103 results about "Heptanone" patented technology

The resist according to the present invention includes any one of tetrachloromethyl tetramethoxycalix [4] arene and trichloromethyl tetramethoxycalix [4] arene. The resist including such kind of components is soluble in the solvent having less effect to worsen a working environment, namely, ethyl lactate (EL), propylene glycol monomethyl ether (PGME), propylene glycol monomethyl ether acetate (PGMEA), ethyl propionate, n-butyl acetate and 2-heptanone. It can be developed by tetra-methyl ammonium hydroxide in addition to the above mentioned solvent. By exposing this resist by electronic ray, high resolution of 8 nm is attained, and by using this resist as a mask, various materials can be formed into a hyperfine shape. According to such kind of resist, a photosensitive resist material which has high resolution and solvable to solvents having less effect to worsen the working environment and can be developed by the solvents, a exposure method using it, and a hyperfine processing method using it are provided.

Provided are methods of forming photolithographic patterns using a negative tone development process. Also provided are coated substrates and electronic devices formed by the methods. The methods find particular applicability in the manufacture of electronic devices. The method includes: (a) providing a substrate comprising over a surface thereof one or more layer to be patterned; (b) applying a layer of a photoresist composition over the one or more layer to be patterned, the photoresist composition comprising a resin comprising an acid cleavable group and an acid generator; (c) patternwise exposing the photoresist composition layer to actinic radiation; and (d) applying a developer to the photoresist composition layer, wherein unexposed portions of the photoresist layer are removed by the developer, leaving a photoresist pattern over the one or more layer to be patterned. The developer comprises 2-heptanone and / or 5-methyl-2-hexanone.

The invention discloses a milk flavor formula. The milk flavor formula mainly comprises the components of propylene glycol, butyric acid, octanoic acid, capric acid, ethyl lactate, vanillin, maltol, delta-decalactone, delta-dodecalactone, gamma-dodecalactone, ethyl butyrate, butanedione, 2-heptanone, a milk-favor reactant and the like. Compared with other milk flavor, the milk flavor prepared by the milk flavor formula has a more natural taste and remarkably increased aroma and smell, enables the stability and the aroma quality to be higher than those of similar domestic flavor, is used as a food additive, is used for increasing taste of end products of foods and beverages, moreover, can bring more natural milk aroma and taste to a product, endows the product with natural taste, and can enable the heat resistance, the aroma quality and the stability of the product to be higher than those other similar domestic products at the same time.

The invention relates to a method for removing hexaldehyde and 2-heptanone in cyclohexanone. As a traditional technology for producing chemical fibre level cyclohexanone of caprolactam has the problems of high energy consumption and high material consumption, the invention discloses a method; the method comprises the following steps of: using solid adsorben to remove hexanal and 2-heptanone impurities from solvent-based cyclohexanone; controlling the content of the two in the cyclohexanone to be lower than 40mg / kg, and using supercritical gas carbon dioxide to desorb the adsorbate, so that the absorption and the desorption can be continuously on-line. The method has the characteristics of low energy consumption and low material consumption.

The invention discloses a process for preparing cyclohexanone by cyclohexanol dehydrogenation. Equipment for a cyclohexanol dehydrogenation procedure comprises a normal pressure or pressurized rectifying column and a cyclohexanol dehydrogenation reactor, the rectifying column is only provided with a stripping section, a column reactor is provided with a reboiler, and a cyclohexanone evaporator and a gas-liquid separator are sequentially arranged in the cyclohexanol dehydrogenation procedure. The process is used for a 100 thousand ton / year cyclohexanone production device, the concentration of methyl cyclohexanone, heptanone and analogues of the methyl cyclohexanone and the heptanone among materials in a cyclohexanone rectifying procedure and the cyclohexanol dehydrogenation procedure can be reduced from 10-13% to 1-2%, so that side reaction of dehydrogenation reaction is decreased, the quality of cyclohexanone products is improved, the service life of cyclohexanol dehydrogenation catalysts is prolonged, circulation and accumulation of the methyl cyclohexanone, the heptanone and the analogues of the methyl cyclohexanone and the heptanone in the cyclohexanone rectifying procedure and the cyclohexanol dehydrogenation procedure are decreased, and steam consumption is also greatly reduced.

