25 results about "Nonane" patented technology

The invention discloses a catalyst for preparing ultrahigh molecular weight polyoxyethylene as well as a preparation method and application thereof, and relates to the technical field of catalyst preparation. The preparation method of the catalyst comprises the following steps: S1, carrying out a reaction on 6-hexamethylenediamine and allyl acrylate to generate an intermediate 1, S2, carrying out a reaction on the intermediate 1 and diphenylphosphine to generate an intermediate 2, S3, carrying out a reaction on the intermediate 2 and allyl bromide to generate an intermediate 3, and S4, carrying out a reaction on the intermediate 3 and 9-boron bicyclo [3.3. 1] nonane. The prepared catalyst is high in catalytic activity, ultrahigh molecular weight polyoxyethylene can be prepared, and the molecular weight distribution of the prepared ultrahigh molecular weight polyoxyethylene is narrow.

The application provides a preparation method of 3,7-dinitro-1,3,5,7-tetraazabicyclononane, comprising the following steps: 1) feeding a first material comprising urea and concentrated sulfuric acid and a second material comprising fuming nitric acid and concentrated sulfuric acid into a microchannel reactor to perform a first-stage nitration reaction, to obtain a first-stage nitration reaction liquid; 2) feeding the first-stage nitration reaction liquid into a first tubular reactor to perform a second-stage nitration reaction, to obtain a second-stage nitration reaction liquid; 3) feeding the second-stage nitration reaction liquid and water into a second tubular reactor to perform a hydrolysis reaction, to obtain a hydrolysis liquid; 4) feeding the hydrolysis liquid and a third material comprising polyoxymethylene and ammonia water into a third tubular reactor to perform a condensation cyclization reaction, to obtain 3,7-dinitro-1,3,5,7-tetraazabicyclononane. The preparation method has the advantages of high safety, less waste pollution and simple operation.

This invention discloses an iron complex with a triazacyclic nonane macrocyclic skeleton, its preparation method, and its applications, belonging to the field of coordination chemistry. The iron complex has a triazacyclic nonane macrocyclic skeleton with two acetate side groups and one pyridine-N derivative side group. The iron complex exhibits excellent catalytic activity in the aerobic oxidation of N-aryltetrahydroisoquinoline, while also possessing good stability. The solvents for the catalytic reaction are water and acetonitrile, resulting in low pollution. This invention features mild reaction conditions, simple synthesis operations, and straightforward post-processing, meeting the requirements of environmental friendliness and clean production.

This invention relates to a polyisoprene-based phloroglucinol compound, its preparation method, and its applications, belonging to the field of pharmaceutical technology. The structural formula of the compound is shown below. The preparation method involves extracting the fruit of *Garcinia macrocarpa* in an aqueous organic solvent solution, followed by extraction with petroleum ether and dichloromethane, and then purifying the compound using silica gel column chromatography, ODS column chromatography, Sephadex LH-20 gel column chromatography, and semi-preparative high-performance liquid chromatography. The above method is simple and easy to implement, and the resulting compound has a novel structure with a [2,4,1]nonane core structure. It can promote the secretion of insulin in palmitic acid-induced pancreatic β-cells, showing promise for the preparation of drugs for the prevention and treatment of hyperglycemia.

The invention belongs to the technical field of fine fluorine chemical industry, and discloses a perfluoroalkane dielectric cooling liquid composition with customizable performance and a selective continuous preparation method thereof. The composition is composed of saturated derivatives of hexafluoropropylene oligomer and can comprise a perfluoro-branched hexane isomer mixture, a perfluoro-branched nonane isomer mixture and a perfluoro-branched alkane higher oligomer mixture with the polymerization degree not lower than 7, and key performance such as the boiling range, the viscosity and the freezing point can be customized by regulating and controlling the proportion of all the components. According to the preparation method, an integrated continuous flow system is adopted, and on-demand production of cooling liquid with different component proportions is realized through the steps of controllable initial oligomerization, selectable controllable chain growth and continuous saturation. The product provided by the invention has excellent comprehensive thermophysical properties, is suitable for immersed cooling of high-heat-flux electronic equipment such as an AI data center and a super computer, and has the advantages of high process platformization degree and good economical efficiency.

