60 results about "Butyl lithium" patented technology

The invention belongs to the field of electronic materials, and particularly relates to a synthesis method of a high-purity metal complex precursor. Compared with a synthesis method in the prior art, the synthesis method provided by the invention changes a reaction route, substituted cyclopentadiene is prepared firstly, then the substituted cyclopentadiene reacts with butyl lithium and metal chloride in sequence to obtain a substituted cyclopentadienyl metal trichloride intermediate, and finally the substituted cyclopentadienyl metal trichloride intermediate reacts with lithium dialkylamino to obtain the substituted cyclopentadienyl metal trichloride. The target product substituted cyclopentadienyl tri (dialkylamino) metal complex is obtained, and the prepared product is high in yield and purity. The synthesis method provided by the invention is convenient for large-scale production in factories, improves the productivity, and meets the ever-increasing market demand.

The invention provides an organic cross-linking material. The organic cross-linking material comprises a polymeric monomer, an initiator and a cross-linking agent, the use amount of the initiator is 1-6% of the use amount of the polymeric monomer; the dosage of the cross-linking agent is 0.02%-0.10% of the dosage of the polymeric monomer, and the cross-linking agent is one or a combination of more of triethyl boron propylene diamine, triethyl lithium boride, triphenyl n-butyl lithium borate and sodium borate. According to the high-strength and low-rebound-rate sprayed concrete based on organic and inorganic crosslinking, after spraying, the organic crosslinking material is polymerized to form a three-dimensional network structure, and a concrete hydration product is filled in the three-dimensional network structure and is mutually crosslinked and tightly combined. Through connection of the net-shaped structure, all parts of the sprayed concrete are connected more tightly, the rebound rate is reduced, meanwhile, cracks in a concrete matrix are reduced, the compactness is increased, and the compressive strength of the sprayed concrete can be remarkably improved.

The present invention relates to a method for preparing 9,9-dioctyl-2-fluorene boric acid, industrial 2-bromofluorene, sodium tert-butoxide, n-hexane, 1-bromooctane and activating agent are added to a reaction bottle, reacted at room temperature for 1-3 hours, and then n-hexane, 1-bromooctane and activating agent are extracted in turn by vacuum distillation, and an equal amount of n-hexane solution is added again; the temperature is cooled to 40-80°C, n-butyl lithium is added, and stirred for 0.5-1 hour; trimethyl borate is added again, and stirred for 1-2 hours; after completion of the reaction, the temperature is controlled to be lower than 20-0°C, hydrochloric acid solution is dripped, reacted for 1-4 hours, and then warmed to 0-20°C for reaction for 3-6 hours; liquid separation, organic layer is washed with saturated salt water, and water layer is extracted 3 times with n-hexane; after the organic layers are mixed, the solvent is recovered by vacuum distillation; the filter cake is washed with deionized water to pH=6-7, and the finished product is obtained after drying. The present invention meets the production requirements of economic efficiency and high yield.

The invention provides a synthetic method of 2-(2-amino-5-bromo-benzoyl) pyridine, and belongs to the technical field of medicine synthesis. A one-pot boiling method is adopted, 2-cyanopyridine and 4-bromaniline are used as raw materials, BCl3 is used as a catalyst, dichloromethane is used as a solvent, a heat preservation reaction is performed for 5-25 hours at the temperature of-10 DEG C to 40 DEG C, and the product 2-(2-amino-5-bromo-benzoyl) pyridine is obtained through ethyl acetate extraction, anhydrous sodium sulfate drying and dichloromethane and petroleum ether recrystallization. According to the preparation method of the 2-(2-amino-5-bromo-benzoyl) pyridine, provided by the invention, butyl lithium with extremely high dangerousness does not need to be used, the reaction steps are simple, the yield is stable, the treatment is easy, and the yield is high.

The invention discloses a silylene ligand supported metal cobalt catalyst and a preparation method and application thereof, and belongs to the technical field of metal organic catalyst.The preparation method comprises the steps that indole and n-butyllithium serve as raw materials and are subjected to a deprotonation reaction in a tetrahydrofuran solvent at the room temperature, 2-lithium indole is obtained, a tetrahydrofuran solution of chlorosilylene is added at the low temperature, and the 2-lithium indole is obtained; and carrying out nucleophilic substitution reaction at room temperature, and substituting Li in 2-lithium indole with silicon in chlorosilylene to obtain the silylene ligand. The preparation method comprises the following steps: taking a silylene ligand and a cobalt complex as raw materials, carrying out ligand substitution reaction at room temperature in a tetrahydrofuran solvent, and substituting a ligand in the cobalt complex with the silylene ligand to obtain the metal cobalt catalyst supported by the silylene ligand. The prepared metal cobalt catalyst supported by the silylene ligand is used for catalyzing olefin hydrosilylation reaction, ultrahigh catalytic activity is shown, complete conversion of olefin is achieved, Markov products are obtained with excellent selectivity, and therefore the problems of cost and product selectivity in industrial production are solved.

The invention belongs to the technical field of chemical synthesis, and relates to a synthesis method of 2, 3-dimethoxybenzaldehyde. According to the invention, o-dimethoxybenzene reacts with butyl lithium in an organic solvent system, and butyl lithium is used as a strong base to'remove 'hydrogen atoms at specific positions in o-dimethoxybenzene molecules, so that an active intermediate 2, 6-dimethoxyphenyl lithium is formed. The intermediate has electronegative phenyl carbon anions, has relatively strong nucleophilic ability, and provides good reaction sites for subsequent formylation reaction, so that the yield of the target product 2, 3-dimethoxybenzaldehyde can reach a relatively high level, the purity of the target product 2, 3-dimethoxybenzaldehyde also reaches an industrial application standard, and the utilization rate of raw materials and the market competitiveness of the product are greatly improved.

The application discloses a method for synthesizing 1,7-dibromoisoquinoline, which comprises the following steps: under the condition of inert gas protection, isoquinoline is reacted with bromine in an aprotic solvent at a reaction temperature of-60 DEG C to-90 DEG C under the action of butyl lithium to obtain 1,7-dibromoisoquinoline. The application innovatively makes isoquinoline react with bromine under the action of butyl lithium to obtain 1,7-dibromoisoquinoline, the raw material used is low in price, the method has the characteristics of short reaction steps, short reaction time, high yield and the like, and is suitable for large-scale production.

The invention provides a kilogram-level preparation method of an organic photoelectric conjugated tin reagent, and belongs to the field of organic synthesis and organic photoelectric materials. The method comprises the following steps: in a dry 20L reaction device, dissolving a conjugated thiophene compound in tetrahydrofuran, keeping nitrogen positive pressure protection, dropwise adding a tetrahydrofuran solution of n-butyllithium and a tetrahydrofuran solution of trimethyltin chloride in a low-temperature reaction system, stirring for reaction, after the reaction is completed, standing for phase splitting, collecting an organic phase, drying, and concentrating filtrate to obtain the conjugated thiophene compound. And recrystallizing to obtain the organic photoelectric conjugated tin reagent. According to the method, efficient macro preparation of various conjugated tin reagents can be achieved, 1-1.2 kg of target products can be prepared through single-batch reaction, and the method has the advantages of being high in yield, easy and convenient to operate, low in cost, good in environmental friendliness and the like.