The present invention relates to an organic matter synthesis method, particularly to a novel methyl heptanone synthesis method, wherein isovaleraldehyde and acetone are adopted as raw materials and are subjected to an aldol condensation reaction and a hydrogenation reaction through a one-pot method under catalysis of catalysts such as triethylamine and palladium carbon to synthesize the methyl heptanone, a small amount of the by-product methyl isobutyl ketone is subjected to distillation recovery, the recovered product is supplied for other positions, and the catalyst used in the reaction process can be repeatedly applied after being recovered. According to the present invention, the method has characteristics of easy operation, high reaction yield, energy saving and environmental protection, and is suitable for industrial production.

The invention discloses a black soybean milk flavor and a preparation method and an application thereof. The flavor comprises isovaleric aldehyde, methyl alcohol, isopentyl alcohol, hexanal, 2-methylpyrazine, furfural, trans-2-hexenal, furfuryl alcohol, hexyl alcohol, 2-heptanone, heptanal, 2-acetylfuran, 2, 5-methylpyrazine, 2, 3-dimethyl pyrazine, trans-2-heptenal, 5-methyl-furfural, benzaldehyde, heptanol, 1-octen-3-alcohol, 2-pentyl-furan, caprylaldehyde, 2-acetyl thiazole, trans-2-octenyl aldehyde, octanol, nonanal, capraldehyde, trans,trans-2,4-nonadienal, trans-2-decenal, 2-undecanone,trans,trans-2,4-heptadienal, trans-2-undecenal and propylene glycol. The method comprises the following steps: evenly mixing the above constituents, stewing and curing for 15 days, subpackaging to obtain the black soybean milk flavor. The flavor has convenient raw materials sources, mild fragrance and high naturalness, and is applied to preparing the beans products, is especially used for preparing black soybean milk beverage, not only can enhance mouthfeel, but also can better cover soil mildewed flavor brought by beans in basic materials.

The invention provides a traditional Chinese medicinal effective part for decreasing uric acid as well as a preparation method and application thereof. The traditional Chinese medicinal effective part is total flavone and a diphenylheptane diarylheptanoid obtained by being extracted and separated from alpinia officinarum hance, and is prepared from the following components of 35wt% to 80 wt% of galangin, 5wt% to 14wt% of galangin-3-O-methyl ether, 1wt% to 7wt% of kaempferol-4'-O-methyl ether and 2wt% to 10wt% of 1-phenyl-7-(3'-methoxyl-4'-hydroxyl)-5-ol-3-heptanone; the sum of the components does not exceed 100 percent. The effective part prepared and obtained by the preparation method provided by the invention is definite and is high in purity. According to the whole preparation method, except for ethanol, other organic solvents are not used; the preparation method is environment-friendly and pollution-free. The industrialized mass production is easily realized in the whole production process. In-vitro and in-vivo pharmacodynamic experiments and preliminary clinical experiments all show that an alpinia-officinarum-hance effective part prepared and obtained by the preparation method provided by the invention has an obvious uric acid decreasing effect. The traditional Chinese medicinal effective part has a quite good effect on a patient suffering from hyperuricemia or gout.

The present invention discloses a cheese flavor containing food additive as well as a preparation method and application thereof. The cheese flavor containing food additives comprise the following components in mass percentage: 0.1-0.5% of 3-methylthiopropanal, 0.1-1% of 3-methylthio-propanol, 0.1-0.5% of 2-undecanone, 0.5-1% of 2-heptanone, 0.1-0.5% of 2-nonanone, 10-15% of anhydrous butter hydrolysates, 0.1-1% of ethyl vanillin, 1-2% of vanillin, 0.1-0.5% of delta-decalactone, 1-5% of butyl butyryl lactate, 0.8% of delta-dodecalactone, 0.3-0.6% of ethyl laurate, 0.01-0.1% of ethyl acetate, 0.1-0.5% of ethyl caprate, 0.1-0.5% of oleic acid, and 70-85% of soybean oil. The addition of the anhydrous butter hydrolysates enables the cheese flavor containing food additives to be richer and more delicate in aroma. When the anhydrous butter hydrolysates are added during the food production process, the resulting product is lifelike and natural in cheese fragrance, and is excellent in mouthfeel. The food additives are zero trans-fatty acids which can meet the dual demands of people for delicacy and fitness.

