Pharmaceutical composition for the treatment of diabetes
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
Example
In the similar manner to Reference Example 1, 140000 tablets having the following composition and each containing 30 mg of pioglitazone were obtained.
Example
REFERENCE EXAMPLE 3
In the similar manner to Reference Example 2, 140000 tablets having the following composition and each containing 45 mg of pioglitazone were obtained.
Example
EXAMPLE 1
Effects of concomitant administration of pioglitazone hydrochloride and mazindol in noninsulin-dependent diabetic mellitus (NIDDM) patients were studied.
When pioglitazone hydrochloride (45 mg / day, oral administration) was concomitantly administered to a NIDDM patient [one sample(man); 44 years old; body weight 99.0 kg; fasting blood sugar 242.0 mg / dl; HbA.sub.1c 11.0%] under treatment with mazindol (1.0 mg / day, oral administration) over the period of 8 weeks, fasting blood sugar decreased by 70.0 mg / dl, HbA.sub.1c decreased by 2.00%, and body weight decreased by 1.00 kg.
When placebo (oral administration) was administered to NIDDM patients [55 samples (20 men and 35 women); 37 to 73 years old (57.9.+-.8.7 (means.+-.standard deviation) years old; body weight 59.8.+-.12.1 (means.+-.standard deviation of 54 samples) kg; fasting blood sugar 180.1 .+-.23.0 (means.+-.standard deviation) mg / dl; HbA.sub.1c 8.8.+-.1.3 (means.+-.standard deviation) %] over the period of 12 .+-.2 weeks...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap