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The invention provides reinforced aerogel monoliths as well as reinforced composites thereof for a variety of uses. Compositions and methods of preparing the monoliths and composites are also provided. Application of these materials in transparent assemblies is also discuss.

Oligonucleotide analogues comprising modified intersubunit linkages and / or modified 3′ and / or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

A polypropylene composition for the production of various molded articles which are excellent in moldability, mold shrinkage factor on molding, rigidity, flexibility, impact resistance, in particular low-temperature impact resistance, transparency, gloss, stress-whitening resistance, and the balance thereof; various molded articles having the above properties; a propylene composition which is suitable for a base resin for the polypropylene composition; and a process for the production thereof. The propylene composition comprises a propylene homopolymer and a propylene-ethylene copolymer, the intrinsic viscosity of the copolymer ([eta]RC) is in the range of 1.7 to 2.8 dl / g, the intrinsic viscosity ratio of the homopolymer to the copolymer ([eta]RC / [eta]pp) is in the range of 0.7 to 1.2 and a product [(WPP / WRC)x([eta]RC / [eta]pp)] of the weight ratio (WPP / WRC) of the homopolymer to the copolymer and the intrinsic viscosity ratio thereof is in the range of 1.0 to 3.0.

This invention relates primarily to a therapeutic method comprising the use of a flexible outer cover that allows quick and easy alternating insertions of separate heat and cold packs, and is attached using an adhesive layer or safety pins to a garment at a location on the garment that is in close contact with an injured area of the body when the garment is worm, to provide alternating cold and hot or hot and cold therapeutic treatments and to a contrasting thermal device comprising a flexible outer cover for use in this method, and an article of manufacture comprising said flexible outer cover and other optional elements to form said contrasting thermal device.

A high-yield process for converting lignin into reformulated, partially oxygenated gasoline compositions of high quality is provided. The process is a two-stage catalytic reaction process that produces a reformulated, partially oxygenated gasoline product with a controlled amount of aromatics. In the first stage of the process, a lignin feed material is subjected to a base-catalyzed depolymerization reaction, followed by a selective hydrocracking reaction which utilizes a superacid catalyst to produce a high oxygen-content depolymerized lignin product mainly composed of alkylated phenols, alkylated alkoxyphenols, and alkylbenzenes. In the second stage of the process, the depolymerized lignin product is subjected to an exhaustive etherification reaction, optionally followed by a partial ring hydrogenation reaction, to produce a reformulated, partially oxygenated / etherified gasoline product, which includes a mixture of substituted phenyl / methyl ethers, cycloalkyl methyl ethers, C7-C10 alkylbenzenes, C6-C10 branched and multibranched paraffins, and alkylated and polyalkylated cycloalkanes.

An endoscopic shaft having multiple endoscopic elements set in a polymer common housing. The endoscopic elements may be drawn with the common housing to manufacture a component, called an EndoFiber, which forms the length of the endoscopic shaft. A second structure, called an Endocap, may be provided that includes optical elements and which is attached to the end of the EndoFiber to form the shaft.

The invention provides asymmetric membranes composed of a microporous substrate whose pores contain a crosslinked gel, the density of the crosslinked gel being greater at or adjacent to one major surface of the membrane than the density at the other major surface. The membranes are useful for separating matter from liquids and display good flux and good rejection at low pressure.

The present disclosure provides a touch panel and a display device employing the same. The touch panel includes at least one transparent layer consisting of a carbon nanotube metal composite layer including a carbon nanotube layer and a metal layer coated on the carbon nanotube layer.

The invention provides asymmetric membranes composed of a microporous substrate whose pores contain a crosslinked gel, the density of the crosslinked gel being greater at or adjacent to one major surface of the membrane than the density at the other major surface. The membranes are useful for separating matter from liquids and display good flux and good rejection at low pressure.

A light-weight, heat distortion resistant laminate includes at least one layer of an alkali silicate resin composition derived from an alkali silicate and / or alkali silicate precursor, at least one oxoanionic compound or a reactive acidic glass; and water; and at least one reinforcing core layer comprising an inorganic high-temperature resistant composition. The laminate has a very low quench steepness index value upon rapid quenching as with ambient temperature water.

The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition, including Crohn's disease and ulcerative colitis, and cancer.

A pharmaceutical composition which comprises an insulin sensitizer in combination with an anorectic, which is useful as an agent for preventing or treating diabetes.

The invention provides an optoelectronic device comprising a porous material, which porous material comprises a semiconductor comprising a perovskite. The porous material may comprise a porous perovskite. Thus, the porous material may be a perovskite material which is itself porous. Additionally or alternatively, the porous material may comprise a porous dielectric scaffold material, such as alumina, and a coating disposed on a surface thereof, which coating comprises the semiconductor comprising the perovskite. Thus, in some embodiments the porosity arises from the dielectric scaffold rather than from the perovskite itself. The porous material is usually infiltrated by a charge transporting material such as a hole conductor, a liquid electrolyte, or an electron conductor. The invention further provides the use of the porous material as a semiconductor in an optoelectronic device. Further provided is the use of the porous material as a photosensitizing, semiconducting material in an optoelectronic device. The invention additionally provides the use of a layer comprising the porous material as a photoactive layer in an optoelectronic device. Further provided is a photoactive layer for an optoelectronic device, which photoactive layer comprises the porous material.

