132results about "Rhodium organic compounds" patented technology

The invention provides a 1, 4-diaza-butanetriene compound as well as a synthesis method and application thereof, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: carrying out a first reaction on a compound 1 and a compound 2 in a solvent A, removing the solvent A after the reaction is finished, extracting with benzene or toluene, filtering, mixing with 12-crown ether-4, and stirring to obtain a compound 3; the synthesis method of the compound 3 provided by the invention is high in yield, simple to operate, mild in reaction, simple in required reaction condition control and high in speed. The obtained compound 3 has excellent stability and can be used for key intermediates in various organic reactions, such as preparation of alpha-diimine ligands.

The present invention relates to novel ligands of formula 1, wherein R1 is each substituted or unsubstituted alkyl, perfluoroalkyl, aryl or cycloalkyl; a cyano group; a sulfonyl-SO2-R10 wherein R10 = a C1-C5 alkyl group, a C5-C6 cycloalkyl group, a C5-C10 aryl group, each unsubstituted or substituted by a C1-C4 alkyl group or a C1-C4 perfluoroalkyl group; silyl-Si (R20R30R40), wherein R20, R30 and R40 are, independently of each other, a C1-C6 alkyl group or a C5-C10 aryl group, which are each unsubstituted or substituted by a C1-C4 alkyl group; r2 is each substituted or unsubstituted alkyl, cycloalkyl, adamantyl or aryl; r3, R4 and R5 are each alkyl, cycloalkyl or aryl, which may be unsubstituted or substituted; or at least two of R3, R4 and R5 are alkyl or alkyl ether bridges and form a heterocyclic ring together with the phosphorus atom, or wherein R3 and R6 and / or R4 and R7 and / or R5 and R8 form an alkyl or alkyl ether bridge together with the nitrogen atom to which it is attached form a heterocyclic ring; r6, R7 and R8 are alkyl or aryl, which may be unsubstituted or substituted, or form a heterocyclic ring, alone or together, with R3, R4 or R5 and the nitrogen atom to which it is attached; m, n and o are 0 or 1, with the proviso that at least one of m, n and o is 1, metal complexes thereof and use for catalytic purposes. # imgabs0 #

To provide novel compounds which deliver an increased yield in hydroformylation of olefins.SOLUTION: The invention provides compounds of formula (I) in the figure. (In the formula, R1 to R14 are each independently -H, -(C1-C12)-alkyl, or the like.)SELECTED DRAWING: None

The present disclosure is related to organic acceptor-donor-acceptor compounds as non-fullerene acceptors for use in organic photovoltaics.

Disclosed are compounds, particularly compounds capable of sensing and / or imaging glycans (such as sialic acid, etc., such as mono-sialic acid, di-sialic acid, tri-sialic acid, polysialic acid) and / or cancer cells and capable of distinguishing between cancer cells and normal cells. The compound is a d8 or d10 metal complex or a salt thereof. The metal complexes may bind to glycans (such as, for example, monosialic acid, disialic acid, trisialic acid, and polysialic acid, etc.) and / or cancer cells. The combination interaction induces the accumulation of the metal complex and the self-assembly of the supramolecules, thereby causing the change of the photophysical properties of the metal complex.

This invention discloses a recovery agent for recovering rhodium-phosphine complex catalysts, its preparation method, and its application. The recovery agent comprises a support and a modifier, wherein the modifier is selected from at least one of chitosan and its derivatives. The recovery agent provided by this invention is highly efficient and environmentally friendly, its preparation method is simple, the recovery of rhodium-phosphine complex catalysts is easy to operate, and energy consumption is low. It not only avoids the waste of precious resources, but also effectively reduces the industrial production cost of carbonyl synthesis when applied to carbonyl synthesis reactions.

The invention discloses a synthesis method of an azulene-based organic metal ring, which belongs to the technical field of catalyst synthesis and is characterized in that a binuclear compound 1 and an azulene-based organic ligand 2 are used as raw materials to synthesize an azulene-based organic metal ring 3 through a one-pot method. The cyclic metal compound with photocatalytic activity is synthesized by taking an azulene organic ligand as an initial raw material through coordination site regulation and control. Compared with reported azulene-based organic metal rings, the azulene-based organic metal rings synthesized by the method have the obvious advantages of mild reaction conditions, short reaction time, high yield, simplicity in operation, high photocatalytic efficiency and the like.

