In a surgical instrument for placement of C-shaped ligature clips having two legs running next to one another and connected to one another by means of a bridge-section, with two clamping jaws movable relative to one another, with a supply guide means, along which the ligature clip can be pushed onto the clamping jaws with the free ends of the legs first, with a clamping jaw guide means, which adjoins the supply guide means and in which the ligature clip can be inserted between the clamping jaws, and with a feeding means for advancing a ligature clip out of the supply guide means into the clamping jaw guide means and into an end position between the clamping jaws, in order to improve the guidance of the ligature clips during transfer from the supply guide means into the clamping jaw guide means, it is proposed that the feeding means comprises a feed element, which can be placed against the ligature clip to be fed and is guided in a longitudinal guide means running along its feed path in the transition region from the supply guide means into the clamping jaw guide means.