The invention discloses a kilogram-level preparation method of an organic photoelectric conjugated boron reagent, and belongs to the technical field of organic synthesis and organic photoelectric materials. A kilogram-level preparation method of an organic photoelectric conjugated boron reagent comprises the following steps: uniformly mixing aryl halide and tetrahydrofuran in an inert gas atmosphere to obtain a mixed system 1; placing the mixed system 1 in a liquid nitrogen environment, then dropwise adding a THF solution of n-butyllithium, and stirring to obtain a mixed system 2; and adding a boric acid ester compound into the mixed system 2 for reaction, and finally performing purification treatment to obtain a target product, namely the organic photoelectric conjugated boron reagent. The preparation method of the conjugated boron reagent is efficient, safe and capable of achieving large-scale production, has the advantages of being easy and convenient to operate, low in cost, high in yield, good in purity and the like, is suitable for various benzene series, thiophene, fluorene and other substrates, achieves kilogram-level stable preparation, solves the amplification problem, improves supply chain autonomy, and is suitable for industrial production. The application requirements in the fields of high-end medicines and materials are met.

The invention discloses a method for improving demulsification of SBR (styrene butadiene rubber) through polymerization reaction, and relates to the technical field of lithium batteries. Butyl lithium is used as an initiator to enable styrene and styrene-butadiene rubber to be subjected to polymerization reaction, and long-chain alkyl is introduced to improve the demulsification performance of the styrene-butadiene rubber; wherein the mass ratio of the styrene butadiene rubber to the styrene to the butyl lithium initiator is 100: (5-30): (1-5); preparing an emulsion from the modified butadiene styrene rubber and deionized water, mixing the emulsion with a semi-finished product slurry obtained by mixing and stirring carboxymethyl cellulose, graphite and conductive carbon black, coating the surface of a copper foil with the mixed slurry, and drying to obtain a negative pole piece; the negative pole piece has a good bonding effect in a stripping force test.

The invention discloses a method for preparing 3-fluoro-4-aminopyridine, wherein 4-halopyridine and ammonia water are used as raw materials to react in the presence of a copper catalyst to generate 4-aminopyridine, and then a substitution reaction is carried out with a fluorinated reagent in the presence of 1,10-phenanthroline, ZnCl2 and n-butyl lithium to generate 3-fluoro-4-aminopyridine. The route has mild reaction conditions, a short reaction route, low cost, good safety, and good industrial production application prospects.

The invention provides a phenyl phosphonic acid bis (o-isocyano-phenol) ester ligand which is prepared by the following steps: in an inert gas atmosphere, mixing a compound benzoxazole with anhydrous tetrahydrofuran, cooling to-95 to-65 DEG C, adding an n-butyllithium solution dissolved in an organic solvent, stirring at-95 to-65 DEG C for 0.5-4 hours, adding diphenylphosphoryl chloride, stirring at room temperature for 8-10 hours, filtering, washing, and drying to obtain the phenyl phosphonic acid bis (o-isocyano-phenol) ester ligand. Carrying out post-treatment on the obtained reaction liquid to obtain a phenyl phosphonic acid bis (o-isocyano phenol) ester ligand; compared with the most common organic dye photosensitizer, the copper-based photosensitizer prepared from the phenyl phosphonic acid bis (o-isocyano-phenol) ester ligand overcomes the defect that the catalytic activity of the organic dye photosensitizer is rapidly reduced under long-term illumination, and in addition, the organic dye photosensitizer is easy to generate an aggregation-induced quenching effect; the photosensitizer disclosed by the invention does not generate an aggregation-induced quenching effect; compared with an iridium complex photosensitizer which is commonly used at present, the cuprous photosensitizer provided by the invention is more environment-friendly.

Disclosed are a chiral multidentate ligand (I), a preparation, and an application thereof. In this method, compound (M1) is subjected to condensation with compound (M2) followed by amine deprotection in the presence of a deprotection reagent to obtain compound (M4). Compound (1) is subjected to deprotonation by butyl lithium and phosphorization followed by dimethylamino group substitution to produce compound (3). The compound (3) and the compound (M4) are reacted in the presence of triethylamine to produce chiral multidentate ligands.