The invention belongs to the field of medicinal chemistry, and particularly relates to a targeted drug coordinated metal complex as well as a preparation method and application thereof. The metal complex prepared by the invention is a ruthenium (II), iridium (III) and rhodium (III) complex coordinated with a targeted drug, the original biological activity of the ligand is remarkably optimized and improved by virtue of the synergistic effect between central metal ions and the ligand, the specific binding capacity of the ligand with a tumor cell target spot is enhanced, and the tumor cell target spot is further enhanced. The metal complex has a broad-spectrum and efficient anti-tumor activity, the action range of the metal complex can cover multiple common tumor types including but not limited to liver cancer, kidney cancer, breast cancer, ovarian cancer or colorectal cancer and the like, and an important technical support is provided for developing novel anti-tumor drugs with multiple target points and low toxic and side effects. The complex provided by the invention is novel in structure and good in anti-tumor activity, and has a good application prospect in the field of anti-tumor drugs.

To provide a compound including ligands improving device performance.SOLUTION: For example, provided herein is an Ir complex compound with 2-phenylpyridine ligands with specific substituents on the pyridine rings, which is prepared as the formula in the figure.SELECTED DRAWING: Figure 1

The present invention relates to novel ligands of formula 1, their metal complexes and their use for catalytic purposes. In Formula 1, R1 is alkyl, perfluoroalkyl, aryl, or cycloalkyl, each of which is unsubstituted or substituted with cyano, sulfonyl: -SO2-R10 (R10 = C1-C5 alkyl, C5-C6 cycloalkyl, C5-C10 aryl, each of which is unsubstituted or substituted with C1-C4 alkyl or C1-C4 perfluoroalkyl), or silyl: Si(R20R30R40) (R20, R30, and R40 are, independently of one another, C1-C6 alkyl or C5-C10 aryl, each of which is unsubstituted or substituted with C1-C4 alkyl); R2 is alkyl, cycloalkyl, adamantyl, or aryl, each of which is substituted or unsubstituted; and R3, R4, and R5 are alkyl, cycloalkyl, or aryl. R3 and R6, and / or R4 and R7, and / or R5 and R8 together form an alkyl bridge or alkyl ether bridge which, together with the nitrogen atom to which they are attached, forms a heterocyclyl ring; R6, R7, and R8 are alkyl or aryl which are unsubstituted or substituted, or which, individually or collectively, form a heterocyclyl ring with R3, R4, or R5 and the nitrogen atom to which they are attached; and m, n, and o are 0 or 1, provided that at least one of m, n, and o is 1.

Tridentate platinum, palladium, and gold complexes of Formulas A-I and A-II and tridentate iridium and rhodium compounds of Formulas B-I, B-II, and B-III suitable for delayed fluorescent and phosphorescent or phosphorescent emitters in display and lighting applications.

The invention relates to tetraalkylammonium-tetra- or hexahydroxometallates such as tetraethylammonium hexahydroxoplatinate, (N(alkyl)4)y[M(OH)x], a method for the production thereof, and the use thereof for producing catalysts.

A catalyst including, as effective ingredient, a specified complex falling under the general theme represented by Formula (1) which contains bidentate ligand including aromatic heterocyclic 5-membered ring having 2 or more nitrogen atoms, or represented by Formula (2) which contains bidentate ligand including: aromatic heterocyclic 5-membered ring having 2 or more nitrogen atoms; and 6-membered ring having 1 or more nitrogen atoms, isomer or salt of the complex: where M1 and M2 denote iridium; X1 to X16 each independently denote nitrogen or carbon; R1 to R13 denote, hydrogen atom, alkyl group, or hydroxy group, provided that when Xi (where i denotes 13 to 16) is nitrogen, Ri is absent at position corresponding to the nitrogen; L1 and L2 denote CpMe5; Z1 and Z2 denote any ligand or are absent; and m and n denote positive integer, 0, or negative integer.