The invention provides brown sugar essence for food and a preparation method of the brown sugar essence. The brown sugar essence mainly comprises, by weight, 0.4% of furanone, 0.1 of beta-Ionone, 1.4% of beta-damascone, 0.02% of alpha-damascone, 0.02% of methyl furoate, 0.05% of menthol, 0.2% of 5-methyl furfural, 0.02% of glacial acetic acid, 0.04% of 3-hydroxy-2-butanone, 0.02% of 2-heptanone, 0.45% of n-propyl alcohol, 0.025% of acetaldehyde sweet orange oil liquor of 40%, 0.35% of sugar lactone of 3%, 0.25% of n-pentanoic acid, 45% of glycerol and 51.655% of propylene glycol. The volatile fragrance of the whole brown sugar essence is sweet, naturality is high, body fragrance and fullness are achieved, and the base fragrance lasts long. The brown sugar essence can be applied to various kinds of food needing brown sugar flavor and can meet increasing material culture life requirements of people.

The invention provides a technique for preparing MIBK (methyl isobutyl ketone) from acetone with a liquid-phase one-step process. The technique comprises the following steps: hydrogen and acetone are fed into a reactor and subjected to a reaction under catalysis of gamma-Al2O3 doped hydrogen-type polystyrene cation exchange resin, and a product is delivered to an acetone recovery tower for separation; organic light components in the recovery tower are delivered to a wastewater tower, acetone is delivered back to the reactor, and heavy components at the tower bottom are delivered to a water removal tower; light components at the top of the water removal tower are delivered to an extraction tower, and a reaction product at the tower bottom is delivered to a finished product tower; purified water is adopted as an extracting agent in the extraction tower, and heavy components are delivered to the wastewater tower; MIBK is produced from a side line of the finished product tower, 2,6-dimethyl-4-heptanone and high-class ketone are produced from a tower bottom liquid. The technique is short in flow and low in energy consumption, 2,6-dimethyl-4-heptanone is co-produced, few noble metal palladium active components in a palladium supported resin catalyst are lost, stable service life as long as 7,000 h is realized, and the production cost is reduced.

The invention discloses an extracting method of diaryl heptanes compound from lesser galangal, which comprises the following steps: extracting lesser galangal through alcohol; condensing filtrate; dissolving the concrete through water; extracting through trichloromethane; separating the extract liquid through silica gel column chromatography method; eluting through ligarine-phenyl-methyl acetate gradient to obtain 33 compositions; combining 10th and 11th compositions; proceeding silica gel column chromatography and eluting chloroform-carbinol; combining similar compositions through TLC to obtain six compositions; proceeding Toyopearl HW-40C column chromatography for 3rd composition to obtain six compositions; preparing HPLC for the second composition at inversed-phase; eluting through 95:5 carbinol and water; separating to obtain 2 compositions with 7-(4- hydroxyphenyl)-1- phenyl -4-alkylene-3- heptanone.

The invention discloses 5-hydroxy-1, 7-diphenyl-3-heptanone separated from galangal and application of the 5-hydroxy-1, 7-diphenyl-3-heptanone. After the 5-hydroxy-1, 7-diphenyl-3-heptanone is intervened, sugar tolerance is obviously improved, and the effect of the 5-hydroxy-1, 7-diphenyl-3-heptanone on improving IR is obvious. The compound can up-regulate the transcriptional level of Nrf2 mRNA and downstream target genes.