The application belongs to the technical field of organic synthesis, and particularly relates to a kind of bromine-containing isoindoline-1-ketone compound and preparation method thereof.The preparation method of the bromine-containing isoindoline-1-ketone compound uses commercially available aldehyde-derived imine as raw material, is reacted with aryl bromide oxazoline compound under butyl lithium condition, and then is subjected to acid-mediated cascade cyclization process, to efficiently construct isoindoline-1-ketone skeleton.The isoindoline-1-ketone compound can be directly used as an organic catalyst, the N-H functional group remaining in the structure of the isoindoline-1-ketone compound has reactivity, can be coupled with other bioactive molecules as a key connection site, to construct functional derivatives, the amide carbonyl group thereof can be further reduced, to be converted into pyrrolidine structural unit, and the structure itself can be used as a catalytically active center, to expand its application in the field of catalysis.

The invention discloses a preparation method of a carboxamide triazole intermediate, which comprises the following steps: reacting (4-bromo-3, 5-dichlorophenyl) oxy) (tert-butyl) dimethylsilane with p-chlorobenzoyl chloride under the catalysis of a metal organic magnesium lithium complex, and removing a hydroxyl protecting group to obtain the carboxamide triazole intermediate. The activity of the metal organic magnesium lithium complex is far lower than that of the butyl lithium, the safety is higher, the whole reaction does not need to be carried out at an ultralow temperature, and the activity of the metal organic magnesium lithium complex is lower, so that small impurities generated by coupling are much less than those generated by using the butyl lithium; and when hydrochloric acid is used for deprotection, the purity of the product in the reaction liquid is increased by nearly 10%, the purification difficulty is greatly reduced, and the product yield is increased. The (4-bromo-3, 5-dichlorophenyl) oxy) (tert-butyl) dimethylsilane can also be obtained through self-preparation, the whole process route is simple, the reaction raw materials are easy to obtain, the synthesis cost is low, the reaction conditions are mild, and the safety is high.

The invention discloses a fully continuous synthesis method of MNI-137, which comprises the following steps: mixing an organic metal reagent solution with an ethyl acetate solution, and reacting I in a first microchannel reactor to obtain an enol intermediate; mixing the enol intermediate with a 2-cyano-4-methyl picolinate solution, carrying out a reaction II in a second microchannel reactor, and carrying out acid quenching and separation to obtain an organic phase; mixing the organic phase with a 1-Boc protected amino-2-amino-4-bromobenzene / triethylamine solution, and carrying out a reaction III in a third microchannel reactor to obtain an intermediate; mixing the intermediate with a trifluoroacetic acid solution, and carrying out a reaction IV in a fourth microchannel reactor to obtain MNI-137; the organic metal reagent is selected from at least one of lithium methide, n-butyllithium, sec-butyllithium, lithium diisopropylamide, lithium bis (trimethylsilyl) amide, sodium bis (trimethylsilyl) amide, potassium bis (trimethylsilyl) amide and potassium tert-butoxide.

The invention discloses a lithium ion conductor type lithium supplement agent, a composite positive electrode material, a positive electrode plate and a battery, and belongs to the technical field of batteries. The lithium ion conductor type lithium supplement agent comprises the following raw materials: a strong reduction organic lithium reagent and an inorganic solid electrolyte, the strong reduction organic lithium reagent comprises at least one of n-butyl lithium, tert-butyl lithium and naphthalene lithium; and the inorganic solid electrolyte is Li < 1.3 > Al < 0.3 > Ti < 1.7 > (PO4) 3. The lithium ion conductor type lithium supplement agent is an over-lithiated inorganic solid electrolyte, and no extra gas is generated when the lithium ion conductor type lithium supplement agent is used as the lithium supplement agent; after the lithium supplement function of the lithium supplement agent is exerted, residues still have good ion conduction capability, the cycle performance of the material can be improved, the capacity of the whole battery is effectively improved, the cycle life of the whole battery is effectively prolonged, and the lithium supplement method for the lithium ion battery is simple, convenient and efficient.