This invention relates to a room-temperature reactive silicone-containing matte semi-permanent release agent and its preparation method. The purpose of this invention is to solve the problems of existing release agents requiring one application per mold and high-temperature curing. The room-temperature reactive silicone-containing matte semi-permanent release agent is prepared by mass fraction of 30%–80% solvent, 10%–30% film-forming aid, 10%–20% spreading agent, 1%–10% film-forming agent, and 0.1%–2% catalyst. The film-forming aid is n-nonane and 2,6-dimethyloctane; the spreading agent is 1-ethyl-4-methylcyclohexane and 1,2,4-trimethylcyclohexane; and the film-forming agent is methoxy-terminated silicone resin and hydroxyl-terminated polymethylphenylsiloxane. The release agent prepared by this invention adheres firmly to the mold surface based on chemical bonding, exhibiting a low transfer rate during repeated demolding of the product, thus achieving "one-time coating, multiple demoldings".

The application discloses a kind of semi-fluorocarbon for removing emulsified silicone oil filling and its preparation method and application, comprising, olefin and perfluoroalkyl iodine are dissolved in acetonitrile, initiator is added and reacted under light source, to obtain fluorine-containing iodoalkane;Fluorine-containing iodoalkane is dissolved in isopropyl alcohol, and after adding reducing agent and heating reaction, it is washed to obtain semi-fluorocarbon with the structure of CF3 (CF2) 3 (CH2) 4CH3, named semi-fluorinated nonafluorononane;Wherein, the molar ratio of the olefin and perfluoroalkyl iodine is 1:1-1.4, and the initiator is cuprous chloride.The application controls the proportion of raw materials, carries out reaction under the condition of suitable initiator, simultaneously preferably zinc powder is used as reducing agent, effectively improves product purity and product yield, and operation process is simple, safe, and CF3 (CF2) 3 (CH2) 4CH3 prepared has not only good stability, but also good biocompatibility, no cytotoxicity, no skin sensitization, no acute eye irritation, can dissolve or wrap emulsified silicone oil droplets, and play a great role in the removal of emulsified silicone oil.

The invention discloses a novel silicate zeolite molecular sieve and a synthesis method thereof, and belongs to the technical field of silicate zeolite molecular sieves, the novel silicate zeolite molecular sieve comprises a silicon source, an aluminum source, an alkali source and a directing agent, the directing agent is composed of a diazabicyclo structure directing agent, a polycyclic nitrogen-containing cationic compound and a branched chain type surfactant; 1-fluoro-4-methyl-1, 4-diazabicyclo (2.2. 2) octane tetrafluoroborate or 6, 6-difluoro-1, 4-diazabicyclo (4.3. 0) nonane dihydrochloride is selected as the diazabicyclo structure directing agent, and a catalyst is selected as the diazabicyclo (2.2. 2) octane tetrafluoroborate or 6, 6-difluoro-1, 4-diazabicyclo (4.3. 0) nonane dihydrochloride. By adopting the guiding agent consisting of the diazabicyclo structure guiding agent, the polycyclic nitrogen-containing cationic compound and the branched chain type surfactant, the silicate zeolite molecular sieve with a unique pore structure, a high specific surface area and excellent catalytic performance can be synthesized, the catalytic efficiency is favorably improved, and the silicate zeolite molecular sieve can be used for preparing the 1, 2, 4-triazole compound. The 1, 2-cyclohexanediol is used as a raw material for dehydrogenation to prepare the catechol, so that the conversion rate of the 1, 2-cyclohexanediol and the selectivity of the catechol are improved.

The utility model provides a nitrogen supplementing device for diazaspiro-nonane-tert-butyl formate hydrochloride production, which comprises a base, the upper end of the base is fixedly connected with a supporting block, the middle part of the upper end of the supporting block is an arc-shaped concave surface, a gas cylinder is placed in the arc-shaped concave surface, the lower end of the base is provided with a fixed table, and the fixed table is provided with a gas cylinder. The fixing table comprises a fixing plate, a fixing hole is formed in the fixing plate in a penetrating mode, a guide rod is vertically and fixedly connected to the center of the interior of the base, a locking block of a cylindrical step structure is arranged on the guide rod in a sliding mode, the lower portion of the locking block is matched with the fixing hole, and a spring is arranged on the upper portion of the locking block. And the spring upwards abuts against the inner wall of the base, and the side wall of the upper portion of the locking block is fixedly connected with a shifting rod. According to the gas cylinder supporting device, the gas cylinder supporting stability can be improved, and meanwhile the placement occupied area is reduced.

Provided herein are crystalline forms of 5-(3,4-difluorobenzyl)-8-((1r,4r)-4-methylcyclohexyl)-6,9-dioxo-2,5,8-triazaspiro[3.5]nonane-2-carbaldehyde, compositions thereof, methods of preparation thereof, and methods of their uses.