The invention relates to a method for preparing ketone compounds. According to the method, an ABE fermentation solution (acetone-butanol-ethanol water solution) is adopted as a reactant, and the ketone compounds are prepared through a reaction under catalysis of a cerium-based composite oxide. The reaction conditions are as follows: the reaction is carried out at normal pressure in a fixed bed reactor, a reaction temperature is 350-500 DEG C, and a feeding mass space velocity of the ABE is 0.1-2.0 h<-1>. The method is characterized in that the cerium-based composite oxide is used as the catalyst, the catalyst is simple to prepare and has good stability, the ketone compounds are generated through efficiently catalyzing the ABE, the conversion rate is up to 95% (based on the total carbon number), and the total selectivity of the ketone compounds can reach 99%, wherein the selectivity of 4-heptanone is 92%, and the selectivity of 2-pentanone is 8%.

The invention relates to an efficient synthetic method of a natural product harringtonine intermediate with D-ring. A raw material of N-acyl-3,4-methoxy methylene benzo-3-N-heterocyclic heptanone is subjected to three steps including deacylation, N-C acylation and carbonyl alpha-site alkylation to complete construction of the D-ring of harringtonine, namely 3,4-methoxy methylene benzo-3-N-heterocyclic heptanone and ketopyrrolidine. Products from each step can be purified by a recrystallization method, and the method has simple operation, total yield reaching 81% and good industrial prospect.

The invention discloses a migratory locust nymph attractant as well as a lure and application thereof. The migratory locust nymph attractant is prepared from 2-heptanone and paraffin oil, the lure ofthe migratory locust nymph attractant is prepared by the following steps: uniformly mixing the paraffin oil with the 2-heptanone to obtain the migratory locust nymph attractant; soaking the rubber strip in the migratory locust nymph attractant for 1-2 hours, drying the rubber strip in the shade, and sealing the rubber strip with plastic to obtain the lure. The attractant is a preparation capable of adjusting migratory locust behaviors and can be used for controlling the migratory locust behaviors and preventing, controlling and monitoring migratory locust population quantity dynamics. 2-heptanone is a migratory locust metabolite, so that the attractant has no toxic effect on the environment and human, livestock and poultry, is safe to natural enemies, and belongs to a natural pesticide.

The invention relates to an artificial synthetic method of a harringtonine C-ring intermediate. According to the method, 3,4-methylenedioxyphenethylamine (compound I) as a raw material is subjected to acylation in alkaline conditions to obtain N-acylated-3,4-methylenedioxyphenethylamine (compound II), which is then reacts with halogenated acetic acid or halogenated acetic acid derivative to generate N-acylated-3,4-methylenedioxyphenethylamine acetic acid (compound III); and the compound (III) is catalyzed by Lewis acid to generate intramolecular Friedel-crafts acylation reaction to obtain N-acyl-3,4-metheneoxybenzo-3-N-cycloheptanone, namely C ring of harringtonine. In the preparation process, products of each step are purified by washing and recrystallization; and the method has simple operation, total yield of 87.4%, and good industrial prospect.

The invention discloses a synthetic method of N-(hept-4-yl) benzo [d] [1, 3] dioxole-5-methanamide. The step comprises the 3 steps of: mixing 4-heptanone and an ethanol solution of ammonia for reaction catalyzed by an organo-metallic catalyst M, then adding sodium borohydride for reduction to prepare 4-heptylamine; synthesizing piperonyloyl chloride, as well as subjecting the synthesized 4-heptylamine with the synthesized piperonyloyl chloride to an amidation reaction so as to prepare N-(hept-4-yl) benzo [d] [1, 3] dioxole-5-methanamide. The synthetic method of the invention employs an organic metal-NaBH4 system to conduct a reductive amination reaction to a ketone compound so as to synthesize the important intermediate 4-heptylamine, and the generated primary amine no longer reacts with ketone, also the selectivity and yield are both high. In the method, the raw materials adopted are cheap and easily available, the solvent used can be recycled and utilized again, the production cost is low, and the reaction conditions are mild. With simple and convenient operation as well as little "three wastes", the method provided in the invention is suitable for industrial production.