The present invention provides a viscosity-responsive TB-pyridine cyano vinyl derivative and its synthesis and application. The derivative is prepared by multi-step reaction using p-bromoaniline, paraformaldehyde, n-butyl lithium, 4-pyridine acetonitrile, etc. as raw materials. The structural formula is shown in the following derivative (6): #imgabs0# The product has a large Stokes shift (207 nm) in solution and has significant AIE properties. Compared with pure methanol, the fluorescence of 3 is enhanced by 5.3 times when methanol / glycerol = 1 / 9 (v / v), showing good viscosity response, easy entry into living A549 cells, and strong targeting ability to the endoplasmic reticulum (Pearson coefficient Pr = 0.75), with the potential to become an AIE-type endoplasmic reticulum viscosity-responsive fluorescent probe. The product has strong inhibitory ability against HpeG2 cells under both dark and light conditions (428 nm), indicating its potential for development as an anti-liver cancer drug.

The present invention relates to a process for the preparation of sparsentan comprising the steps of: a) reacting the compound of formula (IX) with the compound (XIV), in the presence of a base and optionally a catalyst to obtain the compound of formula (XV); b1) reacting the compound of formula (XV) with the compound PG-CI in the presence of a base to obtain the compound of formula (A), or alternatively b2) reacting the compound of formula (XV) with the compound RO-PG in the presence of P2O5 and / or an acid to obtain the compound of formula (A); c) reacting the compound of formula (A) with a butyl lithium solution and treating the obtained suspension with isopropyl pinacol borate to obtain the compound of formula (B); using the compound (B) for the preparation of sparsentan. Therefore, the process according to the present invention is very simple, effective and industrially applicable, and particularly cost-effective.

The present invention belongs to the field of pharmaceutical synthesis technology and specifically relates to a method for preparing an empagliflozin intermediate compound. The method uses 2-chloro-5-iodobenzyl bromide and (S)-3-(4-bromophenoxy)tetrahydrofuran as starting materials, reacting them under the catalysis of magnesium and 2,2,6,6-tetramethylpiperidinyl oxide to produce the empagliflozin intermediate compound (S)-3-(4-(2-chloro-5-iodophenyl)phenoxy)tetrahydrofuran. This process eliminates the need for n-butyl lithium, has a short synthetic route, is simple to operate, and is more suitable for large-scale industrial production.

The application provides a preparation method of a phosphoric acid detazolamide intermediate and phosphoric acid detazolamide, which has mild reaction conditions, avoids extremely low reaction temperature (below -70 DEG C), avoids the use of toxic tin reagents and extremely flammable butyl lithium, has low cost, can significantly improve yield and purity, and has the phosphoric acid detazolamide prepared by the method, the purity of which is not less than 99.6%, and the quality is stable after accelerated storage for 6 months.

The present invention relates to a method and device system for preparing a dialkylamino metal complex and a triguanidine metal complex. The preparation method provided by the present invention combines the regulation and control of reaction conditions to promote reactions that are favorable for product generation, reduce the occurrence of side reactions, avoid the defect of introducing metal impurities using n-butyl lithium, and avoid the generation of components such as lithium salts that are inconvenient for subsequent separation, thereby facilitating product purification. Moreover, the dialkylamino metal complex and triguanidine metal complex prepared by the present invention meet the purity requirements for precursor materials in integrated circuit manufacturing.

The invention discloses a Sn (II) catalyst and its preparation method and application, preparation method step: S1, skeleton molecule and solvent A are added to a reaction vessel, inert gas is passed through to exclude air, and the reaction vessel is placed in an ice bath to reduce the solution temperature to 0 DEG C, then n-butyl lithium is added, stirred at 0 DEG C for 30min, then stirred at room temperature for 30min to obtain solution A; S2, tin dichloride is dissolved in solvent B to obtain solution B, solution B is added to solution A, stirred at room temperature for 6 18h, then solvent C is added after solvent B is removed by vacuum distillation, and solvent C is extracted to obtain the target product, then solvent C is removed under reduced pressure to obtain Sn (II) catalyst. The Sn (II) catalyst can be used in the defluorination hydrogenation reaction of polyfluoroaromatics or the reduction reaction of nitroaromatics as a catalyst. Compared to traditional transition metal catalysts, the catalyst raw material is easy to obtain, simple to synthesize, and alternative transition metal catalysts can participate in organic synthesis reactions.