A carbon fiber having a lattice spacing (d002) of 0.336 nm to 0.338 nm and a crystallite size (Lc002) of 50 nm to 150 nm as measured and evaluated by X-ray diffraction and a fiber diameter of 10 nm to 500 nm, the carbon fiber having no branched structure.

The present invention relates to solvent-free processes for the preparation of mono-substituted fluorinated oxetane monomers. Once prepared, the mono-substituted fluorinated oxetane monomers can be used to prepare prepolymers and polymers having fluorinated alkoxymethylene side chains.

The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition including Crohn's disease and ulcerative colitis, and cancer.

Oligonucleotide analogues comprising modified intersubunit linkages and / or modified 3′ and / or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition including Crohn's disease and ulcerative colitis, and cancer.

This invention provides an aligned single-walled CNT aggregate comprising a substrate, fine particles of iron catalyst with a density of 1×1011 to 1×1014 / cm2 disposed on an alumina co-catalyst above the substrate, and a plurality of single-walled CNTs grown from the fine particles of the iron catalyst, in which the plurality of single-walled CNTs have a specific surface area of 600 m2 / g to 2600 m2 / g, and a weight density from 0.002 g / cm3 to 0.2 g / cm3, and the alignment degree which satisfies a few of specific conditions. This invention also provides a bulk aligned single-walled carbon nanotube aggregate and a powdered aligned single-walled carbon nanotube aggregate.

The invention concerns inter alia an implant for vessel ligature, the implant which comprises an alloy, wherein the alloy is at least partially biodegradable, and wherein the alloy comprises: greater than 87% magnesium; from about 3% to about 6% yttrium; from about 1% to about 5% lanthanide; and a balance of about 0.0% to about 2%.

A recording medium containing a substantially colorless compound in which at least 10 atoms having conjugate π electrons are present on a per-molecule basis, wherein it is especially preferable that the compound has at least two aromatic ring groups and / or shows no fluorescence. An ink composition used for printing in image form on media, with the composition containing a dye and controlling a hue change caused in the printed images over a period of one hour immediately after the printing to 5 or below in color-difference terms. And a method of recording images on media by printing an ink composition in image form, wherein the ink composition contains a dye and a hue change caused in the printed images over a period of one hour immediately after the printing is controlled to 5 or below in color-difference terms.

Transparent conductive films for flat panel displays and methods for producing them are disclosed. In general, a method according to the present invention comprises: (1) providing a flexible plastic substrate; (2) depositing a multi-layered conductive metallic film on the flexible plastic substrate by a thin-film deposition technique to form a composite film, the multi-layered conductive metallic film comprising two layers of an alloy selected from the group consisting of indium cerium oxide (InCeO) and indium tin oxide (ITO) surrounding a layer of an alloy of silver, palladium, and copper (Ag / Pd / Cu); and (3) collecting the composite film in continuous rolls. Typically, the thin-film deposition technique is DC magnetron sputtering. Another aspect of the invention is a composite film produced by a method according to the present invention. Still another aspect of the invention is a composite film comprising a multilayered film as described above formed on a flexible plastic substrate, wherein the composite film has a combination of properties including: transmittance of at least 80% throughout the visible region; an electrical resistance of no greater than about 10 Omega / square; a root-mean-square roughness of no greater than about 2.5 nm; and an interlayer adhesion between the multi-layered metallic film and the remainder of the composite film that is sufficiently great to survive a 180° peel adhesion test.

A low cost moisture curable sealer and adhesive composition containing a polymer having reactive silyl groups and a bituminous material and having many advantages over conventional moisture cure sealer compositions, including greater elastomeric properties, improved flexibility and pliability, lower durometer, faster and deeper cure, low temperature cure. The composition is also free of carcinogens such as coal tar, toxic isocyanates, and volatile solvents.

The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition including Crohn's disease and ulcerative colitis, and cancer.

There is provided a conductive material comprising a base material made up of a Cu strip, a Cu—Sn alloy covering layer formed over a surface of the base material, containing Cu in a range of 20 to 70 at.%, and having an average thickness in a range of 0.1 to 3.0 μm, and an Sn covering layer formed over the Cu—Sn alloy covering layer having an average thickness in a range of 0.2 to 5.0 μm, disposed in that order, such that portions of the Cu—Sn alloy covering layer are exposed the surface of the Sn covering layer, and a ratio of an exposed area of the Cu—Sn alloy covering layer to the surface of the Sn covering layer is in a range of 3 to 75%. The surface of the conductive material is subjected to a reflow process and preferably, an arithmetic mean roughness Ra of the surface of the material in at least one direction, is not less than 0.15 μm while the arithmetic mean roughness Ra thereof, in all directions, is not more than 3.0 μm and the average thickness of the Cu—Sn alloy covering layer is preferably not less than 0.2 μm. The conductive material is fabricated by a method whereby the surface of the base material is subjected to roughening treatment, an Ni plating layer, a Cu plating layer and an Sn plating layer are formed, as necessary, over the surface of the base material, and subsequently, a reflow process is applied.

Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and / or modified 3′ and / or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.