The invention discloses a bidentate phosphine ligand coordination metal catalyst as well as a preparation method and application thereof, and belongs to the technical field of catalysts. The metal atom M in the bidentate phosphine ligand coordination metal catalyst provided by the invention is specifically selected as Co or Rh, and the Co or Rh metal center has a promotion advantage on selective carbonylation of high-branch-chain olefin, so that the hydroformylation reaction speed of the high-branch-chain olefin is accelerated, the selectivity of the product is improved, and the yield of the product is increased. The conversion rate of isooctene can be up to 98%, and the generation selectivity of isononanal can be up to 99%; the preparation method of the bidentate phosphine ligand coordination metal catalyst and the preparation method of isononanal provided by the invention are simple and easy for actual production.

The present invention discloses a metal complex with FTO inhibitory activity, and also discloses a preparation method and application of the metal complex with FTO inhibitory activity. The metal complex of the present invention is obtained by CuAAC reaction of an alkynyl-modified FTO inhibitor and an azide-containing metal complex precursor, and the metal complex has good anticancer activity and FTO inhibitory activity, which can overcome the problem of poor target selectivity of a single FTO inhibitor, and can overcome the problem of large toxic side effects when a simple metal complex (precursor) is used as an antitumor drug or an antitumor drug component.

The invention relates to a preparation method of a rhodium-phosphine complex catalyst. The preparation method of the rhodium-phosphine complex catalyst comprises the following steps: providing an alcoholic solution of a bidentate phosphine ligand; in an inert gas atmosphere, sequentially dropwise adding an alcoholic solution of rhodium trihalide hydrate and a formaldehyde solution into the alcoholic solution of the bidentate phosphine ligand to obtain a premixed solution; and heating the premixed solution to a predetermined temperature, and reacting for a predetermined time to obtain the rhodium-phosphine complex catalyst. Wherein the bidentate phosphine ligand is one of molecules represented by a general formula (1): # imgabs0, R1 is selected from one of groups represented by a general formula (2.1), a general formula (2.2), a general formula (2.3) and a general formula (2.4): # imgabs1 # Ar1, Ar2, Ar3 and Ar4 are all aryl groups. The method is simple and easy to operate, the problem of tedious process does not exist, and the high yield of about 95% is achieved.

A compound including a first ligand LA of Formula I,is provided. In Formula I, moiety A is a monocyclic ring or a polycyclic fused ring system; moiety B is a polycyclic fused ring system having at least three rings; each of Z1 to Z4 is C or N; K is a direct bond or a linking group; each R substituent is hydrogen or a General Substituent defined herein; at least one RA includes a non-aromatic polycyclic group; LA is coordinated to a metal M; Z1 forms a dative bond with M; and Z2 forms an anionic bond to K. Formulations, OLEDs, and consumer products containing the compound are also provided.

Disclosed is an indole-functionalized bisphosphoramidite having a specific formula: A method for preparing a rhodium-ligand complex includes combining starting materials including (I) a rhodium catalyst precursor, (II) an indole-functionalized bisphosphoramidite, and, optionally, (III) a solvent.

The present disclosure generally relates to a process for separating one or more heavies from a hydroformylation reaction product stream in a hydroformylation process comprising a compound, a transition metal complex hydroformylation catalyst precursor composition, and a metal-monophosphite ligand complex catalyst. In one aspect, the present disclosure provides a compound of formula (I): 1 -R 5 are the same or different and are H or an alkyl moiety; R 6 H, alkyl, aryl, OR 7 , -N(R 8 )2, and O(CH2CH2) y OR 8 Part, R 7 is an alkyl or aryl moiety, R 8 is H, alkyl, or aryl moiety. [Formula 1] JPEG2024545133000025.jpg50170

The present invention relates to tetraalkylammonium tetrahydroxymetallates or hexahydroxymetallates, such as tetraethylammonium hexahydroxyplatinate (N(alkyl)4)y[M(OH)x], a method for preparing the same, and the use thereof for preparing catalysts.

The present invention relates to rhodium compounds of the formula (I) [(L1)2Rh]+k[A]k- (I), where L1 is a bidentate phosphor-organic ligand, in particular a chiral bisphosphine ligands, preferably a ligand of the formula (II) as described herein, such as (2R,3R)-bis(diphenylphosphino)butane or (2S,3S)-bis(diphenylphosphino)butane, and A is a rhodium carbonyl anion optionally containing n mono- and bidentate ligands L2 and n is 0, 1 or 2, in particular 0, k is 1, 2 or 3; wherein [A]k- in formula (I) is preferably an anion of the formula [Rh(CO)4-n(L2)n]-, where L2 if present, is a monodentate organic ligand other than CO or, if n = 2, two ligands L2 may together form a bidentate organic ligand. The present invention further relates to the use of the rhodium compounds of the formula (I) as catalysts in a selective catalytic hydrogenation of an α,β-unsaturated olefinic double bond of an α,β-unsaturated carbonyl compound.