The invention discloses a thin-layer metal-phase tungsten disulfide positive electrode material for a high-rate zinc ion battery and an electrode preparation method and application, and relates to the technical field of zinc ion batteries. The method comprises the following steps: uniformly mixing alkali metal and tungsten disulfide, putting the mixture into a vacuum tube, and heating at 800-900 DEG C for 10-15 hours to obtain alkali metal intercalated tungsten disulfide powder; uniformly dispersing the tungsten disulfide powder of the alkali metal intercalation in a diluted potassium dichromate standard solution to obtain metal-phase tungsten disulfide powder; and dispersing the metal-phase tungsten disulfide powder into an n-butyllithium solution to obtain the thin-layer metal-phase tungsten disulfide positive electrode material. When the prepared thin-layer metal-phase tungsten disulfide is used as a positive active material, the thin-layer metal-phase tungsten disulfide, a diaphragm, a zinc ion aqueous electrolyte and zinc metal are used as a negative electrode to prepare an aqueous neutral zinc ion battery system containing the positive electrode, the diaphragm, the electrolyte and the negative electrode, and the aqueous neutral zinc ion battery system has the characteristic of high rate performance; and the material still has relatively high specific capacity and cycling stability under high current.

The application discloses a silicon-bin ligand supported metal cobalt catalyst and a preparation method and application thereof, and belongs to the technical field of metal organic catalysis. The application takes indole and n-butyl lithium as raw materials, and a deprotonation reaction is generated at room temperature in a tetrahydrofuran solvent to obtain 2-lithium indole. A chlorosilane bin tetrahydrofuran solution is added at low temperature, and a nucleophilic substitution reaction is generated at room temperature. Li in the 2-lithium indole is replaced by Si in the chlorosilane bin to obtain a silicon-bin ligand. The silicon-bin ligand and a cobalt complex are taken as raw materials, and a ligand substitution reaction is generated at room temperature in a tetrahydrofuran solvent. The silicon-bin ligand replaces the ligand in the cobalt complex to obtain the silicon-bin ligand supported metal cobalt catalyst. The silicon-bin ligand supported metal cobalt catalyst prepared above is used for catalyzing an olefin silicon hydrogenation reaction, exhibits super-high catalytic activity, realizes complete conversion of the olefin and obtains Markovnikov product with excellent selectivity, and thus solves the problems of cost and product selectivity in industrial production.

The invention relates to the technical field of cables, in particular to a cable waterproof insulating material and a preparation method thereof. The invention provides a preparation method of a cable waterproof insulation material, which comprises the following steps: synthesizing hexa (4-allylphenoxy) cyclotriphosphazene by using 4-allylphenol and hexachlorocyclotriphosphazene as raw materials; then, hexamethylcyclotrisiloxane, n-butyllithium and dimethylchlorosilane are subjected to a reaction, and single-ended active hydrogen polydimethylsiloxane is obtained; and finally, carrying out a reaction on the hexa (4-allylphenoxy) cyclotriphosphazene and the single-ended active hydrogen polydimethylsiloxane, so as to obtain the polysiloxane grafted cyclotriphosphazene. Polyethylene is selected as a base material and is subjected to melt blending with an ethylene-vinyl acetate copolymer, polyethylene grafted glycidyl methacrylate, polysiloxane grafted cyclotriphosphazene, magnesium hydroxide and calcium carbonate, and then a hot press molding process and high-energy electron beam irradiation are performed to obtain the waterproof, flame-retardant, wear-resistant and high-strength cable insulation material.