The invention discloses a method for producing chemical fiber grade cyclohexanone. The method comprises the following steps of: putting a high-silicon-content HJT02 molecular sieve which is subjected to dealumnization treatment and aperture modification into an absorption column which is vertically arranged; allowing solvent type cyclohexanone to enter from the bottom of the absorption column andflow out from the upper part of the absorption column, and absorbing; and desorbing by using steam of the chemical fiber grade cyclohexanone after the absorption is finished. By the method, the totalamount of hexaldehyde and 2-heptanone in treated cyclohexanone is less than 36mg / kg, and the standard of chemical fiber grade ketone is reached; and the method has the advantages of low energy consumption and material consumption, and is an ideal method for producing the chemical fiber grade cyclohexanone.

The invention provides a quantitative detection method of rapeseed oil doped in edible oil, the method comprises the following steps: taking 2-methyl-3-heptanone as an internal standard, quantitatively detecting a characteristic volatile component cembrarene in a sample through SPME-GC / MS, calculating the ratio of the peak area corresponding to the separated matter cembrarene to the internal standard peak area, and calculating the relative content of the rapeseed oil in the sample through the standard curve so that quantitative detection of the content of the rapeseed oil in the sample is achieved. The method has the advantages of good reliability, simplicity, convenience and rapidness, and can relatively accurately analyze the content of the rapeseed oil in the edible vegetable oil and judge whether the edible vegetable oil is adulterated.

The invention discloses a synergism composition of phytochemicals controlling rice blast. The synergism composition of phytochemicals controlling the rice blast is made of citronellal and methyl heptanone. According to the synergism composition of phytochemicals controlling the rice blast, the citronellal and the methyl heptanone are compounded and mixedly applied, obvious synergism function are achieved on inhibition of mycelial growth and spore germination of the rice blast, the control efficiency can be up to about 70%, the controlling effect is obvious, dosage of pesticide can be lowered effectively, the labor intensity is decreased, the cost is saved, and the problem of pesticide abuse is solved. The synergism composition of phytochemicals controlling the rice blast is simple, particle, wide in material source, low in cost and good in using effect.

The invention provides an alkyl-substituted quinolinone compound with side chains. The alkyl-substituted quinolinone compound has a chemical structure represented by formula I, the name of the alkyl-substituted quinolinone compound is 2-(4'-methyl-)heptane-3-methyl-4(1H)-quinolinone, the chemical formula of the alkyl-substituted quinolinone compound is C18H22NO, and the alkyl-substituted quinolinone compound is named as heptanone. The invention further provides an application of pharmaceutical composition of the compound provided by the invention in preparation of drugs for prevention and / or treatment of gastritis caused by Helicobacter pylori. According to the alkyl-substituted quinolinone compound, a first-site N of the quinolinone is not hydroxylated, and a second-site of the quinolinone is substituted by 4-methyl-heptane; the quinolinone is prepared by utilizing total synthesis; and the compound, represented by the formula I and provided by the invention, has a relatively high selective inhibition effect on the Helicobacter pylori and is an efficient proton pump inhibitor, so that a possibility for developing a novel drug for treating the gastritis caused by the Helicobacter pylori is provided.

The invention discloses a method for preparing methyl heptanone. According to the method, 3-methyl-2-butene-1-ol and acetone undergoes a selective dehydrogenation coupling reaction under the action ofa rhodium catalyst, alkali and an optional assistant to generate methyl heptenone. Compared with the prior art, the method has the advantages that cheap and easily available 3-methyl-2-butene-1-ol and acetone are used as raw materials; the methyl heptenone with high additional value is prepared through a one-step reaction; and the method is high in atom utilization rate, low in generation of three wastes, mild in conditions and high in selectivity and yield.