The invention belongs to the technical field of preparation of medical intermediates, and particularly relates to a preparation method of a monomethyl impurity of an intermediate (S, S)-2, 8-diazabicyclo [4.3. 0] nonane of a quinolone antibacterial drug moxifloxacin hydrochloride, which comprises the following steps: by taking (S, R) 8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3. 0] nonane as an initial raw material, reacting at the temperature of 60-80 DEG C to obtain a monomethyl impurity of the intermediate (S, S)-2, 8-diazabicyclo [4.3. 0] nonane; a crude compound is obtained through condensation, reduction and debenzylation, and the crude compound is rectified, separated and purified to obtain the high-purity moxifloxacin side chain monomethyl impurity. The method has the characteristics that the synthesis route is short, the operation is simple, and the obtained moxifloxacin side chain monomethyl impurity product is high in purity and can be applied to research of impurity reference substances.

The invention provides a method for determining the content of a target component in coking crude benzene. The method for determining the content of the target component in the coking crude benzene comprises the following steps: mixing a coking crude benzene sample with internal standard substances 1, 4-dioxane and n-nonane, and injecting the mixture into a chromatographic instrument by adopting a capillary chromatographic column and taking methanol as a mobile phase to obtain a chromatogram and peak areas of all substances; calculating to obtain the content of the target component; the target components comprise benzene, toluene, ethylbenzene and xylene; wherein the xylene comprises p-xylene, m-xylene and o-xylene; the capillary chromatographic column comprises any one of a cross-linked and bonded polyethylene glycol quartz elastic capillary chromatographic column, a DB-1 chromatographic column and an HP-5 chromatographic column. According to the method disclosed by the invention, the component detection in the coking crude benzol is more accurate, the refining processing technology develops towards a more large-scale and multi-product deep processing direction, a higher additional value is generated, and the high-quality development of the industry is promoted.

The present invention provides a novel method for producing 1,9-nonane diol, with which 1,9-nonane diol can be efficiently produced with little environmental burden. This method for producing 1,9-nonane diol includes: (1) a step for blowing ozone gas into oleyl alcohol in such a way that ozone gas is blown until the ozone gas concentration at an outlet exceeds half the ozone gas concentration at an inlet, and the acid value of a treated product that has been treated with the ozone gas is 15 mg KOH / g or less; and (2) a step for hydrogenating, in the presence of a nickel catalyst, the treated product that has been treated with the ozone gas.

The invention discloses a polyurethane elastomer and a preparation method thereof. A soft segment of the polyurethane elastomer comprises polytetrahydrofuran, diisocyanate and 2, 7-diazaspiro [4.4] nonane which are combined to serve as a hard segment, and the 2, 7-diazaspiro [4.4] nonane high-strength polyurethane elastomer is obtained through a prepolymerization and chain extension two-step method. The elastomer is endowed with high glass transition temperature, high mechanical strength, high modulus and high chemical corrosion resistance through the super-rigid three-dimensional space constraint effect of a spiral ring and the strong hydrogen-bond interaction of allophanate.

The invention discloses a preparation method of a moxifloxacin hydrochloride intermediate with high yield, high purity and low cost, and aims to overcome the technical defects of low resolution yield, need of additional acid addition, single solvent system, complex resolution agent recovery process and limited salifying efficiency in the prior art. According to the method, cis-8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3. 0] nonane (a compound as shown in a formula I) is taken as a raw material, N-acetylphenylalanine (including L-type and D-type) is taken as a resolving agent, acid does not need to be additionally added in a water-alcohol-ester ternary solvent system, efficient resolution of the enantiomer is directly realized through a salt forming reaction, and the yield of the enantiomer is increased. And the high-purity diazabicyclo compounds shown in the formulas IIIa and IIIb can be obtained without a refining step. The resolution yield can reach 90% or above, the recovery process of the resolving agent is simple and efficient, the recovery rate is larger than or equal to 95%, the resolving agent can be stably and circularly applied for five times or above, the resolution yield is still larger than or equal to 90% after the resolving agent is applied, the comprehensive production cost is reduced by 40%-60% compared with the prior art, and the method has outstanding industrial application advantages.

The application provides a method for preparing normal paraffin from coal-based hydrorefined naphtha, which comprises the following steps: performing rectification separation on the coal-based hydrorefined naphtha to obtain C6 and above alkane; feeding the C6 and above alkane into a de-normal-hexane rectification tower to obtain crude normal hexane and C7 and above alkane; feeding the C7 and above alkane into a de-normal-heptane rectification tower to obtain crude normal heptane and C8 and above alkane; feeding the C8 and above alkane into a de-normal-octane rectification tower to obtain crude normal octane and C9 and above alkane; feeding the C9 and above alkane into a de-normal-nonane rectification tower to obtain crude normal nonane and C10 and above alkane; and performing rectification and deep hydrogenation on each crude normal paraffin to obtain normal hexane product, normal heptane product, normal octane product and normal nonane product. The technical scheme of the application uses coal-based hydrorefined naphtha as raw material, has a simple process flow and low energy consumption, and overcomes the problem of single product structure in the prior art.

