying out post-treatment on a reaction liquid to obtain a 2-iodine amyl -2-ene-1,4-diketone derivative as shown in a formula (II), wherein the additive is NaI, NH4I or KI; the organic solvent is ethanol, dichloromethane, benzene, methylbenzene, tetrahydrofuran or acetonitrile; the photocatalyst is selected from one of the following components: Ir(ppy)3, Eosin Y, Rose Bengal, [Ir(dF-CF3-ppy)2(dtbbpy)]PF6, [Ir(ppy)2(tbbpy)]PF6, Ru(bpy)3(BF4)2. The method is mild in reaction condition, simple in operation, high in selectivity and good in yield; a substituent group can be expanded; and visible light catalysis is adopted, so that the method has the characteristics of being free of pollution and environment-friendly. The formulas are as shown in the specification.

The invention relates to a preparation method of a monoatomic rhodium catalyst used for catalyzing alkene hydroformylation reaction to generate branched chain aldehydes and olefine aldehydes. Applications of the monoatomic rhodium catalyst are capable of realizing a whole new reaction approach, tandem of alkene hydroformylation reaction and aldol condensation reaction is realized without adding ofadditional acid or base, and one-step of production of branched chain aldehydes and olefine aldehydes from alkenes and synthetic gas is realized. The main active component of the monoatomic rhodium catalyst is rhodium; rhodium is dispersed on a carrier in atom grade; the mass amount of rhodium accounts for 0.005 to 2wt% of the total mass amount of the monatomic rhodium catalyst. The monoatomic rhodium catalyst is relatively high in catalytic activity and stability in alkene hydroformylation reaction; under the optimum reaction conditions, branched chain aldehyde product selectivity is 95% orhigher. The monoatomic rhodium catalyst is low in economical and environment cost; production separation is convenient; post-treatment is simple; and the application prospect is promising.

The invention provides a process for preparing higher alcohols and/or aldehydes and also mixtures thereof by catalytic reaction of ethanol, the reaction taking place in the presence of at least one catalyst, the catalyst comprising an activated-carbon substrate which is provided with at least one metal, and more particularly has at least one metal dope.

The invention relates to a method for preparing aldehyde or ketone compound by catalytic oxidation. The method comprises adding high-activity Ru-supported catalyst, water, mixed organic solvent and alcohol compound into a reactor; reacting under normal pressure at 30-100 DEG C for 1-12 hours while introducing oxygen or air; standing after the reaction is finished to automatically demix two phases of water and oil, wherein the catalyst is in the water phase; and separating the upper organic phase to obtain the aldehyde or ketone compound. The conversion rate of the alcohol compound is 10-100%, and the selectivity of the aldehyde or ketone compound reaches 100%. The method is characterized by simple process, low production cost, environment friendliness and easy separation and reutilization of catalyst.

The invention relates to the field of catalysis, in particular to a method for preparing aryl ketone through reacting aldehyde with aryl boric acid under the catalysis of a ruthenium catalyst. In the method, an organic phosphide is used as a ligand, potassium phosphate is used as alkali, pinacolone or acetone is used as an additive, toluene or/and water is (are) used as a solvent(s), aldehyde and aryl boric acid which are used as reaction substrates react at 95-100 DEG C for 10-24h in the presence of a ruthenium compound used as a catalyst to prepare aryl ketone, wherein the catalyst is one of [Ru(cymene)Cl2]2, [Ru(CO)3Cl2]2, RuH2(CO)PPh3, Ru2(OAc)4, [Ru(benzene)Cl2]2, Ru(S-BINAP)Cl2 or Ru3(CO)12. In the invention, the used catalyst has relatively low price and low toxicity, thereby reducing the preparation cost and being more environmentally friendly.

The invention provides a greening method for preparing aldehydes and ketones through the alcohol oxidation of a copper catalyst. The greening method comprises the following steps: taking copper salt as the catalyst, a single-tooth or double-teeth N ligand as the ligand and an organic nitric oxide compound as a co-catalyst, and performing the alcohol aerobic oxidation reaction in water-phase or organic solvent under the existence of alkali and air to prepare an aldehyde and Ketone compound. A copper catalyst system, which is low in cost, easy to obtain, low in toxicity and high in activity, is adopted in the greening method, air is used as an economic, safe and green oxidant, and under the mild condition of the indoor temperature air, the aldehyde and ketone compound is prepared through effective alcohol oxidation. The reaction condition is simple and mild, the operation is easy, the reaction conversion rate is high, the product separation and purification are simple, and the recovery rate is high. The requirement on the reaction condition is relatively low, and the greening method has a good research and industrial application prospect.