The invention discloses a flexural electrochemical driving material as well as a preparation method and application thereof, and particularly relates to the field of driving materials. Comprising the following steps: soaking a raw material in a butyl lithium solution of hexane, and leaching a solid-phase product; wherein the raw materials have intrinsic mechano-electrochemical coupling characteristics and mechano-electric coupling characteristics; mixing the solid-phase product with deionized water to obtain a mixed solution; filtering and drying a floating layer product of the mixed solution to obtain a lamellar material; depositing a metal film on the surface of the sheet material to obtain a flexural electrochemical driving material; wherein the metal film comprises a gold film, a silver film or a copper film. According to the flexural electrochemical driving material obtained based on the method, electric energy is converted into mechanical energy through electrochemical reaction under the action of a uniform electric field, and the driving function is achieved; and under the action of electric field gradient (non-uniform electric field), driving deformation is generated based on inverse flexoelectric response, so that the deformation response rate of the driving material is accelerated, and the deformation control precision is improved.

The invention discloses a rapid repairing material for a highway and a preparation method thereof, and relates to the technical field of pavement materials. The rapid repairing material for the highway is prepared from Portland cement, river sand, modified polyacrylonitrile fibers, a defoaming agent, a water reducing agent, modified basalt fibers, an acrylic emulsion and ammonium persulfate. The modified basalt fiber is obtained by carrying out a reaction on a pretreated basalt fiber and monohydroxy heptavinyl silsesquioxane; the modified polyacrylonitrile fiber is prepared by the following steps: reacting polyacrylonitrile with 5-azido-2-chloropyridine, spinning into fiber through wet spinning, reacting with n-butyllithium, and reacting with sodium cyanide. The rapid repairing material for the highway, prepared by the invention, has good mechanical properties, ageing resistance and antibacterial property.

The invention provides an organic dilithium compound, a preparation method thereof and hydroxyl-terminated liquid polybutadiene rubber. The preparation method comprises the following steps: in a protective atmosphere, mixing a solvent, a bromine-containing vinyl benzene compound A, a catalyst and piperazine, and carrying out reaction and post-treatment to obtain a product S1; under a protective atmosphere, mixing the product S1, cyclohexane and alkyl lithium, and reacting to obtain an organic dilithium compound; the molar ratio of the bromine-containing vinyl benzene compound A to the piperazine is (2-3): 1; the molar ratio of the product S1 to lithium alkyl is 1: (2.5-3.5); the lithium alkyl comprises one of n-butyl lithium, sec-butyl lithium and tert-butyl lithium; by mass, the use amount of the catalyst is 1%-5% of that of the bromine-containing vinyl benzene compound A. The organic dilithium compound has good solubility and activity in a non-polar solvent, and when the organic dilithium compound is applied to preparation of hydroxyl-terminated liquid polybutadiene rubber through anionic polymerization, butadiene monomer polymerization can be initiated at two ends, and the phenomenon of false gel is overcome.

The invention discloses a high-temperature resistant room-temperature curing silicone rubber and a preparation method thereof, relating to the technical field of silicone rubber, wherein the present invention is first prepared by reacting ferrocene with butyl lithium and tetramethylethylenediamine under nitrogen protection to form a multi-lithiated ferrocene lithium salt; hexamethylcyclotrisiloxane and 12-4 crown ether are subsequently added to react; a polymer containing silicon chlorine end groups is then extracted with toluene; finally, a final ferrocenesilazane cross-linking agent is obtained by reacting with ammonia gas, and after mixing with hydroxyl-terminated polydimethylsiloxane and white carbon black, the cross-linking agent is cured at room temperature to form silicone rubber. The room-temperature vulcanized silicone rubber cross-linking agent of the present invention significantly improves the thermal stability and antioxidant properties of silicone rubber by introducing ferrocene and silicon-nitrogen bonds. This novel cross-linking agent optimizes the high-temperature resistance of silicone rubber and allows it to be used in air without the need for an added antioxidant, thereby broadening its scope of application and extending its service life.