This invention relates to a method for preparing 6-benzyl-1,2,3,4-tetrahydro-6H-pyrrolo[3,4-B]pyridine-5,7-dione and its application. The method for preparing 6-benzyl-1,2,3,4-tetrahydro-6H-pyrrolo[3,4-B]pyridine-5,7-dione involves reacting (1R,6S)-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4,3,0]nonane in an organic solvent under blue light irradiation with the aid of a photosensitizer and an oxidizing agent to obtain 6-benzyl-1,2,3,4-tetrahydro-6H-pyrrolo[3,4-B]pyridine-5,7-dione. This preparation method not only has mild reaction conditions, short reaction time, simple operation, and environmental friendliness, but also has high product conversion rate and good selectivity. It can be used for large-scale industrial production and can be better applied to the synthesis of moxifloxacin, thereby improving the utilization rate of raw materials in the synthesis of moxifloxacin.

The invention discloses a green synthesis method of moxifloxacin hydrochloride, which comprises the following steps: under a heating condition, reacting moxifloxacin cyclization ester with moxifloxacin ((S, S)-2, 8-diazabicyclo [4, 3, 0] nonane) in a solvent, alkali and catalyst system to obtain moxifloxacin ester, and then carrying out hydrolysis one-pot method in an acidic system to obtain the moxifloxacin hydrochloride. The moxifloxacin hydrochloride is directly prepared. The invention provides a green synthesis method of moxifloxacin hydrochloride. According to the green synthesis method, moxifloxacin is obtained through direct reaction of moxixane cyclization ester and moxixane. According to the method, the moxifloxacin serving as a target product is synthesized by taking the moxixane cyclization ester as a raw material without forming a chelate compound with boric acid ester and directly reacting with the moxixane through a one-pot method, no three wastes are generated in the preparation process, and the method has the advantages of short reaction steps, mild conditions, high yield and the like.

The application provides a high-pressure liquid supply system, comprising a low-pressure pipeline module, a high-pressure pump module, a high-pressure pipeline module and a control module; the low-pressure pipeline module comprises a liquid inlet pipeline and a liquid return pipeline, the inlet of the liquid inlet pipeline and the outlet of the liquid return pipeline are connected to a liquid source, and the outlet of the liquid inlet pipeline is connected to the inlet of the high-pressure pump module; the outlet of the high-pressure pump module is connected to the high-pressure pipeline module, so that the high-pressure pump module is used for pressurizing the inflowing liquid; the high-pressure pipeline module comprises multiple loops, one of which is used for supplying liquid to a demand side, and the other loops are connected to the liquid return pipeline after being combined; and the control module is used for controlling the working states of the low-pressure pipeline module, the high-pressure pump module and the high-pressure pipeline module. The application can realize automatic supply of high-pressure n-nonane liquid, realize real-time monitoring of temperature, pressure control and flow data of n-nonane, and achieve unattended operation.

The utility model provides a suction manifold and a fracturing truck. The suction manifold comprises a liquid inlet pipe, a filter and a suction manifold. The filter is used for filtering foreign matters in liquid, one end of the filter is connected with the liquid inlet pipe, the other end of the filter is connected with the suction manifold, the suction manifold comprises a main pipe and a plurality of connecting pipes arranged on the main pipe, and a cleaning union is arranged on the main pipe. According to the suction manifold, foreign matters in liquid sucked by the liquid inlet pipe can be filtered, and the working efficiency and the working stability of the suction manifold are improved.

The application discloses a water-based electrolyte and a zinc ion hybrid capacitor comprising the water-based electrolyte. The water-based electrolyte is a water-based electrolyte for a zinc ion hybrid capacitor, and comprises a zinc salt, an electrolyte additive and water. The electrolyte additive comprises a first additive and a second additive. The first additive is an organic antifreezing agent, and the second additive is a heterocyclic nonane. The volume fraction of the organic antifreezing agent in the water-based electrolyte is greater than 0.1% and less than 40%. The water-based electrolyte of the application uses the organic antifreezing agent and the heterocyclic nonane as additives, and the two cooperate with each other. The water-based electrolyte can not only prevent freezing and avoid ice formation, but also modify the zinc negative electrode interface, reduce the Zn 2+ reduction rate, alleviate concentration polarization, thereby facilitating inhibition of dendrite growth, and can also inhibit the side reaction of the zinc negative electrode, thereby improving the low-temperature cycle performance of the zinc ion hybrid capacitor.