The invention discloses a method for oxidizing alcohol into aldehyde, ketone or carboxylic acid. The method utilizes a metal nitrogen heterocyclic carbine compound as the catalytic agent and oxygen in air as the oxidizing agent. The method comprises the steps of selectively oxidizing alcohol compounds into the aldehyde or the ketone efficiently and gently; and oxidizing alpha-hydrogen-free primary alcohol into corresponding carboxylic acid compounds efficiently under the heating condition.

The invention provides a method for transforming alpha-irisone, beta-irisone and ether and ester derivatives thereof into relevant ketenes, and then forming keto-alpha-irisone, keto-beta-irisone and ether and ester derivatives thereof by using pyridinium ionic liquid as a reaction medium, a simple copper salt or manganese salt or cobalt salts as a catalyst and tert-butyl hydroperoxide as an oxidant,. The catalyst and the reaction medium in the method can be recycled, and the method has the characteristics that the unique phase changes are presented along with reaction and separation, and the method has good selection and high yield when the reaction is carried out in homogeneous phases, and is convenient for operation and the recycling of the catalyst and the reaction medium when the separation is carried out in heterogeneous phase. Therefore, the method for synthesizing the keto-alpha-irisone, the keto-beta-irisone and the ether and ester derivatives thereof is an efficient and environmental-friendly method having the characteristics of high-efficiency reaction of the homogeneous phases and convenient separation of the heterogeneous phase.

The invention relates to a synthetic method of indanone substances, and particularly relates to a method for preparing 2,3-dihydro-1-indanone and a derivative thereof. The method comprises the following steps of: mixing benzene substituendum of which the structure is shown in a formula (I) with AlCl3/NaCl, dropwise adding 3-chloropropionylchloride under agitation, and reacting to prepare the 2,3-dihydro-1-indanone and the derivative thereof in one step, wherein R1 and R2 are H atoms, halogen atoms, C1-C10 alkyl, methoxyl, ethyoxyl or amino; dropwise adding 3-chloropropionylchloride at 0-40 DEG C, wherein the control temperature is 0-60 DEG C and the retention time is 0.5-3hours; carrying out Fuke acylation reaction, heating to 150-200 DEG C to keep for 0.5-4hours; and carrying out cyclization reaction, and hydrolyzing cyclization reaction products, wherein the hydrolysis temperature is 50-100 DEG C. Two steps of reaction are merged into a one-pot method. Thus, purifying, drying and packaging of a midbody are reduced; the allergy possibility is avoided; the usage amount of a catalyst is reduced; and the production cost is reduced, and the environmental pollution is also reduced.

The invention relates to a method of preparing alpha-aryl carbonyl compound. With the catalyst of four triphenylphosphine nickel or acetylacetone nickel ligand, the aryl boric acid, the alpha-halogenated carbonyl compound, the ligand and the additive are dissolved in toluene, and after reaction for 10 to 24 hours in 50 to 100 DEG C, the alpha-aryl carbonyl compound is obtained, wherein, the ligand is single-tooth phosphine ligand or double-tooth phosphine ligand; and the additive is absolute potassium phosphate or tri-potassium phosphate. The invention, which utilizes the catalyst with low cost, stable substrate, easy obtaining and gentle reaction conditions, can not only catalyze arylation of ester, amide and ketone, but also can be compatible with beta hydrogen, thereby greatly expanding the range of the substrate. Moreover, the invention possesses great application potential and can directly constitute the main framework of the steride.

The invention relates to a method for synthesizing an aromatic ketone compound and particularly relates to DES (Deep Eutectic Solvents) catalyzed Friedel-Crafts (F-C) acylation reaction methods. The aromatic ketone compound is synthesized from an aromatic hydrocarbon compound and an acylating reagent through F-C acylation reaction, and a DES (wherein the ratio of ZnCl2/ChCl is 2: 1) serves as a catalyst during reaction. According to the method, the DES (wherein the ratio of ZnCl2/ChCl is 2:1) serves as the reaction catalyst while serving as a reaction solvent; the process is simple, the stability is strong, no volatilization exists, and the catalytic activity is high; during reaction aftertreatment, acid is not required to be added, so that the method is simple, convenient and environmental friendly.