The invention belongs to the technical field of medicines, relates to a novel diaryl heptane compound extracted from cortex juglandis mandshuricae, and discloses a method for preparing the compound and application. The specific preparation process comprises the following steps: performing alcohol extraction method, organic solvent extraction method, purification and enrichment of a Girard reagent, silica gel column chromatography separation, preparative HPLC separation and the like on cortex juglandis mandshurica to obtain one cyclic ether type diaryl heptane compound named as 3 ', 4'-epoxy-1-(4 '-methoxyphenyl)-7-(2' ', 6'-dihydroxy-3 ''-methoxyphenyl)-3-heptanone, and further comprises the following steps of: performing column chromatography on the cyclic ether type diaryl heptane compound to obtain the 3 ', 4'-epoxy-1-(4 '-methoxyphenyl)-7-(2' ', 6'-dihydroxy-3 ''-methoxyphenyl)-3-heptanone. The molecular formula of the compound is C21H24O6. In-vitro anti-tumor activity research shows that the compound has a certain inhibition effect on human cervical cancer cells Hela and human liver cancer cells HepG-2. The method for preparing the diaryl heptane compound is clear and controllable in operation, and the obtained compound is few in impurity and high in purity and has the application prospect of being developed into anti-tumor drugs.

The invention discloses a camphor-based enhanced fluorescent probe for detecting Fe2+ as well as a preparation method and application of the camphor-based enhanced fluorescent probe. The fluorescent probe is N,N-Dimethyl-4-(3-(4,7,7-trimethyl-3-oxybicyclo[2.2.1]hept-2-enyl)prop-1-en-1-yl)aniline oxide. The preparation method comprises the following steps: taking camphor as a raw material, carrying out condensation reaction on camphor and 4-dimethylamino cinnamyl aldehyde to obtain 3-(3-(4-(dimethylamino)phenyl)allylidene)-1,7,7-trimethylbicyclo[2.1.1]heptan-2-one. carrying out oxidation reaction on 3-(3-(4-(dimethylamino)phenyl)allylidene)-1,7,7-trimethylbicyclo[2.1.1]heptan-2-one and m-chloroperoxybenzoic acid to obtain N,N-Dimethyl-4-(3-(4,7,7-trimethyl-3-oxybicyclo[2.2.1]hept-2-enyl)prop-1-en-1-yl)aniline oxide. The compound can specifically recognize Fe2+, and solution fluorescence is changed from colorless to red under 365nm ultraviolet light, so that the compound can be used as an enhanced fluorescent probe for detecting Fe2+, the detection limit reaches 8.3 nM, the response time is within 40s, and the compound has a good application prospect.

The invention relates to new isolated Lactobacillus strains chosen from Lactobacillus mellifer Bin4NT (LMG P-28344) and Lactobacillus apinorum Fhon13NT (LMG P-28345), which have been isolated from honeybees or their processed food. The bacterial strains have unique properties such as production of benzene, free fatty acids and 2-heptanone, rendering them useful in many areas such as in food and beverage products, feed products and medical products.

A diphenyl heptanone compound, its production and use in pharmaceutical industry are disclosed. It can be used for reactivation gastritis, stomach erosio, gastric ulcer and duodenal ulcer.

The invention discloses a natural product combination for preventing and controlling rice blast efficiently. The natural product combination is composed of citral and methylheptanone. Through compounding and mixing of citral and rhodinal, the natural product combination has obvious synergistic effect on inhibiting mycelial growth and spore germination, preventing and controlling effect can reach about 70% and is remarkable, and insecticide consumption can be lowered effectively, so that labor intensity is reduced, cost is saved, and the problem of excessive insecticide application is solved. The plant essential oil is simple and easy in implementation, wide in material source, low in cost and good in using effect.

The invention discloses a method for preparing hinokitiol. The method includes the steps of conducting an addition reaction on bromoform and an initial raw material compound, namely cyclohexene, to obtain a first compound, namely 7,7-dibromo bicyclo[4.1.0]heptane; the first compound is subjected to an oxidization reaction to obtain a second compound, namely 3,7,7-tribromo bicyclo[4.1.0]heptyl-2-ketone; the second compound is subjected to a substitution reaction to obtain a third compound, namely 7,7-dibromo-3-hydroxy bicyclo[4.1.0] heptyl-3-alkene-2-ketone; the third compound is subjected to aring enlargement reaction to obtain a fourth compound, namely 4-bromo-2-hydroxy cycloheptyl-2,4,6-triene-1-ketone; the fourth compound is subjected to an alkylation reaction to obtain hinokitiol.