A compound is disclosed that has a metal coordination complex structure having at least two ligands coordinated to the metal; wherein the compound has a first substituent R1 at one of the ligands' periphery; wherein a first distance is defined as the distance between the metal and one of the atoms in R1 where that atom is the farthest away from the metal among the atoms in R1; wherein the first distance is also longer than any other atom-to-metal distance between the metal and any other atoms in the compound; and wherein when a sphere having a radius r is defined whose center is at the metal and the radius r is the smallest radius that will allow the sphere to enclose all atoms in the compound that are not part of R1, the first distance is longer than the radius r by at least 2.9 Å.

The present disclosure provides N-heterocyclic carbene ligands, catalyst complexes thereof, and methods using same. The present disclosure further provides synthetic methods of preparing the N-heterocyclic carbene ligands and catalyst complexes disclosed herein.

An indole-functionalized bisphosphoramidite is disclosed which has a certain formula. A method for preparing a rhodium-ligand complex comprises combining starting materials comprising: (I) a rhodium catalyst precursor, and (II) the indole-functionalized bisphosphoramidite; and optionally (III) a solvent.

In one aspect, phosphine compounds comprising three adamantyl moieties (PAd3) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAd3 ligands are also provided for catalytic synthesis including catalytic cross-coupling reactions.

The application discloses a preparation method of acetylacetone dicarbonyl rhodium, hydrated rhodium chloride and rhodium sulfate. The preparation method of acetylacetone dicarbonyl rhodium comprises the following steps: under the condition of an inert atmosphere, complexing reaction is carried out between hydrated rhodium trichloride and a mixed solution A to obtain acetylacetone dicarbonyl rhodium; the mixed solution A comprises N,N-dimethylformamide, acetylacetone and a complexing promoter; the complexing promoter comprises one or more of sodium acetylacetone, sodium benzoate, phenol, benzyl dimethylamine, triethylamine, triethylenetetramine, triethanolamine and pyridine. The method has the advantages of mild reaction condition, environmental friendliness, high yield, low heat energy consumption and significant reduction of the generation amount of waste water.

The present invention provides an isocyanato rhodium (I) zwitterionic complex, a preparation method thereof, micelles, a nano-diagnosis and treatment probe, and an anticancer drug. The isocyanato rhodium (I) zwitterionic complex has a rhodium (I) atom as the metal center, an aromatic isonitrile and a 4-isocyanate as ligands, is hydrophobic and hydrophilic, and has near-infrared second-zone luminescence properties. It is mixed with PEGylated liposomes, and the PEGylated liposomes encapsulate the isocyanato rhodium (I) zwitterionic complex through hydrophobic-hydrophobic interactions to obtain isocyanato rhodium (I) zwitterionic complex micelles. The micelles have biocompatibility and stability, near-infrared second-zone luminescence imaging, and anticancer activity. The micelles can be used for nano-diagnosis and treatment probes and anticancer drugs, and have potential application prospects in the field of biomedicine.

A process for the manufacture of a complex of the formula [MHaI(R1R2C=CR3R4)2]2 with M = Rh or Ir; Hal = Cl, Br or I; and R1R2C=CR3R4 = a gaseous mono olefin with 2 to 4 carbon atoms, the process comprising the steps: (1) preparing an aqueous alcoholic solution of a MHaI3 hydrate salt, (2) reacting the dissolved MHaI3 hydrate salt with the gaseous mono olefin R1R2C=CR3R4 under formation of precipitated [MHaI(R1R2C=CR3R4)2]2, (3) optionally, cooling the reaction mixture obtained after conclusion of step (2) down to a temperature in the range of > 0 to 10 °C and keeping it there, and (4) collecting and drying the precipitated [MHaI(R1R2C=CR3R4)2]2, wherein the temperature of the reaction mixture during step (2) is kept in a range of 15 to 30 °C.